Homo sapiens (human): 1435
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Entry
1435 CDS
T01001
Symbol
CSF1, CSF-1, MCSF, PG-M-CSF
Name
(RefSeq) colony stimulating factor 1
KO
K05453
macrophage colony-stimulating factor 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04014
Ras signaling pathway
hsa04015
Rap1 signaling pathway
hsa04060
Cytokine-cytokine receptor interaction
hsa04061
Viral protein interaction with cytokine and cytokine receptor
hsa04151
PI3K-Akt signaling pathway
hsa04380
Osteoclast differentiation
hsa04640
Hematopoietic cell lineage
hsa04668
TNF signaling pathway
hsa05010
Alzheimer disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05323
Rheumatoid arthritis
Network
nt06526
MAPK signaling
nt06530
PI3K signaling
Element
N01592
GF-RTK-RAS-ERK signaling pathway
N01656
GF-RTK-PI3K signaling pathway
N01658
GF-RTK-RAS-PI3K signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
1435 (CSF1)
04015 Rap1 signaling pathway
1435 (CSF1)
04668 TNF signaling pathway
1435 (CSF1)
04151 PI3K-Akt signaling pathway
1435 (CSF1)
09133 Signaling molecules and interaction
04061 Viral protein interaction with cytokine and cytokine receptor
1435 (CSF1)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
1435 (CSF1)
09158 Development and regeneration
04380 Osteoclast differentiation
1435 (CSF1)
09160 Human Diseases
09163 Immune disease
05323 Rheumatoid arthritis
1435 (CSF1)
09164 Neurodegenerative disease
05010 Alzheimer disease
1435 (CSF1)
05022 Pathways of neurodegeneration - multiple diseases
1435 (CSF1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:
hsa04052
]
1435 (CSF1)
Cytokines and neuropeptides [BR:
hsa04052
]
Cytokines
CSF and other factors
1435 (CSF1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
CSF-1
Metal_resist
Motif
Other DBs
NCBI-GeneID:
1435
NCBI-ProteinID:
NP_000748
OMIM:
120420
HGNC:
2432
Ensembl:
ENSG00000184371
Pharos:
P09603
(Tbio)
UniProt:
P09603
Structure
PDB
PDBj
LinkDB
All DBs
Position
1:109910506..109930992
Genome browser
AA seq
554 aa
AA seq
DB search
MTAPGAAGRCPPTTWLGSLLLLVCLLASRSITEEVSEYCSHMIGSGHLQSLQRLIDSQME
TSCQITFEFVDQEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLK
SCFTKDYEEHDKACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSS
QDVVTKPDCNCLYPKAIPSSDPASVSPHQPLAPSMAPVAGLTWEDSEGTEGSSLLPGEQP
LHTVDPGSAKQRPPRSTCQSFEPPETPVVKDSTIGGSPQPRPSVGAFNPGMEDILDSAMG
TNWVPEEASGEASEIPVPQGTELSPSRPGGGSMQTEPARPSNFLSASSPLPASAKGQQPA
DVTGTALPRVGPVRPTGQDWNHTPQKTDHPSALLRDPPEPGSPRISSLRPQGLSNPSTLS
AQPQLSRSHSSGSVLPLGELEGRRSTRDRRSPAEPEGGPASEGAARPLPRFNSVPLTDTG
HERQSEGSFSPQLQESVFHLLVPSVILVLLAVGGLLFYRWRRRSHQEPQRADSPLEQPEG
SPLTQDDRQVELPV
NT seq
1665 nt
NT seq
+upstream
nt +downstream
nt
atgaccgcgccgggcgccgccgggcgctgccctcccacgacatggctgggctccctgctg
ttgttggtctgtctcctggcgagcaggagtatcaccgaggaggtgtcggagtactgtagc
cacatgattgggagtggacacctgcagtctctgcagcggctgattgacagtcagatggag
acctcgtgccaaattacatttgagtttgtagaccaggaacagttgaaagatccagtgtgc
taccttaagaaggcatttctcctggtacaagacataatggaggacaccatgcgcttcaga
gataacacccccaatgccatcgccattgtgcagctgcaggaactctctttgaggctgaag
agctgcttcaccaaggattatgaagagcatgacaaggcctgcgtccgaactttctatgag
acacctctccagttgctggagaaggtcaagaatgtctttaatgaaacaaagaatctcctt
gacaaggactggaatattttcagcaagaactgcaacaacagctttgctgaatgctccagc
caagatgtggtgaccaagcctgattgcaactgcctgtaccccaaagccatccctagcagt
gacccggcctctgtctcccctcatcagcccctcgccccctccatggcccctgtggctggc
ttgacctgggaggactctgagggaactgagggcagctccctcttgcctggtgagcagccc
ctgcacacagtggatccaggcagtgccaagcagcggccacccaggagcacctgccagagc
tttgagccgccagagaccccagttgtcaaggacagcaccatcggtggctcaccacagcct
cgcccctctgtcggggccttcaaccccgggatggaggatattcttgactctgcaatgggc
actaattgggtcccagaagaagcctctggagaggccagtgagattcccgtaccccaaggg
acagagctttccccctccaggccaggagggggcagcatgcagacagagcccgccagaccc
agcaacttcctctcagcatcttctccactccctgcatcagcaaagggccaacagccggca
gatgtaactggtaccgccttgcccagggtgggccccgtgaggcccactggccaggactgg
aatcacaccccccagaagacagaccatccatctgccctgctcagagaccccccggagcca
ggctctcccaggatctcatcactgcgcccccagggcctcagcaacccctccaccctctct
gctcagccacagctttccagaagccactcctcgggcagcgtgctgccccttggggagctg
gagggcaggaggagcaccagggatcggaggagccccgcagagccagaaggaggaccagca
agtgaaggggcagccaggcccctgccccgttttaactccgttcctttgactgacacaggc
catgagaggcagtccgagggatccttcagcccgcagctccaggagtctgtcttccacctg
ctggtgcccagtgtcatcctggtcttgctggccgtcggaggcctcttgttctacaggtgg
aggcggcggagccatcaagagcctcagagagcggattctcccttggagcaaccagagggc
agccccctgactcaggatgacagacaggtggaactgccagtgtag
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