Hyaena hyaena (striped hyena): 120221929 Help Entry 120221929         CDS       T07257                                  Name (RefSeq) steroid 21-hydroxylase   KO K00513   steroid 21-monooxygenase [EC:1.14.14.16] Organism hhv  Hyaena hyaena (striped hyena) Pathway hhv00140   Steroid hormone biosynthesis hhv01100   Metabolic pathways hhv04925   Aldosterone synthesis and secretion hhv04927   Cortisol synthesis and secretion hhv04934   Cushing syndrome Module hhv_M00109   C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone Brite KEGG Orthology (KO) [BR:hhv00001]  09100 Metabolism   09103 Lipid metabolism    00140 Steroid hormone biosynthesis     120221929  09150 Organismal Systems   09152 Endocrine system    04925 Aldosterone synthesis and secretion     120221929    04927 Cortisol synthesis and secretion     120221929  09160 Human Diseases   09167 Endocrine and metabolic disease    04934 Cushing syndrome     120221929  09180 Brite Hierarchies   09181 Protein families: metabolism    00199 Cytochrome P450 [BR:hhv00199]     120221929 Enzymes [BR:hhv01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor     1.14.14.16  steroid 21-monooxygenase      120221929 Cytochrome P450 [BR:hhv00199]  Cytochrome P450, animal type   CYP21 family    120221929 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  p450 Motif Other DBs NCBI-GeneID:  120221929 NCBI-ProteinID:  XP_039075539 LinkDB All DBs Position Unknown AA seq 492 aa AA seqDB search MLLLALLLLTMLAGACLLWDKWKYRSLHLPPLAPGFLHLLQPDLPIYLLGLTQKLGPVYR LRLGLQDVVVLNSKRTIEEAMIRRWVDFAGRPKMPSYKLVSQDHQDLSLGDYSLLWKAHK KLTRSALLLGIRNSMEPLVEQMTREFCERMRAQAGTPVAIQKEFSFLTCSIICYLTFGDK EDTLVHVFHDCVHDLMKTWEHWSIQILDIVPFLRFFPNPGLWRLKQALEKRDRIVEKQLK QHKDRMVAGQWRDMTDYMLQGVGKPRAERGHGRLLEGHVHMSVVDLFIGGTETTATTLSW AVAFLLHHPEIQQRLQEELDRELGPGISGSRVPFKDPARLPLLTATIAEVLRLRPVVPLA LPHRTTRHSSILGYDIPEGTVVIPNLQGAHLDENVWERPHEFWPDRFLVPGASPRVLAFG CGARVCLGEPLARLELFVVLARLLHTFTLLPPAGPLPSLQPRSHSGVNLTMQPFQVRLLP RGTDVLGLEQPQ NT seq 1479 nt NT seq  +upstreamnt  +downstreamnt atgctacttcttgcgctgctgctgctgaccatgctggccggcgcctgcctgctgtgggac aagtggaagtacaggagcctccacctcccacctcttgctcctggcttcctgcacctactg cagcccgaccttcccatctatctgcttggtctgactcagaaactcggccctgtctatagg ctccgcctcgggctgcaagatgtggtggtgctgaactctaaaaggaccattgaggaggcc atgatcaggagatgggtggactttgctggcagacccaagatgccctcctataagctggta tctcaggaccaccaggacctctcactaggggactactccttgctctggaaggctcacaag aaactcacccgctcagccctgctgctgggcatccgcaactccatggagccactggtggag caaatgacccgggagttttgtgagcgcatgagagcccaggccggcacccctgtggccatc cagaaggagttctctttcctcacctgcagtatcatctgttacctcacctttggagacaag gaagacaccttagtacatgtctttcatgactgtgtccacgatttgatgaaaacctgggag cactggtccattcaaattttggacatagttccctttctcaggttcttccccaacccaggc ctctggaggttgaagcaggccttggagaaaagggaccgcattgtagagaagcagctgaag cagcacaaggacagaatggtggcaggccagtggagggacatgactgactacatgctccaa ggggtggggaagccaagagcagaaaggggccatggacggctccttgaaggacacgtgcat atgtctgtggtggaccttttcattggtggcactgagacgacggcgaccaccctctcctgg gctgtggcattcttgcttcaccaccctgagattcagcagcgactgcaggaggaactggat cgtgaactaggccctgggatttcgggctcccgagtcccgttcaaagaccctgcacggctg cccttgctcaccgccaccattgctgaggtgctgcgcctgcgacccgtggtgcccctggcc ttgcctcaccgcaccactcggcatagcagcatcttaggctacgacatccccgagggcacg gttgtcatccccaacctgcaaggcgcccacttggatgagaacgtctgggagcggccacac gagttctggccggatcgtttcctggtcccaggcgccagccccagagttctggcctttggc tgcggggcacgtgtgtgcctgggcgagccgctggcacgcctcgagctctttgtggtgctg gcacggctgctccacaccttcacgttgctgccccccgcgggccctctaccctctctgcaa cccagatcccactctggcgtcaacctcacgatgcagcctttccaggtgcggctactgccc cggggaacagacgttctggggctggagcagccccagtga

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