Homo sapiens (human): 10116
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Entry
10116 CDS
T01001
Symbol
FEM1B, F1A-ALPHA, F1AA, FEM1-beta
Name
(RefSeq) fem-1 homolog B
KO
K10349
protein fem-1 homolog B
Organism
hsa
Homo sapiens (human)
Disease
H02715
Neurodevelopmental disorder with defects of ubiquitin-proteasome system
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
hsa04121
]
10116 (FEM1B)
Ubiquitin system [BR:
hsa04121
]
Ubiquitin ligases (E3)
Multi subunit type E3
Cul2 complex
Target recognizing subunit
10116 (FEM1B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ank_2
Ank
Ank_4
Ank_3
Ank_5
Ank_KRIT1
Motif
Other DBs
NCBI-GeneID:
10116
NCBI-ProteinID:
NP_056137
OMIM:
613539
HGNC:
3649
Ensembl:
ENSG00000169018
UniProt:
Q9UK73
Structure
PDB
PDBj
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All DBs
Position
15:68277745..68295862
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AA seq
627 aa
AA seq
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MEGLAGYVYKAASEGKVLTLAALLLNRSESDIRYLLGYVSQQGGQRSTPLIIAARNGHAK
VVRLLLEHYRVQTQQTGTVRFDGYVIDGATALWCAAGAGHFEVVKLLVSHGANVNHTTVT
NSTPLRAACFDGRLDIVKYLVENNANISIANKYDNTCLMIAAYKGHTDVVRYLLEQRADP
NAKAHCGATALHFAAEAGHIDIVKELIKWRAAIVVNGHGMTPLKVAAESCKADVVELLLS
HADCDRRSRIEALELLGASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPPIH
AYGNRTECRNPQELESIRQDRDALHMEGLIVRERILGADNIDVSHPIIYRGAVYADNMEF
EQCIKLWLHALHLRQKGNRNTHKDLLRFAQVFSQMIHLNETVKAPDIECVLRCSVLEIEQ
SMNRVKNISDADVHNAMDNYECNLYTFLYLVCISTKTQCSEEDQCKINKQIYNLIHLDPR
TREGFTLLHLAVNSNTPVDDFHTNDVCSFPNALVTKLLLDCGAEVNAVDNEGNSALHIIV
QYNRPISDFLTLHSIIISLVEAGAHTDMTNKQNKTPLDKSTTGVSEILLKTQMKMSLKCL
AARAVRANDINYQDQIPRTLEEFVGFH
NT seq
1884 nt
NT seq
+upstream
nt +downstream
nt
atggagggcctggctggctatgtatacaaggcggccagcgagggcaaggtgctgactctg
gccgccttgcttctcaaccggtctgaaagcgacatccgctatctgcttggctatgtcagc
cagcagggagggcagcgctccacgcccctcatcatcgcagcccgcaatggacacgcaaag
gtggtacgcttgctcttagaacattaccgggtgcagactcagcagactggcaccgtccgc
ttcgacgggtatgtcattgatggtgccactgctctttggtgtgcagctggagcaggacat
tttgaagttgttaaacttctagtcagccatggagccaacgtgaaccataccacagtaact
aattcaacccccctgcgggcagcatgctttgatggcagactggacattgtgaaatacttg
gttgaaaataatgccaacatcagcattgccaacaaatatgacaacacctgcctaatgatt
gcggcatataagggacacactgatgtggtcagataccttttagaacaacgtgctgatccc
aatgccaaagcacattgtggagccacagcattgcactttgcagctgaagctgggcacata
gatattgtgaaagagctgataaaatggcgtgctgctatagtagtgaatggccatgggatg
acgccattgaaagtagctgccgaaagctgtaaagctgatgtcgtagaactgttactctct
catgctgattgcgaccgaagaagtcggattgaagctttggaactcttgggtgcctccttt
gcaaatgaccgtgagaactatgacatcataaagacataccactatctatatttagccatg
ttagagaggttccaagatggtgataacattctcgaaaaagaggttcttccaccaatccat
gcttatgggaatagaactgaatgtagaaatcctcaggaactggagtccattcggcaagac
agagatgctcttcatatggaaggccttatagttcgggaacggattttaggtgctgacaat
attgatgtttctcatcccatcatttacagaggagctgtttatgcggataatatggaattt
gagcagtgtatcaagttgtggcttcatgccctgcacctcagacaaaaaggtaacaggaac
acccacaaggatcttcttcgatttgctcaagttttctcacaaatgatacatttgaatgaa
actgtgaaggccccagacatagaatgtgttttgagatgcagtgttttggaaatagaacaa
agtatgaacagagtgaaaaatatttcagatgctgatgtccacaatgctatggacaattat
gaatgtaatctctatacctttctgtatttagtgtgcatctctaccaaaacacagtgcagc
gaagaagatcagtgcaaaattaacaagcagatctacaacctgattcaccttgatcccaga
actcgtgaaggtttcaccttgctgcatctggctgtcaattccaatactccagttgatgat
ttccacaccaatgacgtctgcagctttccaaatgcacttgtcacaaagctcctgctggac
tgtggtgctgaggtgaatgccgtggacaatgagggaaacagtgcccttcatattatcgtt
cagtacaacaggcccatcagtgattttttgaccttgcactccatcatcattagcctagtt
gaagccggagctcacactgacatgacgaataaacagaataagactccgctagacaaaagt
acaactggggtatctgaaatactgcttaaaactcaaatgaagatgagtctcaagtgcctg
gctgcccgagcagttcgggctaatgacattaactaccaagaccagatccccagaactctt
gaagagtttgttggatttcattaa
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