Hylobates moloch (silvery gibbon): 116469148
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Entry
116469148 CDS
T08803
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase isoform X1
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
hmh
Hylobates moloch (silvery gibbon)
Pathway
hmh00350
Tyrosine metabolism
hmh00790
Folate biosynthesis
hmh01100
Metabolic pathways
hmh04728
Dopaminergic synapse
hmh04917
Prolactin signaling pathway
hmh05012
Parkinson disease
hmh05030
Cocaine addiction
hmh05031
Amphetamine addiction
hmh05034
Alcoholism
Module
hmh_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
hmh00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
116469148 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
116469148 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
116469148 (TH)
09156 Nervous system
04728 Dopaminergic synapse
116469148 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
116469148 (TH)
09165 Substance dependence
05030 Cocaine addiction
116469148 (TH)
05031 Amphetamine addiction
116469148 (TH)
05034 Alcoholism
116469148 (TH)
Enzymes [BR:
hmh01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
116469148 (TH)
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Paralog
GFIT
Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
116469148
NCBI-ProteinID:
XP_032009701
LinkDB
All DBs
Position
Unknown
AA seq
528 aa
AA seq
DB search
MPTPDATTPQAKGFRRAVSELDAKQAEAIMVRGQGDPGPSLTGSPWPGTAAPAASYTPTP
RSPRFIGRRQSLIEDARKEREAAVAAAAAAAPLEPGDPLEAMAFEEKEGKAVLNLLFSLR
ATKPSALSRAVKVLETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVPRGDLSALLSGVR
QVSEDVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAEI
AFQYRHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHLEAFALLERFSGYREDNI
PQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCC
HELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLCKQNGEVKAYG
AGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSDAKDKLRSYAS
RIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAIG
NT seq
1587 nt
NT seq
+upstream
nt +downstream
nt
atgcccacccccgacgccaccacgccacaggccaagggcttccgcagggccgtgtctgag
ctggacgccaagcaggcagaggccatcatggtaagagggcagggggacccagggcccagc
ctcacaggctctccgtggcctggaactgcagccccagctgcatcctacacccccaccccg
aggtccccgcggttcattgggcggaggcagagcctcatcgaggacgcccgcaaggagcgg
gaggcggcggtggcagcagcggctgctgcagcccccttggagcccggggaccccctggag
gccatggcctttgaggagaaggaagggaaggccgtgctaaacctgctcttctccctgagg
gccaccaagccctcggcgctgtcccgagctgtgaaggtgttggagacgtttgaagccaaa
attcaccacctagagacccggcccgcccagaggccgcgagccgggggcccccacctggag
tacttcgtgcgcctcgaggtgccccgaggggacctgtccgccctgctcagtggtgtgcgc
caggtgtcagaggacgtgcgcagccccgcggggcccaaggtcccctggttcccaagaaaa
gtgtcagagctggacaagtgtcatcacctggtcaccaagtttgaccctgacctggacttg
gaccacccgggcttctcggaccaggtgtaccgccagcgcaggaagctgattgctgagatc
gccttccagtacaggcatggcgacccgattccccgtgtggagtacaccgccgaggagatt
gccacctggaaggaggtctacaccacgctgaagggcctctacgccacgcacgcctgcggg
gagcacctggaggcctttgctctgctggagcgcttcagcggctaccgggaagacaatatc
ccccagctggaggacgtctcccgcttcctgaaggagcgcacgggcttccagctgcggcct
gtggccggcctgctatccgcccgggacttcctggccagcctggccttccgcgtgttccag
tgcacccagtatatccgccacgcgtcctcgcccatgcactcccctgagccggactgctgc
cacgagctgctggggcacgtgcccatgctggcagaccgcaccttcgcgcagttctcacag
gacattggcctggcatccctgggggcctcggatgaggaaattgagaagctgtccacgctg
tactggttcacggtggagtttgggctgtgcaagcagaatggggaggtgaaggcctacggc
gccgggctgctgtcctcctacggggagctcctgcactgcctgtctgaggagcccgagatt
cgggccttcgaccctgaagctgcggccgtgcagccctaccaagaccagacataccagtca
gtctacttcgtgtctgagagcttcagtgacgccaaggacaagctcaggagctatgcctca
cgcatccagcgccccttctccgtgaagttcgacccgtacacgctggccatcgacgtgctg
gacagcccccaggccgtgcggcgctccttggagggtgtccaggacgagctggacaccctt
gcccatgcgctgagtgccattggctag
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