Homo sapiens (human): 11069
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Entry
11069 CDS
T01001
Symbol
RAPGEF4, CAMP-GEFII, CGEF2, EPAC, EPAC_2, EPAC2, Nbla00496
Name
(RefSeq) Rap guanine nucleotide exchange factor 4
KO
K04351
Rap guanine nucleotide exchange factor 4
Organism
hsa
Homo sapiens (human)
Pathway
hsa04015
Rap1 signaling pathway
hsa04024
cAMP signaling pathway
hsa04072
Phospholipase D signaling pathway
hsa04081
Hormone signaling
hsa04261
Adrenergic signaling in cardiomyocytes
hsa04670
Leukocyte transendothelial migration
hsa04911
Insulin secretion
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
11069 (RAPGEF4)
04072 Phospholipase D signaling pathway
11069 (RAPGEF4)
04024 cAMP signaling pathway
11069 (RAPGEF4)
09133 Signaling molecules and interaction
04081 Hormone signaling
11069 (RAPGEF4)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
11069 (RAPGEF4)
09152 Endocrine system
04911 Insulin secretion
11069 (RAPGEF4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
11069 (RAPGEF4)
Membrane trafficking [BR:
hsa04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
Rab associated proteins
11069 (RAPGEF4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
cNMP_binding
DEP
RasGEF_N
RA_2
Motif
Other DBs
NCBI-GeneID:
11069
NCBI-ProteinID:
NP_008954
OMIM:
606058
HGNC:
16626
Ensembl:
ENSG00000091428
UniProt:
Q8WZA2
LinkDB
All DBs
Position
2:172735318..173052893
Genome browser
AA seq
1011 aa
AA seq
DB search
MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGY
YENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDN
TPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENT
PLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTE
LVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLP
TEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHL
STTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDD
FGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKV
PAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVF
MPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMA
FLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQK
RQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEK
VVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQM
TIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKR
VQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLM
DPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTART
VRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP
NT seq
3036 nt
NT seq
+upstream
nt +downstream
nt
atggtcgctgcgcacgctgcccattcttcctcctctgccgagtggatcgcctgcctggat
aaaagaccactggagcgatccagcgaagatgtggatataatcttcactcgactgaaagaa
gttaaagcttttgagaaatttcacccaaatctccttcatcagatttgcttatgtggttat
tatgagaatctggaaaagggaataacattatttcgccagggtgatattggaacaaactgg
tatgctgtcctggcagggtctttggatgttaaagtatctgagaccagcagtcaccaggat
gctgtgaccatctgtaccctgggaattgggacggcctttggagagtccattctggacaac
acaccccgccatgcaaccatcgttaccagggagagcagtgaactgctccgcatcgagcag
aaggacttcaaggcactatgggagaaatatcgacagtatatggcaggacttctggctcct
ccttatggtgttatggaaacgggctctaacaatgacaggattcctgacaaggagaacaca
cctctcattgaacctcacgttcctcttcgtcctgctaacaccattaccaaggtcccttca
gagaagatcctcagagctggaaaaattttacgaaatgccattctctctcgagcacctcac
atgataagagatagaaaataccacctaaagacatacagacaatgctgtgtgggaactgaa
ctggtggactggatgatgcagcagacaccatgtgttcactcccggactcaagctgttggc
atgtggcaagtcctgttagaagatggtgttctcaaccacgtggaccaggagcaccatttc
caagacaaatatttattctatcgatttctggatgatgagcacgaggatgcccctttgcct
actgaggaggagaagaaggagtgtgatgaggagctccaggacaccatgctgctgctgtca
cagatgggccccgacgcccacatgaggatgatccttcgcaaaccacctggccagaggact
gtggatgacctagagattatctatgaggagcttcttcatattaaagccttatcccatctt
tctaccacagtgaaacgagagttagcaggtgttctcatttttgagtctcacgccaaagga
gggactgtgttgtttaaccagggggaagaaggtacctcctggtacattattctaaaagga
tcagtgaatgtagtcatttacggcaagggtgtggtctgcaccctgcatgaaggagatgac
ttcggcaagttagcactagtgaatgatgccccacgagctgcctctatcgtcttacgagaa
gataactgccatttcttaagagtagacaaggaggatttcaaccggatcctaagggacgtg
gaggcgaatacagtcagacttaaagaacatgaccaagatgtcttggtgctggagaaggtc
ccagcagggaacagagcttctaatcaaggaaactcacagcctcagcaaaagtatactgtg
atgtcaggaacacctgaaaaaattttagagcattttctagaaacaatacgccttgaggca
actttaaatgaagcaacagattctgttttaaatgactttattatgatgcactgtgttttt
atgccaaatacccagctttgcccggcactggtggcccactaccacgcacagccttcacaa
ggtacagaacaggagaaaatggattatgccctcaacaataagaggcgagtcatccgcctg
gttctacagtgggctgccatgtatggagacctcctgcaagaggatgacgtgtctatggcc
ttcctggaggagttttatgtatctgtatcagatgatgcccggatgattgctgccctcaag
gagcaactgccagagttggagaagattgtcaagcaaatctcagaagatgcaaaggcacca
caaaagaagcacaaggttcttttgcaacagttcaatacgggcgatgagagagcccagaag
cgccagcctatccgcggctctgatgaagttctgtttaaggtctattgcatggaccacacc
tacacaaccattcgggtgccagtggccacttcggtgaaggaagtcatcagtgcagttgcc
gacaagctgggctccggggagggcctgatcatagtcaagatgagttccggaggagaaaag
gtggtgctcaaacctaatgatgtttcagtatttacgacgctcaccattaatggacgcctg
tttgcttgcccgcgagagcaattcgattcactgactcccttaccagaacaggaaggccca
actgttggaacagtgggaacttttgaactgatgagctccaaagatttagcataccagatg
acaatttatgattgggaactcttcaactgcgtgcatgagctggagctaatctatcacaca
tttggaaggcataattttaaaaagaccacagcaaacttggatttgttcctgaggagattt
aatgaaattcagttttgggtcgtcactgagatctgcctttgttctcagctcagcaagcgt
gttcagctattaaaaaaatttattaagatagcagcccactgtaaggagtataaaaatctg
aattccttttttgccatcgtcatgggactaagtaacgttgctgtgagccgcttggcacta
acgtgggagaaactgccaagcaagttcaagaagttctatgcggagtttgaaagtttaatg
gacccttcaaggaaccacagggcctacaggctgacagtagctaagctggaacctcctctc
atccccttcatgcctttgctcattaaagatatgacatttactcatgaggggaacaagacg
ttcattgacaatctagtaaactttgaaaaaatgcgcatgattgcaaatacggccagaaca
gtgagatactacaggagccaacccttcaatcctgatgcagctcaagctaataagaaccat
caggatgtccggagttatgtacggcaattaaatgtgattgacaaccagagaactttatca
cagatgtcacacagattagagcctcgtcgaccatag
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integrated database retrieval system
