KEGG   Heterocephalus glaber (naked mole-rat): 101696390
Entry
101696390         CDS       T02812                                 
Name
(RefSeq) caspase-3
  KO
K02187  caspase 3 [EC:3.4.22.56]
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl01524  Platinum drug resistance
hgl04010  MAPK signaling pathway
hgl04115  p53 signaling pathway
hgl04148  Efferocytosis
hgl04210  Apoptosis
hgl04215  Apoptosis - multiple species
hgl04623  Cytosolic DNA-sensing pathway
hgl04650  Natural killer cell mediated cytotoxicity
hgl04657  IL-17 signaling pathway
hgl04668  TNF signaling pathway
hgl04726  Serotonergic synapse
hgl04932  Non-alcoholic fatty liver disease
hgl04933  AGE-RAGE signaling pathway in diabetic complications
hgl04936  Alcoholic liver disease
hgl05010  Alzheimer disease
hgl05012  Parkinson disease
hgl05014  Amyotrophic lateral sclerosis
hgl05016  Huntington disease
hgl05020  Prion disease
hgl05022  Pathways of neurodegeneration - multiple diseases
hgl05132  Salmonella infection
hgl05133  Pertussis
hgl05134  Legionellosis
hgl05145  Toxoplasmosis
hgl05146  Amoebiasis
hgl05152  Tuberculosis
hgl05160  Hepatitis C
hgl05161  Hepatitis B
hgl05162  Measles
hgl05163  Human cytomegalovirus infection
hgl05164  Influenza A
hgl05165  Human papillomavirus infection
hgl05167  Kaposi sarcoma-associated herpesvirus infection
hgl05168  Herpes simplex virus 1 infection
hgl05169  Epstein-Barr virus infection
hgl05170  Human immunodeficiency virus 1 infection
hgl05200  Pathways in cancer
hgl05203  Viral carcinogenesis
hgl05205  Proteoglycans in cancer
hgl05206  MicroRNAs in cancer
hgl05210  Colorectal cancer
hgl05222  Small cell lung cancer
hgl05416  Viral myocarditis
hgl05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101696390
   04668 TNF signaling pathway
    101696390
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    101696390
  09143 Cell growth and death
   04210 Apoptosis
    101696390
   04215 Apoptosis - multiple species
    101696390
   04115 p53 signaling pathway
    101696390
 09150 Organismal Systems
  09151 Immune system
   04623 Cytosolic DNA-sensing pathway
    101696390
   04650 Natural killer cell mediated cytotoxicity
    101696390
   04657 IL-17 signaling pathway
    101696390
  09156 Nervous system
   04726 Serotonergic synapse
    101696390
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101696390
   05206 MicroRNAs in cancer
    101696390
   05205 Proteoglycans in cancer
    101696390
   05203 Viral carcinogenesis
    101696390
  09162 Cancer: specific types
   05210 Colorectal cancer
    101696390
   05222 Small cell lung cancer
    101696390
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101696390
   05161 Hepatitis B
    101696390
   05160 Hepatitis C
    101696390
   05164 Influenza A
    101696390
   05162 Measles
    101696390
   05168 Herpes simplex virus 1 infection
    101696390
   05163 Human cytomegalovirus infection
    101696390
   05167 Kaposi sarcoma-associated herpesvirus infection
    101696390
   05169 Epstein-Barr virus infection
    101696390
   05165 Human papillomavirus infection
    101696390
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101696390
   05133 Pertussis
    101696390
   05134 Legionellosis
    101696390
   05152 Tuberculosis
    101696390
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    101696390
   05145 Toxoplasmosis
    101696390
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101696390
   05012 Parkinson disease
    101696390
   05014 Amyotrophic lateral sclerosis
    101696390
   05016 Huntington disease
    101696390
   05020 Prion disease
    101696390
   05022 Pathways of neurodegeneration - multiple diseases
    101696390
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101696390
   05416 Viral myocarditis
    101696390
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101696390
   04932 Non-alcoholic fatty liver disease
    101696390
   04933 AGE-RAGE signaling pathway in diabetic complications
    101696390
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101696390
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hgl01002]
    101696390
Enzymes [BR:hgl01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.56  caspase-3
     101696390
Peptidases and inhibitors [BR:hgl01002]
 Cysteine peptidases
  Family C14: caspase family
   101696390
SSDB
Motif
Pfam: Peptidase_C14
Other DBs
NCBI-GeneID: 101696390
NCBI-ProteinID: XP_012923258
UniProt: A0AAX6QPN8
LinkDB
Position
Un
AA seq 277 aa
MENTENSVDTKSMKDLETKIIHRSKSMDSGISLDNRYKMDYPEIGLCIIINNKNFHRSTG
MSARSGTDVDAANLREIFMNLKYEVRNKNDLKCEEIVKLMCSVSKEDHSKRSSFICVILS
HGEEGIIFGTNGPIDLKILTKFFRGDLCRSLAGKPKLFIIQACQGTELDSGTKTDSGIDD
DMACQKIPVEADFLYAYSTAPGYHSWRNSKDGSWFIQSLCATVKLYAHNLEFMHILTRVN
RKVATEFESFSYDSTFRPKKQIPCIVSMLTKELYFYH
NT seq 834 nt   +upstreamnt  +downstreamnt
atggagaacactgaaaactcagtggatacaaaatccatgaaagatttagaaacaaagatc
atacacagaagcaaatcaatggactctggaatatccttggataatagatacaaaatggat
tatcctgaaataggtttatgcataattattaataataagaactttcatagaagcactgga
atgtcagctcgatctggtacagatgtagatgcagcaaacctcagagaaatatttatgaac
ttgaaatatgaagtgaggaataaaaatgatcttaagtgtgaagaaattgtgaaattgatg
tgcagtgtttctaaagaagatcatagcaaaaggagcagctttatttgtgtaattctaagc
catggtgaagaaggaataatttttggaacaaatggacccattgacctgaaaatattaaca
aaattcttcagaggggatctttgtagaagtctagctggaaaacccaaacttttcattatt
caggcctgccagggtacagaactggactctggcactaagacagacagtggtattgatgat
gacatggcgtgccagaaaataccagtagaggctgacttcttgtatgcatattccacggca
ccaggttaccattcctggcgaaattcaaaggatggatcctggttcattcagtcactttgt
gctacggtgaaattgtatgcacacaaccttgagtttatgcacattcttactcgggttaac
cggaaggtagcaacagaatttgaatccttttcctatgactccacttttcgtccaaagaaa
caaattccatgtattgtgtccatgctcacaaaagaactatatttttatcactaa

DBGET integrated database retrieval system