Homo sapiens (human): 161725
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Entry
161725 CDS
T01001
Symbol
OTUD7A, C15orf16, C16ORF15, CEZANNE2, NEDHS, OTUD7
Name
(RefSeq) OTU deubiquitinase 7A
KO
K11860
OTU domain-containing protein 7 [EC:
3.4.19.12
]
Organism
hsa
Homo sapiens (human)
Disease
H02715
Neurodevelopmental disorder with defects of ubiquitin-proteasome system
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
161725 (OTUD7A)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
hsa04121
]
161725 (OTUD7A)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.19 Omega peptidases
3.4.19.12 ubiquitinyl hydrolase 1
161725 (OTUD7A)
Peptidases and inhibitors [BR:
hsa01002
]
Cysteine peptidases
Family C64
161725 (OTUD7A)
Ubiquitin system [BR:
hsa04121
]
Deubiquitinating enzyme (DUB)
Ubiquitin-specific proteases (UBPs)
OTU
161725 (OTUD7A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
OTU
UBA_8
zf-A20
UBA_4
TAP_C
MIB_HERC2
DUF6303
Motif
Other DBs
NCBI-GeneID:
161725
NCBI-ProteinID:
NP_570971
OMIM:
612024
HGNC:
20718
Ensembl:
ENSG00000169918
UniProt:
Q8TE49
Structure
PDB
PDBj
LinkDB
All DBs
Position
15:complement(31475398..31870673)
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AA seq
926 aa
AA seq
DB search
MVSSVLPNPTSAECWAALLHDPMTLDMDAVLSDFVRSTGAEPGLARDLLEGKNWDLTAAL
SDYEQLRQVHTANLPHVFNEGRGPKQPEREPQPGHKVERPCLQRQDDIAQEKRLSRGISH
ASSAIVSLARSHVASECNNEQFPLEMPIYTFQLPDLSVYSEDFRSFIERDLIEQATMVAL
EQAGRLNWWSTVCTSCKRLLPLATTGDGNCLLHAASLGMWGFHDRDLVLRKALYTMMRTG
AEREALKRRWRWQQTQQNKEEEWEREWTELLKLASSEPRTHFSKNGGTGGGVDNSEDPVY
ESLEEFHVFVLAHILRRPIVVVADTMLRDSGGEAFAPIPFGGIYLPLEVPPNRCHCSPLV
LAYDQAHFSALVSMEQRDQQREQAVIPLTDSEHKLLPLHFAVDPGKDWEWGKDDNDNARL
AHLILSLEAKLNLLHSYMNVTWIRIPSETRAPLAQPESPTASAGEDVQSLADSLDSDRDS
VCSNSNSNNGKNGKDKEKEKQRKEKDKTRADSVANKLGSFSKTLGIKLKKNMGGLGGLVH
GKMGRANSANGKNGDSAERGKEKKAKSRKGSKEESGASASTSPSEKTTPSPTDKAAGASP
AEKGGGPRGDAWKYSTDVKLSLNILRAAMQGERKFIFAGLLLTSHRHQFHEEMIGYYLTS
AQERFSAEQEQRRRDAATAAAAAAAAAAATAKRPPRRPETEGVPVPERASPGPPTQLVLK
LKERPSPGPAAGRAARAAAGGTASPGGGARRASASGPVPGRSPPAPARQSVIHVQASGAR
DEACAPAVGALRPCATYPQQNRSLSSQSYSPARAAALRTVNTVESLARAVPGALPGAAGT
AGAAEHKSQTYTNGFGALRDGLEFADADAPTARSNGECGRGGPGPVQRRCQRENCAFYGR
AETEHYCSYCYREELRRRREARGARP
NT seq
2781 nt
NT seq
+upstream
nt +downstream
nt
atggtttctagtgtgcttccaaaccccacctcggctgagtgttgggcagcacttctacat
gatcctatgactcttgatatggacgcagtcctgtcagactttgttcggtccacgggggca
gaacctggtctggccagagacctgctggaaggcaaaaactgggacctgacagccgctctg
agcgactatgagcagctccgccaggtgcacacagccaatctgccacatgtgttcaatgaa
gggcggggtcccaagcagccagagcgagagccacagcccgggcacaaggtggagcgaccc
tgcctgcagaggcaggacgacattgcccaagaaaagcggctttcccgggggatttcccac
gccagctcagccatcgtctccctggcccggtcccacgtggcaagtgaatgcaacaacgag
cagttccccctggagatgccaatctacacattccagttgccagacctgagcgtgtacagc
gaggatttcaggagcttcatcgagcgggacttgatcgagcaggcaacaatggtggctttg
gagcaggcaggtcgcctgaactggtggtccactgtgtgcacgagctgtaaacggcttctt
cctctggccacaacaggggatgggaactgccttttacatgctgcttcactgggaatgtgg
gggtttcacgaccgggacctggtgttacggaaagctctctataccatgatgaggacggga
gctgagagggaagccctgaagcggaggtggaggtggcagcagacgcagcagaataaggag
gaggagtgggagcgggagtggacggagctgctgaagctggcctccagcgagccgcgcaca
cacttcagcaagaatggcggcacgggcgggggtgtggacaactctgaggaccccgtgtac
gagagcctggaagagttccacgtttttgtcctagcccatatattaagaaggcccatcgtt
gttgtggcagatacaatgttaagagactcaggtggagaagcgttcgcacccatcccattc
ggagggatctacctgcccttggaggtccctcccaacagatgccactgctcgcctctggtt
ctggcctatgatcaagcccatttctctgcccttgtgtccatggaacagagagaccagcaa
agagaacaagccgtgatccccctgacggattctgagcacaagctgctgcctctgcacttt
gcagtggaccctggcaaggactgggagtgggggaaagacgacaacgataacgcccggctg
gcccaccttatcctgtcgctagaagccaagctgaaccttctgcacagctacatgaacgtg
acgtggatccggatcccctccgagacacgggcgcccctggcacagccggagtctcccacg
gcctcggcaggggaggacgtgcagtccctggccgactcgctggactcggaccgcgattcg
gtgtgcagcaattctaacagcaataacggcaagaacggcaaggacaaggagaaggagaag
cagcgcaaggagaaggacaagacgcgcgccgactccgtggccaacaagctgggcagcttc
agcaagacgctgggcatcaagctgaagaaaaacatgggcggcctcggcggcctggtgcac
ggcaagatgggccgcgccaactccgccaatggcaagaacggggactcggccgagcggggc
aaggagaagaaggccaagtcgcgcaagggcagcaaggaggagtctggtgcgtcggccagc
acgtcgccgtcggaaaagaccacgccgtcgcccacagacaaggcagcgggcgcgtcgccg
gcggagaagggcggtgggccgcggggcgacgcctggaagtacagcacggatgtgaagctg
agcctcaacatcctgcgcgccgccatgcagggggagcgcaagttcatcttcgccggcctg
ctgctcaccagccaccggcaccagttccacgaggagatgatcggctactacctgacgagc
gcgcaggagcgcttcagcgccgagcaggagcagcggcgccgcgacgccgctactgcggcc
gccgctgccgccgccgccgccgccgccacggccaagcggccgccgcgcagaccggagacg
gagggcgtgccggtcccggagcgcgcctctccgggcccacccacgcagctggtgctcaag
ctcaaggagcggccgagccccgggcccgcggcagggcgtgcggcgcgggcggcggcgggc
ggcacggcctccccggggggaggcgcgcggcgtgcgagcgccagcggaccagtgcctggc
cgcagccccccggcgccagcgcgccagagcgtcatccacgtgcaggcgtcgggcgcgcgg
gacgaggcgtgcgcgccggccgtgggggcgctgcggccgtgcgccacgtacccgcagcag
aaccgctcgctgtcgtcgcagagctacagcccggcgcgcgccgccgccctgcgcaccgtc
aacacggtcgagtcgctggcgcgcgcggtgcccggggccctaccgggcgcggcggggacg
gcgggggcggccgagcacaagtcgcagacctacaccaacggcttcggcgccctgcgcgac
ggcctggagttcgccgacgccgacgcgccgaccgcgcgctcgaacggtgagtgcggccgt
ggcggcccggggccggtgcagcggcgctgccagcgcgagaactgtgcgttctacgggcgc
gccgagaccgagcactactgctcctactgctaccgcgaggagctgcggcggcggcgcgag
gcgcgcggggcccggccctga
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