Homo sapiens (human): 1062
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Entry
1062 CDS
T01001
Symbol
CENPE, CENP-E, KIF10, MCPH13, PPP1R61
Name
(RefSeq) centromere-associated protein E isoform 1 precursor
KO
K11498
centromeric protein E
Organism
hsa
Homo sapiens (human)
Pathway
hsa04814
Motor proteins
Network
nt06515
Regulation of kinetochore-microtubule interactions
Element
N01531
CENPE interaction with NDC80 complex
N01535
Kinetochore microtubule attachment
Disease
H00269
Primary microcephaly
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09142 Cell motility
04814 Motor proteins
1062 (CENPE)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hsa01009
]
1062 (CENPE)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hsa03036
]
1062 (CENPE)
Protein phosphatases and associated proteins [BR:
hsa01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
1062 (CENPE)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Centromeric chromatin formation proteins
Kinetochore proteins
Centromere proteins
1062 (CENPE)
SAC (spindle assembly checkpoint) factors
Motor proteins
1062 (CENPE)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Kinesin
Microtub_bd
Motif
Other DBs
NCBI-GeneID:
1062
NCBI-ProteinID:
NP_001804
OMIM:
117143
HGNC:
1856
Ensembl:
ENSP00000265148.3
UniProt:
Q02224
Structure
PDB
PDBj
LinkDB
All DBs
Position
4:complement(103105811..103198343)
Genome browser
AA seq
2701 aa
AA seq
DB search
MAEEGAVAVCVRVRPLNSREESLGETAQVYWKTDNNVIYQVDGSKSFNFDRVFHGNETTK
NVYEEIAAPIIDSAIQGYNGTIFAYGQTASGKTYTMMGSEDHLGVIPRAIHDIFQKIKKF
PDREFLLRVSYMEIYNETITDLLCGTQKMKPLIIREDVNRNVYVADLTEEVVYTSEMALK
WITKGEKSRHYGETKMNQRSSRSHTIFRMILESREKGEPSNCEGSVKVSHLNLVDLAGSE
RAAQTGAAGVRLKEGCNINRSLFILGQVIKKLSDGQVGGFINYRDSKLTRILQNSLGGNA
KTRIICTITPVSFDETLTALQFASTAKYMKNTPYVNEVSTDEALLKRYRKEIMDLKKQLE
EVSLETRAQAMEKDQLAQLLEEKDLLQKVQNEKIENLTRMLVTSSSLTLQQELKAKRKRR
VTWCLGKINKMKNSNYADQFNIPTNITTKTHKLSINLLREIDESVCSESDVFSNTLDTLS
EIEWNPATKLLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEAL
ERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDS
QKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELAT
TYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEG
KITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKL
FSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEEN
ERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRD
STLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNI
DTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQD
LEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMT
IENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQ
QQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITK
ERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSE
KTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDS
TTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQ
ESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSV
AKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNL
SEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAK
DSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKM
KESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEE
MRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKL
RGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEK
TDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQS
LTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDL
EIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKEL
QLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKE
RDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLTESLREKCSRI
KELLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSMRVKANLSLPYLQTKHIEKLFTANQ
RCSMEFHRIMKKLKYVLSYVTKIKEEQHESINKFEMDFIDEVEKQKELLIKIQHLQQDCD
VPSRELRDLKLNQNMDLHIEEILKDFSESEFPSIKTEFQQVLSNRKEMTQFLEEWLNTRF
DIEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATISKEWEQDLKSLKEKNE
KLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAKESAMHK
ESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVALGAKPYKEEIEDL
KMKLVKIDLEKMKNAKEFEKEISATKATVEYQKEVIRLLRENLRRSQQAQDTSVISEHTD
PQPSNKPLTCGGGSGIVQNTKALILKSEHIRLEKEISKLKQQNEQLIKQKNELLSNNQHL
SNEVKTWKERTLKREAHKQVTCENSPKSPKVTGTASKKKQITPSQCKERNLQDPVPKESP
KSCFFDSRSKSLPSPHPVRYFDNSSLGLCPEVQNAGAESVDSQPGPWHASSGKDVPECKT
Q
NT seq
8106 nt
NT seq
+upstream
nt +downstream
nt
atggcggaggaaggagccgtggccgtctgcgtgcgagtgcggccgctgaacagcagagaa
gaatcacttggagaaactgcccaagtttactggaaaactgacaataatgtcatttatcaa
gttgatggaagtaaatccttcaattttgatcgtgtctttcatggtaatgaaactaccaaa
aatgtgtatgaagaaatagcagcaccaatcatcgattctgccatacaaggctacaatggt
actatatttgcctatggacagactgcttcaggaaaaacatataccatgatgggttcagaa
gatcatttgggagttatacccagggcaattcatgacattttccaaaaaattaagaagttt
cctgatagggaatttctcttacgtgtatcttacatggaaatatacaatgaaaccattaca
gatttactctgtggcactcaaaaaatgaaacctttaattattcgagaagatgtcaatagg
aatgtgtatgttgctgatctcacagaagaagttgtatatacatcagaaatggctttgaaa
tggattacaaagggagaaaagagcaggcattatggagaaacaaaaatgaatcaaagaagc
agtcgttctcataccatctttaggatgattttggaaagcagagagaagggtgaaccttct
aattgtgaaggatctgttaaggtatcccatttgaatttggttgatcttgcaggcagtgaa
agagctgctcaaacaggcgctgcaggtgtgcggctcaaggaaggctgtaatataaatcga
agcttatttattttgggacaagtgatcaagaaacttagtgatggacaagttggtggtttc
ataaattatcgagatagcaagttaacacgaattctccagaattccttgggaggaaatgca
aagacacgtattatctgcacaattactccagtatcttttgatgaaacacttactgctctc
cagtttgccagtactgctaaatatatgaagaatactccttatgttaatgaggtatcaact
gatgaagctctcctgaaaaggtatagaaaagaaataatggatcttaaaaaacaattagag
gaggtttctttagagacgcgggctcaggcaatggaaaaagaccaattggcccaacttttg
gaagaaaaagatttgcttcagaaagtacagaatgagaaaattgaaaacttaacacggatg
ctggtgacctcttcttccctcacgttgcaacaggaattaaaggctaaaagaaaacgaaga
gttacttggtgccttggcaaaattaacaaaatgaagaactcaaactatgcagatcaattt
aatataccaacaaatataacaacaaaaacacataagctttctataaatttattacgagaa
attgatgaatctgtctgttcagagtctgatgttttcagtaacactcttgatacattaagt
gagatagaatggaatccagcaacaaagctactaaatcaggagaatatagaaagtgagttg
aactcacttcgtgctgactatgataatctggtattagactatgaacaactacgaacagaa
aaagaagaaatggaattgaaattaaaagaaaagaatgatttggatgaatttgaggctcta
gaaagaaaaactaaaaaagatcaagagatgcaactaattcatgaaatttcgaacttaaag
aatttagttaagcatgcagaagtatataatcaagatcttgagaatgaactcagttcaaaa
gtagagctgcttagagaaaaggaagaccagattaagaagctacaggaatacatagactct
caaaagctagaaaatataaaaatggacttgtcatactcattggaaagcattgaagaccca
aaacaaatgaagcagactctgtttgatgctgaaactgtagcccttgatgccaagagagaa
tcagcctttcttagaagtgaaaatctggagctgaaggagaaaatgaaagaacttgcaact
acatacaagcaaatggaaaatgatattcagttatatcaaagccagttggaggcaaaaaag
aaaatgcaagttgatctggagaaagaattacaatctgcttttaatgagataacaaaactc
acctcccttatagatggcaaagttccaaaagatttgctctgtaatttggaattggaagga
aagattactgatcttcagaaagaactaaataaagaagttgaagaaaatgaagctttgcgg
gaagaagtcattttgctttcagaattgaaatctttaccttctgaagtagaaaggctgagg
aaagagatacaagacaaatctgaagagctccatataataacatcagaaaaagataaattg
ttttctgaagtagttcataaggagagtagagttcaaggtttacttgaagaaattgggaaa
acaaaagatgacctagcaactacacagtcgaattataaaagcactgatcaagaattccaa
aatttcaaaacccttcatatggactttgagcaaaagtataagatggtccttgaggagaat
gagagaatgaatcaggaaatagttaatctctctaaagaagcccaaaaatttgattcgagt
ttgggtgctttgaagaccgagctttcttacaagacccaagaacttcaggagaaaacacgt
gaggttcaagaaagactaaatgagatggaacagctgaaggaacaattagaaaatagagat
tctacgctgcaaactgtagaaagggagaaaacactgattactgagaaactgcagcaaact
ttagaagaagtaaaaactttaactcaagaaaaagatgatctaaaacaactccaagaaagc
ttgcaaattgagagggaccaactcaaaagtgatattcacgatactgttaacatgaatata
gatactcaagaacaattacgaaatgctcttgagtctctgaaacaacatcaagaaacaatt
aatacactaaaatcgaaaatttctgaggaagtttccaggaatttgcatatggaggaaaat
acaggagaaactaaagatgaatttcagcaaaagatggttggcatagataaaaaacaggat
ttggaagctaaaaatacccaaacactaactgcagatgttaaggataatgagataattgag
caacaaaggaagatattttctttaatacaggagaaaaatgaactccaacaaatgttagag
agtgttatagcagaaaaggaacaattgaagactgacctaaaggaaaatattgaaatgacc
attgaaaaccaggaagaattaagacttcttggggatgaacttaaaaagcaacaagagata
gttgcacaagaaaagaaccatgccataaagaaagaaggagagctttctaggacctgtgac
agactggcagaagttgaagaaaaactaaaggaaaagagccagcaactccaagaaaaacag
caacaacttcttaatgtacaagaagagatgagtgagatgcagaaaaagattaatgaaata
gagaatttaaagaatgaattaaagaacaaagaattgacattggaacatatggaaacagag
aggcttgagttggctcagaaacttaatgaaaattatgaggaagtgaaatctataaccaaa
gaaagaaaagttctaaaggaattacagaagtcatttgaaacagagagagaccaccttaga
ggatatataagagaaattgaagctacaggcctacaaaccaaagaagaactaaaaattgct
catattcacctaaaagaacaccaagaaactattgatgaactaagaagaagcgtatctgag
aagacagctcaaataataaatactcaggacttagaaaaatcccataccaaattacaagaa
gagatcccagtgcttcatgaggaacaagagttactgcctaatgtgaaagaagtcagtgag
actcaggaaacaatgaatgaactggagttattaacagaacagtccacaaccaaggactca
acaacactggcaagaatagaaatggaaaggctcaggttgaatgaaaaatttcaagaaagt
caggaagagataaaatctctaaccaaggaaagagacaaccttaaaacgataaaagaagcc
cttgaagttaaacatgaccagctgaaagaacatattagagaaactttggctaaaatccag
gagtctcaaagcaaacaagaacagtccttaaatatgaaagaaaaagacaatgaaactacc
aaaatcgtgagtgagatggagcaattcaaacccaaagattcagcactactaaggatagaa
atagaaatgctcggattgtccaaaagacttcaagaaagtcatgatgaaatgaaatctgta
gctaaggagaaagatgacctacagaggctgcaagaagttcttcaatctgaaagtgaccag
ctcaaagaaaacataaaagaaattgtagctaaacacctggaaactgaagaggaacttaaa
gttgctcattgttgcctgaaagaacaagaggaaactattaatgagttaagagtgaatctt
tcagagaaggaaactgaaatatcaaccattcaaaagcagttagaagcaatcaatgataaa
ttacagaacaagatccaagagatttatgagaaagaggaacaatttaatataaaacaaatt
agtgaggttcaggaaaaagtgaatgaactgaaacaattcaaggagcatcgcaaagccaag
gattcagcactacaaagtatagaaagtaagatgctcgagttgaccaacagacttcaagaa
agtcaagaagaaatacaaattatgattaaggaaaaagaggaaatgaaaagagtacaggag
gcccttcagatagagagagaccaactgaaagaaaacactaaagaaattgtagctaaaatg
aaagaatctcaagaaaaagaatatcagtttcttaagatgacagctgtcaatgagactcag
gagaaaatgtgtgaaatagaacacttgaaggagcaatttgagacccagaagttaaacctg
gaaaacatagaaacggagaatataaggttgactcagatactacatgaaaaccttgaagaa
atgagatctgtaacaaaagaaagagatgaccttaggagtgtggaggagactctcaaagta
gagagagaccagctcaaggaaaaccttagagaaactataactagagacctagaaaaacaa
gaggagctaaaaattgttcacatgcatctgaaggagcaccaagaaactattgataaacta
agagggattgtttcagagaaaacaaatgaaatatcaaatatgcaaaaggacttagaacac
tcaaatgatgccttaaaagcacaggatctgaaaatacaagaggaactaagaattgctcac
atgcatctgaaagagcagcaggaaactattgacaaactcagaggaattgtttctgagaag
acagataaactatcaaatatgcaaaaagatttagaaaattcaaatgctaaattacaagaa
aagattcaagaacttaaggcaaatgaacatcaacttattacgttaaaaaaagatgtcaat
gagacacagaaaaaagtgtctgaaatggagcaactaaagaaacaaataaaagaccaaagc
ttaactctgagtaaattagaaatagagaatttaaatttggctcagaaacttcatgaaaac
cttgaagaaatgaaatctgtaatgaaagaaagagataatctaagaagagtagaggagaca
ctcaaactggagagagaccaactcaaggaaagcctgcaagaaaccaaagctagagatctg
gaaatacaacaggaactaaaaactgctcgtatgctatcaaaagaacacaaagaaactgtt
gataaacttagagaaaaaatttcagaaaagacaattcaaatttcagacattcaaaaggat
ttagataaatcaaaagatgaattacagaaaaagatccaagaacttcagaaaaaagaactt
caactgcttagagtgaaagaagatgtcaatatgagtcataaaaaaattaatgaaatggaa
cagttgaagaagcaatttgaggcccaaaacttatctatgcaaagtgtgagaatggataac
ttccagttgactaagaaacttcatgaaagccttgaagaaataagaattgtagctaaagaa
agagatgagctaaggaggataaaagaatctctcaaaatggaaagggaccaattcatagca
accttaagggaaatgatagctagagaccgacagaaccaccaagtaaaacctgaaaaaagg
ttactaagtgatggacaacagcaccttacggaaagcctgagagaaaagtgctctagaata
aaagagcttttgaagagatactcagagatggatgatcattatgagtgcttgaatagattg
tctcttgacttggagaaggaaattgaattccaaaaagagctttcaatgagagttaaagca
aacctctcacttccctatttacaaaccaaacacattgaaaaactttttactgcaaaccag
agatgctccatggaattccacagaatcatgaagaaactgaagtatgtgttaagctatgtt
acaaaaataaaagaagaacaacatgaatccatcaataaatttgaaatggattttattgat
gaagtggaaaagcaaaaggaattgctaattaaaatacagcaccttcaacaagattgtgat
gtaccatccagagaattaagggatctcaaattgaaccagaatatggatctacatattgag
gaaattctcaaagatttctcagaaagtgagttccctagcataaagactgaatttcaacaa
gtactaagtaataggaaagaaatgacacagtttttggaagagtggttaaatactcgtttt
gatatagaaaagcttaaaaatggcatccagaaagaaaatgataggatttgtcaagtgaat
aacttctttaataacagaataattgccataatgaatgaatcaacagagtttgaggaaaga
agtgctaccatatccaaagagtgggaacaggacctgaaatcactgaaagagaaaaatgaa
aaactatttaaaaactaccaaacattgaagacttccttggcatctggtgcccaggttaat
cctaccacacaagacaataagaatcctcatgttacatcaagagctacacagttaaccaca
gagaaaattcgagagctggaaaattcactgcatgaagctaaagaaagtgctatgcataag
gaaagcaagattataaagatgcagaaagaacttgaggtgactaatgacataatagcaaaa
cttcaagccaaagttcatgaatcaaataaatgccttgaaaaaacaaaagagacaattcaa
gtacttcaggacaaagttgctttaggagctaagccatataaagaagaaattgaagatctc
aaaatgaagcttgtgaaaatagacctagagaaaatgaaaaatgccaaagaatttgaaaag
gaaatcagtgctacaaaagccactgtagaatatcaaaaggaagttataaggctattgaga
gaaaatctcagaagaagtcaacaggcccaagatacctcagtgatatcagaacatactgat
cctcagccttcaaataaacccttaacttgtggaggtggcagcggcattgtacaaaacaca
aaagctcttattttgaaaagtgaacatataaggctagaaaaagaaatttctaagttaaag
cagcaaaatgaacagctaataaaacaaaagaatgaattgttaagcaataatcagcatctt
tccaatgaggtcaaaacttggaaggaaagaacccttaaaagagaggctcacaaacaagta
acttgtgagaattctccaaagtctcctaaagtgactggaacagcttctaaaaagaaacaa
attacaccctctcaatgcaaggaacggaatttacaagatcctgtgccaaaggaatcacca
aaatcttgtttttttgatagccgatcaaagtctttaccatcacctcatccagttcgctat
tttgataactcaagtttaggcctttgtccagaggtgcaaaatgcaggagcagagagtgtg
gattctcagccaggtccttggcacgcctcctcaggcaaggatgtgcctgagtgcaaaact
cagtag
DBGET
integrated database retrieval system
