Homo sapiens (human): 115201 Help Entry 115201            CDS       T01001                                  Symbol ATG4A, APG4A, AUTL2, HsAPG4A Name (RefSeq) autophagy related 4A cysteine peptidase   KO K08342   cysteine protease ATG4 [EC:3.4.22.-] Organism hsa  Homo sapiens (human) Pathway hsa04136   Autophagy - other hsa04140   Autophagy - animal Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     115201 (ATG4A)    04136 Autophagy - other     115201 (ATG4A)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:hsa01002]     115201 (ATG4A)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     115201 (ATG4A)    03029 Mitochondrial biogenesis [BR:hsa03029]     115201 (ATG4A) Enzymes [BR:hsa01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.-      115201 (ATG4A) Peptidases and inhibitors [BR:hsa01002]  Cysteine peptidases   Family C54: Aut2 peptidase family    115201 (ATG4A) Membrane trafficking [BR:hsa04131]  Autophagy   Autophagosome formation proteins    Atg8 conjugation proteins     115201 (ATG4A) Mitochondrial biogenesis [BR:hsa03029]  Mitochondrial quality control factors   Mitophagy factors    Autophagy-related proteins     115201 (ATG4A) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C54 ATG4_LIR Motif Other DBs NCBI-GeneID:  115201 NCBI-ProteinID:  NP_443168 OMIM:  300663 HGNC:  16489 Ensembl:  ENSG00000101844 Pharos:  Q8WYN0(Tbio) UniProt:  Q8WYN0 Structure PDB LinkDB All DBs Position X:108088829..108154671 Genome browser AA seq 398 aa AA seqDB search MESVLSKYEDQITIFTDYLEEYPDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRK FSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWSWEKQKEQPKEYQRILQCFLD RKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSLAVYVSMDNTVVIE DIKKMCRVLPLSADTAGDRPPDSLTASNQSKGTSAYCSAWKPLLLIVPLRLGINQINPVY VDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDTEENGTVNDQTF HCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLRMFELVQKHPSHWP PFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSV NT seq 1197 nt NT seq  +upstreamnt  +downstreamnt atggagtcagttttatccaagtatgaagatcagattactattttcactgactacctagaa gaatatccagatacagatgagctggtatggatcttagggaagcagcatctccttaaaaca gaaaaatctaagctgttgtctgatataagtgctcgtctatggtttacatacagaaggaaa ttttcaccaattggtggaacgggcccttcatcagatgctggttggggatgtatgctacgc tgtggacagatgatgctggctcaagcccttatctgtagacacttgggaagggactggagc tgggagaaacaaaaagaacaacccaaagaataccaacgcatcctacagtgcttcttagat agaaaagattgttgctactctatccatcaaatggcacaaatgggtgtaggagaagggaaa tcaattggagaatggtttggaccaaatacagttgcacaggtgttaaaaaaacttgcttta tttgacgaatggaattccttggctgtttatgtttcaatggataacacagtggtcattgaa gatatcaaaaaaatgtgccgtgtccttcccttgagtgctgacacagctggtgacaggcct cccgattctttaactgcttcaaaccagagtaagggcacctctgcctactgctcagcctgg aaacccctgctgctcattgtgccccttcgcctgggcataaaccaaatcaatcctgtctat gttgatgcattcaaagagtgttttaagatgccacagtctttaggggcattaggaggaaaa ccaaataacgcgtattatttcataggattcttaggtgacgagctcatcttcttggaccct catacaacccagacctttgttgacactgaagagaatggaacggttaatgaccagactttc cattgcctgcagtccccacagcgaatgaacatcctaaacctggatccttcagttgcattg ggatttttctgcaaagaagaaaaagactttgataactggtgtagccttgttcagaaggaa attctaaaggagaatttaaggatgtttgaattagttcagaaacatccatcacactggcct ccctttgtacctccagccaagccagaagtgacaaccactggggcagaattcattgactct actgagcaactggaggagtttgatctggaggaagattttgagattctgagtgtgtag

Homo sapiens (human): 23192 Help Entry 23192             CDS       T01001                                  Symbol ATG4B, APG4B, AUTL1, HsAPG4B Name (RefSeq) autophagy related 4B cysteine peptidase   KO K08342   cysteine protease ATG4 [EC:3.4.22.-] Organism hsa  Homo sapiens (human) Pathway hsa04136   Autophagy - other hsa04140   Autophagy - animal Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     23192 (ATG4B)    04136 Autophagy - other     23192 (ATG4B)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:hsa01002]     23192 (ATG4B)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     23192 (ATG4B)    03029 Mitochondrial biogenesis [BR:hsa03029]     23192 (ATG4B) Enzymes [BR:hsa01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.-      23192 (ATG4B) Peptidases and inhibitors [BR:hsa01002]  Cysteine peptidases   Family C54: Aut2 peptidase family    23192 (ATG4B) Membrane trafficking [BR:hsa04131]  Autophagy   Autophagosome formation proteins    Atg8 conjugation proteins     23192 (ATG4B) Mitochondrial biogenesis [BR:hsa03029]  Mitochondrial quality control factors   Mitophagy factors    Autophagy-related proteins     23192 (ATG4B) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C54 ATG4_LIR Motif Other DBs NCBI-GeneID:  23192 NCBI-ProteinID:  NP_037457 OMIM:  611338 HGNC:  20790 Ensembl:  ENSG00000168397 Pharos:  Q9Y4P1(Tbio) UniProt:  Q9Y4P1 B3KVU2 Structure PDB LinkDB All DBs Position 2:241637693..241673857 Genome browser AA seq 393 aa AA seqDB search MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPA IGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKD SYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIR RLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYV ETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFH CQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQPSHLA CPDVLNLSLDSSDVERLERFFDSEDEDFEILSL NT seq 1182 nt NT seq  +upstreamnt  +downstreamnt atggacgcagctactctgacctacgacactctccggtttgctgagtttgaagattttcct gagacctcagagcccgtttggatactgggtagaaaatacagcattttcacagaaaaggac gagatcttgtctgatgtggcatctagactttggtttacatacaggaaaaactttccagcc attggggggacaggccccacctcggacacaggctggggctgcatgctgcggtgtggacag atgatctttgcccaagccctggtgtgccggcacctaggccgagattggaggtggacacaa aggaagaggcagccagacagctacttcagcgtcctcaacgcattcatcgacaggaaggac agttactactccattcaccagatagcgcaaatgggagttggcgaaggcaagtccataggc cagtggtacgggcccaacactgtcgcccaggtcctgaagaagcttgctgtcttcgatacg tggagctccttggcggtccacattgcaatggacaacactgttgtgatggaggaaatcaga aggttgtgcaggaccagcgttccctgtgcaggcgccactgcgtttcctgcagattccgac cggcactgcaacggattccctgccggagctgaggtcaccaacaggccgtcgccatggaga cccctggtacttctcattcccctgcgcctggggctcacggacatcaacgaggcctacgtg gagacgctgaagcactgcttcatgatgccccagtccctgggcgtcatcggagggaagccc aacagcgcccactacttcatcggctacgttggtgaggagctcatctacctggacccccac accacgcagccagccgtggagcccactgatggctgcttcatcccggacgagagcttccac tgccagcacccgccgtgccgcatgagcatcgcggagcttgacccgtccatcgctgtgggg tttttctgtaagactgaagatgacttcaatgattggtgccagcaagtcaaaaagctgtct ctgcttggaggtgccctgcccatgtttgagctggtggagctgcagccttcacatctggcc tgccccgacgtcctgaacctgtccctagattcttctgatgtagagcgactggaaagattc ttcgactcagaagatgaagactttgaaatcctgtccctttga

Homo sapiens (human): 84938 Help Entry 84938             CDS       T01001                                  Symbol ATG4C, APG4-C, APG4C, AUTL1, AUTL3, HsAPG4C Name (RefSeq) autophagy related 4C cysteine peptidase   KO K08342   cysteine protease ATG4 [EC:3.4.22.-] Organism hsa  Homo sapiens (human) Pathway hsa04136   Autophagy - other hsa04140   Autophagy - animal Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     84938 (ATG4C)    04136 Autophagy - other     84938 (ATG4C)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:hsa01002]     84938 (ATG4C)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     84938 (ATG4C)    03029 Mitochondrial biogenesis [BR:hsa03029]     84938 (ATG4C) Enzymes [BR:hsa01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.-      84938 (ATG4C) Peptidases and inhibitors [BR:hsa01002]  Cysteine peptidases   Family C54: Aut2 peptidase family    84938 (ATG4C) Membrane trafficking [BR:hsa04131]  Autophagy   Autophagosome formation proteins    Atg8 conjugation proteins     84938 (ATG4C) Mitochondrial biogenesis [BR:hsa03029]  Mitochondrial quality control factors   Mitophagy factors    Autophagy-related proteins     84938 (ATG4C) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C54 ATG4_LIR Motif Other DBs NCBI-GeneID:  84938 NCBI-ProteinID:  NP_116241 OMIM:  611339 HGNC:  16040 Ensembl:  ENSG00000125703 Pharos:  Q96DT6(Tbio) UniProt:  Q96DT6 A0A384MTY5 LinkDB All DBs Position 1:62784132..62865516 Genome browser AA seq 458 aa AA seqDB search MEATGTDEVDKLKTKFISAWNNMKYSWVLKTKTYFSRNSPVLLLGKCYHFKYEDEDKTLP AESGCTIEDHVIAGNVEEFRKDFISRIWLTYREEFPQIEGSALTTDCGWGCTLRTGQMLL AQGLILHFLGRAWTWPDALNIENSDSESWTSHTVKKFTASFEASLSGEREFKTPTISLKE TIGKYSDDHEMRNEVYHRKIISWFGDSPLALFGLHQLIEYGKKSGKKAGDWYGPAVVAHI LRKAVEEARHPDLQGITIYVAQDCTVYNSDVIDKQSASMTSDNADDKAVIILVPVRLGGE RTNTDYLEFVKGILSLEYCVGIIGGKPKQSYYFAGFQDDSLIYMDPHYCQSFVDVSIKDF PLETFHCPSPKKMSFRKMDPSCTIGFYCRNVQDFKRASEEITKMLKFSSKEKYPLFTFVN GHSRDYDFTSTTTNEEDLFSEDEKKQLKRFSTEEFVLL NT seq 1377 nt NT seq  +upstreamnt  +downstreamnt atggaggctacaggaacagatgaagttgacaagctaaaaaccaaatttatatctgcttgg aacaacatgaaatatagttgggtgttgaaaacaaagacgtattttagtagaaattctcct gtattattgcttggaaaatgttaccattttaaatatgaagatgaagataaaacgttacct gcagagtcgggatgtacaatagaggatcacgtaattgcaggaaatgtagaagaatttcgt aaagatttcatttctagaatatggctgacctacagggaagaattccctcaaatagaaggc tcagctttgacaacagactgtgggtggggctgcacattgagaactggccagatgctcttg gctcaaggactcatactacactttcttggtagagcttggacctggcctgatgctttgaat attgaaaattcagactctgaatcatggacttcccacactgtcaaaaaatttactgcatca tttgaagcatcactttcaggggaaagagaattcaaaaccccaacaatttctctgaaggaa acaattgggaaatattctgatgatcatgaaatgcgaaatgaagtttatcataggaaaatc atctcttggtttggtgattcccccttggctctttttggcttacatcaactaatagaatat ggaaagaagtctgggaaaaaagcaggagattggtatggaccagctgtggttgctcacatt ttaagaaaagcagttgaagaagcaaggcatcctgatttacaaggaataactatttatgtt gcacaagattgtacagtttacaattctgatgtaattgataaacagagtgcttccatgact tctgataatgcagatgacaaagctgttattattctagttcctgttagacttggtggagaa agaaccaacaccgactacttagaatttgtgaagggtattttaagcctggaatattgtgtg ggtattattggtggcaaacctaaacagtcatattactttgctggatttcaagatgacagt ttgatttacatggatcctcattactgccaatcttttgtagatgtcagcataaaggatttc cctcttgagacattccactgcccttctcccaaaaagatgtcttttcgaaaaatggatccc agctgtacaataggattttactgtcgaaatgttcaggacttcaaacgagcttctgaagaa atcaccaagatgctgaaattttcttctaaggagaaatatcccttatttacttttgtaaat ggtcattccagagactatgattttacatctactacaaccaatgaagaagaccttttttca gaggatgaaaagaaacaattaaaaagatttagcacggaagagtttgtcttgctttaa

Homo sapiens (human): 84971 Help Entry 84971             CDS       T01001                                  Symbol ATG4D, APG4-D, APG4D, AUTL4, HsAPG4D Name (RefSeq) autophagy related 4D cysteine peptidase   KO K08342   cysteine protease ATG4 [EC:3.4.22.-] Organism hsa  Homo sapiens (human) Pathway hsa04136   Autophagy - other hsa04140   Autophagy - animal Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     84971 (ATG4D)    04136 Autophagy - other     84971 (ATG4D)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:hsa01002]     84971 (ATG4D)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     84971 (ATG4D)    03029 Mitochondrial biogenesis [BR:hsa03029]     84971 (ATG4D) Enzymes [BR:hsa01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.-      84971 (ATG4D) Peptidases and inhibitors [BR:hsa01002]  Cysteine peptidases   Family C54: Aut2 peptidase family    84971 (ATG4D) Membrane trafficking [BR:hsa04131]  Autophagy   Autophagosome formation proteins    Atg8 conjugation proteins     84971 (ATG4D) Mitochondrial biogenesis [BR:hsa03029]  Mitochondrial quality control factors   Mitophagy factors    Autophagy-related proteins     84971 (ATG4D) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C54 Motif Other DBs NCBI-GeneID:  84971 NCBI-ProteinID:  NP_116274 OMIM:  611340 HGNC:  20789 Ensembl:  ENSG00000130734 Pharos:  Q86TL0(Tbio) UniProt:  Q86TL0 LinkDB All DBs Position 19:10543904..10553418 Genome browser AA seq 474 aa AA seqDB search MNSVSPAAAQYRSSSPEDARRRPEARRPRGPRGPDPNGLGPSGASGPALGSPGAGPSEPD EVDKFKAKFLTAWNNVKYGWVVKSRTSFSKISSIHLCGRRYRFEGEGDIQRFQRDFVSRL WLTYRRDFPPLPGGCLTSDCGWGCMLRSGQMMLAQGLLLHFLPRDWTWAEGMGLGPPELS GSASPSRYHGPARWMPPRWAQGAPELEQERRHRQIVSWFADHPRAPFGLHRLVELGQSSG KKAGDWYGPSLVAHILRKAVESCSDVTRLVVYVSQDCTVYKADVARLVARPDPTAEWKSV VILVPVRLGGETLNPVYVPCVKELLRCELCLGIMGGKPRHSLYFIGYQDDFLLYLDPHYC QPTVDVSQADFPLESFHCTSPRKMAFAKMDPSCTVGFYAGDRKEFETLCSELTRVLSSSS ATERYPMFTLAEGHAQDHSLDDLCSQLAQPTLRLPRTGRLLRAKRPSSEDFVFL NT seq 1425 nt NT seq  +upstreamnt  +downstreamnt atgaactcagtgtcgccggccgccgcgcagtaccggagcagcagcccggaggacgcgcgc cgccggcccgaggcccgcaggccgcggggtcccagaggcccagaccccaacggcctgggg ccttccggagccagcggccccgctcttggctctcccggggctggcccgagtgagccggac gaagtggacaagttcaaggccaagttcctgacagcctggaacaacgtcaagtacggttgg gtggttaaaagccggaccagctttagcaagatctccagcatccacctctgtggccgccgc taccgtttcgagggcgagggtgacatacagcgtttccagcgggactttgtgtcccgcctg tggctcacataccgccgggacttcccgccccttcctgggggctgcctgacctcggactgt ggctgggggtgcatgttacgcagcggccagatgatgctggcacagggccttctgctgcat ttcctgcccagagactggacatgggccgagggcatgggcctgggcccccctgagctgtca gggtcagcctctcccagccggtaccatgggcctgcccgctggatgcccccacgctgggcc cagggtgcccctgagctggagcaggaacgccggcaccggcagattgtgtcctggttcgcc gaccacccccgggccccctttggcctacaccggctggtggagcttgggcagagctcaggc aagaaggcaggtgactggtatgggccatcgctagtggcacacatcctcaggaaagccgtg gagagctgctccgacgtcacccgcctggtggtgtacgtttctcaggactgcacagtgtac aaggcggatgtggcacgcctggtggccaggccagaccccacagccgagtggaagtctgtg gtcatcctggtgcccgtgcgactgggtggcgagactctcaaccccgtgtatgtgccctgc gtgaaggaactcctgcgttgcgagctgtgcctgggcatcatgggtgggaaaccgcgacac tcactgtacttcattggctaccaagatgacttcctgctgtacctggaccctcactactgc cagcccactgtggatgtcagccaggccgacttccccctggagtccttccactgcacctcg ccccgcaagatggcctttgccaagatggacccaagctgtaccgtgggcttctatgctgga gacaggaaggagtttgagacactctgctcagagctgaccagggtcctcagctcctcctca gccacagagcggtaccccatgttcaccctggccgagggccatgctcaggaccacagcctg gacgacctctgctcccagctcgcccagcccacactccggctccctcgcacagggcggctc ctcagggccaaacgccccagctctgaggactttgtgtttttataa

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