KEGG T01001: 1978

Homo sapiens (human): 1978

Entry

1978              CDS       T01001

Symbol

EIF4EBP1, 4E-BP1, 4EBP1, BP-1, PHAS-I

Name

(RefSeq) eukaryotic translation initiation factor 4E binding protein 1

K07205

eukaryotic translation initiation factor 4E binding protein 1

Organism

hsa Homo sapiens (human)

Pathway

hsa01521

EGFR tyrosine kinase inhibitor resistance

hsa04012

ErbB signaling pathway

hsa04066

HIF-1 signaling pathway

hsa04150

mTOR signaling pathway

hsa04151

PI3K-Akt signaling pathway

hsa04152

AMPK signaling pathway

hsa04211

Longevity regulating pathway

hsa04218

Cellular senescence

hsa04910

Insulin signaling pathway

hsa05163

Human cytomegalovirus infection

hsa05165

Human papillomavirus infection

hsa05168

Herpes simplex virus 1 infection

hsa05207

Chemical carcinogenesis - receptor activation

hsa05221

Acute myeloid leukemia

hsa05231

Choline metabolism in cancer

Network

nt06166  Human papillomavirus (HPV)
nt06167  Human cytomegalovirus (HCMV)
nt06168  Herpes simplex virus 1 (HSV-1)

Element

N00582

IGF-IGF1R-PI3K signaling pathway

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    1978 (EIF4EBP1)
   04151 PI3K-Akt signaling pathway
    1978 (EIF4EBP1)
   04152 AMPK signaling pathway
    1978 (EIF4EBP1)
   04150 mTOR signaling pathway
    1978 (EIF4EBP1)
09150 Organismal Systems
  09149 Aging
   04211 Longevity regulating pathway
    1978 (EIF4EBP1)
09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    1978 (EIF4EBP1)
   05231 Choline metabolism in cancer
    1978 (EIF4EBP1)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    1978 (EIF4EBP1)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    1978 (EIF4EBP1)
   05165 Human papillomavirus infection
    1978 (EIF4EBP1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    1978 (EIF4EBP1)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    1978 (EIF4EBP1)
Messenger RNA biogenesis [BR:hsa03019]
Eukaryotic type
  mRNA surveillance and transport factors
   Transport factors
    eIF4F and regulatory proteins
     1978 (EIF4EBP1)

SSDB

Motif

Pfam:

eIF_4EBP

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Structure

LinkDB

Position

8:38030534..38060365

AA seq 118 aa
MSGGSSCSQTPSRAIPATRRVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTRIIYDRKFLM
ECRNSPVTKTPPRDLPTIPGVTSPSSDEPPMEASQSHLRNSPEDKRAGGEESQFEMDI

NT seq 357 nt +upstreamnt +downstreamnt
atgtccgggggcagcagctgcagccagaccccaagccgggccatccccgccactcgccgg
gtggtgctcggcgacggcgtgcagctcccgcccggggactacagcacgacccccggcggc
acgctcttcagcaccaccccgggaggtaccaggatcatctatgaccggaaattcctgatg
gagtgtcggaactcacctgtgaccaaaacacccccaagggatctgcccaccattccgggg
gtcaccagcccttccagtgatgagccccccatggaagccagccagagccacctgcgcaat
agcccagaagataagcgggcgggcggtgaagagtcacagtttgagatggacatttaa

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