Homo sapiens (human): 1520 Help Entry 1520              CDS       T01001                                  Symbol CTSS Name (RefSeq) cathepsin S   KO K01368   cathepsin S [EC:3.4.22.27] Organism hsa  Homo sapiens (human) Pathway hsa04142   Lysosome hsa04145   Phagosome hsa04210   Apoptosis hsa04612   Antigen processing and presentation hsa05152   Tuberculosis Drug target Petesicatib:  D11376 Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     1520 (CTSS)    04142 Lysosome     1520 (CTSS)   09143 Cell growth and death    04210 Apoptosis     1520 (CTSS)  09150 Organismal Systems   09151 Immune system    04612 Antigen processing and presentation     1520 (CTSS)  09160 Human Diseases   09171 Infectious disease: bacterial    05152 Tuberculosis     1520 (CTSS)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:hsa01002]     1520 (CTSS)   09182 Protein families: genetic information processing    03110 Chaperones and folding catalysts [BR:hsa03110]     1520 (CTSS) Enzymes [BR:hsa01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.27  cathepsin S      1520 (CTSS) Peptidases and inhibitors [BR:hsa01002]  Cysteine peptidases   Family C1: papain family    1520 (CTSS) Chaperones and folding catalysts [BR:hsa03110]  Intramolecular chaperones   Papain family    1520 (CTSS) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C1 Inhibitor_I29 Peptidase_C1_2 Motif Other DBs NCBI-GeneID:  1520 NCBI-ProteinID:  NP_004070 OMIM:  116845 HGNC:  2545 Ensembl:  ENSG00000163131 UniProt:  P25774 Structure PDBPDBj LinkDB All DBs Position 1:complement(150730188..150765778) Genome browser AA seq 331 aa AA seqDB search MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVD WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGC NGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKE AVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSW GHNFGEEGYIRMARNKGNHCGIASFPSYPEI NT seq 996 nt NT seq  +upstreamnt  +downstreamnt atgaaacggctggtttgtgtgctcttggtgtgctcctctgcagtggcacagttgcataaa gatcctaccctggatcaccactggcatctctggaagaaaacctatggcaaacaatacaag gaaaagaatgaagaagcagtacgacgtctcatctgggaaaagaatctaaagtttgtgatg cttcacaacctggagcattcaatgggaatgcactcatacgatctgggcatgaaccacctg ggagacatgaccagtgaagaagtgatgtctttgatgagttccctgagagttcccagccag tggcagagaaatatcacatataagtcaaaccctaatcggatattgcctgattctgtggac tggagagagaaagggtgtgttactgaagtgaaatatcaaggttcttgtggtgcttgctgg gctttcagtgctgtgggggccctggaagcacagctgaagctgaaaacaggaaagctggtg tctctcagtgcccagaacctggtggattgctcaactgaaaaatatggaaacaaaggctgc aatggtggcttcatgacaacggctttccagtacatcattgataacaagggcatcgactca gacgcttcctatccctacaaagccatggatcagaaatgtcaatatgactcaaaatatcgt gctgccacatgttcaaagtacactgaacttccttatggcagagaagatgtcctgaaagaa gctgtggccaataaaggcccagtgtctgttggtgtagatgcgcgtcatccttctttcttc ctctacagaagtggtgtctactatgaaccatcctgtactcagaatgtgaatcatggtgta cttgtggttggctatggtgatcttaatgggaaagaatactggcttgtgaaaaacagctgg ggccacaactttggtgaagaaggatatattcggatggcaagaaataaaggaaatcattgt gggattgctagctttccctcttacccagaaatctag

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