| Entry |
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| Symbol |
SPTLC1, ALS27, HSAN1, HSN1, LBC1, LCB1, SPT1, SPTI
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| Name |
(RefSeq) serine palmitoyltransferase long chain base subunit 1
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| KO |
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| Organism |
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| Pathway |
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| Module |
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| Network |
nt06545 Cornified envelope formation |
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| Element |
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| Disease |
| H00058 | Amyotrophic lateral sclerosis (ALS) |
| H00265 | Hereditary sensory and autonomic neuropathy |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09100 Metabolism
09103 Lipid metabolism
00600 Sphingolipid metabolism
10558 (SPTLC1)
09130 Environmental Information Processing
09132 Signal transduction
04071 Sphingolipid signaling pathway
10558 (SPTLC1)
09150 Organismal Systems
09158 Development and regeneration
04382 Cornified envelope formation
10558 (SPTLC1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01007 Amino acid related enzymes [BR:hsa01007]
10558 (SPTLC1)
Enzymes [BR:hsa01000]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.50 serine C-palmitoyltransferase
10558 (SPTLC1)
Amino acid related enzymes [BR:hsa01007]
Aminotransferase (transaminase)
Class II
10558 (SPTLC1)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
9:complement(92031147..92115413)
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| AA seq |
473 aa
MATATEQWVLVEMVQALYEAPAYHLILEGILILWIIRLLFSKTYKLQERSDLTVKEKEEL
IEEWQPEPLVPPVPKDHPALNYNIVSGPPSHKTVVNGKECINFASFNFLGLLDNPRVKAA
ALASLKKYGVGTCGPRGFYGTFDVHLDLEDRLAKFMKTEEAIIYSYGFATIASAIPAYSK
RGDIVFVDRAACFAIQKGLQASRSDIKLFKHNDMADLERLLKEQEIEDQKNPRKARVTRR
FIVVEGLYMNTGTICPLPELVKLKYKYKARIFLEESLSFGVLGEHGRGVTEHYGINIDDI
DLISANMENALASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPLLAAAAIEALNIMEENP
GIFAVLKEKCGQIHKALQGISGLKVVGESLSPAFHLQLEESTGSREQDVRLLQEIVDQCM
NRSIALTQARYLEKEEKCLPPPSIRVVVTVEQTEEELERAASTIKEVAQAVLL |
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| NT seq |
1422 nt +upstreamnt +downstreamnt
atggcgaccgccacggagcagtgggttctggtggagatggtacaggcgctttacgaggct
cctgcttaccatcttattttggaagggattctgatcctctggataatcagacttcttttc
tctaagacttacaaattacaagaacgatctgatcttacagtcaaggaaaaagaagaactg
attgaagagtggcaaccagaacctcttgttcctcctgtcccaaaagaccatcctgctctc
aactacaacatcgtttcaggccctccaagccacaaaactgtggtgaatggaaaagaatgt
ataaacttcgcctcatttaattttcttggattgttggataaccctagggttaaggcagca
gctttagcatctctaaagaagtatggcgtggggacttgtggacccagaggattttatggc
acatttgatgttcatttggatttggaagaccgcctggcaaaatttatgaagacagaagaa
gccattatatactcatatggatttgccaccatagccagtgctattcctgcttactctaaa
agaggggacattgtttttgtagatagagctgcctgctttgctattcagaaaggattacag
gcatcccgtagtgacattaagttatttaagcataatgacatggctgacctcgagcgacta
ctaaaagaacaagagatcgaagatcaaaagaatcctcgcaaggctcgtgtaactcggcgt
ttcattgtagtagaaggattgtatatgaatactggaactatttgtcctcttccagaattg
gttaagttaaaatacaaatacaaagcaagaatcttcctggaggaaagcctttcatttgga
gtcctaggagagcatggccgaggagtcactgaacactatggaatcaatattgatgatatt
gatcttatcagtgccaacatggagaatgcacttgcttctattggaggtttctgctgtggc
aggtcttttgtaattgaccatcagcgactttccggccagggatactgcttttcagcttcg
ttacctcccctgttagctgctgcagcaattgaggccctcaacatcatggaagagaatcca
ggtatttttgcagtgttgaaggaaaagtgcggacaaattcataaagctttacaaggcatt
tctggattaaaagtggtgggggagtccctttctccagcctttcacctacaactggaagag
agcactgggtctcgcgagcaagatgtcagactgcttcaggaaattgtagatcaatgcatg
aacagaagtattgcattaactcaggcgcgctacttggagaaagaagagaagtgtctccct
cctcccagcattcgggttgtggtcacggtggaacaaacagaggaagaactggagagagct
gcgtccaccatcaaggaggtagcccaggccgtcctgctctag |
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