Homo sapiens (human): 102724428 Help Entry 102724428         CDS       T01001                                  Symbol SIK, SIK-1, SIK1, SIK1B, SNF1LK Name (RefSeq) salt inducible kinase 1B (putative)   KO K19008   serine/threonine-protein kinase SIK1 [EC:2.7.11.1] Organism hsa  Homo sapiens (human) Pathway hsa04922   Glucagon signaling pathway Brite KEGG Orthology (KO) [BR:hsa00001]  09150 Organismal Systems   09152 Endocrine system    04922 Glucagon signaling pathway     102724428 (SIK)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hsa01001]     102724428 (SIK) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      102724428 (SIK) Protein kinases [BR:hsa01001]  Serine/threonine kinases: CAMK group   CAMKL family    102724428 (SIK) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr UBA_SIK3 Kinase-like Haspin_kinase UBA_BRSK ABC1 APH Motif Other DBs NCBI-GeneID:  102724428 NCBI-ProteinID:  NP_001307572 Ensembl:  ENSG00000275993 UniProt:  P57059 LinkDB All DBs Position 21:6111131..6123778 Genome browser AA seq 783 aa AA seqDB search MVIMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDK TRLDSSNLEKIYREVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGH LSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFGNFYKSGEPL STWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGR FRIPFFMSQDCESLIRRMLVVDPARRITIAQIRQHRWMRAEPCLPGPACPAFSAHSYTSN LGDYDEQALGIMQTLGVDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRNAQCARPGPAR QPRPRSSDLSGLEVPQEGLSTDPFRPALLCPQPQTLVQSVLQAEMDCELQSSLQWPLFFP VDASCSGVFRPRPVSPSSLLDTAISEEARQGPGLEEEQDTQESLPSSTGRRHTLAEVSTR LSPLTAPCIVVSPSTTASPAEGTSSDSCLTFSASKSPAGLSGTPATQGLLGACSPVRLAS PFLGSQSATPVLQAQGGLGGAVLLPVSFQEGRRASDTSLTQGLKAFRQQLRKTTRTKGFL GLNKIKGLARQVCQVPASRASRGGLSPFHAPAQSPGLHGGAAGSREGWSLLEEVLEQQRL LQLQHHPAAAPGCSQAPQPAPAPFVIAPCDGPGAAPLPSTLLTSGLPLLPPPLLQTGASP VASAAQLLDTHLHIGTGPTALPAVPPPRLARLAPGCEPLGLLQGDCEMEDLMPCSLGTFV LVQ NT seq 2352 nt NT seq  +upstreamnt  +downstreamnt atggttatcatgtcggagttcagcgcggaccccgcgggccagggtcagggccagcagaag cccctccgggtgggtttttacgacatcgagcggaccctgggcaaaggcaacttcgcggtg gtgaagctggcgcggcatcgagtcaccaaaacgcaggttgcaataaaaataattgataaa acacgattagattcaagcaatttggagaaaatctatcgtgaggttcagctgatgaagctt ctgaaccatccacacatcataaagctttaccaggttatggaaacaaaggacatgctttac atcgtcactgaatttgctaaaaatggagaaatgtttgattatttgacttccaacgggcac ctgagtgagaacgaggcgcggaagaagttctggcaaatcctgtcggccgtggagtactgt cacgaccatcacatcgtccaccgggacctcaagaccgagaacctcctgctggatggcaac atggacatcaagctggcagattttggatttgggaatttctacaagtcaggagagcctctg tccacgtggtgtgggagccccccgtatgccgccccggaagtctttgaggggaaggagtat gaaggcccccagctggacatctggagcctgggcgtggtgctgtacgtcctggtctgcggt tctctccccttcgatgggcctaacctgccgacgctgagacagcgggtgctggagggccgc ttccgcatccccttcttcatgtctcaagactgtgagagcctgatccgccgcatgctggtg gtggaccccgccaggcgcatcaccatcgcccagatccggcagcaccggtggatgcgggct gagccctgcttgccgggacccgcctgccccgccttctccgcacacagctacacctccaac ctgggcgactacgatgagcaggcgctgggtatcatgcagaccctgggcgtggaccggcag aggacggtggagtcactgcaaaacagcagctataaccactttgctgccatttattacctc ctccttgagcggctcaaggagtatcggaatgcccagtgcgcccgccccgggcctgccagg cagccgcggcctcggagctcggacctcagtggtttggaggtgcctcaggaaggtctttcc accgaccctttccgacctgccttgctgtgcccgcagccgcagaccttggtgcagtccgtc ctccaggccgagatggactgtgagctccagagctcgctgcagtggcccttgttcttcccg gtggatgccagctgcagcggagtgttccggccccggcccgtgtccccaagcagcctgctg gacacagccatcagtgaggaggccaggcaggggccgggcctagaggaggagcaggacacg caggagtccctgcccagcagcacgggccggaggcacaccctggccgaggtctccacccgc ctctccccactcaccgcgccatgtatagtcgtctccccctccaccacggcaagtcctgca gagggaaccagctctgacagttgtctgaccttctctgcgagcaaaagccccgcggggctc agtggcaccccggccactcaggggctgctgggcgcctgctccccggtcaggctggcctcg cccttcctggggtcgcagtccgccaccccagtgctgcaggctcaggggggcttgggagga gctgttctgctccctgtcagcttccaggagggacggcgggcgtcggacacctcactgact caagggctgaaggcctttcggcagcagctgaggaagaccacgcggaccaaagggtttctg ggactgaacaaaatcaaggggctggctcgccaggtgtgccaggtccctgccagccgggcc agcaggggcggcctgagccccttccacgcccctgcacagagcccaggcctgcacggcggc gcagccggcagccgggagggctggagcctgctggaggaggtgctagagcagcagaggctg ctccagttacagcaccacccggccgctgcacccggctgctcccaggccccccagccggcc cctgccccgtttgtgatcgccccctgtgatggccctggggctgccccgctccccagcacc ctcctcacgtcggggctcccgctgctgccgcccccactcctgcagaccggcgcgtccccg gtggcctcagcggcgcagctcctggacacacacctgcacattggcaccggccccaccgcc ctccccgctgtgcccccaccacgcctggccaggctggccccaggttgtgagcccctgggg ctgctgcagggggactgtgagatggaggacctgatgccctgctccctaggcacgtttgtc ctggtgcagtga

Homo sapiens (human): 150094 Help Entry 150094            CDS       T01001                                  Symbol SIK1, DEE30, MSK, SIK, SIK-1, SIK1B, SNF1LK Name (RefSeq) salt inducible kinase 1   KO K19008   serine/threonine-protein kinase SIK1 [EC:2.7.11.1] Organism hsa  Homo sapiens (human) Pathway hsa04922   Glucagon signaling pathway Disease H00606   Early infantile epileptic encephalopathy H01819   Early myoclonic encephalopathy Brite KEGG Orthology (KO) [BR:hsa00001]  09150 Organismal Systems   09152 Endocrine system    04922 Glucagon signaling pathway     150094 (SIK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hsa01001]     150094 (SIK1) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      150094 (SIK1) Protein kinases [BR:hsa01001]  Serine/threonine kinases: CAMK group   CAMKL family    150094 (SIK1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr UBA_SIK3 Kinase-like Haspin_kinase UBA_BRSK ABC1 APH Motif Other DBs NCBI-GeneID:  150094 NCBI-ProteinID:  NP_775490 OMIM:  605705 HGNC:  11142 Ensembl:  ENSG00000142178 UniProt:  P57059 LinkDB All DBs Position 21:complement(43414483..43427131) Genome browser AA seq 783 aa AA seqDB search MVIMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDK TRLDSSNLEKIYREVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGH LSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFGNFYKSGEPL STWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGR FRIPFFMSQDCESLIRRMLVVDPARRITIAQIRQHRWMRAEPCLPGPACPAFSAHSYTSN LGDYDEQALGIMQTLGVDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRNAQCARPGPAR QPRPRSSDLSGLEVPQEGLSTDPFRPALLCPQPQTLVQSVLQAEMDCELQSSLQWPLFFP VDASCSGVFRPRPVSPSSLLDTAISEEARQGPGLEEEQDTQESLPSSTGRRHTLAEVSTR LSPLTAPCIVVSPSTTASPAEGTSSDSCLTFSASKSPAGLSGTPATQGLLGACSPVRLAS PFLGSQSATPVLQAQGGLGGAVLLPVSFQEGRRASDTSLTQGLKAFRQQLRKTTRTKGFL GLNKIKGLARQVCQAPASRASRGGLSPFHAPAQSPGLHGGAAGSREGWSLLEEVLEQQRL LQLQHHPAAAPGCSQAPQPAPAPFVIAPCDGPGAAPLPSTLLTSGLPLLPPPLLQTGASP VASAAQLLDTHLHIGTGPTALPAVPPPRLARLAPGCEPLGLLQGDCEMEDLMPCSLGTFV LVQ NT seq 2352 nt NT seq  +upstreamnt  +downstreamnt atggttatcatgtcggagttcagcgcggaccccgcgggccagggtcagggccagcagaag cccctccgggtgggtttttacgacatcgagcggaccctgggcaaaggcaacttcgcggtg gtgaagctggcgcggcatcgagtcaccaaaacgcaggttgcaataaaaataattgataaa acacgattagattcaagcaatttggagaaaatctatcgtgaggttcagctgatgaagctt ctgaaccatccacacatcataaagctttaccaggttatggaaacaaaggacatgctttac atcgtcactgaatttgctaaaaatggagaaatgtttgattatttgacttccaacgggcac ctgagtgagaacgaggcgcggaagaagttctggcaaatcctgtcggccgtggagtactgt cacgaccatcacatcgtccaccgggacctcaagaccgagaacctcctgctggatggcaac atggacatcaagctggcagattttggatttgggaatttctacaagtcaggagagcctctg tccacgtggtgtgggagccccccgtatgccgccccggaagtctttgaggggaaggagtat gaaggcccccagctggacatctggagcctgggcgtggtgctgtacgtcctggtctgcggt tctctccccttcgatgggcctaacctgccgacgctgagacagcgggtgctggagggccgc ttccgcatccccttcttcatgtctcaagactgtgagagcctgatccgccgcatgctggtg gtggaccccgccaggcgcatcaccatcgcccagatccggcagcaccggtggatgcgggct gagccctgcttgccgggacccgcctgccccgccttctccgcacacagctacacctccaac ctgggcgactacgatgagcaggcgctgggtatcatgcagaccctgggcgtggaccggcag aggacggtggagtcactgcaaaacagcagctataaccactttgctgccatttattacctc ctccttgagcggctcaaggagtatcggaatgcccagtgcgcccgccccgggcctgccagg cagccgcggcctcggagctcggacctcagtggtttggaggtgcctcaggaaggtctttcc accgaccctttccgacctgccttgctgtgcccgcagccgcagaccttggtgcagtccgtc ctccaggccgagatggactgtgagctccagagctcgctgcagtggcccttgttcttcccg gtggatgccagctgcagcggagtgttccggccccggcccgtgtccccaagcagcctgctg gacacagccatcagtgaggaggccaggcaggggccgggcctagaggaggagcaggacacg caggagtccctgcccagcagcacgggccggaggcacaccctggccgaggtctccacccgc ctctccccactcaccgcgccatgtatagtcgtctccccctccaccacggcaagtcctgca gagggaaccagctctgacagttgtctgaccttctctgcgagcaaaagccccgcggggctc agtggcaccccggccactcaggggctgctgggcgcctgctccccggtcaggctggcctcg cccttcctggggtcgcagtccgccaccccagtgctgcaggctcaggggggcttgggagga gctgttctgctccctgtcagcttccaggagggacggcgggcgtcggacacctcactgact caagggctgaaggcctttcggcagcagctgaggaagaccacgcggaccaaagggtttctg ggactgaacaaaatcaaggggctggctcgccaggtgtgccaggcccccgccagccgggcc agcaggggcggcctgagccccttccacgcccctgcacagagcccaggcctgcacggcggc gcagccggcagccgggagggctggagcctgctggaggaggtgctagagcagcagaggctg ctccagttacagcaccacccggccgctgcacccggctgctcccaggccccccagccggcc cctgccccgtttgtgatcgccccctgtgatggccctggggctgccccgctccccagcacc ctcctcacgtcggggctcccgctgctgccgcccccactcctgcagaccggcgcgtccccg gtggcctcagcggcgcagctcctggacacacacctgcacattggcaccggccccaccgcc ctccccgctgtgcccccaccacgcctggccaggctggccccaggttgtgagcccctgggg ctgctgcagggggactgtgagatggaggacctgatgccctgctccctaggcacgtttgtc ctggtgcagtga

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