NETWORK: N01442
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Entry
N01442 Network
Name
Wnt signaling modulation, Wnt inhibitor
Definition
(SFRP,
WIF1,
CER1,
NOTUM,
TRABD2) -| WNT
Expanded
((6422,
6423,
2487,
6424,
6425),
11197,
9350,
147111,
(129293,
388630)) -| (7471,
7472,
7482,
7473,
89780,
54361,
7474,
81029,
7475,
7476,
7477,
7478,
7479,
7483,
7484,
80326,
7480,
51384)
Class
nt06505
WNT signaling
Type
Reference
Pathway
hsa04310
Wnt signaling pathway
Gene
6422
SFRP1; secreted frizzled related protein 1
6423
SFRP2; secreted frizzled related protein 2
2487
FRZB; frizzled related protein
6424
SFRP4; secreted frizzled related protein 4
6425
SFRP5; secreted frizzled related protein 5
11197
WIF1; WNT inhibitory factor 1
9350
CER1; cerberus 1, DAN family BMP antagonist
147111
NOTUM; notum, palmitoleoyl-protein carboxylesterase
129293
TRABD2A; TraB domain containing 2A
388630
TRABD2B; TraB domain containing 2B
7471
WNT1; Wnt family member 1
7472
WNT2; Wnt family member 2
7482
WNT2B; Wnt family member 2B
7473
WNT3; Wnt family member 3
89780
WNT3A; Wnt family member 3A
54361
WNT4; Wnt family member 4
7474
WNT5A; Wnt family member 5A
81029
WNT5B; Wnt family member 5B
7475
WNT6; Wnt family member 6
7476
WNT7A; Wnt family member 7A
7477
WNT7B; Wnt family member 7B
7478
WNT8A; Wnt family member 8A
7479
WNT8B; Wnt family member 8B
7483
WNT9A; Wnt family member 9A
7484
WNT9B; Wnt family member 9B
80326
WNT10A; Wnt family member 10A
7480
WNT10B; Wnt family member 10B
51384
WNT16; Wnt family member 16
Reference
PMID:
34456337
Authors
Yu F, Yu C, Li F, Zuo Y, Wang Y, Yao L, Wu C, Wang C, Ye L
Title
Wnt/beta-catenin signaling in cancers and targeted therapies.
Journal
Signal Transduct Target Ther 6:307 (2021)
DOI:
10.1038/s41392-021-00701-5
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