Homo sapiens (human): 10641
Help
Entry
10641 CDS
T01001
Symbol
NPRL2, FFEVF2, NPR2, NPR2L, TUSC4
Name
(RefSeq) NPR2 like, GATOR1 complex subunit
KO
K20405
nitrogen permease regulator 2
Organism
hsa
Homo sapiens (human)
Pathway
hsa04150
mTOR signaling pathway
Network
nt06522
mTOR signaling
Element
N01578
GATOR1-mTORC1 signaling pathway
Disease
H02214
Familial focal epilepsy with variable foci
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04150 mTOR signaling pathway
10641 (NPRL2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
10641 (NPRL2)
Membrane trafficking [BR:
hsa04131
]
Autophagy
Other autophagy associated proteins
SEACIT/GATOR1 complex
10641 (NPRL2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NPR2
SAM_TNK
FAS_I_H
Motif
Other DBs
NCBI-GeneID:
10641
NCBI-ProteinID:
NP_006536
OMIM:
607072
HGNC:
24969
Ensembl:
ENSG00000114388
UniProt:
Q8WTW4
Structure
PDB
PDBj
LinkDB
All DBs
Position
3:complement(50347330..50350775)
Genome browser
AA seq
380 aa
AA seq
DB search
MGSGCRIECIFFSEFHPTLGPKITYQVPEDFISRELFDTVQVYIITKPELQNKLITVTAM
EKKLIGCPVCIEHKKYSRNALLFNLGFVCDAQAKTCALEPIVKKLAGYLTTLELESSFVS
MEESKQKLVPIMTILLEELNASGRCTLPIDESNTIHLKVIEQRPDPPVAQEYDVPVFTKD
KEDFFNSQWDLTTQQILPYIDGFRHIQKISAEADVELNLVRIAIQNLLYYGVVTLVSILQ
YSNVYCPTPKVQDLVDDKSLQEACLSYVTKQGHKRASLRDVFQLYCSLSPGTTVRDLIGR
HPQQLQHVDERKLIQFGLMKNLIRRLQKYPVRVTREEQSHPARLYTGCHSYDEICCKTGM
SYHELDERLENDPNIIICWK
NT seq
1143 nt
NT seq
+upstream
nt +downstream
nt
atgggcagcggctgccgcatcgaatgcatattcttcagcgagttccaccccacgctggga
cccaagatcacctatcaggtccctgaagacttcatctcccgagagctgtttgacacagtc
caagtgtacatcatcaccaagccagagctgcagaacaagcttatcactgtcacagctatg
gaaaagaagctgatcggctgtcctgtgtgcatcgaacacaagaagtacagccgcaatgct
ctcctcttcaacctgggcttcgtgtgtgatgcccaggccaagacctgcgccctcgagccc
attgttaaaaagctggctggctatctgaccacactagagctagagagcagcttcgtgtcc
atggaggagagcaagcagaagttggtgcccatcatgaccatcttgctggaggagctaaat
gcctcaggccggtgcactctgcccattgatgagtccaacaccatccacttgaaggtgatt
gagcagcggccagaccctccggtggcccaggagtatgatgtacctgtctttaccaaagac
aaggaggatttcttcaactcacagtgggacctcactacacaacaaatcctgccctacatt
gatgggttccgccacatccagaagatttcagcagaggcagatgtggagctcaacctggtg
cgcattgctatccagaacctgctgtactacggcgttgtgacactggtgtccatcctccag
tactccaatgtatactgcccaacgcccaaggtccaggacctggtagatgacaagtccctg
caagaggcatgtctatcctacgtgaccaagcaagggcacaagagggccagtctccgggat
gtgttccagctatactgcagcctgagccctggcactaccgtgcgagacctcattggccgc
cacccccagcagctgcagcatgttgatgaacggaagctgatccagttcgggcttatgaag
aacctcatcaggcgactacagaagtatcctgtgcgggtgactcgggaagagcagagccac
cctgcccggctttatacaggctgccacagctatgacgagatctgctgcaagacaggcatg
agctaccatgagctggatgagcggcttgaaaatgaccccaacatcatcatctgctggaag
tga
Homo sapiens (human): 8131
Help
Entry
8131 CDS
T01001
Symbol
NPRL3, C16orf35, CGTHBA, FFEVF3, HS-40, MARE, NPR3, RMD11
Name
(RefSeq) NPR3 like, GATOR1 complex subunit
KO
K20406
nitrogen permease regulator 3
Organism
hsa
Homo sapiens (human)
Pathway
hsa04150
mTOR signaling pathway
Network
nt06522
mTOR signaling
Element
N01578
GATOR1-mTORC1 signaling pathway
Disease
H02214
Familial focal epilepsy with variable foci
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04150 mTOR signaling pathway
8131 (NPRL3)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
8131 (NPRL3)
Membrane trafficking [BR:
hsa04131
]
Autophagy
Other autophagy associated proteins
SEACIT/GATOR1 complex
8131 (NPRL3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NPR3
HTH_NPRL3
NPR2
Motif
Other DBs
NCBI-GeneID:
8131
NCBI-ProteinID:
NP_001070818
OMIM:
600928
HGNC:
14124
Ensembl:
ENSG00000103148
UniProt:
Q12980
Q9BTE2
Structure
PDB
PDBj
LinkDB
All DBs
Position
16:complement(85386..138673)
Genome browser
AA seq
569 aa
AA seq
DB search
MRDNTSPISVILVSSGSRGNKLLFRYPFQRSQEHPASQTSKPRSRYAASNTGDHADEQDG
DSRFSDVILATILATKSEMCGQKFELKIDNVRFVGHPTLLQHALGQISKTDPSPKREAPT
MILFNVVFALRANADPSVINCLHNLSRRIATVLQHEERRCQYLTREAKLILALQDEVSAM
ADGNEGPQSPFHHILPKCKLARDLKEAYDSLCTSGVVRLHINSWLEVSFCLPHKIHYAAS
SLIPPEAIERSLKAIRPYHALLLLSDEKSLLGELPIDCSPALVRVIKTTSAVKNLQQLAQ
DADLALLQVFQLAAHLVYWGKAIIIYPLCENNVYMLSPNASVCLYSPLAEQFSHQFPSHD
LPSVLAKFSLPVSLSEFRNPLAPAVQETQLIQMVVWMLQRRLLIQLHTYVCLMASPSEEE
PRPREDDVPFTARVGGRSLSTPNALSFGSPTSSDDMTLTSPSMDNSSAELLPSGDSPLNQ
RMTENLLASLSEHERAAILSVPAAQNPEDLRMFARLLHYFRGRHHLEEIMYNENTRRSQL
LMLFDKFRSVLVVTTHEDPVIAVFQALLP
NT seq
1710 nt
NT seq
+upstream
nt +downstream
nt
atgcgggacaacaccagccccatcagcgtgattctggtgagctcggggagcaggggcaat
aagctgctgttcaggtaccccttccagagaagccaggagcacccggcgtcccagacaagt
aagccgcgtagcagatacgctgccagcaacacgggcgaccatgctgatgagcaggacggc
gattccaggttttcagatgttattctggcaacaattttggcaaccaagtctgaaatgtgt
ggccaaaaatttgaactgaagattgataatgtgcgatttgttgggcacccaacactgcta
cagcatgctctggggcagatctccaaaacagatccttccccgaagagggaagcacctact
atgattctttttaatgtggtgtttgcactgagggccaacgcagacccgtcagtgataaac
tgtctgcataacctgtcccgtcgtatcgccaccgtgctgcagcacgaggagcgccgctgc
cagtacctcacccgggaggccaagctgatcctggcgctccaggatgaggtgtccgccatg
gctgatggaaatgaaggtcctcagtccccattccatcacatcctgcccaagtgcaagctg
gccagggacctcaaggaagcttatgacagcctgtgcacgtcgggcgtagttcggcttcac
atcaacagctggctggaggtgagcttctgcctgccccacaagatccactatgcggcctcc
agtctgatccccccagaggccatcgaacggagcctgaaagccatccgcccctaccatgcc
ctgctgctgctcagtgatgagaagtccttgctgggtgagcttcctattgactgctcccct
gccctagtgcgggtgatcaagaccacatctgctgtgaagaacctgcagcagctagcccaa
gatgcggacctggccttgctgcaggttttccagcttgcagctcatctggtgtactggggc
aaggccatcatcatctacccgctgtgtgagaacaacgtctacatgctgtctcccaatgcc
agcgtatgtctgtactccccgctggccgagcagttctcccaccagttcccatctcatgac
ctgccgtccgttcttgccaagttctccttgccggtctccttgtcagaatttaggaatccc
ctggcccccgctgtgcaggagacccagctcatccagatggtggtgtggatgctgcagcgc
cggcttctcatccagctgcacacctatgtctgcctgatggcctcacccagcgaggaggag
ccccgtccgcgagaggacgacgtccccttcactgcccgggtcggcggtcgcagcctcagc
acgcccaacgccctcagctttggctccccaaccagcagcgatgacatgaccctcaccagc
cccagcatggacaactccagcgcagagctacttcccagcggggactcgccactgaaccag
aggatgacggagaacctgctggccagcctgtcggagcatgaacgcgcagccatcctcagt
gtacccgcagcccagaaccctgaggacctccgcatgtttgccaggctccttcactacttc
cgcggccgccaccacctggaggagattatgtacaacgagaacacgcggcgctcccagctg
ctcatgctgtttgacaagttccgcagcgtgctggtggtgaccacccacgaggaccctgtc
attgccgtcttccaggctctgctcccctga
Homo sapiens (human): 9681
Help
Entry
9681 CDS
T01001
Symbol
DEPDC5, DEE111, DEP.5, FFEVF, FFEVF1, FPEVF
Name
(RefSeq) DEP domain containing 5, GATOR1 subcomplex subunit
KO
K20404
SEA/GATOR complex protein SEA1/DEPDC5
Organism
hsa
Homo sapiens (human)
Pathway
hsa04150
mTOR signaling pathway
Network
nt06522
mTOR signaling
Element
N01578
GATOR1-mTORC1 signaling pathway
Disease
H00606
Early infantile epileptic encephalopathy
H02214
Familial focal epilepsy with variable foci
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04150 mTOR signaling pathway
9681 (DEPDC5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
9681 (DEPDC5)
Membrane trafficking [BR:
hsa04131
]
Autophagy
Other autophagy associated proteins
SEACIT/GATOR1 complex
9681 (DEPDC5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DEPDC5_CTD
IML1
IML1_N
DEP
FGGY_N
Motif
Other DBs
NCBI-GeneID:
9681
NCBI-ProteinID:
NP_001229825
OMIM:
614191
HGNC:
18423
Ensembl:
ENSG00000100150
UniProt:
O75140
Structure
PDB
PDBj
LinkDB
All DBs
Position
22:31753968..31908033
Genome browser
AA seq
1603 aa
AA seq
DB search
MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE
DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS
LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA
SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST
SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT
PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT
CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP
FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE
LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
PDPILTLSAPPVVPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPE
ADIDRRDEDGVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGL
VSRNRPEEEDQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSE
FVSCWVEFSHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRIT
EGEAHCDIYGDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGP
ISTHSLESTAPPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTP
TYMDSPRKDGAFFMEFVRSPRTASSAFYPQVSVDQTATPMLDGTSLGICTGQSMDRGNSQ
TFGNSQNIGEQGYSSTNSSDSSSQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGL
SPYCFISAEVVHWLVNHVEGIQTQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKI
VTDKEPDRVAMQQPATTWHTAGVDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRP
ASYASRHSSFSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSL
NAAFEIKLHWMAVTAAVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLF
IPLNISCLLKEGSEHLFDSFEPETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKP
QYIHVTGTVFLQLPYSKRKFSGQQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRS
SATGDEKFADRLLKDFTDFCINRDNRLVTFWTSCLEKMHASAP
NT seq
4812 nt
NT seq
+upstream
nt +downstream
nt
atgagaacaacaaaggtctacaaactcgtcatccacaagaagggctttgggggcagtgat
gatgagctagttgtgaaccccaaagtgttccctcacatcaagcttggagacattgtagag
attgcacaccccaacgatgaatacagccctctgcttttgcaggtcaagtctcttaaggaa
gatttacagaaggaaactatcagtgtggaccagactgtgactcaagtgttccggctgaga
ccttatcaggatgtctatgttaatgtcgtagaccctaaggatgtgacccttgacctagtg
gaattaacttttaaggatcagtatattggccgtggggatatgtggcgactaaagaaaagt
ttggtcagcacatgtgcctatatcacccagaaggtggagtttgctggcatcagagcacag
gctggtgaactgtgggttaagaatgagaaggtcatgtgtggctacatcagtgaagatacc
agggtggtgtttcgttctacgtcggctatggtttacatatttattcagatgagctgtgaa
atgtgggattttgatatttatggggatttgtattttgagaaagctgtgaatggtttcctt
gctgatctatttaccaagtggaaggagaagaactgtagtcatgaagtgacagtggtcctg
ttttctagaactttctatgatgcaaaatctgttgatgaatttcctgaaataaaccgagcc
tcaattcgacaggatcacaaggggagattctatgaagacttttacaaagtggtggtgcag
aatgagagaagagaagaatggacttcacttctcgtaaccattaaaaaactcttcatccag
tatccagtgttggtgcgactggaacaggcagagggctttcctcaaggagataattctacc
tcagcacaaggaaactacctggaggccatcaatctgtcattcaatgtgtttgataagcac
tacatcaaccgcaactttgaccgaactgggcagatgtcagtggtgatcacgcccggggtg
ggtgtctttgaagtggaccgcctactcatgatcctgaccaagcagcggatgatagataat
ggaattggtgtggatttggtgtgcatgggagagcaaccgttacatgctgtcccattgttc
aagctccataatcggagtgctccccgtgattctcgtctgggcgatgactataatatccct
cactggataaaccacagtttctacacatccaaaagccagctcttttgtaatagtttcacc
ccacgaataaaactggcaggaaagaagcccgcctctgagaaagcaaaaaatggccgtgat
acatctctcgggagtccaaaagaatctgagaacgcccttcccatccaagtagattatgac
gcctatgacgctcaagtgttcaggctgcccggcccatcccgggcccagtgcctcaccacc
tgcagatctgtgcgagagcgagagagtcacagtcgaaagagtgccagctcctgtgatgtt
tcatccagcccttccctaccaagccgcacactgcccactgaggaagtgaggagccaggct
tctgacgacagctccctaggcaagagtgccaacatcctgatgatcccacacccccacctg
caccagtatgaagtcagcagctccttgggatacaccagcactcgagatgtcctggagaac
atgatggagccaccacagcgagactccagtgcaccagggaggtttcacgttggcagtgca
gaatccatgctgcatgttcgacctggtggatacacgccccagagagcactgattaacccc
ttcgctccctctcggatgcccatgaagcttacgtccaacagaaggcgctggatgcacact
tttcctgtggggccatccggagaagccatccagatccaccaccagacccgacagaatatg
gcggagctacaaggcagcgggcagagggatccaactcactcctctgcagagctgctggag
ttagcatatcatgaagctgctggaaggcacagcaattcccgccagcctggtgacggcatg
tccttcttgaacttcagtggaacagaggagctttctgtcggcctgcttagcaacagtggt
gcaggtatgaatcctaggacccagaataaggattctctagaggacagtgtttctacctct
ccagacccaattctgacactgtctgctccccctgtagtgccaggcttctgttgcacagtt
ggagtggactggaagtctctcactactccggcgtgcctcccccttaccaccgactacttc
cctgaccgccagggcctgcagaatgactacacagagggctgttatgatctccttccagaa
gcagacatcgacaggagggacgaagatggtgtgcagatgacagcccagcaggtatttgaa
gagtttatttgccaacgtctcatgcagggctaccaaatcatagtgcagcccaagacacag
aaacccaatcctgctgtcccgcccccgctgagcagtagcccactctatagccgaggcctt
gtgtcccgaaaccgccctgaggaggaggaccagtattggctgagtatgggcagaacgttc
cacaaagtgacgctgaaggataagatgatcacagtgacgcgataccttcccaagtatcct
tatgaatctgcccagatccactacacctacagcctctgtccttcccactcagactcagag
ttcgtctcctgctgggtggaattctcccacgaacggctggaggagtacaagtggaattac
ttagatcagtatatctgttctgccggctctgaagacttcagcttaattgagtccctgaag
ttctggaggacccgcttcctgctgctgccagcctgtgtcaccgccaccaagcgcatcacg
gagggggaggcccactgcgacatctatggggacaggccccgtgcagacgaggacgagtgg
caactcctggatggttttgtccgctttgtggagggcttgaatcgcattcgcaggcggcat
cgctcggatcgcatgatgcggaaagggaccgccatgaaaggcttgcagatgactgggccc
atttccacgcattctctggagtcaactgcacccccagtggggaagaagggaacctcagct
ctctctgccctgttggagatggaggccagtcagaagtgcctgggagaacagcaggcagct
gtgcatggtgggaagagctccgcccagtcagccgagagcagcagcgttgccatgactccc
acctacatggacagcccacgaaaggacggggccttctttatggagtttgtccgcagccca
cgcacagcatcgtccgccttctaccctcaggtatctgtggaccaaacagccactcctatg
ttggacggcaccagtttgggcatatgcacaggccaatccatggacagaggcaacagccag
acctttgggaactcccagaacataggagaacagggctactcctccacaaactccagtgac
agcagctctcagcagctggtggcaagctccttgacctcatcctctaccctgacagagatc
ctggaagccatgaagcacccctcgacaggagtccagctgctctctgaacagaagggcctc
tcaccgtactgcttcatcagcgcggaggtggtacactggttggtgaaccacgtggagggg
atccagacacaggcgatggccattgacatcatgcagaaaatgctggaagagcagctcatc
acacatgcatctggcgaagcctggcggaccttcatctacggcttctatttctacaagata
gtaacggacaaagagcccgaccgagtggccatgcagcagcccgccaccacctggcacaca
gcaggagtggacgacttcgccagcttccagcgcaagtggtttgaggtggcctttgtggca
gaagagctcgtgcactctgagattcctgcctttctcctgccctggctgcctagccggcca
gcctcctatgcaagtaggcacagctcctttagccgaagttttggaggacggagccaggcg
gcagcacttttagctgccactgtcccagagcagaggactgtgaccctggatgttgacgtg
aacaaccgcacagaccggctggagtggtgcagctgttattaccatggcaacttttctctg
aatgcagcctttgagatcaagctgcactggatggcggtgaccgcagcagtactcttcgag
atggtccaaggttggcatcggaaagccacctcctgtggcttcttgttagtcccagttttg
gaggggccttttgcactgcccagttacctgtatggcgacccccttcgtgcccagctcttc
atcccactcaacatcagctgcttgctcaaggagggcagcgagcacctgtttgatagcttt
gaacccgaaacgtactgggatcgaatgcacctcttccaggaagccattgcacacaggttt
gggtttgtacaagataaatattctgcctctgcttttaacttccctgctgagaacaagcct
cagtatatccacgttacaggaacagtgtttctgcagctgccctactccaagcgcaagttc
tcagggcagcagcggcggcggcggaactccaccagctccaccaaccagaacatgttctgc
gaggagcgggtcggctacaactgggcctacaacaccatgctcaccaaaacatggcgctcc
agcgccacaggggatgaaaagtttgctgatcggctgctgaaggacttcacggacttctgc
atcaaccgtgacaaccggctggtcacgttctggacaagttgcctggagaagatgcatgcc
agtgccccgtga
DBGET
integrated database retrieval system
