Homo sapiens (human): 130013
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Entry
130013 CDS
T01001
Symbol
ACMSD
Name
(RefSeq) aminocarboxymuconate semialdehyde decarboxylase
KO
K03392
aminocarboxymuconate-semialdehyde decarboxylase [EC:
4.1.1.45
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00380
Tryptophan metabolism
hsa01100
Metabolic pathways
Module
hsa_M00038
Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09105 Amino acid metabolism
00380 Tryptophan metabolism
130013 (ACMSD)
Enzymes [BR:
hsa01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.45 aminocarboxymuconate-semialdehyde decarboxylase
130013 (ACMSD)
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Motif
Pfam:
Amidohydro_2
DUF2963
Motif
Other DBs
NCBI-GeneID:
130013
NCBI-ProteinID:
NP_612199
OMIM:
608889
HGNC:
19288
Ensembl:
ENSG00000153086
UniProt:
Q8TDX5
Structure
PDB
PDBj
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All DBs
Position
2:134838616..134902034
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AA seq
336 aa
AA seq
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MKIDIHSHILPKEWPDLKKRFGYGGWVQLQHHSKGEAKLLKDGKVFRVVRENCWDPEVRI
REMDQKGVTVQALSTVPVMFSYWAKPEDTLNLCQLLNNDLASTVVSYPRRFVGLGTLPMQ
APELAVKEMERCVKELGFPGVQIGTHVNEWDLNAQELFPVYAAAERLKCSLFVHPWDMQM
DGRMAKYWLPWLVGMPAETTIAICSMIMGGVFEKFPKLKVCFAHGGGAFPFTVGRISHGF
SMRPDLCAQDNPMNPKKYLGSFYTDALVHDPLSLKLLTDVIGKDKVILGTDYPFPLGELE
PGKLIESMEEFDEETKNKLKAGNALAFLGLERKQFE
NT seq
1011 nt
NT seq
+upstream
nt +downstream
nt
atgaaaattgacatccatagtcatattctaccaaaagaatggccagatctaaaaaagagg
tttggctacggaggctgggtgcagctccaacaccacagcaagggagaagcaaagttgttg
aaagatgggaaagtcttcagagtggtgcgagagaattgctgggatccagaagttcgtatt
agagaaatggaccaaaaaggagtaacagtgcaagccctttccacagttcctgtcatgttt
agctactgggccaaacctgaggacactttaaacctgtgccagcttttaaacaacgacctt
gccagcaccgttgtgagctaccccaggaggttcgtgggtctggggacgttgcccatgcag
gcccctgagctggcggtcaaggagatggagcgctgtgtgaaagagctgggctttcccggg
gtccaaattggcacccacgtcaacgagtgggacctgaacgcgcaggagctctttcctgtc
tatgcggcagccgaaaggctgaagtgttccctgttcgtgcatccctgggacatgcagatg
gatggacgaatggccaaatactggctcccttggcttgtaggaatgccagcagagaccacc
atagccatttgctccatgatcatgggtggagtatttgagaagtttcccaaactgaaagtg
tgtttcgcacatggtggtggtgccttccccttcacagtgggaagaatctcccatggattc
agcatgcgcccagatctgtgtgcccaggacaaccccatgaacccgaagaaataccttggt
tccttttacacagatgctttggttcatgatcctctgtccctcaagctgttaacagatgtc
ataggaaaggataaagtcattttgggaaccgattacccctttccactaggtgagctggaa
cctgggaaactaatagagtccatggaagaatttgatgaagaaacaaagaataaactcaaa
gccggcaatgccctggcatttttgggtcttgagagaaaacaatttgaatga
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