Homo sapiens (human): 1654
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Entry
1654 CDS
T01001
Symbol
DDX3X, CAP-Rf, DBX, DDX14, DDX3, HLP2, MRX102, MRXSSB
Name
(RefSeq) DEAD-box helicase 3 X-linked
KO
K11594
ATP-dependent RNA helicase DDX3X [EC:
5.6.2.7
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04622
RIG-I-like receptor signaling pathway
hsa05161
Hepatitis B
hsa05203
Viral carcinogenesis
Network
nt06162
Hepatitis B virus (HBV)
nt06263
Hepatocellular carcinoma
nt06517
TLR signaling
Element
N00552
HBV pol to TLR3-IRF3 signaling pathway
Disease
H00658
X-linked syndromic intellectual developmental disorder
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09151 Immune system
04622 RIG-I-like receptor signaling pathway
1654 (DDX3X)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
1654 (DDX3X)
09172 Infectious disease: viral
05161 Hepatitis B
1654 (DDX3X)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
hsa03019
]
1654 (DDX3X)
03041 Spliceosome [BR:
hsa03041
]
1654 (DDX3X)
03036 Chromosome and associated proteins [BR:
hsa03036
]
1654 (DDX3X)
Enzymes [BR:
hsa01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.7 DEAD-box RNA helicase
1654 (DDX3X)
Messenger RNA biogenesis [BR:
hsa03019
]
Eukaryotic type
mRNA surveillance and transport factors
Transport factors
eIF4F and regulatory proteins
1654 (DDX3X)
mRNA cycle factors
Common to processing body (P body) and stress granule
1654 (DDX3X)
Spliceosome [BR:
hsa03041
]
Other splicing related proteins
Spliceosome associated proteins (SAPs)
RNA helicase-like proteins
1654 (DDX3X)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Gene silencing
RISC (RNA-induced silencing complex)
1654 (DDX3X)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DEAD
Helicase_C
ResIII
Utp25_C
Cas3-like_C_2
Motif
Other DBs
NCBI-GeneID:
1654
NCBI-ProteinID:
NP_001347
OMIM:
300160
HGNC:
2745
Ensembl:
ENSG00000215301
UniProt:
O00571
Structure
PDB
LinkDB
All DBs
Position
X:41333308..41364472
Genome browser
AA seq
662 aa
AA seq
DB search
MSHVAVENALGLDQQFAGLDLNSSDNQSGGSTASKGRYIPPHLRNREATKGFYDKDSSGW
SSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRSDYDGIGSRGDRSGFGKFE
RGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIE
SFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILS
QIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV
YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ
IRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVV
WVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR
EEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGL
ATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSSRFSGGFGAR
DYRQSSGASSSSFSSSRASSSRSGGGGHGSSRGFGGGGYGGFYNSDGYGGNYNSQGVDWW
GN
NT seq
1989 nt
NT seq
+upstream
nt +downstream
nt
atgagtcatgtggcagtggaaaatgcgctcgggctggaccagcagtttgctggcctagac
ctgaactcttcagataatcagagtggaggaagtacagccagcaaagggcgctatattcct
cctcatttaaggaaccgagaagctactaaaggtttctacgataaagacagttcagggtgg
agttctagcaaagataaggatgcgtatagcagttttggatctcgtagtgattcaagaggg
aagtctagcttcttcagtgatcgtggaagtggatcaaggggaaggtttgatgatcgtgga
cggagtgattacgatggcattggcagccgtggtgacagaagtggctttggcaaatttgaa
cgtggtggaaacagtcgctggtgtgacaaatcagatgaagatgattggtcaaaaccactc
ccaccaagtgaacgcttggaacaggaactcttttctggaggcaacactgggattaatttt
gagaaatacgatgacattccagttgaggcaacaggcaacaactgtcctccacatattgaa
agtttcagtgatgttgagatgggagaaattatcatgggaaacattgagcttactcgttat
actcgcccaactccagtgcaaaagcatgctattcctattatcaaagagaaaagagacttg
atggcttgtgcccaaacagggtctggaaaaactgcagcatttctgttgcccatcttgagt
cagatttattcagatggtccaggcgaggctttgagggccatgaaggaaaatggaaggtat
gggcgccgcaaacaatacccaatctccttggtattagcaccaacgagagagttggcagta
cagatctacgaggaagccagaaaattttcataccgatctagagttcgtccttgcgtggtt
tatggtggtgccgatattggtcagcagattcgagacttggaacgtggatgccatttgtta
gtagccactccaggacgtctagtggatatgatggaaagaggaaagattggattagacttt
tgcaaatacttggtgttagatgaagctgatcggatgttggatatggggtttgagcctcag
attcgtagaatagtcgaacaagatactatgcctccaaagggtgtccgccacactatgatg
tttagtgctacttttcctaaggaaatacagatgctggctcgtgatttcttagatgaatat
atcttcttggctgtaggaagagttggctctacctctgaaaacatcacacagaaagtagtt
tgggtggaagaatcagacaaacggtcatttctgcttgacctcctaaatgcaacaggcaag
gattcactgaccttagtgtttgtggagaccaaaaagggtgcagattctctggaggatttc
ttataccatgaaggatacgcatgtaccagcatccatggagaccgttctcagagggataga
gaagaggcccttcaccagttccgctcaggaaaaagcccaattttagtggctacagcagta
gcagcaagaggactggacatttcaaatgtgaaacatgttatcaattttgacttgccaagt
gatattgaagaatatgtacatcgtattggtcgtacgggacgtgtaggaaaccttggcctg
gcaacctcattctttaacgagaggaacataaatattactaaggatttgttggatcttctt
gttgaagctaaacaagaagtgccgtcttggttagaaaacatggcttatgaacaccactac
aagggtagcagtcgtggacgttctaagagtagcagatttagtggagggtttggtgccaga
gactaccgacaaagtagcggtgccagcagttccagcttcagcagcagccgcgcaagcagc
agccgcagtggcggaggtggccacggtagcagcagaggatttggtggaggtggctatgga
ggcttttacaacagtgatggatatggaggaaattataactcccagggggttgactggtgg
ggtaactga
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