Homo sapiens (human): 1901
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Entry
1901 CDS
T01001
Symbol
S1PR1, CD363, CHEDG1, D1S3362, ECGF1, EDG-1, EDG1, S1P1
Name
(RefSeq) sphingosine-1-phosphate receptor 1
KO
K04288
sphingosine 1-phosphate receptor 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04068
FoxO signaling pathway
hsa04071
Sphingolipid signaling pathway
hsa04080
Neuroactive ligand-receptor interaction
hsa04148
Efferocytosis
Network
nt06535
Efferocytosis
Element
N01750
Find-me signal (S1P)
Drug target
Amiselimod (
DG02399
):
D10904
D10905
Cenerimod:
D11283
Etrasimod (
DG02444
):
D10930
D10931
<US>
Fingolimod (
DG00741
):
D04187
<JP/US>
D10001
D12549
<US>
Mocravimod (
DG03288
):
D12771
D12772
Ozanimod (
DG02827
):
D10967
<US>
D10968
Ponesimod:
D11215
<US>
Siponimod (
DG03018
):
D11072
<JP/US>
D11460
Tamuzimod:
D12897
Udifitimod (
DG03227
):
D12376
D12377
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
1901 (S1PR1)
04071 Sphingolipid signaling pathway
1901 (S1PR1)
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
1901 (S1PR1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
1901 (S1PR1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04030 G protein-coupled receptors [BR:
hsa04030
]
1901 (S1PR1)
04090 CD molecules [BR:
hsa04090
]
1901 (S1PR1)
G protein-coupled receptors [BR:
hsa04030
]
Rhodopsin family
Lipid
Sphingolipid
1901 (S1PR1)
CD molecules [BR:
hsa04090
]
Proteins
1901 (S1PR1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
7tm_1
7TM_GPCR_Srsx
7tm_4
JTB
Motif
Other DBs
NCBI-GeneID:
1901
NCBI-ProteinID:
NP_001307659
OMIM:
601974
HGNC:
3165
Ensembl:
ENSG00000170989
Pharos:
P21453
(Tclin)
UniProt:
P21453
Structure
PDB
PDBj
LinkDB
All DBs
Position
1:101236899..101242313
Genome browser
AA seq
382 aa
AA seq
DB search
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFII
LENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLR
EGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIM
GWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKN
ISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLA
VLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSH
PQKDEGDNPETIMSSGNVNSSS
NT seq
1149 nt
NT seq
+upstream
nt +downstream
nt
atggggcccaccagcgtcccgctggtcaaggcccaccgcagctcggtctctgactacgtc
aactatgatatcatcgtccggcattacaactacacgggaaagctgaatatcagcgcggac
aaggagaacagcattaaactgacctcggtggtgttcattctcatctgctgctttatcatc
ctggagaacatctttgtcttgctgaccatttggaaaaccaagaaattccaccgacccatg
tactattttattggcaatctggccctctcagacctgttggcaggagtagcctacacagct
aacctgctcttgtctggggccaccacctacaagctcactcccgcccagtggtttctgcgg
gaagggagtatgtttgtggccctgtcagcctccgtgttcagtctcctcgccatcgccatt
gagcgctatatcacaatgctgaaaatgaaactccacaacgggagcaataacttccgcctc
ttcctgctaatcagcgcctgctgggtcatctccctcatcctgggtggcctgcctatcatg
ggctggaactgcatcagtgcgctgtccagctgctccaccgtgctgccgctctaccacaag
cactatatcctcttctgcaccacggtcttcactctgcttctgctctccatcgtcattctg
tactgcagaatctactccttggtcaggactcggagccgccgcctgacgttccgcaagaac
atttccaaggccagccgcagctctgagaagtcgctggcgctgctcaagaccgtaattatc
gtcctgagcgtcttcatcgcctgctgggcaccgctcttcatcctgctcctgctggatgtg
ggctgcaaggtgaagacctgtgacatcctcttcagagcggagtacttcctggtgttagct
gtgctcaactccggcaccaaccccatcatttacactctgaccaacaaggagatgcgtcgg
gccttcatccggatcatgtcctgctgcaagtgcccgagcggagactctgctggcaaattc
aagcgacccatcatcgccggcatggaattcagccgcagcaaatcggacaattcctcccac
ccccagaaagacgaaggggacaacccagagaccattatgtcttctggaaacgtcaactct
tcttcctag
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