Homo sapiens (human): 10203 Help Entry 10203             CDS       T01001                                  Symbol CALCRL, CGRPR, CRLR, LMPHM8 Name (RefSeq) calcitonin receptor like receptor   KO K04577   calcitonin receptor-like Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04270   Vascular smooth muscle contraction Disease H00535   Lymphatic malformation Drug target Atogepant:  D11313<US> Davalintide (DG01352):  D09600 D09601 Erenumab:  D10928<JP/US> Rimegepant (DG01845):  D10662 D10663<US> Telcagepant (DG01353):  D09391 D09392 Ubrogepant:  D10673<US> Zavegepant (DG03122):  D11898 D11899 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     10203 (CALCRL)  09150 Organismal Systems   09153 Circulatory system    04270 Vascular smooth muscle contraction     10203 (CALCRL)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     10203 (CALCRL) G protein-coupled receptors [BR:hsa04030]  Secretin receptor family   Calcium-regulating peptide    Calcitonin     10203 (CALCRL) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  7tm_2 HRM DUF4034 Motif Other DBs NCBI-GeneID:  10203 NCBI-ProteinID:  NP_001258680 OMIM:  114190 HGNC:  16709 Ensembl:  ENSG00000064989 Vega:  OTTHUMG00000132636 Pharos:  Q16602(Tchem) UniProt:  Q16602 LinkDB All DBs Structure PDB:  3N7S 3AQF 3N7P 3N7R 6E3Y Thumbnails Position 2q32.1 AA seq 461 aa AA seqDB search MEKKCTLYFLVLLPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECYQKIMQDPIQQA EGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRT WTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNL FFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTL IVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLLYIIHGPICA ALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKI AEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSFSNSEALRSAS YTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN NT seq 1386 nt NT seq  +upstreamnt  +downstreamnt atggagaaaaagtgtaccctgtattttctggttctcttgcctttttttatgattcttgtt acagcagaattagaagagagtcctgaggactcaattcagttgggagttactagaaataaa atcatgacagctcaatatgaatgttaccaaaagattatgcaagaccccattcaacaagca gaaggcgtttactgcaacagaacctgggatggatggctctgctggaacgatgttgcagca ggaactgaatcaatgcagctctgccctgattactttcaggactttgatccatcagaaaaa gttacaaagatctgtgaccaagatggaaactggtttagacatccagcaagcaacagaaca tggacaaattatacccagtgtaatgttaacacccacgagaaagtgaagactgcactaaat ttgttttacctgaccataattggacacggattgtctattgcatcactgcttatctcgctt ggcatattcttttatttcaagagcctaagttgccaaaggattaccttacacaaaaatctg ttcttctcatttgtttgtaactctgttgtaacaatcattcacctcactgcagtggccaac aaccaggccttagtagccacaaatcctgttagttgcaaagtgtcccagttcattcatctt tacctgatgggctgtaattacttttggatgctctgtgaaggcatttacctacacacactc attgtggtggccgtgtttgcagagaagcaacatttaatgtggtattattttcttggctgg ggatttccactgattcctgcttgtatacatgccattgctagaagcttatattacaatgac aattgctggatcagttctgatacccatctcctctacattatccatggcccaatttgtgct gctttactggtgaatctttttttcttgttaaatattgtacgcgttctcatcaccaagtta aaagttacacaccaagcggaatccaatctgtacatgaaagctgtgagagctactcttatc ttggtgccattgcttggcattgaatttgtgctgattccatggcgacctgaaggaaagatt gcagaggaggtatatgactacatcatgcacatccttatgcacttccagggtcttttggtc tctaccattttctgcttctttaatggagaggttcaagcaattctgagaagaaactggaat caatacaaaatccaatttggaaacagcttttccaactcagaagctcttcgtagtgcgtct tacacagtgtcaacaatcagtgatggtccaggttatagtcatgactgtcctagtgaacac ttaaatggaaaaagcatccatgatattgaaaatgttctcttaaaaccagaaaatttatat aattga

Homo sapiens (human): 799 Help Entry 799               CDS       T01001                                  Symbol CALCR, CRT, CT-R, CTR, CTR1 Name (RefSeq) calcitonin receptor   KO K04576   calcitonin receptor Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04380   Osteoclast differentiation Disease H01593   Osteoporosis Drug target Avicatonin:  D09771 Calcitonin (salmon synthetic):  D00249<US> Davalintide (DG01352):  D09600 D09601 Elcatonin:  D03287<JP> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     799 (CALCR)  09150 Organismal Systems   09158 Development and regeneration    04380 Osteoclast differentiation     799 (CALCR)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     799 (CALCR) G protein-coupled receptors [BR:hsa04030]  Secretin receptor family   Calcium-regulating peptide    Calcitonin     799 (CALCR) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  7tm_2 HRM Motif Other DBs NCBI-GeneID:  799 NCBI-ProteinID:  NP_001158210 OMIM:  114131 HGNC:  1440 Ensembl:  ENSG00000004948 Vega:  OTTHUMG00000023599 Pharos:  P30988(Tclin) UniProt:  P30988 A0A0C4DG16 LinkDB All DBs Structure PDB:  5II0 6NIY 5UZ7 Thumbnails Position 7q21.3 AA seq 474 aa AA seqDB search MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYVVGRKKMMDAQYKCYDRMQ QLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFK HPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQR VTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCE GIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLLYI IHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFP WRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRR PSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQESSA NT seq 1425 nt NT seq  +upstreamnt  +downstreamnt atgaggttcacatttacaagccggtgcttggcactgtttcttcttctaaatcacccaacc ccaattcttcctgccttttcaaatcaaacctatccaacaatagagcccaagccatttctt tacgtcgtaggacgaaagaagatgatggatgcacagtacaaatgctatgaccgaatgcag cagttacccgcataccaaggagaaggtccatattgcaatcgcacctgggatggatggctg tgctgggatgacacaccggctggagtattgtcctatcagttctgcccagattattttccg gattttgatccatcagaaaaggttacaaaatactgtgatgaaaaaggtgtttggtttaaa catcctgaaaacaatcgaacctggtccaactatactatgtgcaatgctttcactcctgag aaactgaagaatgcatatgttctgtactatttggctattgtgggtcattctttgtcaatt ttcaccctagtgatttccctggggattttcgtgtttttcaggagccttggctgccaaagg gtaaccctgcacaagaacatgtttcttacttacattctgaattctatgattatcatcatc cacctggttgaagtagtacccaatggagagctcgtgcgaagggacccggtgagctgcaag attttgcattttttccaccagtacatgatggcctgcaactatttctggatgctctgtgaa gggatctatcttcatacactcattgtcgtggctgtgtttactgagaagcaacgcttgcgg tggtattatctcttgggctgggggttcccgctggtgccaaccactatccatgctattacc agggccgtgtacttcaatgacaactgctggctgagtgtggaaacccatttgctttacata atccatggacctgtcatggcggcacttgtggtcaatttcttctttttgctcaacattgtc cgggtgcttgtgaccaaaatgagggaaacccatgaggcggaatcccacatgtacctgaag gctgtgaaggccaccatgatccttgtgcccctgctgggaatccagtttgtcgtctttccc tggagaccttccaacaagatgcttgggaagatatatgattacgtgatgcactctctgatt catttccagggcttctttgttgcgaccatctactgcttctgcaacaatgaggtccaaacc accgtgaagcgccaatgggcccaattcaaaattcagtggaaccagcgttgggggaggcgc ccctccaaccgctctgctcgcgctgcagccgctgctgcggaggctggcgacatcccaatt tacatctgccatcaggagctgaggaatgaaccagccaacaaccaaggcgaggagagtgct gagatcatccctttgaatatcatagagcaagagtcatctgcttga

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