Homo sapiens (human): 1889
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Entry
1889 CDS
T01001
Symbol
ECE1, ECE
Name
(RefSeq) endothelin converting enzyme 1
KO
K01415
endothelin-converting enzyme [EC:
3.4.24.71
]
Organism
hsa
Homo sapiens (human)
Disease
H00910
Hirschsprung disease
H01633
High blood pressure
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
1889 (ECE1)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
1889 (ECE1)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.71 endothelin-converting enzyme 1
1889 (ECE1)
Peptidases and inhibitors [BR:
hsa01002
]
Metallo peptidases
Family M13: neprilysin family
1889 (ECE1)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
1889 (ECE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Peptidase_M13_N
Peptidase_M13
Motif
Other DBs
NCBI-GeneID:
1889
NCBI-ProteinID:
NP_001388
OMIM:
600423
HGNC:
3146
Ensembl:
ENSG00000117298
UniProt:
P42892
Structure
PDB
PDBj
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All DBs
Position
1:complement(21217250..21345504)
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AA seq
770 aa
AA seq
DB search
MRGVWPPPVSALLSALGMSTYKRATLDEEDLVDSLSEGDAYPNGLQVNFHSPRSGQRCWA
ARTQVEKRLVVLVVLLAAGLVACLAALGIQYQTRSPSVCLSEACVSVTSSILSSMDPTVD
PCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLENSTASVSEAERKAQV
YYRACMNETRIEELRAKPLMELIERLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVY
VSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEEAI
RPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYPVE
INESEPIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEV
MYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLS
TLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNF
SWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGG
IGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEPVN
GRHTLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTP
ESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW
NT seq
2313 nt
NT seq
+upstream
nt +downstream
nt
atgcggggcgtgtggccgcccccggtgtccgccctgctgtcggcgctggggatgtcgacg
tacaagcgggccacgctggacgaggaggacctggtggactcgctctccgagggcgacgca
taccccaacggcctgcaggtgaacttccacagcccccggagtggccagaggtgctgggct
gcacggacccaggtggagaagcggctggtggtgttggtggtacttctggcggcaggactg
gtggcctgcttggcagcactgggcatccagtaccagacaagatccccctctgtgtgcctg
agcgaagcttgtgtctcagtgaccagctccatcttgagctccatggaccccacagtggac
ccctgccatgacttcttcagctacgcctgtgggggctggatcaaggccaacccagtccct
gatggccactcacgctgggggaccttcagcaacctctgggaacacaaccaagcaatcatc
aagcacctcctcgaaaactccacggccagcgtgagcgaggcagagagaaaggcgcaagta
tactaccgtgcgtgcatgaacgagaccaggatcgaggagctcagggccaaacctctaatg
gagttgattgagaggctcgggggctggaacatcacaggtccctgggccaaggacaacttc
caggacaccctgcaggtggtcaccgcccactaccgcacctcacccttcttctctgtctat
gtcagtgccgattccaagaactccaacagcaacgtgatccaggtggaccagtctggcctg
ggcttgccctcgagagactattacctgaacaaaactgaaaacgagaaggtgctgaccgga
tatctgaactacatggtccagctggggaagctgctgggcggcggggacgaggaggccatc
cggccccagatgcagcagatcttggactttgagacggcactggccaacatcaccatccca
caggagaagcgccgtgatgaggagctcatctaccacaaagtgacggcagccgagctgcag
accttggcacccgccatcaactggttgccttttctcaacaccatcttctaccccgtggag
atcaatgaatccgagcctattgtggtctatgacaaggaataccttgagcagatctccact
ctcatcaacaccaccgacagatgcctgctcaacaactacatgatctggaacctggtgcgg
aaaacaagctccttccttgaccagcgctttcaggacgccgatgagaagttcatggaagtc
atgtacgggaccaagaagacctgtcttcctcgctggaagttttgcgtgagtgacacagaa
aacaacctgggctttgcgttgggccccatgtttgtcaaagcaaccttcgccgaggacagc
aagagcatagccaccgagatcatcctggagattaagaaggcatttgaggaaagcctgagc
accctgaagtggatggatgaggaaacccgaaaatcagccaaggaaaaggccgatgccatc
tacaacatgataggataccccaacttcatcatggatcccaaggagctggacaaagtgttt
aatgactacactgcagttccagacctctactttgaaaatgccatgcggtttttcaacttc
tcatggagggtcactgccgatcagctcaggaaagcccccaacagagatcagtggagcatg
accccgcccatggtgaacgcctactactcgcccaccaagaatgagattgtgtttccggcc
gggatcctgcaggcaccattctacacacgctcctcacccaaggccttaaactttggtggc
ataggtgtcgtcgtgggccatgagctgactcatgcttttgatgatcaaggacgggagtat
gacaaggacgggaacctccggccatggtggaagaactcatccgtggaggccttcaagcgt
cagaccgagtgcatggtagagcagtacagcaactacagcgtgaacggggagccggtgaac
gggcggcacaccctgggggagaacatcgccgacaacgggggtctcaaggcggcctatcgg
gcttaccagaactgggtgaagaagaacggggctgagcactcgctccccaccctgggcctc
accaataaccagctcttcttcctgggctttgcacaggtctggtgctccgtccgcacacct
gagagctcccacgaaggcctcatcaccgatccccacagcccctctcgcttccgggtcatc
ggctccctctccaattccaaggagttctcagaacacttccgctgcccacctggctcaccc
atgaacccgcctcacaagtgcgaagtctggtaa
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