Homo sapiens (human): 1630
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Entry
1630 CDS
T01001
Gene name
DCC, CRC18, CRCR1, HGPPS2, IGDCC1, MRMV1, NTN1R1
Definition
(RefSeq) DCC netrin 1 receptor
KO
K06765
deleted in colorectal carcinoma
Organism
hsa
Homo sapiens (human)
Pathway
hsa04360
Axon guidance
hsa05200
Pathways in cancer
hsa05210
Colorectal cancer
Network
nt06231
Apoptosis
nt06260
Colorectal cancer
Element
N00101
DCC-apoptotic pathway
N00102
Loss of DCC to DCC-apoptotic pathway
Disease
H00020
Colorectal cancer
H00044
Cancer of the anal canal
H01287
Congenital mirror movements
H02450
Horizontal gaze palsy with progressive scoliosis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09158 Development and regeneration
04360 Axon guidance
1630 (DCC)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
1630 (DCC)
09162 Cancer: specific types
05210 Colorectal cancer
1630 (DCC)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Neogenin_C
fn3
I-set
Ig_3
ig
Ig_2
V-set
Pur_ac_phosph_N
C2-set_2
Interfer-bind
Ig_4
Ig_6
Herpes_gE
Protocadherin
EphA2_TM
FAM176
V-set_CD47
CD34_antigen
Ly49
TMEM154
Motif
Other DBs
NCBI-GeneID:
1630
NCBI-ProteinID:
NP_005206
OMIM:
120470
HGNC:
2701
Ensembl:
ENSG00000187323
Vega:
OTTHUMG00000132698
Pharos:
P43146
(Tbio)
UniProt:
P43146
Q49AK4
LinkDB
All DBs
Structure
PDB:
3AU4
5X83
4URT
2ED7
2ED8
2ED9
2EDB
2EDD
2EDE
Thumbnails
Position
18q21.2
AA seq
1447 aa
AA seq
DB search
MENSLRCVWVPKLAFVLFGASLFSAHLQVTGFQIKAFTALRFLSEPSDAVTMRGGNVLLD
CSAESDRGVPVIKWKKDGIHLALGMDERKQQLSNGSLLIQNILHSRHHKPDEGLYQCEAS
LGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDL
TPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGLHRQL
YFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNV
TDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVP
TVNWMKNGDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKP
AIPSSSVLPSAPRDVVPVLVSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDNRERALNTT
QPGSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVPGPVENLQAVSTS
PTSILITWEPPAYANGPVQGYRLFCTEVSTGKEQNIEVDGLSYKLEGLKKFTEYSLRFLA
YNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKI
RHRKTTRRGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPENDL
DESQVPDQPSSLHVRPQTNCIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRY
YSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSVPDL
STPMLPPVGVQAVALTHDAVRVSWADNSVPKNQKTSEVRLYTVRWRTSFSASAKYKSEDT
TSLSYTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREGKP
RAVIVSWQPPLEANGKITAYILFYTLDKNIPIDDWIMETISGDRLTHQIMDLNLDTMYYF
RIQARNSKGVGPLSDPILFRTLKVEHPDKMANDQGRHGDGGYWPVDTNLIDRSTLNEPPI
GQMHPPHGSVTPQKNSNLLVIIVVTVGVITVLVVVIVAVICTRRSSAQQRKKRATHSAGK
RKGSQKDLRPPDLWIHHEEMEMKNIEKPSGTDPAGRDSPIQSCQDLTPVSHSQSETQLGS
KSTSHSGQDTEEAGSSMSTLERSLAARRAPRAKLMIPMDAQSNNPAVVSAIPVPTLESAQ
YPGILPSPTCGYPHPQFTLRPVPFPTLSVDRGFGAGRSQSVSEGPTTQQPPMLPPSQPEH
SSSEEAPSRTIPTACVRPTHPLRSFANPLLPPPMSAIEPKVPYTPLLSQPGPTLPKTHVK
TASLGLAGKARSPLLPVSVPTAPEVSEESHKPTEDSANVYEQDDLSEQMASLEGLMKQLN
AITGSAF
NT seq
4344 nt
NT seq
+upstream
nt +downstream
nt
atggagaatagtcttagatgtgtttgggtacccaagctggcttttgtactcttcggagct
tccttgttcagcgcgcatcttcaagtaaccggttttcaaattaaagctttcacagcactg
cgcttcctctcagaaccttctgatgccgtcacaatgcggggaggaaatgtcctcctcgac
tgctccgcggagtccgaccgaggagttccagtgatcaagtggaagaaagatggcattcat
ctggccttgggaatggatgaaaggaagcagcaactttcaaatgggtctctgctgatacaa
aacatacttcattccagacaccacaagccagatgagggactttaccaatgtgaggcatct
ttaggagattctggctcaattattagtcggacagcaaaagttgcagtagcaggaccactg
aggttcctttcacagacagaatctgtcacagccttcatgggagacacagtgctactcaag
tgtgaagtcattggggagcccatgccaacaatccactggcagaagaaccaacaagacctg
actccaatcccaggtgactcccgagtggtggtcttgccctctggagcattgcagatcagc
cgactccaaccgggggacattggaatttaccgatgctcagctcgaaatccagccagctca
agaacaggaaatgaagcagaagtcagaattttatcagatccaggactgcatagacagctg
tattttctgcaaagaccatccaatgtagtagccattgaaggaaaagatgctgtcctggaa
tgttgtgtttctggctatcctccaccaagttttacctggttacgaggcgaggaagtcatc
caactcaggtctaaaaagtattctttattgggtggaagcaacttgcttatctccaatgtg
acagatgatgacagtggaatgtatacctgtgttgtcacatataaaaatgagaatattagt
gcctctgcagagctcacagtcttggttccgccatggtttttaaatcatccttccaacctg
tatgcctatgaaagcatggatattgagtttgaatgtacagtctctggaaagcctgtgccc
actgtgaattggatgaagaatggagatgtggtcattcctagtgattattttcagatagtg
ggaggaagcaacttacggatacttggggtggtgaagtcagatgaaggcttttatcaatgt
gtggctgaaaatgaggctggaaatgcccagaccagtgcacagctcattgtccctaagcct
gctatcccaagctccagtgtcctcccttcggctcccagagatgtggtccctgtcttggtt
tccagccgatttgtccgtctcagctggcgcccacctgcagaagcgaaagggaacattcaa
actttcacggtctttttctccagagaaggtgacaacagggaacgagcattgaatacaaca
cagcctgggtcccttcagctcactgtgggaaacctgaagccagaagccatgtacaccttt
cgagttgtggcttacaatgaatggggaccgggagagagttctcaacccatcaaggtggcc
acacagcctgagttgcaagttccagggccagtagaaaacctgcaagctgtatctacctca
cctacctcaattcttattacctgggaaccccctgcctatgcaaacggtccagtccaaggt
tacagattgttctgcactgaggtgtccacaggaaaagaacagaatatagaggttgatgga
ctatcttataaactggaaggcctgaaaaaattcaccgaatatagtcttcgattcttagct
tataatcgctatggtccgggcgtctctactgatgatataacagtggttacactttctgac
gtgccaagtgccccgcctcagaacgtctccctggaagtggtcaattcaagaagtatcaaa
gttagctggctgcctcctccatcaggaacacaaaatggatttattaccggctataaaatt
cgacacagaaagacgacccgcaggggtgagatggaaacactggagccaaacaacctctgg
tacctattcacaggactggagaaaggaagtcagtacagtttccaggtgtcagccatgaca
gtcaatggtactggaccaccttccaactggtatactgcagagactccagagaatgatcta
gatgaatctcaagttcctgatcaaccaagctctcttcatgtgaggccccagactaactgc
atcatcatgagttggactcctcccttgaacccaaacatcgtggtgcgaggttatattatc
ggttatggcgttgggagcccttacgctgagacagtgcgtgtggacagcaagcagcgatat
tattccattgagaggttagagtcaagttcccattatgtaatctccctaaaagcttttaac
aatgccggagaaggagttcctctttatgaaagtgccaccaccaggtctataaccgatccc
actgacccagttgattattatcctttgcttgatgatttccccacctcggtcccagatctc
tccacccccatgctcccaccagtaggtgtacaggctgtggctcttacccatgatgctgtg
agggtcagctgggcagacaactctgtccctaagaaccaaaagacgtctgaggtgcgactt
tacaccgtccggtggagaaccagcttttctgcaagtgcaaaatacaagtcagaagacaca
acatctctaagttacacagcaacaggcctcaaaccaaacacaatgtatgaattctcggtc
atggtaacaaaaaacagaaggtccagtacttggagcatgactgcacatgccaccacgtat
gaagcagcccccacctctgctcccaaggacttgacagtcattactagggaagggaagcct
cgtgccgtcattgtgagttggcagcctcccttggaagccaatgggaaaattactgcttac
atcttattttataccttggacaagaacatcccaattgatgactggattatggaaacaatc
agtggtgataggcttactcatcaaatcatggatctcaaccttgatactatgtattacttt
cgaattcaagcacgaaattcaaaaggagtggggccactctctgatcctatcctcttcagg
actctgaaagtggaacaccctgacaaaatggctaatgaccaaggtcgtcatggagatgga
ggttattggccagttgatactaatttgattgatagaagcaccctaaatgagccgccaatt
ggacaaatgcaccccccgcatggcagtgtcactcctcagaagaacagcaacctgcttgtg
atcattgtggtcaccgttggtgtcatcacagtgctggtagtggtcatcgtggctgtgatt
tgcacccgacgctcttcagcccagcagagaaagaaacgggccacccacagtgctggcaaa
aggaagggcagccagaaggacctccgaccccctgatctttggatccatcatgaagaaatg
gagatgaaaaatattgaaaagccatctggcactgaccctgcaggaagggactctcccatc
caaagttgccaagacctcacaccagtcagccacagccagtcagaaacccaactgggaagc
aaaagcacctctcattcaggtcaagacactgaggaagcagggagctctatgtccactctg
gagaggtcgctggctgcacgccgagccccccgggccaagctcatgattcccatggatgcc
cagtccaacaatcctgctgtcgtgagcgccatcccggtgccaacgctagaaagtgcccag
tacccaggaatcctcccgtctcccacctgtggatatccccacccgcagttcactctccgg
cctgtgccattcccaacactctcagtggaccgaggtttcggagcaggaagaagtcagtca
gtgagtgaaggaccaactacccaacaaccacctatgctgcccccatctcagcctgagcat
tctagcagcgaggaggcaccaagcagaaccatccccacagcttgtgttcgaccaactcac
ccactccgcagctttgctaatcctttgctacctccaccaatgagtgcaatagaaccgaaa
gtcccttacacaccacttttgtctcagccagggcccactcttcctaagacccatgtgaaa
acagcctcccttgggttggctggaaaagcaagatcccctttgcttcctgtgtctgtgcca
acagcccctgaagtgtctgaggagagccacaaaccaacagaggattcagccaatgtgtat
gaacaggatgatctgagtgaacaaatggcaagtttggaaggactcatgaagcagcttaat
gccatcacaggctcagccttttaa
DBGET
integrated database retrieval system
