Homo sapiens (human): 123745 Help Entry 123745            CDS       T01001                                  Symbol PLA2G4E Name (RefSeq) phospholipase A2 group IVE   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism hsa  Homo sapiens (human) Pathway hsa00564   Glycerophospholipid metabolism hsa00565   Ether lipid metabolism hsa00590   Arachidonic acid metabolism hsa00591   Linoleic acid metabolism hsa00592   alpha-Linolenic acid metabolism hsa01100   Metabolic pathways hsa04010   MAPK signaling pathway hsa04014   Ras signaling pathway hsa04072   Phospholipase D signaling pathway hsa04217   Necroptosis hsa04270   Vascular smooth muscle contraction hsa04370   VEGF signaling pathway hsa04611   Platelet activation hsa04664   Fc epsilon RI signaling pathway hsa04666   Fc gamma R-mediated phagocytosis hsa04724   Glutamatergic synapse hsa04726   Serotonergic synapse hsa04730   Long-term depression hsa04750   Inflammatory mediator regulation of TRP channels hsa04912   GnRH signaling pathway hsa04913   Ovarian steroidogenesis hsa04921   Oxytocin signaling pathway hsa05231   Choline metabolism in cancer Network nt06544  Neuroactive ligand signaling   Element N01900   Serotonin-HTR2-GNAQ/11 signaling pathway Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     123745 (PLA2G4E)    00565 Ether lipid metabolism     123745 (PLA2G4E)    00590 Arachidonic acid metabolism     123745 (PLA2G4E)    00591 Linoleic acid metabolism     123745 (PLA2G4E)    00592 alpha-Linolenic acid metabolism     123745 (PLA2G4E)  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     123745 (PLA2G4E)    04072 Phospholipase D signaling pathway     123745 (PLA2G4E)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     123745 (PLA2G4E)    04664 Fc epsilon RI signaling pathway     123745 (PLA2G4E)    04666 Fc gamma R-mediated phagocytosis     123745 (PLA2G4E)   09152 Endocrine system    04913 Ovarian steroidogenesis     123745 (PLA2G4E)    04921 Oxytocin signaling pathway     123745 (PLA2G4E)   09156 Nervous system    04724 Glutamatergic synapse     123745 (PLA2G4E)    04726 Serotonergic synapse     123745 (PLA2G4E)    04730 Long-term depression     123745 (PLA2G4E)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     123745 (PLA2G4E)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     123745 (PLA2G4E) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      123745 (PLA2G4E) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  cPLA2_C2 PLA2_B C2 Motif Other DBs NCBI-GeneID:  123745 NCBI-ProteinID:  NP_001193599 OMIM:  620649 HGNC:  24791 Ensembl:  ENSG00000188089 UniProt:  Q3MJ16 LinkDB All DBs Position 15:complement(41981582..42050703) Genome browser AA seq 868 aa AA seqDB search MSLQASEGCPGLGTNVFVPQSPQTDEEGSRSGRSFSEFEDTQDLDTPGLPPFCPMAPWGS EEGLSPCHLLTVRVIRMKNVRQADMLSQTDCFVSLWLPTASQKKLRTRTISNCPNPEWNE SFNFQIQSRVKNVLELSVCDEDTVTPDDHLLTVLYDLTKLCFRKKTHVKFPLNPQGMEEL EVEFLLEESPSPPETLVTNGVLVSRQVSCLEVHAQSRRRRKREKMKDLLVMVNESFENTQ RVRPCLEPCCPTSACFQTAACFHYPKYFQSQVHVEVPKSHWSCGLCCRSRKKGPISQPLD CLSDGQVMTLPVGESYELHMKSTPCPETLDVRLGFSLCPAELEFLQKRKVVVAKALKQVL QLEEDLQEDEVPLIAIMATGGGTRSMTSMYGHLLGLQKLNLLDCASYITGLSGATWTMAT LYRDPDWSSKNLEPAIFEARRHVVKDKLPSLFPDQLRKFQEELRQRSQEGYRVTFTDFWG LLIETCLGDERNECKLSDQRAALSCGQNPLPIYLTINVKDDVSNQDFREWFEFSPYEVGL QKYGAFIPSELFGSEFFMGRLVKRIPESRICYMLGLWSSIFSLNLLDAWNLSHTSEEFFH RWTREKVQDIEDEPILPEIPKCDANILETTVVIPGSWLSNSFREILTHRSFVSEFHNFLS GLQLHTNYLQNGQFSRWKDTVLDGFPNQLTESANHLCLLDTAFFVNSSYPPLLRPERKAD LIIHLNYCAGSQTKPLKQTCEYCTVQNIPFPKYELPDENENLKECYLMENPQEPDAPIVT FFPLINDTFRKYKAPGVERSPEELEQGQVDIYGPKTPYATKELTYTEATFDKLVKLSEYN ILNNKDTLLQALRLAVEKKKRLKGQCPS NT seq 2607 nt NT seq  +upstreamnt  +downstreamnt atgagtctccaggcctcggaaggctgtcctggcctgggaactaatgtgtttgtcccacag agcccacaaacggatgaagaaggcagcaggtcaggaagaagtttcagtgagttcgaggat acacaggacctggacactcctggtctcccacctttctgtcctatggctccttggggctct gaggaggggctgtctccatgccacctgttgacagtgagggtcatccggatgaaaaatgtc cggcaggctgatatgctgagccagacagactgttttgtgagcctctggctgcccaccgcc tctcagaagaagctgaggacaaggaccatctccaactgcccaaatccagagtggaatgaa agcttcaacttccagatccagagccgagtgaagaacgtgctagagttgagtgtctgtgat gaagacacagtgacaccagatgaccatctcctgacagttctctatgacctcaccaagctc tgtttccgaaagaaaacccacgtgaagtttccactcaacccgcagggcatggaagagctg gaggtggagttcctgctggaggagagtccctctccacctgagaccctcgtcaccaatggc gtgctggtgtctcgacaagtctcctgcctggaggttcatgcacaatccaggaggcggagg aagagggagaaaatgaaggacctcctggtgatggtgaacgaatcctttgagaacacccag cgtgtccggccctgcttggaaccctgctgcccaacctctgcctgcttccaaaccgctgcc tgcttccactaccccaagtacttccagtcccaggtgcacgtggaagtgcccaagagtcac tggagctgtgggctttgctgccgctctcgcaagaagggccccatcagccagcccctcgac tgcctttccgatggtcaggtgatgaccctgcctgtgggtgagagttatgaattacacatg aagtctacaccctgccctgagacactggacgtgcggctgggcttcagcctgtgcccagca gagctggagtttctgcagaagcggaaggtcgtggtggccaaggccctgaagcaggtgctg cagctggaggaagacctgcaggaggacgaggtgccgctgatagccatcatggccactggg ggtggaacaagatccatgacctccatgtatggccacctgctggggctgcagaagctgaac ctcctggactgtgccagctacatcaccggtctatcaggggccacctggaccatggctacc ttgtaccgtgaccctgactggtcctccaaaaacttggagcctgctatctttgaggctcgg agacatgtggtaaaggacaagctaccctccctgttcccagaccagctccgcaaattccag gaggagctccggcagcgcagccaggaaggctacagggtcacctttacagacttctggggc ctgctgatagagacctgcctgggggacgagagaaatgaatgcaaactgtcagatcagcgt gctgctttgagctgcggccagaaccccctgcccatctacctcaccatcaatgtcaaggat gatgtaagcaaccaggacttcagagagtggttcgagttctccccctacgaggtgggcctg cagaagtatggggccttcatcccctccgagctcttcggctccgagttcttcatggggcgg ctggtgaagaggatcccggagtctcgaatctgctacatgctaggcctgtggagcagcatc ttctccctgaacctgctggatgcctggaacctgtcacacacctcggaggagtttttccac aggtggacaagggagaaagtgcaggacatcgaagacgagccgatcctgcctgaaatcccc aaatgtgatgctaacatcctggagaccacggtagtgatcccagggtcatggctgtccaat tctttccgagaaatccttacccatcggtccttcgtgtctgagtttcacaacttcctgtct gggctgcagctgcacaccaactacctccagaatggccagttctctaggtggaaagacaca gtgctagatggtttcccaaaccagctgaccgagtccgcgaaccacctgtgcctgctggac actgcgttctttgtcaactccagctacccgcccctcctcaggccagagcgaaaagccgac ctcatcatccacctcaactactgtgctgggtcccagacaaagcccctgaaacaaacctgt gagtactgcactgtgcagaacatccccttccccaaatacgagctgccagatgagaatgaa aatctcaaggaatgctacctgatggagaacccccaggaacccgatgcccccatcgtgact ttcttcccactcatcaatgacactttccgaaaatacaaggcaccaggtgtagagcgaagc cctgaggagctggagcagggccaggtggacatttatggtcccaaaactccctatgccacc aaggagctgacatacacagaggccacctttgacaagctggtgaaactctcagagtataac atcctgaataataaggacactctcctccaggctctgcggctcgcagtggagaagaagaag cgcctgaagggccagtgtccctcctag

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