KEGG   Homo sapiens (human): 100506658
Entry
100506658         CDS       T01001                                 
Symbol
OCLN, BLCPMG, PPP1R115, PTORCH1
Name
(RefSeq) occludin
  KO
K06088  occludin
Organism
hsa  Homo sapiens (human)
Pathway
hsa03272  Virion - Hepatitis viruses
hsa04382  Cornified envelope formation
hsa04514  Cell adhesion molecules
hsa04530  Tight junction
hsa04670  Leukocyte transendothelial migration
hsa05130  Pathogenic Escherichia coli infection
hsa05160  Hepatitis C
Network
nt06180  Pathogenic Escherichia coli
  Element
N01287  Tight junction-Actin signaling pathway
Disease
H00840  Pseudo-TORCH syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03272 Virion - Hepatitis viruses
    100506658 (OCLN)
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    100506658 (OCLN)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    100506658 (OCLN)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    100506658 (OCLN)
  09158 Development and regeneration
   04382 Cornified envelope formation
    100506658 (OCLN)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    100506658 (OCLN)
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    100506658 (OCLN)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    100506658 (OCLN)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     100506658 (OCLN)
SSDB
Motif
Pfam: Occludin_ELL MARVEL Cation_ATPase_C Laminin_II HBM FapA Knl1_RWD_C DUF4164 TMF_TATA_bd APG6_N DUF6338 Swi5 AAA_23
Other DBs
NCBI-GeneID: 100506658
NCBI-ProteinID: NP_001192183
OMIM: 602876
HGNC: 8104
Ensembl: ENSG00000197822
UniProt: Q16625 A8K3T2
Structure
LinkDB
Position
5:69492547..69558104
AA seq 522 aa
MSSRPLESPPPYRPDEFKPNHYAPSNDIYGGEMHVRPMLSQPAYSFYPEDEILHFYKWTS
PPGVIRILSMLIIVMCIAIFACVASTLAWDRGYGTSLLGGSVGYPYGGSGFGSYGSGYGY
GYGYGYGYGGYTDPRAAKGFMLAMAAFCFIAALVIFVTSVIRSEMSRTRRYYLSVIIVSA
ILGIMVFIATIVYIMGVNPTAQSSGSLYGSQIYALCNQFYTPAATGLYVDQYLYHYCVVD
PQEAIAIVLGFMIIVAFALIIFFAVKTRRKMDRYDKSNILWDKEHIYDEQPPNVEEWVKN
VSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESSYKSTPVPEVVQELPLTSPV
DDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETDYTTGGESCDELEEDWIREY
PPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAADE
YNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQKT
NT seq 1569 nt   +upstreamnt  +downstreamnt
atgtcatccaggcctcttgaaagtccacctccttacaggcctgatgaattcaaaccgaat
cattatgcaccaagcaatgacatatatggtggagagatgcatgttcgaccaatgctctct
cagccagcctactctttttacccagaagatgaaattcttcacttctacaaatggacctct
cctccaggagtgattcggatcctgtctatgctcattattgtgatgtgcattgccatcttt
gcctgtgtggcctccacgcttgcctgggacagaggctatggaacttcccttttaggaggt
agtgtaggctacccttatggaggaagtggctttggtagctacggaagtggctatggctat
ggctatggttatggctatggctacggaggctatacagacccaagagcagcaaagggcttc
atgttggccatggctgccttttgtttcattgccgcgttggtgatctttgttaccagtgtt
ataagatctgaaatgtccagaacaagaagatactacttaagtgtgataatagtgagtgct
atcctgggcatcatggtgtttattgccacaattgtctatataatgggagtgaacccaact
gctcagtcttctggatctctatatggttcacaaatatatgccctctgcaaccaattttat
acacctgcagctactggactctacgtggatcagtatttgtatcactactgtgttgtggat
ccccaggaggccattgccattgtactggggttcatgattattgtggcttttgctttaata
attttctttgctgtgaaaactcgaagaaagatggacaggtatgacaagtccaatattttg
tgggacaaggaacacatttatgatgagcagccccccaatgtcgaggagtgggttaaaaat
gtgtctgcaggcacacaggacgtgccttcacccccatctgactatgtggaaagagttgac
agtcccatggcatactcttccaatggcaaagtgaatgacaagcggttttatccagagtct
tcctataaatccacgccggttcctgaagtggttcaggagcttccattaacttcgcctgtg
gatgacttcaggcagcctcgttacagcagcggtggtaactttgagacaccttcaaaaaga
gcacctgcaaagggaagagcaggaaggtcaaagagaacagagcaagatcactatgagaca
gactacacaactggcggcgagtcctgtgatgagctggaggaggactggatcagggaatat
ccacctatcacttcagatcaacaaagacaactgtacaagaggaattttgacactggccta
caggaatacaagagcttacaatcagaacttgatgagatcaataaagaactctcccgtttg
gataaagaattggatgactatagagaagaaagtgaagagtacatggctgctgctgatgaa
tacaatagactgaagcaagtgaagggatctgcagattacaaaagtaagaagaatcattgc
aagcagttaaagagcaaattgtcacacatcaagaagatggttggagactatgatagacag
aaaacatag

KEGG   Homo sapiens (human): 9076
Entry
9076              CDS       T01001                                 
Symbol
CLDN1, CLD1, ILVASC, SEMP1
Name
(RefSeq) claudin 1
  KO
K06087  claudin
Organism
hsa  Homo sapiens (human)
Pathway
hsa03272  Virion - Hepatitis viruses
hsa04382  Cornified envelope formation
hsa04514  Cell adhesion molecules
hsa04530  Tight junction
hsa04670  Leukocyte transendothelial migration
hsa05130  Pathogenic Escherichia coli infection
hsa05160  Hepatitis C
Network
nt06180  Pathogenic Escherichia coli
  Element
N01287  Tight junction-Actin signaling pathway
Disease
H00742  Neonatal ichthyosis-sclerosing cholangitis (NISCH) syndrome
Drug target
Lixudebart: D12997
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03272 Virion - Hepatitis viruses
    9076 (CLDN1)
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    9076 (CLDN1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    9076 (CLDN1)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    9076 (CLDN1)
  09158 Development and regeneration
   04382 Cornified envelope formation
    9076 (CLDN1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    9076 (CLDN1)
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    9076 (CLDN1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    9076 (CLDN1)
   04147 Exosome [BR:hsa04147]
    9076 (CLDN1)
   04515 Cell adhesion molecules [BR:hsa04515]
    9076 (CLDN1)
Cilium and associated proteins [BR:hsa03037]
 Other cilia and associated proteins
  Stereociliary proteins
   9076 (CLDN1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of ovarian cancer cells
   9076 (CLDN1)
  Exosomal proteins of colorectal cancer cells
   9076 (CLDN1)
Cell adhesion molecules [BR:hsa04515]
 Immunoglobulin superfamily
  L1 family
   9076 (CLDN1)
SSDB
Motif
Pfam: PMP22_Claudin Claudin_2 Voltage_CLC Cytochrom_B_C SUR7 DUF2613 DUF2207_C DUF7139
Other DBs
NCBI-GeneID: 9076
NCBI-ProteinID: NP_066924
OMIM: 603718
HGNC: 2032
Ensembl: ENSG00000163347
UniProt: O95832 A5JSJ9
LinkDB
Position
3:complement(190305707..190322446)
AA seq 211 aa
MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG
QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV
IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA
LLCCSCPRKTTSYPTPRPYPKPAPSSGKDYV
NT seq 636 nt   +upstreamnt  +downstreamnt
atggccaacgcggggctgcagctgttgggcttcattctcgccttcctgggatggatcggc
gccatcgtcagcactgccctgccccagtggaggatttactcctatgccggcgacaacatc
gtgaccgcccaggccatgtacgaggggctgtggatgtcctgcgtgtcgcagagcaccggg
cagatccagtgcaaagtctttgactccttgctgaatctgagcagcacattgcaagcaacc
cgtgccttgatggtggttggcatcctcctgggagtgatagcaatctttgtggccaccgtt
ggcatgaagtgtatgaagtgcttggaagacgatgaggtgcagaagatgaggatggctgtc
attgggggtgcgatatttcttcttgcaggtctggctattttagttgccacagcatggtat
ggcaatagaatcgttcaagaattctatgaccctatgaccccagtcaatgccaggtacgaa
tttggtcaggctctcttcactggctgggctgctgcttctctctgccttctgggaggtgcc
ctactttgctgttcctgtccccgaaaaacaacctcttacccaacaccaaggccctatcca
aaacctgcaccttccagcgggaaagactacgtgtga

KEGG   Homo sapiens (human): 9075
Entry
9075              CDS       T01001                                 
Symbol
CLDN2, OAZON, claudin-2
Name
(RefSeq) claudin 2
  KO
K06087  claudin
Organism
hsa  Homo sapiens (human)
Pathway
hsa03272  Virion - Hepatitis viruses
hsa04382  Cornified envelope formation
hsa04514  Cell adhesion molecules
hsa04530  Tight junction
hsa04670  Leukocyte transendothelial migration
hsa05130  Pathogenic Escherichia coli infection
hsa05160  Hepatitis C
Network
nt06180  Pathogenic Escherichia coli
  Element
N01287  Tight junction-Actin signaling pathway
Disease
H00890  Azoospermia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03272 Virion - Hepatitis viruses
    9075 (CLDN2)
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    9075 (CLDN2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    9075 (CLDN2)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    9075 (CLDN2)
  09158 Development and regeneration
   04382 Cornified envelope formation
    9075 (CLDN2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    9075 (CLDN2)
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    9075 (CLDN2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    9075 (CLDN2)
   04147 Exosome [BR:hsa04147]
    9075 (CLDN2)
   04515 Cell adhesion molecules [BR:hsa04515]
    9075 (CLDN2)
Cilium and associated proteins [BR:hsa03037]
 Other cilia and associated proteins
  Stereociliary proteins
   9075 (CLDN2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of ovarian cancer cells
   9075 (CLDN2)
  Exosomal proteins of colorectal cancer cells
   9075 (CLDN2)
Cell adhesion molecules [BR:hsa04515]
 Immunoglobulin superfamily
  L1 family
   9075 (CLDN2)
SSDB
Motif
Pfam: PMP22_Claudin Claudin_2 Amastin TMEM164 DUF5692 Clc-like DUF5413
Other DBs
NCBI-GeneID: 9075
NCBI-ProteinID: NP_001164563
OMIM: 300520
HGNC: 2041
Ensembl: ENSG00000165376
UniProt: P57739
Structure
LinkDB
Position
X:106900164..106930861
AA seq 230 aa
MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG
ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVA
GGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGII
LCFSCSSQRNRSNYYDAYQAQPLATRSSPRPGQPPKVKSEFNSYSLTGYV
NT seq 693 nt   +upstreamnt  +downstreamnt
atggcctctcttggcctccaacttgtgggctacatcctaggccttctggggcttttgggc
acactggttgccatgctgctccccagctggaaaacaagttcttatgtcggtgccagcatt
gtgacagcagttggcttctccaagggcctctggatggaatgtgccacacacagcacaggc
atcacccagtgtgacatctatagcacccttctgggcctgcccgctgacatccaggctgcc
caggccatgatggtgacatccagtgcaatctcctccctggcctgcattatctctgtggtg
ggcatgagatgcacagtcttctgccaggaatcccgagccaaagacagagtggcggtagca
ggtggagtctttttcatccttggaggcctcctgggattcattcctgttgcctggaatctt
catgggatcctacgggacttctactcaccactggtgcctgacagcatgaaatttgagatt
ggagaggctctttacttgggcattatttcttccctgttctccctgatagctggaatcatc
ctctgcttttcctgctcatcccagagaaatcgctccaactactacgatgcctaccaagcc
caacctcttgccacaaggagctctccaaggcctggtcaacctcccaaagtcaagagtgag
ttcaattcctacagcctgacagggtatgtgtga

KEGG   Homo sapiens (human): 1365
Entry
1365              CDS       T01001                                 
Symbol
CLDN3, C7orf1, CPE-R2, CPETR2, HRVP1, RVP1
Name
(RefSeq) claudin 3
  KO
K06087  claudin
Organism
hsa  Homo sapiens (human)
Pathway
hsa03272  Virion - Hepatitis viruses
hsa04382  Cornified envelope formation
hsa04514  Cell adhesion molecules
hsa04530  Tight junction
hsa04670  Leukocyte transendothelial migration
hsa05130  Pathogenic Escherichia coli infection
hsa05160  Hepatitis C
Network
nt06180  Pathogenic Escherichia coli
  Element
N01287  Tight junction-Actin signaling pathway
Disease
H01439  Williams-Beuren syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03272 Virion - Hepatitis viruses
    1365 (CLDN3)
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    1365 (CLDN3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    1365 (CLDN3)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    1365 (CLDN3)
  09158 Development and regeneration
   04382 Cornified envelope formation
    1365 (CLDN3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    1365 (CLDN3)
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    1365 (CLDN3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    1365 (CLDN3)
   04147 Exosome [BR:hsa04147]
    1365 (CLDN3)
   04515 Cell adhesion molecules [BR:hsa04515]
    1365 (CLDN3)
Cilium and associated proteins [BR:hsa03037]
 Other cilia and associated proteins
  Stereociliary proteins
   1365 (CLDN3)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of ovarian cancer cells
   1365 (CLDN3)
  Exosomal proteins of colorectal cancer cells
   1365 (CLDN3)
Cell adhesion molecules [BR:hsa04515]
 Immunoglobulin superfamily
  L1 family
   1365 (CLDN3)
SSDB
Motif
Pfam: PMP22_Claudin Claudin_2
Other DBs
NCBI-GeneID: 1365
NCBI-ProteinID: NP_001297
OMIM: 602910
HGNC: 2045
Ensembl: ENSG00000165215
UniProt: O15551 Q75L79
LinkDB
Position
7:complement(73768997..73770270)
AA seq 220 aa
MSMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQ
MQCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVA
GVLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALL
CCSCPPREKKYTATKVVYSAPRSTGPGASLGTGYDRKDYV
NT seq 663 nt   +upstreamnt  +downstreamnt
atgtccatgggcctggagatcacgggcaccgcgctggccgtgctgggctggctgggcacc
atcgtgtgctgcgcgttgcccatgtggcgcgtgtcggccttcatcggcagcaacatcatc
acgtcgcagaacatctgggagggcctgtggatgaactgcgtggtgcagagcaccggccag
atgcagtgcaaggtgtacgactcgctgctggcactgccacaggaccttcaggcggcccgc
gccctcatcgtggtggccatcctgctggccgccttcgggctgctagtggcgctggtgggc
gcccagtgcaccaactgcgtgcaggacgacacggccaaggccaagatcaccatcgtggca
ggcgtgctgttccttctcgccgccctgctcaccctcgtgccggtgtcctggtcggccaac
accattatccgggacttctacaaccccgtggtgcccgaggcgcagaagcgcgagatgggc
gcgggcctgtacgtgggctgggcggccgcggcgctgcagctgctggggggcgcgctgctc
tgctgctcgtgtcccccacgcgagaagaagtacacggccaccaaggtcgtctactccgcg
ccgcgctccaccggcccgggagccagcctgggcacaggctacgaccgcaaggactacgtc
taa

KEGG   Homo sapiens (human): 1364
Entry
1364              CDS       T01001                                 
Symbol
CLDN4, CPE-R, CPER, CPETR, CPETR1, WBSCR8, hCPE-R
Name
(RefSeq) claudin 4
  KO
K06087  claudin
Organism
hsa  Homo sapiens (human)
Pathway
hsa03272  Virion - Hepatitis viruses
hsa04382  Cornified envelope formation
hsa04514  Cell adhesion molecules
hsa04530  Tight junction
hsa04670  Leukocyte transendothelial migration
hsa05130  Pathogenic Escherichia coli infection
hsa05160  Hepatitis C
Network
nt06180  Pathogenic Escherichia coli
  Element
N01287  Tight junction-Actin signaling pathway
Disease
H01439  Williams-Beuren syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03272 Virion - Hepatitis viruses
    1364 (CLDN4)
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    1364 (CLDN4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    1364 (CLDN4)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    1364 (CLDN4)
  09158 Development and regeneration
   04382 Cornified envelope formation
    1364 (CLDN4)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    1364 (CLDN4)
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    1364 (CLDN4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    1364 (CLDN4)
   04147 Exosome [BR:hsa04147]
    1364 (CLDN4)
   04515 Cell adhesion molecules [BR:hsa04515]
    1364 (CLDN4)
Cilium and associated proteins [BR:hsa03037]
 Other cilia and associated proteins
  Stereociliary proteins
   1364 (CLDN4)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of ovarian cancer cells
   1364 (CLDN4)
  Exosomal proteins of colorectal cancer cells
   1364 (CLDN4)
Cell adhesion molecules [BR:hsa04515]
 Immunoglobulin superfamily
  L1 family
   1364 (CLDN4)
SSDB
Motif
Pfam: PMP22_Claudin Claudin_2 TMEM_230_134 TMEM37 DUF4131
Other DBs
NCBI-GeneID: 1364
NCBI-ProteinID: NP_001296
OMIM: 602909
HGNC: 2046
Ensembl: ENSG00000189143
UniProt: O14493 Q75L80
Structure
LinkDB
Position
7:73830996..73832690
AA seq 209 aa
MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG
QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIV
AGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGL
LCCNCPPRTDKPYSAKYSAARSAAASNYV
NT seq 630 nt   +upstreamnt  +downstreamnt
atggcctccatggggctacaggtaatgggcatcgcgctggccgtcctgggctggctggcc
gtcatgctgtgctgcgcgctgcccatgtggcgcgtgacggccttcatcggcagcaacatt
gtcacctcgcagaccatctgggagggcctatggatgaactgcgtggtgcagagcaccggc
cagatgcagtgcaaggtgtacgactcgctgctggcactgccgcaggacctgcaggcggcc
cgcgccctcgtcatcatcagcatcatcgtggctgctctgggcgtgctgctgtccgtggtg
gggggcaagtgtaccaactgcctggaggatgaaagcgccaaggccaagaccatgatcgtg
gcgggcgtggtgttcctgttggccggccttatggtgatagtgccggtgtcctggacggcc
cacaacatcatccaagacttctacaatccgctggtggcctccgggcagaagcgggagatg
ggtgcctcgctctacgtcggctgggccgcctccggcctgctgctccttggcggggggctg
ctttgctgcaactgtccaccccgcacagacaagccttactccgccaagtattctgctgcc
cgctctgctgctgccagcaactacgtgtaa

KEGG   Homo sapiens (human): 7122
Entry
7122              CDS       T01001                                 
Symbol
CLDN5, AWAL, BEC1, CPETRL1, TMDVCF, TMVCF
Name
(RefSeq) claudin 5
  KO
K06087  claudin
Organism
hsa  Homo sapiens (human)
Pathway
hsa03272  Virion - Hepatitis viruses
hsa04382  Cornified envelope formation
hsa04514  Cell adhesion molecules
hsa04530  Tight junction
hsa04670  Leukocyte transendothelial migration
hsa05130  Pathogenic Escherichia coli infection
hsa05160  Hepatitis C
Network
nt06180  Pathogenic Escherichia coli
  Element
N01287  Tight junction-Actin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03272 Virion - Hepatitis viruses
    7122 (CLDN5)
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    7122 (CLDN5)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    7122 (CLDN5)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    7122 (CLDN5)
  09158 Development and regeneration
   04382 Cornified envelope formation
    7122 (CLDN5)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    7122 (CLDN5)
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    7122 (CLDN5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    7122 (CLDN5)
   04147 Exosome [BR:hsa04147]
    7122 (CLDN5)
   04515 Cell adhesion molecules [BR:hsa04515]
    7122 (CLDN5)
Cilium and associated proteins [BR:hsa03037]
 Other cilia and associated proteins
  Stereociliary proteins
   7122 (CLDN5)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of ovarian cancer cells
   7122 (CLDN5)
  Exosomal proteins of colorectal cancer cells
   7122 (CLDN5)
Cell adhesion molecules [BR:hsa04515]
 Immunoglobulin superfamily
  L1 family
   7122 (CLDN5)
SSDB
Motif
Pfam: PMP22_Claudin Claudin_2 Clc-like
Other DBs
NCBI-GeneID: 7122
NCBI-ProteinID: NP_001124333
OMIM: 602101
HGNC: 2047
Ensembl: ENSG00000184113
UniProt: O00501 D3DX19
LinkDB
Position
22:complement(19523024..19525337)
AA seq 303 aa
MTRARIGCFGPGGRARGTESAPEPSKRVPPGRSWQTQEVRQTRGANGLGPRAGSAGAKAP
GPAQGAAQHGLGGSAGLRVRVSPLAMGSAALEILGLVLCLVGWGGLILACGLPMWQVTAF
LDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYDSVLALSTEVQAARALTVSAVLLAFVAL
FVTLAGAQCTTCVAPGPAKARVALTGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVS
QKYELGAALYIGWAATALLMVGGCLLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDYDKK
NYV
NT seq 912 nt   +upstreamnt  +downstreamnt
atgacccgcgcacggattggctgcttcgggccggggggccgggcccgggggacagaatcc
gcccccgaaccttcaaagagggtaccccccggcaggagctggcagacccaggaggtgcga
cagacccgcggggcaaacggactggggccaagagccgggagcgcgggcgcaaaggcacca
gggcccgcccagggcgccgcgcagcacggccttgggggttctgcgggccttcgggtgcgc
gtctcgcctctagccatggggtccgcagcgttggagatcctgggcctggtgctgtgcctg
gtgggctgggggggtctgatcctggcgtgcgggctgcccatgtggcaggtgaccgccttc
ctggaccacaacatcgtgacggcgcagaccacctggaaggggctgtggatgtcgtgcgtg
gtgcagagcaccgggcacatgcagtgcaaagtgtacgactcggtgctggctctgagcacc
gaggtgcaggcggcgcgggcgctcaccgtgagcgccgtgctgctggcgttcgttgcgctc
ttcgtgaccctggcgggcgcgcagtgcaccacctgcgtggccccgggcccggccaaggcg
cgtgtggccctcacgggaggcgtgctctacctgttttgcgggctgctggcgctcgtgcca
ctctgctggttcgccaacattgtcgtccgcgagttttacgacccgtctgtgcccgtgtcg
cagaagtacgagctgggcgcagcgctgtacatcggctgggcggccaccgcgctgctcatg
gtaggcggctgcctcttgtgctgcggcgcctgggtctgcaccggccgtcccgacctcagc
ttccccgtgaagtactcagcgccgcggcggcccacggccaccggcgactacgacaagaag
aactacgtctga

KEGG   Homo sapiens (human): 9074
Entry
9074              CDS       T01001                                 
Symbol
CLDN6
Name
(RefSeq) claudin 6
  KO
K06087  claudin
Organism
hsa  Homo sapiens (human)
Pathway
hsa03272  Virion - Hepatitis viruses
hsa04382  Cornified envelope formation
hsa04514  Cell adhesion molecules
hsa04530  Tight junction
hsa04670  Leukocyte transendothelial migration
hsa05130  Pathogenic Escherichia coli infection
hsa05160  Hepatitis C
Network
nt06180  Pathogenic Escherichia coli
  Element
N01287  Tight junction-Actin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03272 Virion - Hepatitis viruses
    9074 (CLDN6)
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    9074 (CLDN6)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    9074 (CLDN6)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    9074 (CLDN6)
  09158 Development and regeneration
   04382 Cornified envelope formation
    9074 (CLDN6)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    9074 (CLDN6)
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    9074 (CLDN6)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    9074 (CLDN6)
   04147 Exosome [BR:hsa04147]
    9074 (CLDN6)
   04515 Cell adhesion molecules [BR:hsa04515]
    9074 (CLDN6)
Cilium and associated proteins [BR:hsa03037]
 Other cilia and associated proteins
  Stereociliary proteins
   9074 (CLDN6)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of ovarian cancer cells
   9074 (CLDN6)
  Exosomal proteins of colorectal cancer cells
   9074 (CLDN6)
Cell adhesion molecules [BR:hsa04515]
 Immunoglobulin superfamily
  L1 family
   9074 (CLDN6)
SSDB
Motif
Pfam: PMP22_Claudin Claudin_2 GPDPase_memb
Other DBs
NCBI-GeneID: 9074
NCBI-ProteinID: NP_067018
OMIM: 615798
HGNC: 2048
Ensembl: ENSG00000184697
UniProt: P56747
LinkDB
Position
16:complement(3014712..3018183)
AA seq 220 aa
MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG
QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLT
SGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGL
LCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEYPTKNYV
NT seq 663 nt   +upstreamnt  +downstreamnt
atggcctctgccggaatgcagatcctgggagtcgtcctgacactgctgggctgggtgaat
ggcctggtctcctgtgccctgcccatgtggaaggtgaccgctttcatcggcaacagcatc
gtggtggcccaggtggtgtgggagggcctgtggatgtcctgcgtggtgcagagcaccggc
cagatgcagtgcaaggtgtacgactcactgctggcgctgccacaggacctgcaggctgca
cgtgccctctgtgtcatcgccctccttgtggccctgttcggcttgctggtctaccttgct
ggggccaagtgtaccacctgtgtggaggagaaggattccaaggcccgcctggtgctcacc
tctgggattgtctttgtcatctcaggggtcctgacgctaatccccgtgtgctggacggcg
catgccatcatccgggacttctataaccccctggtggctgaggcccaaaagcgggagctg
ggggcctccctctacttgggctgggcggcctcaggccttttgttgctgggtggggggttg
ctgtgctgcacttgcccctcgggggggtcccagggccccagccattacatggcccgctac
tcaacatctgcccctgccatctctcgggggccctctgagtaccctaccaagaattacgtc
tga

KEGG   Homo sapiens (human): 1366
Entry
1366              CDS       T01001                                 
Symbol
CLDN7, CEPTRL2, CLDN-7, CPETRL2, Hs.84359, claudin-1
Name
(RefSeq) claudin 7
  KO
K06087  claudin
Organism
hsa  Homo sapiens (human)
Pathway
hsa03272  Virion - Hepatitis viruses
hsa04382  Cornified envelope formation
hsa04514  Cell adhesion molecules
hsa04530  Tight junction
hsa04670  Leukocyte transendothelial migration
hsa05130  Pathogenic Escherichia coli infection
hsa05160  Hepatitis C
Network
nt06180  Pathogenic Escherichia coli
  Element
N01287  Tight junction-Actin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03272 Virion - Hepatitis viruses
    1366 (CLDN7)
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    1366 (CLDN7)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    1366 (CLDN7)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    1366 (CLDN7)
  09158 Development and regeneration
   04382 Cornified envelope formation
    1366 (CLDN7)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    1366 (CLDN7)
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    1366 (CLDN7)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    1366 (CLDN7)
   04147 Exosome [BR:hsa04147]
    1366 (CLDN7)
   04515 Cell adhesion molecules [BR:hsa04515]
    1366 (CLDN7)
Cilium and associated proteins [BR:hsa03037]
 Other cilia and associated proteins
  Stereociliary proteins
   1366 (CLDN7)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of ovarian cancer cells
   1366 (CLDN7)
  Exosomal proteins of colorectal cancer cells
   1366 (CLDN7)
Cell adhesion molecules [BR:hsa04515]
 Immunoglobulin superfamily
  L1 family
   1366 (CLDN7)
SSDB
Motif
Pfam: PMP22_Claudin Claudin_2 Clc-like OppC_N
Other DBs
NCBI-GeneID: 1366
NCBI-ProteinID: NP_001171951
OMIM: 609131
HGNC: 2049
Ensembl: ENSG00000181885
UniProt: O95471 A0A384ME58
LinkDB
Position
17:complement(7259903..7263213)
AA seq 211 aa
MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG
MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM
GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA
LLSCSCPGNESKAGYRVPRSYPKSNSSKEYV
NT seq 636 nt   +upstreamnt  +downstreamnt
atggccaattcgggcctgcagttgctgggcttctccatggccctgctgggctgggtgggt
ctggtggcctgcaccgccatcccgcagtggcagatgagctcctatgcgggtgacaacatc
atcacggcccaggccatgtacaaggggctgtggatggactgcgtcacgcagagcacgggg
atgatgagctgcaaaatgtacgactcggtgctcgccctgtccgcggccttgcaggccact
cgagccctaatggtggtctccctggtgctgggcttcctggccatgtttgtggccacgatg
ggcatgaagtgcacgcgctgtgggggagacgacaaagtgaagaaggcccgtatagccatg
ggtggaggcataattttcatcgtggcaggtcttgccgccttggtagcttgctcctggtat
ggccatcagattgtcacagacttttataaccctttgatccctaccaacattaagtatgag
tttggccctgccatctttattggctgggcagggtctgccctagtcatcctgggaggtgca
ctgctctcctgttcctgtcctgggaatgagagcaaggctgggtaccgtgtaccccgctct
taccctaagtccaactcttccaaggagtatgtgtga

KEGG   Homo sapiens (human): 9073
Entry
9073              CDS       T01001                                 
Symbol
CLDN8, HEL-S-79
Name
(RefSeq) claudin 8
  KO
K06087  claudin
Organism
hsa  Homo sapiens (human)
Pathway
hsa03272  Virion - Hepatitis viruses
hsa04382  Cornified envelope formation
hsa04514  Cell adhesion molecules
hsa04530  Tight junction
hsa04670  Leukocyte transendothelial migration
hsa05130  Pathogenic Escherichia coli infection
hsa05160  Hepatitis C
Network
nt06180  Pathogenic Escherichia coli
  Element
N01287  Tight junction-Actin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03272 Virion - Hepatitis viruses
    9073 (CLDN8)
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    9073 (CLDN8)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    9073 (CLDN8)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    9073 (CLDN8)
  09158 Development and regeneration
   04382 Cornified envelope formation
    9073 (CLDN8)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    9073 (CLDN8)
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    9073 (CLDN8)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    9073 (CLDN8)
   04147 Exosome [BR:hsa04147]
    9073 (CLDN8)
   04515 Cell adhesion molecules [BR:hsa04515]
    9073 (CLDN8)
Cilium and associated proteins [BR:hsa03037]
 Other cilia and associated proteins
  Stereociliary proteins
   9073 (CLDN8)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of ovarian cancer cells
   9073 (CLDN8)
  Exosomal proteins of colorectal cancer cells
   9073 (CLDN8)
Cell adhesion molecules [BR:hsa04515]
 Immunoglobulin superfamily
  L1 family
   9073 (CLDN8)
SSDB
Motif
Pfam: PMP22_Claudin Claudin_2
Other DBs
NCBI-GeneID: 9073
NCBI-ProteinID: NP_955360
OMIM: 611231
HGNC: 2050
Ensembl: ENSG00000156284
UniProt: P56748 A0A0K0K1I9
LinkDB
Position
21:complement(30214006..30216097)
AA seq 225 aa
MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI
RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL
TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA
LFCCVFCCNEKSSSYRYSIPSHRTTQKSYHTGKKSPSVYSRSQYV
NT seq 678 nt   +upstreamnt  +downstreamnt
atggcaacccatgccttagaaatcgctgggctgtttcttggtggtgttggaatggtgggc
acagtggctgtcactgtcatgcctcagtggagagtgtcggccttcattgaaaacaacatc
gtggtttttgaaaacttctgggaaggactgtggatgaattgcgtgaggcaggctaacatc
aggatgcagtgcaaaatctatgattccctgctggctctttctccggacctacaggcagcc
agaggactgatgtgtgctgcttccgtgatgtccttcttggctttcatgatggccatcctt
ggcatgaaatgcaccaggtgcacgggggacaatgagaaggtgaaggctcacattctgctg
acggctggaatcatcttcatcatcacgggcatggtggtgctcatccctgtgagctgggtt
gccaatgccatcatcagagatttctataactcaatagtgaatgttgcccaaaaacgtgag
cttggagaagctctctacttaggatggaccacggcactggtgctgattgttggaggagct
ctgttctgctgcgttttttgttgcaacgaaaagagcagtagctacagatactcgatacct
tcccatcgcacaacccaaaaaagttatcacaccggaaagaagtcaccgagcgtctactcc
agaagtcagtatgtgtag

KEGG   Homo sapiens (human): 9080
Entry
9080              CDS       T01001                                 
Symbol
CLDN9, DFNB116
Name
(RefSeq) claudin 9
  KO
K06087  claudin
Organism
hsa  Homo sapiens (human)
Pathway
hsa03272  Virion - Hepatitis viruses
hsa04382  Cornified envelope formation
hsa04514  Cell adhesion molecules
hsa04530  Tight junction
hsa04670  Leukocyte transendothelial migration
hsa05130  Pathogenic Escherichia coli infection
hsa05160  Hepatitis C
Network
nt06180  Pathogenic Escherichia coli
  Element
N01287  Tight junction-Actin signaling pathway
Disease
H00605  Deafness, autosomal recessive
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03272 Virion - Hepatitis viruses
    9080 (CLDN9)
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    9080 (CLDN9)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    9080 (CLDN9)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    9080 (CLDN9)
  09158 Development and regeneration
   04382 Cornified envelope formation
    9080 (CLDN9)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    9080 (CLDN9)
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    9080 (CLDN9)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    9080 (CLDN9)
   04147 Exosome [BR:hsa04147]
    9080 (CLDN9)
   04515 Cell adhesion molecules [BR:hsa04515]
    9080 (CLDN9)
Cilium and associated proteins [BR:hsa03037]
 Other cilia and associated proteins
  Stereociliary proteins
   9080 (CLDN9)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of ovarian cancer cells
   9080 (CLDN9)
  Exosomal proteins of colorectal cancer cells
   9080 (CLDN9)
Cell adhesion molecules [BR:hsa04515]
 Immunoglobulin superfamily
  L1 family
   9080 (CLDN9)
SSDB
Motif
Pfam: PMP22_Claudin Claudin_2 TMEM_230_134 DUF7139
Other DBs
NCBI-GeneID: 9080
NCBI-ProteinID: NP_066192
OMIM: 615799
HGNC: 2051
Ensembl: ENSG00000213937
UniProt: O95484
Structure
LinkDB
Position
16:3012923..3014505
AA seq 217 aa
MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG
QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLT
AGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGL
LCCTCPPPQVERPRGPRLGYSIPSRSGASGLDKRDYV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggcttcgaccggcttagaactgctgggcatgaccctggctgtgctgggctggctgggg
accctggtgtcctgcgccctgcccctgtggaaggtgaccgccttcatcggcaacagcatc
gtggtggcccaggtggtgtgggagggcctgtggatgtcctgcgtggtgcagagcacgggc
cagatgcagtgcaaggtgtacgactcactgctggctctgccgcaggacctgcaggccgca
cgtgccctctgtgtcattgccctcctgctggccctgcttggcctcctggtggccatcaca
ggtgcccagtgtaccacgtgtgtggaggacgaaggtgccaaggcccgtatcgtgctcacc
gcgggggtcatcctcctcctcgccggcatcctggtgctcatccctgtgtgctggacggcg
cacgccatcatccaggacttctacaaccccctggtggctgaggccctcaagcgggagctg
ggggcctccctctacctgggctgggcggcggctgcactgcttatgctgggcggggggctc
ctctgctgcacgtgccccccgccccaggtcgagcggccccgcggacctcggctgggctac
tccatcccctcccgctcgggtgcatctggactggacaagagggactacgtgtga

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