KEGG   NETWORK: N01287
Entry
N01287                      Network                                

Name
Tight junction-Actin signaling pathway
Definition
(OCLN,CLDN) -- TJP1 -- CTTN -- ARP2/3 -- (ACTB,ACTG1)
  Expanded
(100506658,(9076,9075,1365,1364,7122,9074,1366,9073,9080,9071,5010,23562,24146,10686,26285,51208,149461,49861,53842,137075,100132463,644672,100288814)) -- 7082 -- 2017 -- (10097+10096+10552+10095+10109+10094+10093+10092+81873) -- (60,71)
Class
nt06135 Cytoskeletal regulation (viruses and bacteria)
Type
Reference
Pathway
hsa04530  Tight junction
Gene
100506658  OCLN; occludin
9076  CLDN1; claudin 1
9075  CLDN2; claudin 2
1365  CLDN3; claudin 3
1364  CLDN4; claudin 4
7122  CLDN5; claudin 5
9074  CLDN6; claudin 6
1366  CLDN7; claudin 7
9073  CLDN8; claudin 8
9080  CLDN9; claudin 9
9071  CLDN10; claudin 10
5010  CLDN11; claudin 11
23562  CLDN14; claudin 14
24146  CLDN15; claudin 15
10686  CLDN16; claudin 16
26285  CLDN17; claudin 17
51208  CLDN18; claudin 18
149461  CLDN19; claudin 19
49861  CLDN20; claudin 20
53842  CLDN22; claudin 22
137075  CLDN23; claudin 23
100132463  CLDN24; claudin 24
644672  CLDN25; claudin 25
100288814  CLDN34; claudin 34
7082  TJP1; tight junction protein 1
2017  CTTN; cortactin
10097  ACTR2; actin related protein 2
10096  ACTR3; actin related protein 3
10552  ARPC1A; actin related protein 2/3 complex subunit 1A
10095  ARPC1B; actin related protein 2/3 complex subunit 1B
10109  ARPC2; actin related protein 2/3 complex subunit 2
10094  ARPC3; actin related protein 2/3 complex subunit 3
10093  ARPC4; actin related protein 2/3 complex subunit 4
10092  ARPC5; actin related protein 2/3 complex subunit 5
81873  ARPC5L; actin related protein 2/3 complex subunit 5 like
60  ACTB; actin beta
71  ACTG1; actin gamma 1
Reference
  Authors
Lechuga S, Ivanov AI
  Title
Disruption of the epithelial barrier during intestinal inflammation: Quest for new molecules and mechanisms.
  Journal
Biochim Biophys Acta Mol Cell Res 1864:1183-1194 (2017)
DOI:10.1016/j.bbamcr.2017.03.007
Reference
  Authors
Weed SA, Parsons JT
  Title
Cortactin: coupling membrane dynamics to cortical actin assembly.
  Journal
Oncogene 20:6418-34 (2001)
DOI:10.1038/sj.onc.1204783
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