KEGG T01001: 1958

Homo sapiens (human): 1958

Entry

1958              CDS       T01001

Symbol

EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZIF268, ZNF225

Name

(RefSeq) early growth response 1

K09203

early growth response protein 1

Organism

hsa Homo sapiens (human)

Pathway

hsa04371

Apelin signaling pathway

hsa04912

GnRH signaling pathway

hsa04928

Parathyroid hormone synthesis, secretion and action

hsa04933

AGE-RAGE signaling pathway in diabetic complications

hsa05020

Prion disease

hsa05166

Human T-cell leukemia virus 1 infection

Network

nt06160 Human T-cell leukemia virus 1 (HTLV-1)
nt06465 Prion disease

Element

N00509

HTLV-1 Tax to SRF-mediated transcription

N01204

PRNP-PI3K-NOX2 signaling pathway

Drug target

Brivoligide:

D11341

Brivoligide sodium:

D11286

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    1958 (EGR1)
09150 Organismal Systems
  09152 Endocrine system
   04912 GnRH signaling pathway
    1958 (EGR1)
   04928 Parathyroid hormone synthesis, secretion and action
    1958 (EGR1)
09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    1958 (EGR1)
  09164 Neurodegenerative disease
   05020 Prion disease
    1958 (EGR1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    1958 (EGR1)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    1958 (EGR1)
Transcription factors [BR:hsa03000]
Eukaryotic type
  Zinc finger
   Cys2His2 SP/KLF family and related proteins
    1958 (EGR1)

SSDB

Motif

Pfam:

DUF3432 DUF3446 zf-H2C2_2 zf-C2H2 zf-C2H2_4 zf-C2H2_15 zf-C2HC_2 Cornifin C2CH-3rd_BIRD-IDD zf-BED zf-C2H2_ZNF462_1st Zf-C2H2_ZNF451_1st zf-H2C2_5

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Structure

LinkDB

Position

5:138465479..138469303

AA seq 543 aa
MAAAKAEMQLMSPLQISDPFGSFPHSPTMDNYPKLEEMMLLSNGAPQFLGAAGAPEGSGS
NSSSSSSGGGGGGGGGSNSSSSSSTFNPQADTGEQPYEHLTAESFPDISLNNEKVLVETS
YPSQTTRLPPITYTGRFSLEPAPNSGNTLWPEPLFSLVSGLVSMTNPPASSSSAPSPAAS
SASASQSPPLSCAVPSNDSSPIYSAAPTFPTPNTDIFPEPQSQAFPGSAGTALQYPPPAY
PAAKGGFQVPMIPDYLFPQQQGDLGLGTPDQKPFQGLESRTQQPSLTPLSTIKAFATQSG
SQDLKALNTSYQSQLIKPSRMRKYPNRPSKTPPHERPYACPVESCDRRFSRSDELTRHIR
IHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLR
QKDKKADKSVVASSATSSLSSYPSPVATSYPSPVTTSYPSPATTSYPSPVPTSFSSPGSS
TYPSPVHSGFPSPSVATTYSSVPPAFPAQVSSFPSSAVTNSFSASTGLSDMTATFSPRTI
EIC

NT seq 1632 nt +upstreamnt +downstreamnt
atggccgcggccaaggccgagatgcagctgatgtccccgctgcagatctctgacccgttc
ggatcctttcctcactcgcccaccatggacaactaccctaagctggaggagatgatgctg
ctgagcaacggggctccccagttcctcggcgccgccggggccccagagggcagcggcagc
aacagcagcagcagcagcagcgggggcggtggaggcggcgggggcggcagcaacagcagc
agcagcagcagcaccttcaaccctcaggcggacacgggcgagcagccctacgagcacctg
accgcagagtcttttcctgacatctctctgaacaacgagaaggtgctggtggagaccagt
taccccagccaaaccactcgactgccccccatcacctatactggccgcttttccctggag
cctgcacccaacagtggcaacaccttgtggcccgagcccctcttcagcttggtcagtggc
ctagtgagcatgaccaacccaccggcctcctcgtcctcagcaccatctccagcggcctcc
tccgcctccgcctcccagagcccacccctgagctgcgcagtgccatccaacgacagcagt
cccatttactcagcggcacccaccttccccacgccgaacactgacattttccctgagcca
caaagccaggccttcccgggctcggcagggacagcgctccagtacccgcctcctgcctac
cctgccgccaagggtggcttccaggttcccatgatccccgactacctgtttccacagcag
cagggggatctgggcctgggcaccccagaccagaagcccttccagggcctggagagccgc
acccagcagccttcgctaacccctctgtctactattaaggcctttgccactcagtcgggc
tcccaggacctgaaggccctcaataccagctaccagtcccagctcatcaaacccagccgc
atgcgcaagtaccccaaccggcccagcaagacgcccccccacgaacgcccttacgcttgc
ccagtggagtcctgtgatcgccgcttctcccgctccgacgagctcacccgccacatccgc
atccacacaggccagaagcccttccagtgccgcatctgcatgcgcaacttcagccgcagc
gaccacctcaccacccacatccgcacccacacaggcgaaaagcccttcgcctgcgacatc
tgtggaagaaagtttgccaggagcgatgaacgcaagaggcataccaagatccacttgcgg
cagaaggacaagaaagcagacaaaagtgttgtggcctcttcggccacctcctctctctct
tcctacccgtccccggttgctacctcttacccgtccccggttactacctcttatccatcc
ccggccaccacctcatacccatcccctgtgcccacctccttctcctctcccggctcctcg
acctacccatcccctgtgcacagtggcttcccctccccgtcggtggccaccacgtactcc
tctgttccccctgctttcccggcccaggtcagcagcttcccttcctcagctgtcaccaac
tccttcagcgcctccacagggctttcggacatgacagcaaccttttctcccaggacaatt
gaaatttgctaa

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