KEGG   Homo sapiens (human): 112817
Entry
112817            CDS       T01001                                 
Symbol
HOGA1, C10orf65, DHDPS2, DHDPSL, HP3, NPL2
Name
(RefSeq) 4-hydroxy-2-oxoglutarate aldolase 1
  KO
K18123  4-hydroxy-2-oxoglutarate aldolase [EC:4.1.3.16]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00330  Arginine and proline metabolism
hsa00630  Glyoxylate and dicarboxylate metabolism
hsa01100  Metabolic pathways
Disease
H00117  Primary hyperoxaluria
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    112817 (HOGA1)
  09105 Amino acid metabolism
   00330 Arginine and proline metabolism
    112817 (HOGA1)
Enzymes [BR:hsa01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.3  Oxo-acid-lyases
    4.1.3.16  4-hydroxy-2-oxoglutarate aldolase
     112817 (HOGA1)
SSDB
Motif
Pfam: DHDPS
Other DBs
NCBI-GeneID: 112817
NCBI-ProteinID: NP_612422
OMIM: 613597
HGNC: 25155
Ensembl: ENSG00000241935
UniProt: Q86XE5
Structure
LinkDB
Position
10:97584389..97612802
AA seq 327 aa
MLGPQVWSSVRQGLSRSLSRNVGVWASGEGKKVDIAGIYPPVTTPFTATAEVDYGKLEEN
LHKLGTFPFRGFVVQGSNGEFPFLTSSERLEVVSRVRQAMPKNRLLLAGSGCESTQATVE
MTVSMAQVGADAAMVVTPCYYRGRMSSAALIHHYTKVADLSPIPVVLYSVPANTGLDLPV
DAVVTLSQHPNIVGMKDSGGDVTRIGLIVHKTRKQDFQVLAGSAGFLMASYALGAVGGVC
ALANVLGAQVCQLERLCCTGQWEDAQKLQHRLIEPNAAVTRRFGIPGLKKIMDWFGYYGG
PCRAPLQELSPAEEEALRMDFTSNGWL
NT seq 984 nt   +upstreamnt  +downstreamnt
atgctgggtccccaagtctggtcttctgtgaggcaggggctaagcaggagcttgtccagg
aatgtgggggtctgggcctcaggggaggggaagaaggtggacattgcgggtatctacccc
cctgtgaccacccccttcactgccactgcagaggtggactatgggaaactggaggagaat
ctgcacaaactgggcaccttccccttccgaggcttcgtggtccagggctccaatggcgag
tttcctttcctgaccagcagtgagcgcctcgaggtggtgagccgtgtgcgccaggccatg
cccaagaacaggctcctgctagctggctccggatgcgagtccactcaagccacagtggag
atgaccgtcagcatggcccaggtcggggctgacgcggccatggtggtgaccccttgctac
tatcgtggccgcatgagcagtgcggccctcattcaccactacaccaaggttgctgatctc
tctccaatccctgtggtgctgtacagtgtcccagccaacacagggctggacctgcctgtg
gatgcagtggtcacgctttcccagcacccgaatattgtgggcatgaaggacagcggtggt
gatgtgaccaggattgggctgattgttcacaagaccaggaagcaggattttcaggtgttg
gctggatcggctggctttctgatggccagctatgccttgggagctgtggggggcgtctgc
gccctggccaatgtcctgggggctcaggtgtgccagctggagcgactgtgctgcacgggg
caatgggaagatgcccagaaactgcagcaccgcctcattgagccaaacgctgcggtgacc
cggcgctttgggatcccagggctgaagaaaatcatggactggtttggctactatggaggc
ccctgccgcgcccccttgcaggagctgagccccgctgaggaggaggcactgcgcatggat
ttcaccagcaacggctggctctga

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