Homo sapiens (human): 11340
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Entry
11340 CDS
T01001
Symbol
EXOSC8, CIP3, EAP2, OIP2, PCH1C, RRP43, Rrp43p, bA421P11.3, p9
Name
(RefSeq) exosome component 8
KO
K12586
exosome complex component RRP43
Organism
hsa
Homo sapiens (human)
Pathway
hsa03018
RNA degradation
Disease
H00897
Pontocerebellar hypoplasia
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03018 RNA degradation
11340 (EXOSC8)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
hsa03019
]
11340 (EXOSC8)
Messenger RNA biogenesis [BR:
hsa03019
]
Eukaryotic type
mRNA degradation factors
3'-5' decay
Core exosome factors
11340 (EXOSC8)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RNase_PH
RNase_PH_C
Motif
Other DBs
NCBI-GeneID:
11340
NCBI-ProteinID:
NP_852480
OMIM:
606019
HGNC:
17035
Ensembl:
ENSG00000120699
UniProt:
Q96B26
Structure
PDB
PDBj
LinkDB
All DBs
Position
13:37000786..37009614
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AA seq
276 aa
AA seq
DB search
MAAGFKTVEPLEYYRRFLKENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVIC
GVKAEFAAPSTDAPDKGYVVPNVDLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQ
KEDLCISPGKLVWVLYCDLICLDYDGNILDACTFALLAALKNVQLPEVTINEETALAEVN
LKKKSYLNIRTHPVATSFAVFDDTLLIVDPTGEEEHLATGTLTIVMDEEGKLCCLHKPGG
SGLTGAKLQDCMSRAVTRHKEVKKLMDEVIKSMKPK
NT seq
831 nt
NT seq
+upstream
nt +downstream
nt
atggcggctgggttcaaaaccgtggaacctctggagtattacaggagatttctgaaagag
aactgccgtcctgatggaagagaacttggtgaattcagaaccacaactgtcaacatcggt
tcaattagtaccgcagatggttctgctttagtgaagttgggaaatactacagtaatctgt
ggagttaaagcagaatttgcagcaccatcaacagatgcccctgataaaggatacgttgtt
cctaatgtggatctaccacccctgtgttcatcgagattccggtctggacctcctggagaa
gaggcccaagtggctagccagttcattgcagatgtcattgaaaattcacagataattcag
aaagaggacttatgcatttctccaggaaagcttgtctgggttctatactgtgatctcatt
tgcctcgactacgatggaaacattttggatgcctgcacatttgctttgctagcggcttta
aaaaatgtacagttgcctgaagttactataaatgaagaaactgctttagcagaagttaat
ttaaagaagaaaagttatttgaatattagaactcatccagttgcaacttcctttgctgtg
tttgatgacactttgcttatagttgaccctactggagaggaggaacatctggcaacagga
accttaacaatagtaatggatgaggaaggcaaactctgttgtcttcacaaaccaggtgga
agtgggctaactggagctaaacttcaggactgtatgagccgagcagttacaagacacaaa
gaagttaaaaaactgatggatgaagtaattaagagtatgaaacccaaataa
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