| Entry |
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| Symbol |
COX10, MC4DN3
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| Name |
(RefSeq) cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10
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| KO |
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| Organism |
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| Pathway |
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| Module |
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| Network |
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| Element |
| N01691 | mitochondrial complex - UCP1 in Thermogenesis |
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| Disease |
| H01368 | Cytochrome c oxidase (COX) deficiency |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
1352 (COX10)
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
1352 (COX10)
09150 Organismal Systems
09159 Environmental adaptation
04714 Thermogenesis
1352 (COX10)
09180 Brite Hierarchies
09181 Protein families: metabolism
01006 Prenyltransferases [BR:hsa01006]
1352 (COX10)
09182 Protein families: genetic information processing
03029 Mitochondrial biogenesis [BR:hsa03029]
1352 (COX10)
Enzymes [BR:hsa01000]
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.141 heme o synthase
1352 (COX10)
Prenyltransferases [BR:hsa01006]
Compound prenylation
Protoheme farnesyltransferase
1352 (COX10)
Mitochondrial biogenesis [BR:hsa03029]
Mitochondrial quality control factors
Mitochondrial respiratory chain complex assembly factors
Complex-IV assembly factors
1352 (COX10)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
17:14069504..14208677
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| AA seq |
443 aa
MAASPHTLSSRLLTGCVGGSVWYLERRTIQDSPHKFLHLLRNVNKQWITFQHFSFLKRMY
VTQLNRSHNQQVRPKPEPVASPFLEKTSSGQAKAEIYEMRPLSPPSLSLSRKPNEKELIE
LEPDSVIEDSIDVGKETKEEKRWKEMKLQVYDLPGILARLSKIKLTALVVSTTAAGFALA
PGPFDWPCFLLTSVGTGLASCAANSINQFFEVPFDSNMNRTKNRPLVRGQISPLLAVSFA
TCCAVPGVAILTLGVNPLTGALGLFNIFLYTCCYTPLKRISIANTWVGAVVGAIPPVMGW
TAATGSLDAGAFLLGGILYSWQFPHFNALSWGLREDYSRGGYCMMSVTHPGLCRRVALRH
CLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRRSSRRLFFCSLWHLP
LLLLLMLTCKRPSGGGDAGPPPS |
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| NT seq |
1332 nt +upstreamnt +downstreamnt
atggccgcatctccgcacactctctcctcacgcctcctgacaggttgcgtaggaggctct
gtctggtatcttgaaagaagaactatacaggactcccctcacaagttcttacatcttctc
aggaatgtcaataagcagtggattacatttcagcactttagcttcctcaaacgcatgtat
gtcacacagctgaacagaagccacaaccagcaagtaagacccaagccagaaccagtagca
tctcctttccttgaaaaaacatcttcaggtcaagccaaagcagaaatatatgagatgaga
cctctctcaccgcccagcctatctttgtccagaaagccaaatgaaaaggaattgatagaa
ctagagccagactcagtaattgaagactcaatagatgtagggaaagagacaaaagaggaa
aagcggtggaaagagatgaagctgcaagtgtatgatttgccaggaattttggctcgacta
tccaaaatcaaactcacagctctggttgtaagtaccactgcagctggatttgcattggct
ccgggcccttttgactggccctgtttcctgcttacttctgttgggacaggccttgcatcc
tgtgctgccaactccatcaatcagttttttgaggtgccatttgactcaaacatgaatagg
acaaagaacagaccgctggttcgtggacagatcagcccattgctagctgtgtcctttgcc
acttgttgtgctgttccgggagttgccattctgaccttgggggtgaatccactcacagga
gccctggggctcttcaacattttcctgtatacctgctgctacacaccactgaaaaggatc
agcattgccaacacatgggtcggagctgtggttggggccatcccgcctgtcatgggctgg
acagcggccacgggcagcctcgatgctggcgcatttctcctgggaggaatcctctactcc
tggcagtttcctcatttcaacgccctgagctggggcctccgtgaagactactcccggggc
ggctactgcatgatgtcggtcacccacccgggcctgtgccggcgcgtggcgctgcgccac
tgcctggccctgctcgtgctgtccgcagcagcccctgtgctggacatcaccacatggacc
ttccccatcatggcccttcccatcaatgcgtacatctcctacctcggcttccgcttctac
gtggacgcagaccgcaggagctcgcggagactgttcttctgcagcctgtggcacctgccg
ctgctgctgctgctcatgctcacctgcaagcggccgagcggaggcggggacgcagggccc
cctcccagctga |
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