Hyaena hyaena (striped hyena): 120246375 Help Entry 120246375         CDS       T07257                                  Symbol CASP3 Name (RefSeq) caspase-3 isoform X1   KO K02187   caspase 3 [EC:3.4.22.56] Organism hhv  Hyaena hyaena (striped hyena) Pathway hhv01524   Platinum drug resistance hhv04010   MAPK signaling pathway hhv04115   p53 signaling pathway hhv04148   Efferocytosis hhv04210   Apoptosis hhv04215   Apoptosis - multiple species hhv04623   Cytosolic DNA-sensing pathway hhv04650   Natural killer cell mediated cytotoxicity hhv04657   IL-17 signaling pathway hhv04668   TNF signaling pathway hhv04726   Serotonergic synapse hhv04932   Non-alcoholic fatty liver disease hhv04933   AGE-RAGE signaling pathway in diabetic complications hhv04936   Alcoholic liver disease hhv05010   Alzheimer disease hhv05012   Parkinson disease hhv05014   Amyotrophic lateral sclerosis hhv05016   Huntington disease hhv05020   Prion disease hhv05022   Pathways of neurodegeneration - multiple diseases hhv05132   Salmonella infection hhv05133   Pertussis hhv05134   Legionellosis hhv05145   Toxoplasmosis hhv05146   Amoebiasis hhv05152   Tuberculosis hhv05160   Hepatitis C hhv05161   Hepatitis B hhv05162   Measles hhv05163   Human cytomegalovirus infection hhv05164   Influenza A hhv05165   Human papillomavirus infection hhv05167   Kaposi sarcoma-associated herpesvirus infection hhv05168   Herpes simplex virus 1 infection hhv05169   Epstein-Barr virus infection hhv05170   Human immunodeficiency virus 1 infection hhv05200   Pathways in cancer hhv05203   Viral carcinogenesis hhv05205   Proteoglycans in cancer hhv05206   MicroRNAs in cancer hhv05210   Colorectal cancer hhv05222   Small cell lung cancer hhv05416   Viral myocarditis hhv05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:hhv00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     120246375 (CASP3)    04668 TNF signaling pathway     120246375 (CASP3)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     120246375 (CASP3)   09143 Cell growth and death    04210 Apoptosis     120246375 (CASP3)    04215 Apoptosis - multiple species     120246375 (CASP3)    04115 p53 signaling pathway     120246375 (CASP3)  09150 Organismal Systems   09151 Immune system    04623 Cytosolic DNA-sensing pathway     120246375 (CASP3)    04650 Natural killer cell mediated cytotoxicity     120246375 (CASP3)    04657 IL-17 signaling pathway     120246375 (CASP3)   09156 Nervous system    04726 Serotonergic synapse     120246375 (CASP3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     120246375 (CASP3)    05206 MicroRNAs in cancer     120246375 (CASP3)    05205 Proteoglycans in cancer     120246375 (CASP3)    05203 Viral carcinogenesis     120246375 (CASP3)   09162 Cancer: specific types    05210 Colorectal cancer     120246375 (CASP3)    05222 Small cell lung cancer     120246375 (CASP3)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     120246375 (CASP3)    05161 Hepatitis B     120246375 (CASP3)    05160 Hepatitis C     120246375 (CASP3)    05164 Influenza A     120246375 (CASP3)    05162 Measles     120246375 (CASP3)    05168 Herpes simplex virus 1 infection     120246375 (CASP3)    05163 Human cytomegalovirus infection     120246375 (CASP3)    05167 Kaposi sarcoma-associated herpesvirus infection     120246375 (CASP3)    05169 Epstein-Barr virus infection     120246375 (CASP3)    05165 Human papillomavirus infection     120246375 (CASP3)   09171 Infectious disease: bacterial    05132 Salmonella infection     120246375 (CASP3)    05133 Pertussis     120246375 (CASP3)    05134 Legionellosis     120246375 (CASP3)    05152 Tuberculosis     120246375 (CASP3)   09174 Infectious disease: parasitic    05146 Amoebiasis     120246375 (CASP3)    05145 Toxoplasmosis     120246375 (CASP3)   09164 Neurodegenerative disease    05010 Alzheimer disease     120246375 (CASP3)    05012 Parkinson disease     120246375 (CASP3)    05014 Amyotrophic lateral sclerosis     120246375 (CASP3)    05016 Huntington disease     120246375 (CASP3)    05020 Prion disease     120246375 (CASP3)    05022 Pathways of neurodegeneration - multiple diseases     120246375 (CASP3)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     120246375 (CASP3)    05416 Viral myocarditis     120246375 (CASP3)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     120246375 (CASP3)    04932 Non-alcoholic fatty liver disease     120246375 (CASP3)    04933 AGE-RAGE signaling pathway in diabetic complications     120246375 (CASP3)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     120246375 (CASP3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:hhv01002]     120246375 (CASP3) Enzymes [BR:hhv01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.56  caspase-3      120246375 (CASP3) Peptidases and inhibitors [BR:hhv01002]  Cysteine peptidases   Family C14: caspase family    120246375 (CASP3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 Motif Other DBs NCBI-GeneID:  120246375 NCBI-ProteinID:  XP_039109781 LinkDB All DBs Position Unknown AA seq 278 aa AA seqDB search MEGSENSVDAKSIKNSEPRKIFHGSKSMDSGIYLDNSYKMDYPEMGLCIIINNKNFHEST GMPSRSGTDVDAANLRETFTNLKYEVRNKNDLTREQIVALLDSVSREDHSKRSSFVCVLL SHGDEGIIYGTNGPLDLKKLTSFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSGTE DDIACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCSMLRLYAHKLEFMHILTRV NRKVALEFESFSLDSVFHGKKQIPCIVSMLTKELYFYH NT seq 837 nt NT seq  +upstreamnt  +downstreamnt atggagggcagtgaaaactcagtggatgcaaaatccattaaaaattcagaacccagaaag atcttccatggaagcaaatcaatggactccggaatatacttggacaacagttacaaaatg gattatcctgaaatgggtttatgtataataattaataataagaactttcatgaaagtact ggaatgccatctcgctctggtacagatgtggatgcggcgaacctccgggaaaccttcaca aacttgaaatacgaagtcaggaataaaaacgatcttacacgtgaacaaatcgtggcattg ctggacagtgtgtccagagaagatcatagcaagaggagcagttttgtttgcgtgcttcta agccacggtgatgaaggaatcatttatggaacaaatggacctcttgacctgaaaaaatta acaagtttcttcagaggggactattgtagaagtctaaccggcaaacccaaacttttcatt attcaggcctgtcgaggcacagaactggactgtggcattgagactgacagtggtaccgag gatgacattgcctgtcagaaaatcccagtggaagccgacttcttatatgcgtattctaca gcccctggttactactcctggcgaaattccaaggatggatcctggttcatccagtcactt tgttcgatgctcagactatatgctcacaagcttgagttcatgcacattcttactcgggtt aaccgaaaggtagctctagaatttgagtccttttctcttgactctgtttttcatggaaag aaacagattccgtgtattgtatctatgctcacaaaagaactgtatttttatcactaa

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