Homo sapiens (human): 10565
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Entry
10565 CDS
T01001
Symbol
ARFGEF1, ARFGEP1, BIG1, DEDISB, P200
Name
(RefSeq) ARF guanine nucleotide exchange factor 1
KO
K18442
brefeldin A-inhibited guanine nucleotide-exchange protein
Organism
hsa
Homo sapiens (human)
Pathway
hsa04144
Endocytosis
Disease
H02685
Developmental delay with neuropsychiatric disorders
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
10565 (ARFGEF1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
10565 (ARFGEF1)
Membrane trafficking [BR:
hsa04131
]
Endosome - Golgi transport
Arf GTPases and associated proteins
Arf GTPase associated proteins
10565 (ARFGEF1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Sec7
BIG2_C
Sec7-like_HUS
DCB
Sec7-like_HDS
Motif
Other DBs
NCBI-GeneID:
10565
NCBI-ProteinID:
NP_006412
OMIM:
604141
HGNC:
15772
Ensembl:
ENSG00000066777
UniProt:
Q9Y6D6
Structure
PDB
PDBj
LinkDB
All DBs
Position
8:complement(67173511..67343781)
Genome browser
AA seq
1849 aa
AA seq
DB search
MYEGKKTKNMFLTRALEKILADKEVKKAHHSQLRKACEVALEEIKAETEKQSPPHGEAKA
GSSTLPPVKSKTNFIEADKYFLPFELACQSKCPRIVSTSLDCLQKLIAYGHLTGNAPDST
TPGKKLIDRIIETICGCFQGPQTDEGVQLQIIKALLTAVTSQHIEIHEGTVLQAVRTCYN
IYLASKNLINQTTAKATLTQMLNVIFARMENQALQEAKQMEKERHRQHHHLLQSPVSHHE
PESPQLRYLPPQTVDHISQEHEGDLDLHTNDVDKSLQDDTEPENGSDISSAENEQTEADQ
ATAAETLSKNEVLYDGENHDCEEKPQDIVQNIVEEMVNIVVGDMGEGTTINASADGNIGT
IEDGSDSENIQANGIPGTPISVAYTPSLPDDRLSVSSNDTQESGNSSGPSPGAKFSHILQ
KDAFLVFRSLCKLSMKPLSDGPPDPKSHELRSKILSLQLLLSILQNAGPIFRTNEMFINA
IKQYLCVALSKNGVSSVPEVFELSLSIFLTLLSNFKTHLKMQIEVFFKEIFLYILETSTS
SFDHKWMVIQTLTRICADAQSVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRGSQELGM
SNVQELSLRKKGLECLVSILKCMVEWSKDQYVNPNSQTTLGQEKPSEQEMSEIKHPETIN
RYGSLNSLESTSSSGIGSYSTQMSGTDNPEQFEVLKQQKEIIEQGIDLFNKKPKRGIQYL
QEQGMLGTTPEDIAQFLHQEERLDSTQVGEFLGDNDKFNKEVMYAYVDQHDFSGKDFVSA
LRMFLEGFRLPGEAQKIDRLMEKFAARYLECNQGQTLFASADTAYVLAYSIIMLTTDLHS
PQVKNKMTKEQYIKMNRGINDSKDLPEEYLSAIYNEIAGKKISMKETKELTIPTKSSKQN
VASEKQRRLLYNLEMEQMAKTAKALMEAVSHVQAPFTSATHLEHVRPMFKLAWTPFLAAF
SVGLQDCDDTEVASLCLEGIRCAIRIACIFSIQLERDAYVQALARFTLLTVSSGITEMKQ
KNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKPRYISGTVRGREGSL
TGTKDQAPDEFVGLGLVGGNVDWKQIASIQESIGETSSQSVVVAVDRIFTGSTRLDGNAI
VDFVRWLCAVSMDELLSTTHPRMFSLQKIVEISYYNMGRIRLQWSRIWEVIGDHFNKVGC
NPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKRNRSPTIRDMVVRCI
AQMVNSQAANIRSGWKNIFSVFHLAASDQDESIVELAFQTTGHIVTLVFEKHFPATIDSF
QDAVKCLSEFACNAAFPDTSMEAIRLIRHCAKYVSDRPQAFKEYTSDDMNVAPEDRVWVR
GWFPILFELSCIINRCKLDVRTRGLTVMFEIMKTYGHTYEKHWWQDLFRIVFRIFDNMKL
PEQQTEKAEWMTTTCNHALYAICDVFTQYLEVLSDVLLDDIFAQLYWCVQQDNEQLARSG
TNCLENVVILNGEKFTLEIWDKTCNCTLDIFKTTIPHALLTWRPNSGETAPPPPSPVSEK
PLDTISQKSVDIHDSIQPRSVDNRPQAPLVSASAVNEEVSKIKSTAKFPEQKLFAALLIK
CVVQLELIQTIDNIVFFPATSKKEDAENLAAAQRDAVDFDVRVDTQDQGMYRFLTSQQLF
KLLDCLLESHRFAKAFNSNNEQRTALWKAGFKGKSKPNLLKQETSSLACGLRILFRMYMD
ESRVSAWEEVQQRLLNVCSEALSYFLTLTSESHREAWTNLLLLFLTKVLKISDNRFKAHA
SFYYPLLCEIMQFDLIPELRAVLRRFFLRIGVVFQISQPPEQELGINKQ
NT seq
5550 nt
NT seq
+upstream
nt +downstream
nt
atgtatgaggggaagaagacgaagaacatgttcctgacccgggctctggagaagatattg
gccgacaaggaagtgaagaaggcgcatcactcccagctgcgcaaagcttgcgaggtggcg
ttagaggaaataaaagcggaaactgaaaaacagagtcctcctcatggagaagcaaaagct
ggatcaagcacccttccaccagtgaaatcaaagacaaattttattgaagcagacaagtac
ttcttgccttttgagttggcatgccagtccaaatgtcctcgcatagttagtacatctcta
gattgcttacagaaacttattgcttatgggcacttgactggcaatgctccagatagtaca
acaccaggcaaaaaattaattgatagaattattgaaacaatatgtggctgctttcagggc
cctcagacagatgaaggagttcagctgcagataataaaggctttacttactgcagtaaca
tcacaacacatagaaattcatgaagggactgtactgcaagctgtgagaacatgttacaat
atctacttagcaagcaaaaatctcatcaatcagacaacagccaaagctactctcactcag
atgctaaatgttatctttgcacgcatggaaaaccaagcattacaggaagcaaaacaaatg
gaaaaagaaaggcatcggcagcatcatcatctgttacagtctccagtaagccatcacgag
cctgaatcacctcaacttagatatttgccacctcagactgttgatcatatatcccaagaa
cacgaaggggaccttgacctccatacaaatgatgtagataaaagtcttcaggatgacaca
gagcctgaaaatggatctgatatttccagtgcagaaaatgaacagactgaagctgatcag
gcaactgcagctgaaacattatctaaaaatgaagtgttatatgacggagaaaaccatgat
tgtgaggaaaagccacaagacattgtacagaacattgtagaagaaatggtgaacattgtt
gttggagatatgggagaagggactactataaatgcaagtgcagatggcaacattggaact
atagaggatggtagtgacagtgaaaatattcaagcaaatggaattccaggaacaccaatt
tctgttgcatatacaccatccttacctgatgatagattgtcagtctcttccaatgatact
caggaatctggaaattcttcaggaccttcacctggtgctaagttttcccacattttacaa
aaggatgcctttctagtattcaggtcattgtgtaaactgtcaatgaaaccactgtcagat
ggaccaccagatccaaagtctcatgaactacgatccaagattctttcattgcagttactt
ctatccattctgcagaatgcaggacctattttcaggacaaatgagatgtttattaatgct
attaagcagtatctttgtgttgcactctcaaaaaatggagtctcatctgttccagaggtt
tttgagctttctctttctatatttcttactttgttgtcaaatttcaagacacatctgaag
atgcaaattgaggtgttctttaaagaaattttcttatacattttggaaacttctaccagc
tcatttgatcacaaatggatggttattcagacactgacgaggatttgtgcagatgctcag
agtgtagtggatatttatgtaaactatgactgtgacttaaatgcagccaatatatttgaa
agactagtaaatgatctatcaaaaattgctcaaggaaggggcagtcaagaacttggtatg
agtaatgttcaggaattgagcctgaggaaaaaaggtttagaatgcttagtgtcgattttg
aagtgtatggttgaatggagtaaggatcagtatgtgaatcccaactcccagacaactctt
ggtcaggaaaaaccctcagagcaagagatgagtgaaatcaaacaccctgagacaataaac
agatacggaagtttaaattccctggagtcaacatcatcatcaggaataggcagctacagt
acacagatgtctggcactgataatccagaacaatttgaggtcctaaagcaacaaaaagaa
ataatagaacaagggatagatttatttaataagaaaccaaagagaggaatacagtacctc
caagaacaagggatgcttggcaccacacctgaagatattgcccaattcttacatcaagag
gaaagattagactctactcaagtgggtgagttcctgggagataatgataaatttaacaaa
gaagtcatgtatgcatatgtggaccaacatgacttttcaggaaaagacttcgtttcagcc
cttcgtatgtttctagaaggatttcgtcttccaggggaagctcagaaaatcgatcgatta
atggaaaaatttgctgcaagatacctagaatgcaaccaaggacaaactctctttgctagt
gcggatacagcttatgttttggcttattcaattatcatgttgaccacagaccttcacagt
ccacaggtgaaaaataaaatgacaaaggaacaatacattaagatgaatagaggtatcaat
gacagtaaagaccttcctgaagagtatctatcagccatctataatgaaatagctgggaaa
aagatatcaatgaaagaaacaaaagaactaacaatccctacaaaatcaagtaaacagaat
gtagccagtgaaaaacaaagaagacttctgtataacttagaaatggagcagatggccaag
acagctaaagcactcatggaggccgtgagccatgttcaggcaccctttacaagtgcaaca
catttggagcatgtgaggcccatgtttaagttggcttggacgccttttctggctgcattc
agtgtgggtctacaagattgtgatgatactgaagtagcctctctttgcctggaaggtata
agatgtgcaatcagaattgcatgcattttcagcattcagctggagagagatgcatatgtc
caggcactagcaagatttaccttactcacagtgagttccggtattactgaaatgaaacag
aagaacattgacacaataaaaacacttatcacagtggctcatacagatggaaattattta
ggaaattcatggcatgagattctgaagtgcatcagtcagttggagctggcacagcttata
ggaactggagtgaaacctcgatacatttctggaacagtgcgaggcagagaaggatctctt
actggaacaaaagatcaggctcctgatgaatttgtgggtttagggctagttggaggaaat
gtggactggaaacagatagcaagtattcaggaatccattggagaaaccagttctcagagt
gttgttgttgctgtagatagaatattcacaggatctacaaggctagatggaaatgccatt
gtggattttgtccgttggctctgtgctgtgtctatggatgaattactttccacgacacac
ccaagaatgtttagtctacaaaaaatagtagaaatatcatattacaacatgggaagaata
agattacagtggtctcgaatttgggaagttattggagatcattttaataaggttgggtgt
aatcctaatgaagatgtagctatttttgcagtagactccttgaggcagttgtcaatgaag
ttcttagagaaaggggagcttgctaacttcagattccagaaggatttcttaagacctttt
gaacatataatgaaacggaacaggtctccaacaattcgagatatggttgtacggtgtata
gcacagatggttaattctcaagctgctaacattcgatctggatggaagaacattttctct
gtatttcatctagctgcatctgatcaagatgaaagcatagtggaacttgcattccaaaca
accgggcacattgtcacccttgtatttgaaaaacactttccagcgaccattgattctttc
caggatgcagtgaagtgtttgtctgaatttgcgtgcaatgcagctttcccagacacaagt
atggaagcaattcgacttattcgccattgtgcaaaatatgtgtctgatagacctcaggct
ttcaaggaatacacaagcgatgatatgaacgtagcacctgaagacagggtgtgggtgaga
ggatggttcccaattctctttgagttatcctgtatcatcaatagatgcaaattagatgta
agaaccaggggtttaacagtaatgtttgaaataatgaaaacatatggccacacttatgag
aaacactggtggcaggatttatttagaattgttttcagaatctttgacaatatgaaattg
ccagaacaacagacagagaaagctgaatggatgacaacaacttgcaatcatgcactttat
gcaatctgtgatgtattcactcagtatttagaagtactcagtgatgtacttttggatgac
atttttgctcagctctactggtgtgtgcagcaagacaatgagcagttagcgcgatctggt
acaaactgtttagagaatgttgttattctgaatggtgaaaaatttaccctagaaatctgg
gataaaacttgcaactgcacactggatatcttcaaaaccacaatcccacatgcgctgttg
acctggcgacccaattctggagaaactgcccccccacctccatctcctgtaagtgaaaag
ccattggatacaatatcacagaagtctgtagatattcatgattctattcaaccaaggtct
gtggataacagaccacaagcaccactggtttctgcgtctgctgttaatgaagaagtcagc
aaaattaaatctacagcaaaatttccagaacaaaaattgtttgctgccctgttgattaaa
tgtgttgtgcagctggaactcatccagactatcgacaacattgtcttcttcccagccaca
agtaagaaagaagatgcagaaaacttagctgcagcacagagagatgcggtggactttgat
gttcgcgttgatactcaagaccaaggaatgtaccgctttttaacatcacaacaacttttt
aagctactggactgcttattagagtcacatagatttgcaaaagcgtttaattccaacaac
gaacagaggactgccctgtggaaagcaggattcaaaggcaaatccaagcccaaccttctg
aagcaggagaccagcagcctggcctgtgggctgcgcattctcttccggatgtacatggat
gagagccgcgttagtgcctgggaggaggtccagcagaggcttttgaatgtctgcagtgaa
gcactaagttacttcctcactctaacatcagaaagtcatcgagaagcctggactaactta
ctgcttttgtttctaactaaagttctaaagataagtgataataggtttaaagctcatgca
tcattctactaccctctcttatgtgaaattatgcaatttgacttgattcctgaacttcgt
gctgttcttagaagattttttctgcgaatcggagtagtttttcagatatcacaaccacct
gaacaggaacttggaataaacaagcaatga
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integrated database retrieval system
