Homo sapiens (human): 1843 Help Entry 1843              CDS       T01001                                  Symbol DUSP1, CL100, HVH1, MKP-1, MKP1, PTPN10 Name (RefSeq) dual specificity phosphatase 1   KO K21278   dual specificity protein phosphatase 1 [EC:3.1.3.16 3.1.3.48] Organism hsa  Homo sapiens (human) Pathway hsa04010   MAPK signaling pathway hsa04726   Serotonergic synapse hsa05012   Parkinson disease hsa05418   Fluid shear stress and atherosclerosis Network nt06463  Parkinson disease nt06526  MAPK signaling   Element N01058   Mutation-inactivated DJ1 to to p53-mediated transcription N01593   Regulation of GF-RTK-RAS-ERK signaling, PTP Brite KEGG Orthology (KO) [BR:hsa00001]  09150 Organismal Systems   09156 Nervous system    04726 Serotonergic synapse     1843 (DUSP1)  09160 Human Diseases   09164 Neurodegenerative disease    05012 Parkinson disease     1843 (DUSP1)   09166 Cardiovascular disease    05418 Fluid shear stress and atherosclerosis     1843 (DUSP1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:hsa01009]     1843 (DUSP1) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.3  Phosphoric-monoester hydrolases     3.1.3.16  protein-serine/threonine phosphatase      1843 (DUSP1)     3.1.3.48  protein-tyrosine-phosphatase      1843 (DUSP1) Protein phosphatases and associated proteins [BR:hsa01009]  Protein tyrosine phosphatases (PTPs)   Class I PTPs (Dual specificity phosphatases)    MAPK phosphatases     1843 (DUSP1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  DSPc Rhodanese Tc-R-P Y_phosphatase PTP-SAK Init_tRNA_PT PTP-NADK PTPlike_phytase Motif Other DBs NCBI-GeneID:  1843 NCBI-ProteinID:  NP_004408 OMIM:  600714 HGNC:  3064 Ensembl:  ENSG00000120129 UniProt:  P28562 B4DU40 Structure PDBPDBj LinkDB All DBs Position 5:complement(172768096..172771195) Genome browser AA seq 367 aa AA seqDB search MVMEVGTLDAGGLRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAM GLEHIVPNAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFF LKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPF LYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEA IDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFS FMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSP ITTSPSC NT seq 1104 nt NT seq  +upstreamnt  +downstreamnt atggtcatggaagtgggcaccctggacgctggaggcctgcgggcgctgctgggggagcga gcggcgcaatgcctgctgctggactgccgctccttcttcgctttcaacgccggccacatc gccggctctgtcaacgtgcgcttcagcaccatcgtgcggcgccgggccaagggcgccatg ggcctggagcacatcgtgcccaacgccgagctccgcggccgcctgctggccggcgcctac cacgccgtggtgttgctggacgagcgcagcgccgccctggacggcgccaagcgcgacggc accctggccctggcggccggcgcgctctgccgcgaggcgcgcgccgcgcaagtcttcttc ctcaaaggaggatacgaagcgttttcggcttcctgcccggagctgtgcagcaaacagtcg acccccatggggctcagccttcccctgagtactagcgtccctgacagcgcggaatctggg tgcagttcctgcagtaccccactctacgatcagggtggcccggtggaaatcctgcccttt ctgtacctgggcagtgcgtatcacgcttcccgcaaggacatgctggatgccttgggcatc actgccttgatcaacgtctcagccaattgtcccaaccattttgagggtcactaccagtac aagagcatccctgtggaggacaaccacaaggcagacatcagctcctggttcaacgaggcc attgacttcatagactccatcaagaatgctggaggaagggtgtttgtccactgccaggca ggcatttcccggtcagccaccatctgccttgcttaccttatgaggactaatcgagtcaag ctggacgaggcctttgagtttgtgaagcagaggcgaagcatcatctctcccaacttcagc ttcatgggccagctgctgcagtttgagtcccaggtgctggctccgcactgttcggcagag gctgggagccccgccatggctgtgctcgaccgaggcacctccaccaccaccgtgttcaac ttccccgtctccatccctgtccactccacgaacagtgcgctgagctaccttcagagcccc attacgacctctcccagctgctga

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