 | | NETWORK: N01750 | |
| Entry |
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| Name |
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| Definition |
Caspase -> SPHK -> S1P -- S1PR1 -> NFAT => HIF1 => EPO |
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| Expanded |
(836,840,834) -> (8877,56848) -> C06124 -- 1901 -> (4772,4773,4775,4776) => 3091+405 => 2056 |
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| Class |
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| Type |
Reference
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| Pathway |
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| Gene |
| 8877 | SPHK1; sphingosine kinase 1 |
| 56848 | SPHK2; sphingosine kinase 2 |
| 1901 | S1PR1; sphingosine-1-phosphate receptor 1 |
| 4772 | NFATC1; nuclear factor of activated T cells 1 |
| 4773 | NFATC2; nuclear factor of activated T cells 2 |
| 4775 | NFATC3; nuclear factor of activated T cells 3 |
| 4776 | NFATC4; nuclear factor of activated T cells 4 |
| 3091 | HIF1A; hypoxia inducible factor 1 subunit alpha |
| 405 | ARNT; aryl hydrocarbon receptor nuclear translocator |
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| Metabolite |
| C06124 | Sphingosine 1-phosphate |
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| Reference |
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| Authors |
Li Y, Li Q, Fan GC |
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| Title |
Macrophage Efferocytosis in Cardiac Pathophysiology and Repair. |
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| Journal |
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| Reference |
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| Authors |
Luo B, Gan W, Liu Z, Shen Z, Wang J, Shi R, Liu Y, Liu Y, Jiang M, Zhang Z, Wu Y |
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| Title |
Erythropoeitin Signaling in Macrophages Promotes Dying Cell Clearance and Immune Tolerance. |
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| Journal |
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| Reference |
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| Authors |
Weigert A, Cremer S, Schmidt MV, von Knethen A, Angioni C, Geisslinger G, Brune B |
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| Title |
Cleavage of sphingosine kinase 2 by caspase-1 provokes its release from apoptotic cells. |
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| Journal |
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| LinkDB |
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