| Entry |
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| Name |
HTLV-1 Tax to SRF-mediated transcription
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| Definition |
TAX -> SRF => (FOS,FOSL1,EGR1,EGR2) |
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| Expanded |
K21857 -> 6722 => (2353,8061,1958,1959) |
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| Class |
nt06160 Human T-cell leukemia virus 1 (HTLV-1)
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| Type |
Pathogen
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| Pathway |
| hsa05166 | Human T-cell leukemia virus 1 infection |
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| Disease |
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| Gene |
| 6722 | SRF; serum response factor |
| 2353 | FOS; Fos proto-oncogene, AP-1 transcription factor subunit |
| 8061 | FOSL1; FOS like 1, AP-1 transcription factor subunit |
| 1958 | EGR1; early growth response 1 |
| 1959 | EGR2; early growth response 2 |
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|---|
| Perturbant |
| K21857 (TAX) | tax; HTLV protein Tax-1 |
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| Reference |
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| Authors |
Fujii M, Tsuchiya H, Chuhjo T, Akizawa T, Seiki M |
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| Title |
Interaction of HTLV-1 Tax1 with p67SRF causes the aberrant induction of cellular immediate early genes through CArG boxes. |
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| Journal |
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| Reference |
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| Authors |
Boxus M, Twizere JC, Legros S, Dewulf JF, Kettmann R, Willems L |
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| Title |
The HTLV-1 Tax interactome. |
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| Journal |
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| Reference |
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| Authors |
Azran I, Schavinsky-Khrapunsky Y, Aboud M |
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| Title |
Role of Tax protein in human T-cell leukemia virus type-I leukemogenicity. |
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| Journal |
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| LinkDB |
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