Homo sapiens (human): 100137049 Help Entry 100137049         CDS       T01001                                  Symbol PLA2G4B, HsT16992, cPLA2-beta Name (RefSeq) phospholipase A2 group IVB   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism hsa  Homo sapiens (human) Pathway hsa00564   Glycerophospholipid metabolism hsa00565   Ether lipid metabolism hsa00590   Arachidonic acid metabolism hsa00591   Linoleic acid metabolism hsa00592   alpha-Linolenic acid metabolism hsa01100   Metabolic pathways hsa04010   MAPK signaling pathway hsa04014   Ras signaling pathway hsa04072   Phospholipase D signaling pathway hsa04217   Necroptosis hsa04270   Vascular smooth muscle contraction hsa04370   VEGF signaling pathway hsa04611   Platelet activation hsa04664   Fc epsilon RI signaling pathway hsa04666   Fc gamma R-mediated phagocytosis hsa04724   Glutamatergic synapse hsa04726   Serotonergic synapse hsa04730   Long-term depression hsa04750   Inflammatory mediator regulation of TRP channels hsa04912   GnRH signaling pathway hsa04913   Ovarian steroidogenesis hsa04921   Oxytocin signaling pathway hsa05231   Choline metabolism in cancer Network nt06544  Neuroactive ligand signaling   Element N01900   Serotonin-HTR2-GNAQ/11 signaling pathway Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     100137049 (PLA2G4B)    00565 Ether lipid metabolism     100137049 (PLA2G4B)    00590 Arachidonic acid metabolism     100137049 (PLA2G4B)    00591 Linoleic acid metabolism     100137049 (PLA2G4B)    00592 alpha-Linolenic acid metabolism     100137049 (PLA2G4B)  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     100137049 (PLA2G4B)    04072 Phospholipase D signaling pathway     100137049 (PLA2G4B)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100137049 (PLA2G4B)    04664 Fc epsilon RI signaling pathway     100137049 (PLA2G4B)    04666 Fc gamma R-mediated phagocytosis     100137049 (PLA2G4B)   09152 Endocrine system    04913 Ovarian steroidogenesis     100137049 (PLA2G4B)    04921 Oxytocin signaling pathway     100137049 (PLA2G4B)   09156 Nervous system    04724 Glutamatergic synapse     100137049 (PLA2G4B)    04726 Serotonergic synapse     100137049 (PLA2G4B)    04730 Long-term depression     100137049 (PLA2G4B)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100137049 (PLA2G4B)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     100137049 (PLA2G4B) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      100137049 (PLA2G4B) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PLA2_B cPLA2_C2 C2 Motif Other DBs NCBI-GeneID:  100137049 NCBI-ProteinID:  NP_001108105 OMIM:  606088 HGNC:  9036 Ensembl:  ENSG00000243708 UniProt:  P0C869 LinkDB All DBs Position 15:41838847..41848143 Genome browser AA seq 781 aa AA seqDB search MAVAEVSRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVW NQSFHFRIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEG RLEVEFRLQSLADRGEWLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQLVVPGSCEGP QEASVGTGTFRFHCPACWEQELSIRLQDAPEEQLKAPLSALPSGQVVRLVFPTSQEPLMR VELKKEAGLRELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIM ATGGGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTE LLKTQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALINEALLHDEPHDHKLS DQREALSHGQNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEF FMGQLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQFWDRWVRNQANLDKEQVPL LKIEEPPSTAGRIAEFFTDLLTWRPLAQATHNFLRGLHFHKDYFQHPHFSTWKATTLDGL PNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDLILSLDYNLHGAFQQLQLLGRFCQE QGIPFPPISPSPEEQLQPRECHTFSDPTCPGAPAVLHFPLVSDSFREYSAPGVRRTPEEA AAGEVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYNVCNNQEQLLEALRQAVQRRRQRRP H NT seq 2346 nt NT seq  +upstreamnt  +downstreamnt atggctgtggcagaggtgtccaggacctgcctgctcacggttcgtgtcctgcaggcccat cgcctaccctctaaggacctagtgaccccctctgactgctacgtgactctctggctgccc acggcctgcagccacaggctccagacacgcacggtcaagaacagcagtagccctgtctgg aaccagagctttcacttcaggatccacaggcagctcaagaatgtcatggaactgaaagtc tttgaccaggacctggtgaccggagatgaccctgtgttgtcagtactgtttgatgcgggg actctgcgggctggggagttccggcgcgagagcttctcactgagccctcagggtgagggg cgcctggaagttgaatttcgcctgcagagtctggctgaccgtggcgagtggctcgtcagc aatggcgttctggtggcccgggagctctcctgcttgcacgttcaactggaggagacagga gaccagaagtcctcagagcacagagttcagcttgtggttcctgggtcctgtgagggtccg caggaggcctctgtgggcactggcaccttccgcttccactgcccagcctgctgggagcag gagctgagtattcgcctgcaggatgcccccgaggagcaactaaaggcgccactgagtgcc ctgccctctggtcaagtggtgaggcttgtcttccccacgtcccaggagcccctgatgaga gtggagctgaaaaaagaagcaggactgagggagctggccgtgcgactgggcttcgggccc tgtgcagaggagcaggccttcctgagcaggaggaagcaggtggtggccgcggccttgagg caggccctgcagctggacggagacctgcaggaggatgagatcccagtggtagctattatg gccactggtggtgggatccgggcaatgacttccctgtatgggcagctggctggcctgaag gagctgggcctcttggattgcgtctcctacatcaccggggcctcgggctccacctgggcc ttggccaacctttatgaggacccagagtggtctcagaaggacctggcagggcccactgag ttgctgaagacccaggtgaccaagaacaagctgggtgtgctggcccccagccagctgcag cggtaccggcaggagctggccgagcgtgcccgcttgggctacccaagctgcttcaccaac ctgtgggccctcatcaacgaggcgctgctgcatgatgagccccatgatcacaagctctca gatcaacgggaggccctgagtcatggccagaaccctctgcccatctactgtgccctcaac accaaagggcagagcctgaccacttttgaatttggggagtggtgcgagttctctccctac gaggtcggcttccccaagtacggggccttcatcccctctgagctctttggctccgagttc tttatggggcagctgatgaagaggcttcctgagtcccgcatctgcttcttagaaggtatc tggagcaacctgtatgcagccaacctccaggacagcttatactgggcctcagagcccagc cagttctgggaccgctgggtcaggaaccaggccaacctggacaaggagcaggtccccctt ctgaagatagaagaaccaccctcaacagccggcaggatagctgagtttttcaccgatctt ctgacgtggcgtccactggcccaggccacacataatttcctgcgtggcctccatttccac aaagactactttcagcatcctcacttctccacatggaaagctaccactctggatgggctc cccaaccagctgacaccctcggagccccacctgtgcctgctggatgttggctacctcatc aataccagctgcctgcccctcctgcagcccactcgggacgtggacctcatcctgtcattg gactacaacctccacggagccttccagcagttgcagctcctgggccggttctgccaggag caggggatcccgttcccacccatctcgcccagccccgaagagcagctccagcctcgggag tgccacaccttctccgaccccacctgccccggagcccctgcggtgctgcactttcctctg gtcagcgactccttccgggagtactcggcccctggggtccggcggacacccgaggaggcg gcagctggggaggtgaacctgtcttcatcggactctccctaccactacacgaaggtgacc tacagccaggaggacgtggacaagctgctgcacctgacacattacaatgtctgcaacaac caggagcagctgctggaggctctgcgccaggcagtgcagcggaggcggcagcgcaggccc cactga

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