NETWORK: N01287
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Entry
N01287 Network
Name
Tight junction-Actin signaling pathway
Definition
(OCLN,
CLDN) == TJP1 == CTTN == ARP2/3 == (ACTB,
ACTG1)
Expanded
(100506658,
(9076,
9075,
1365,
1364,
7122,
9074,
1366,
9073,
9080,
9071,
5010,
23562,
24146,
10686,
26285,
51208,
149461,
49861,
53842,
137075,
100132463,
644672,
100288814)) == 7082 == 2017 == (10097+10096+10552+10095+10109+10094+10093+10092+81873) == (60,
71)
Class
nt06180
Pathogenic Escherichia coli
Type
Reference
Pathway
hsa04530
Tight junction
Gene
100506658
OCLN; occludin
9076
CLDN1; claudin 1
9075
CLDN2; claudin 2
1365
CLDN3; claudin 3
1364
CLDN4; claudin 4
7122
CLDN5; claudin 5
9074
CLDN6; claudin 6
1366
CLDN7; claudin 7
9073
CLDN8; claudin 8
9080
CLDN9; claudin 9
9071
CLDN10; claudin 10
5010
CLDN11; claudin 11
23562
CLDN14; claudin 14
24146
CLDN15; claudin 15
10686
CLDN16; claudin 16
26285
CLDN17; claudin 17
51208
CLDN18; claudin 18
149461
CLDN19; claudin 19
49861
CLDN20; claudin 20
53842
CLDN22; claudin 22
137075
CLDN23; claudin 23
100132463
CLDN24; claudin 24
644672
CLDN25; claudin 25
100288814
CLDN34; claudin 34
7082
TJP1; tight junction protein 1
2017
CTTN; cortactin
10097
ACTR2; actin related protein 2
10096
ACTR3; actin related protein 3
10552
ARPC1A; actin related protein 2/3 complex subunit 1A
10095
ARPC1B; actin related protein 2/3 complex subunit 1B
10109
ARPC2; actin related protein 2/3 complex subunit 2
10094
ARPC3; actin related protein 2/3 complex subunit 3
10093
ARPC4; actin related protein 2/3 complex subunit 4
10092
ARPC5; actin related protein 2/3 complex subunit 5
81873
ARPC5L; actin related protein 2/3 complex subunit 5 like
60
ACTB; actin beta
71
ACTG1; actin gamma 1
Reference
PMID:
28322932
Authors
Lechuga S, Ivanov AI
Title
Disruption of the epithelial barrier during intestinal inflammation: Quest for new molecules and mechanisms.
Journal
Biochim Biophys Acta Mol Cell Res 1864:1183-1194 (2017)
DOI:
10.1016/j.bbamcr.2017.03.007
Reference
PMID:
11607842
Authors
Weed SA, Parsons JT
Title
Cortactin: coupling membrane dynamics to cortical actin assembly.
Journal
Oncogene 20:6418-34 (2001)
DOI:
10.1038/sj.onc.1204783
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