Homo sapiens (human): 147111
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Entry
147111 CDS
T01001
Symbol
NOTUM, hNOTUM
Name
(RefSeq) notum, palmitoleoyl-protein carboxylesterase
KO
K19882
O-palmitoleoyl-L-serine hydrolase [EC:
3.1.1.98
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04310
Wnt signaling pathway
Network
nt06505
WNT signaling
Element
N01442
Wnt signaling modulation, Wnt inhibitor
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
147111 (NOTUM)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.98 [Wnt protein] O-palmitoleoyl-L-serine hydrolase
147111 (NOTUM)
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GFIT
Motif
Pfam:
PAE
Motif
Other DBs
NCBI-GeneID:
147111
NCBI-ProteinID:
NP_848588
OMIM:
609847
HGNC:
27106
Ensembl:
ENSG00000185269
UniProt:
Q6P988
Structure
PDB
PDBj
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All DBs
Position
17:complement(81952507..81961187)
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AA seq
496 aa
AA seq
DB search
MGRGVRVLLLLSLLHCAGGSEGRKTWRRRGQQPPPPPRTEAAPAAGQPVESFPLDFTAVE
GNMDSFMAQVKSLAQSLYPCSAQQLNEDLRLHLLLNTSVTCNDGSPAGYYLKESRGSRRW
LLFLEGGWYCFNRENCDSRYDTMRRLMSSRDWPRTRTGTGILSSQPEENPYWWNANMVFI
PYCSSDVWSGASSKSEKNEYAFMGALIIQEVVRELLGRGLSGAKVLLLAGSSAGGTGVLL
NVDRVAEQLEKLGYPAIQVRGLADSGWFLDNKQYRHTDCVDTITCAPTEAIRRGIRYWNG
VVPERCRRQFQEGEEWNCFFGYKVYPTLRCPVFVVQWLFDEAQLTVDNVHLTGQPVQEGL
RLYIQNLGRELRHTLKDVPASFAPACLSHEIIIRSHWTDVQVKGTSLPRALHCWDRSLHD
SHKASKTPLKGCPVHLVDSCPWPHCNPSCPTVRDQFTGQEMNVAQFLMHMGFDMQTVAQP
QGLEPSELLGMLSNGS
NT seq
1491 nt
NT seq
+upstream
nt +downstream
nt
atgggccgaggggtgcgcgtgctgctgctgctgagcctgctgcactgcgccgggggcagc
gagggcaggaagacctggcggcgccggggtcagcagccgcctcctcccccgcggaccgag
gcggcgccggcggccggacagcccgtggagagcttcccgctggacttcacggccgtggag
ggtaacatggacagcttcatggcgcaagtcaagagcctggcgcagtccctgtacccctgc
tccgcgcagcagctcaacgaggacctgcgcctgcacctcctactcaacacctcggtgacc
tgcaacgacggcagccccgccggctactacctgaaggagtccaggggcagccggcggtgg
ctcctcttcctggaaggcggctggtactgcttcaaccgcgagaactgcgactccagatac
gacaccatgcggcgcctcatgagctcccgggactggccgcgcactcgcacaggcacaggg
atcctgtcctcacagccggaggagaacccctactggtggaacgcaaacatggtcttcatc
ccctactgctccagtgatgtttggagcggggcttcatccaagtctgagaagaacgagtac
gccttcatgggcgccctcatcatccaggaggtggtgcgggagcttctgggcagagggctg
agcggggccaaggtgctgctgctggccgggagcagcgcggggggcaccggggtgctcctg
aatgtggaccgtgtggctgagcagctggagaagctgggctacccagccatccaggtgcga
ggcctggctgactccggctggttcctggacaacaagcagtatcgccacacagactgcgtc
gacacgatcacgtgcgcgcccacggaggccatccgccgtggcatcaggtactggaacggg
gtggtcccggagcgctgccgacgccagttccaggagggcgaggagtggaactgcttcttt
ggctacaaggtctacccgaccctgcgctgccctgtgttcgtggtgcagtggctgtttgac
gaggcacagctgacggtggacaacgtgcacctgacggggcagccggtgcaggagggcctg
cggctgtacatccagaacctcggccgcgagctgcgccacacactcaaggacgtgccggcc
agctttgcccccgcctgcctctcccatgagatcatcatccggagccactggacggatgtc
caggtgaaggggacgtcgctgccccgagcactgcactgctgggacaggagcctccatgac
agccacaaggccagcaagacccccctcaagggctgccccgtccacctggtggacagctgc
ccctggccccactgcaacccctcatgccccaccgtccgagaccagttcacggggcaagag
atgaacgtggcccagttcctcatgcacatgggcttcgacatgcagacggtggcccagccg
cagggactggagcccagtgagctgctggggatgctgagcaacggaagctag
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