Homo sapiens (human): 1062
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Entry
1062 CDS
T01001
Symbol
CENPE, CENP-E, KIF10, MCPH13, PPP1R61
Name
(RefSeq) centromere protein E
KO
K11498
centromeric protein E
Organism
hsa
Homo sapiens (human)
Pathway
hsa04814
Motor proteins
Network
nt06515
Regulation of kinetochore-microtubule interactions
Element
N01531
CENPE interaction with NDC80 complex
N01535
Kinetochore microtubule attachment
Disease
H00269
Primary microcephaly
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09142 Cell motility
04814 Motor proteins
1062 (CENPE)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hsa01009
]
1062 (CENPE)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hsa03036
]
1062 (CENPE)
Protein phosphatases and associated proteins [BR:
hsa01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
1062 (CENPE)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Centromeric chromatin formation proteins
Kinetochore proteins
Centromere proteins
1062 (CENPE)
SAC (spindle assembly checkpoint) factors
Motor proteins
1062 (CENPE)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Kinesin
Microtub_bd
Motif
Other DBs
NCBI-GeneID:
1062
NCBI-ProteinID:
NP_001804
OMIM:
117143
HGNC:
1856
Ensembl:
ENSG00000138778
UniProt:
Q02224
Structure
PDB
LinkDB
All DBs
Position
4:complement(103105811..103198343)
Genome browser
AA seq
2701 aa
AA seq
DB search
MAEEGAVAVCVRVRPLNSREESLGETAQVYWKTDNNVIYQVDGSKSFNFDRVFHGNETTK
NVYEEIAAPIIDSAIQGYNGTIFAYGQTASGKTYTMMGSEDHLGVIPRAIHDIFQKIKKF
PDREFLLRVSYMEIYNETITDLLCGTQKMKPLIIREDVNRNVYVADLTEEVVYTSEMALK
WITKGEKSRHYGETKMNQRSSRSHTIFRMILESREKGEPSNCEGSVKVSHLNLVDLAGSE
RAAQTGAAGVRLKEGCNINRSLFILGQVIKKLSDGQVGGFINYRDSKLTRILQNSLGGNA
KTRIICTITPVSFDETLTALQFASTAKYMKNTPYVNEVSTDEALLKRYRKEIMDLKKQLE
EVSLETRAQAMEKDQLAQLLEEKDLLQKVQNEKIENLTRMLVTSSSLTLQQELKAKRKRR
VTWCLGKINKMKNSNYADQFNIPTNITTKTHKLSINLLREIDESVCSESDVFSNTLDTLS
EIEWNPATKLLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEAL
ERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDS
QKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELAT
TYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEG
KITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKL
FSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEEN
ERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRD
STLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNI
DTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQD
LEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMT
IENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQ
QQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITK
ERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSE
KTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDS
TTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQ
ESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSV
AKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNL
SEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAK
DSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKM
KESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEE
MRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKL
RGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEK
TDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQS
LTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDL
EIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKEL
QLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKE
RDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLTESLREKCSRI
KELLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSMRVKANLSLPYLQTKHIEKLFTANQ
RCSMEFHRIMKKLKYVLSYVTKIKEEQHESINKFEMDFIDEVEKQKELLIKIQHLQQDCD
VPSRELRDLKLNQNMDLHIEEILKDFSESEFPSIKTEFQQVLSNRKEMTQFLEEWLNTRF
DIEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATISKEWEQDLKSLKEKNE
KLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAKESAMHK
ESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVALGAKPYKEEIEDL
KMKLVKIDLEKMKNAKEFEKEISATKATVEYQKEVIRLLRENLRRSQQAQDTSVISEHTD
PQPSNKPLTCGGGSGIVQNTKALILKSEHIRLEKEISKLKQQNEQLIKQKNELLSNNQHL
SNEVKTWKERTLKREAHKQVTCENSPKSPKVTGTASKKKQITPSQCKERNLQDPVPKESP
KSCFFDSRSKSLPSPHPVRYFDNSSLGLCPEVQNAGAESVDSQPGPWHASSGKDVPECKT
Q
NT seq
8106 nt
NT seq
+upstream
nt +downstream
nt
atggcggaggaaggagccgtggccgtctgcgtgcgagtgcggccgctgaacagcagagaa
gaatcacttggagaaactgcccaagtttactggaaaactgacaataatgtcatttatcaa
gttgatggaagtaaatccttcaattttgatcgtgtctttcatggtaatgaaactaccaaa
aatgtgtatgaagaaatagcagcaccaatcatcgattctgccatacaaggctacaatggt
actatatttgcctatggacagactgcttcaggaaaaacatataccatgatgggttcagaa
gatcatttgggagttatacccagggcaattcatgacattttccaaaaaattaagaagttt
cctgatagggaatttctcttacgtgtatcttacatggaaatatacaatgaaaccattaca
gatttactctgtggcactcaaaaaatgaaacctttaattattcgagaagatgtcaatagg
aatgtgtatgttgctgatctcacagaagaagttgtatatacatcagaaatggctttgaaa
tggattacaaagggagaaaagagcaggcattatggagaaacaaaaatgaatcaaagaagc
agtcgttctcataccatctttaggatgattttggaaagcagagagaagggtgaaccttct
aattgtgaaggatctgttaaggtatcccatttgaatttggttgatcttgcaggcagtgaa
agagctgctcaaacaggcgctgcaggtgtgcggctcaaggaaggctgtaatataaatcga
agcttatttattttgggacaagtgatcaagaaacttagtgatggacaagttggtggtttc
ataaattatcgagatagcaagttaacacgaattctccagaattccttgggaggaaatgca
aagacacgtattatctgcacaattactccagtatcttttgatgaaacacttactgctctc
cagtttgccagtactgctaaatatatgaagaatactccttatgttaatgaggtatcaact
gatgaagctctcctgaaaaggtatagaaaagaaataatggatcttaaaaaacaattagag
gaggtttctttagagacgcgggctcaggcaatggaaaaagaccaattggcccaacttttg
gaagaaaaagatttgcttcagaaagtacagaatgagaaaattgaaaacttaacacggatg
ctggtgacctcttcttccctcacgttgcaacaggaattaaaggctaaaagaaaacgaaga
gttacttggtgccttggcaaaattaacaaaatgaagaactcaaactatgcagatcaattt
aatataccaacaaatataacaacaaaaacacataagctttctataaatttattacgagaa
attgatgaatctgtctgttcagagtctgatgttttcagtaacactcttgatacattaagt
gagatagaatggaatccagcaacaaagctactaaatcaggagaatatagaaagtgagttg
aactcacttcgtgctgactatgataatctggtattagactatgaacaactacgaacagaa
aaagaagaaatggaattgaaattaaaagaaaagaatgatttggatgaatttgaggctcta
gaaagaaaaactaaaaaagatcaagagatgcaactaattcatgaaatttcgaacttaaag
aatttagttaagcatgcagaagtatataatcaagatcttgagaatgaactcagttcaaaa
gtagagctgcttagagaaaaggaagaccagattaagaagctacaggaatacatagactct
caaaagctagaaaatataaaaatggacttgtcatactcattggaaagcattgaagaccca
aaacaaatgaagcagactctgtttgatgctgaaactgtagcccttgatgccaagagagaa
tcagcctttcttagaagtgaaaatctggagctgaaggagaaaatgaaagaacttgcaact
acatacaagcaaatggaaaatgatattcagttatatcaaagccagttggaggcaaaaaag
aaaatgcaagttgatctggagaaagaattacaatctgcttttaatgagataacaaaactc
acctcccttatagatggcaaagttccaaaagatttgctctgtaatttggaattggaagga
aagattactgatcttcagaaagaactaaataaagaagttgaagaaaatgaagctttgcgg
gaagaagtcattttgctttcagaattgaaatctttaccttctgaagtagaaaggctgagg
aaagagatacaagacaaatctgaagagctccatataataacatcagaaaaagataaattg
ttttctgaagtagttcataaggagagtagagttcaaggtttacttgaagaaattgggaaa
acaaaagatgacctagcaactacacagtcgaattataaaagcactgatcaagaattccaa
aatttcaaaacccttcatatggactttgagcaaaagtataagatggtccttgaggagaat
gagagaatgaatcaggaaatagttaatctctctaaagaagcccaaaaatttgattcgagt
ttgggtgctttgaagaccgagctttcttacaagacccaagaacttcaggagaaaacacgt
gaggttcaagaaagactaaatgagatggaacagctgaaggaacaattagaaaatagagat
tctacgctgcaaactgtagaaagggagaaaacactgattactgagaaactgcagcaaact
ttagaagaagtaaaaactttaactcaagaaaaagatgatctaaaacaactccaagaaagc
ttgcaaattgagagggaccaactcaaaagtgatattcacgatactgttaacatgaatata
gatactcaagaacaattacgaaatgctcttgagtctctgaaacaacatcaagaaacaatt
aatacactaaaatcgaaaatttctgaggaagtttccaggaatttgcatatggaggaaaat
acaggagaaactaaagatgaatttcagcaaaagatggttggcatagataaaaaacaggat
ttggaagctaaaaatacccaaacactaactgcagatgttaaggataatgagataattgag
caacaaaggaagatattttctttaatacaggagaaaaatgaactccaacaaatgttagag
agtgttatagcagaaaaggaacaattgaagactgacctaaaggaaaatattgaaatgacc
attgaaaaccaggaagaattaagacttcttggggatgaacttaaaaagcaacaagagata
gttgcacaagaaaagaaccatgccataaagaaagaaggagagctttctaggacctgtgac
agactggcagaagttgaagaaaaactaaaggaaaagagccagcaactccaagaaaaacag
caacaacttcttaatgtacaagaagagatgagtgagatgcagaaaaagattaatgaaata
gagaatttaaagaatgaattaaagaacaaagaattgacattggaacatatggaaacagag
aggcttgagttggctcagaaacttaatgaaaattatgaggaagtgaaatctataaccaaa
gaaagaaaagttctaaaggaattacagaagtcatttgaaacagagagagaccaccttaga
ggatatataagagaaattgaagctacaggcctacaaaccaaagaagaactaaaaattgct
catattcacctaaaagaacaccaagaaactattgatgaactaagaagaagcgtatctgag
aagacagctcaaataataaatactcaggacttagaaaaatcccataccaaattacaagaa
gagatcccagtgcttcatgaggaacaagagttactgcctaatgtgaaagaagtcagtgag
actcaggaaacaatgaatgaactggagttattaacagaacagtccacaaccaaggactca
acaacactggcaagaatagaaatggaaaggctcaggttgaatgaaaaatttcaagaaagt
caggaagagataaaatctctaaccaaggaaagagacaaccttaaaacgataaaagaagcc
cttgaagttaaacatgaccagctgaaagaacatattagagaaactttggctaaaatccag
gagtctcaaagcaaacaagaacagtccttaaatatgaaagaaaaagacaatgaaactacc
aaaatcgtgagtgagatggagcaattcaaacccaaagattcagcactactaaggatagaa
atagaaatgctcggattgtccaaaagacttcaagaaagtcatgatgaaatgaaatctgta
gctaaggagaaagatgacctacagaggctgcaagaagttcttcaatctgaaagtgaccag
ctcaaagaaaacataaaagaaattgtagctaaacacctggaaactgaagaggaacttaaa
gttgctcattgttgcctgaaagaacaagaggaaactattaatgagttaagagtgaatctt
tcagagaaggaaactgaaatatcaaccattcaaaagcagttagaagcaatcaatgataaa
ttacagaacaagatccaagagatttatgagaaagaggaacaatttaatataaaacaaatt
agtgaggttcaggaaaaagtgaatgaactgaaacaattcaaggagcatcgcaaagccaag
gattcagcactacaaagtatagaaagtaagatgctcgagttgaccaacagacttcaagaa
agtcaagaagaaatacaaattatgattaaggaaaaagaggaaatgaaaagagtacaggag
gcccttcagatagagagagaccaactgaaagaaaacactaaagaaattgtagctaaaatg
aaagaatctcaagaaaaagaatatcagtttcttaagatgacagctgtcaatgagactcag
gagaaaatgtgtgaaatagaacacttgaaggagcaatttgagacccagaagttaaacctg
gaaaacatagaaacggagaatataaggttgactcagatactacatgaaaaccttgaagaa
atgagatctgtaacaaaagaaagagatgaccttaggagtgtggaggagactctcaaagta
gagagagaccagctcaaggaaaaccttagagaaactataactagagacctagaaaaacaa
gaggagctaaaaattgttcacatgcatctgaaggagcaccaagaaactattgataaacta
agagggattgtttcagagaaaacaaatgaaatatcaaatatgcaaaaggacttagaacac
tcaaatgatgccttaaaagcacaggatctgaaaatacaagaggaactaagaattgctcac
atgcatctgaaagagcagcaggaaactattgacaaactcagaggaattgtttctgagaag
acagataaactatcaaatatgcaaaaagatttagaaaattcaaatgctaaattacaagaa
aagattcaagaacttaaggcaaatgaacatcaacttattacgttaaaaaaagatgtcaat
gagacacagaaaaaagtgtctgaaatggagcaactaaagaaacaaataaaagaccaaagc
ttaactctgagtaaattagaaatagagaatttaaatttggctcagaaacttcatgaaaac
cttgaagaaatgaaatctgtaatgaaagaaagagataatctaagaagagtagaggagaca
ctcaaactggagagagaccaactcaaggaaagcctgcaagaaaccaaagctagagatctg
gaaatacaacaggaactaaaaactgctcgtatgctatcaaaagaacacaaagaaactgtt
gataaacttagagaaaaaatttcagaaaagacaattcaaatttcagacattcaaaaggat
ttagataaatcaaaagatgaattacagaaaaagatccaagaacttcagaaaaaagaactt
caactgcttagagtgaaagaagatgtcaatatgagtcataaaaaaattaatgaaatggaa
cagttgaagaagcaatttgaggcccaaaacttatctatgcaaagtgtgagaatggataac
ttccagttgactaagaaacttcatgaaagccttgaagaaataagaattgtagctaaagaa
agagatgagctaaggaggataaaagaatctctcaaaatggaaagggaccaattcatagca
accttaagggaaatgatagctagagaccgacagaaccaccaagtaaaacctgaaaaaagg
ttactaagtgatggacaacagcaccttacggaaagcctgagagaaaagtgctctagaata
aaagagcttttgaagagatactcagagatggatgatcattatgagtgcttgaatagattg
tctcttgacttggagaaggaaattgaattccaaaaagagctttcaatgagagttaaagca
aacctctcacttccctatttacaaaccaaacacattgaaaaactttttactgcaaaccag
agatgctccatggaattccacagaatcatgaagaaactgaagtatgtgttaagctatgtt
acaaaaataaaagaagaacaacatgaatccatcaataaatttgaaatggattttattgat
gaagtggaaaagcaaaaggaattgctaattaaaatacagcaccttcaacaagattgtgat
gtaccatccagagaattaagggatctcaaattgaaccagaatatggatctacatattgag
gaaattctcaaagatttctcagaaagtgagttccctagcataaagactgaatttcaacaa
gtactaagtaataggaaagaaatgacacagtttttggaagagtggttaaatactcgtttt
gatatagaaaagcttaaaaatggcatccagaaagaaaatgataggatttgtcaagtgaat
aacttctttaataacagaataattgccataatgaatgaatcaacagagtttgaggaaaga
agtgctaccatatccaaagagtgggaacaggacctgaaatcactgaaagagaaaaatgaa
aaactatttaaaaactaccaaacattgaagacttccttggcatctggtgcccaggttaat
cctaccacacaagacaataagaatcctcatgttacatcaagagctacacagttaaccaca
gagaaaattcgagagctggaaaattcactgcatgaagctaaagaaagtgctatgcataag
gaaagcaagattataaagatgcagaaagaacttgaggtgactaatgacataatagcaaaa
cttcaagccaaagttcatgaatcaaataaatgccttgaaaaaacaaaagagacaattcaa
gtacttcaggacaaagttgctttaggagctaagccatataaagaagaaattgaagatctc
aaaatgaagcttgtgaaaatagacctagagaaaatgaaaaatgccaaagaatttgaaaag
gaaatcagtgctacaaaagccactgtagaatatcaaaaggaagttataaggctattgaga
gaaaatctcagaagaagtcaacaggcccaagatacctcagtgatatcagaacatactgat
cctcagccttcaaataaacccttaacttgtggaggtggcagcggcattgtacaaaacaca
aaagctcttattttgaaaagtgaacatataaggctagaaaaagaaatttctaagttaaag
cagcaaaatgaacagctaataaaacaaaagaatgaattgttaagcaataatcagcatctt
tccaatgaggtcaaaacttggaaggaaagaacccttaaaagagaggctcacaaacaagta
acttgtgagaattctccaaagtctcctaaagtgactggaacagcttctaaaaagaaacaa
attacaccctctcaatgcaaggaacggaatttacaagatcctgtgccaaaggaatcacca
aaatcttgtttttttgatagccgatcaaagtctttaccatcacctcatccagttcgctat
tttgataactcaagtttaggcctttgtccagaggtgcaaaatgcaggagcagagagtgtg
gattctcagccaggtccttggcacgcctcctcaggcaaggatgtgcctgagtgcaaaact
cagtag
DBGET
integrated database retrieval system
