KEGG   NETWORK: N01531
Entry
N01531                      Network                                
Name
CENPE interaction with NDC80 complex
Definition
(AURKA,AURKB) -| PP1 -- CENPE+(SKAP+Astrin) == NDC80C
  Expanded
(6790,9212) -| (5499+5500+5501) -- 1062+(90417+10615) == (10403+83540+147841+57405)
Class
nt06515 Regulation of kinetochore-microtubule interactions
Type
Reference
Gene
6790  AURKA; aurora kinase A
9212  AURKB; aurora kinase B
5499  PPP1CA; protein phosphatase 1 catalytic subunit alpha
5500  PPP1CB; protein phosphatase 1 catalytic subunit beta
5501  PPP1CC; protein phosphatase 1 catalytic subunit gamma
1062  CENPE; centromere protein E
90417  KNSTRN; kinetochore localized astrin (SPAG5) binding protein
10615  SPAG5; sperm associated antigen 5
10403  NDC80; NDC80 kinetochore complex component
83540  NUF2; NUF2 component of NDC80 kinetochore complex
147841  SPC24; SPC24 component of NDC80 kinetochore complex
57405  SPC25; SPC25 component of NDC80 kinetochore complex
Reference
PMID:22110139
  Authors
Huang Y, Wang W, Yao P, Wang X, Liu X, Zhuang X, Yan F, Zhou J, Du J, Ward T, Zou H, Zhang J, Fang G, Ding X, Dou Z, Yao X
  Title
CENP-E kinesin interacts with SKAP protein to orchestrate accurate chromosome segregation in mitosis.
  Journal
J Biol Chem 287:1500-9 (2012)
DOI:10.1074/jbc.M111.277194
Reference
PMID:28841134
  Authors
Kern DM, Monda JK, Su KC, Wilson-Kubalek EM, Cheeseman IM
  Title
Astrin-SKAP complex reconstitution reveals its kinetochore interaction with microtubule-bound Ndc80.
  Journal
Elife 6:e26866 (2017)
DOI:10.7554/eLife.26866
Reference
PMID:17535814
  Authors
Liu D, Ding X, Du J, Cai X, Huang Y, Ward T, Shaw A, Yang Y, Hu R, Jin C, Yao X
  Title
Human NUF2 interacts with centromere-associated protein E and is essential for a stable spindle microtubule-kinetochore attachment.
  Journal
J Biol Chem 282:21415-24 (2007)
DOI:10.1074/jbc.M609026200
Reference
PMID:30784092
  Authors
Yu KW, Zhong N, Xiao Y, She ZY
  Title
Mechanisms of kinesin-7 CENP-E in kinetochore-microtubule capture and chromosome alignment during cell division.
  Journal
Biol Cell 111:143-160 (2019)
DOI:10.1111/boc.201800082
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