Homo sapiens (human): 2072
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Entry
2072 CDS
T01001
Symbol
ERCC4, ERCC11, FANCQ, RAD1, XFEPS, XPF
Name
(RefSeq) ERCC excision repair 4, endonuclease catalytic subunit
KO
K10848
DNA excision repair protein ERCC-4 [EC:3.1.-.-]
Organism
hsa
Homo sapiens (human)
Pathway
hsa03420
Nucleotide excision repair
hsa03460
Fanconi anemia pathway
Network
nt06502
Nucleotide excision repair
nt06508
Interstrand crosslink repair
Element
N01431
Core NER reaction
N01465
Lesion bypass by TLS and DSB formation
Disease
H00076
Cockayne syndrome
H00238
Fanconi anemia
H00403
Disorders of nucleotide excision repair
H01428
Xeroderma pigmentosum
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09124 Replication and repair
03420 Nucleotide excision repair
2072 (ERCC4)
03460 Fanconi anemia pathway
2072 (ERCC4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
hsa03032
]
2072 (ERCC4)
03400 DNA repair and recombination proteins [BR:
hsa03400
]
2072 (ERCC4)
DNA replication proteins [BR:
hsa03032
]
Eukaryotic type
DNA Replication Termination Factors
Other termination factors
2072 (ERCC4)
DNA repair and recombination proteins [BR:
hsa03400
]
Eukaryotic type
SSBR (single strand breaks repair)
NER (nucleotide excision repair)
Other NER factors
2072 (ERCC4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ERCC4
HHH_5
LUC7
Motif
Other DBs
NCBI-GeneID:
2072
NCBI-ProteinID:
NP_005227
OMIM:
133520
HGNC:
3436
Ensembl:
ENSG00000175595
UniProt:
Q92889
A0A1W1GSK9
Structure
PDB
PDBj
LinkDB
All DBs
Position
16:13920154..13952348
Genome browser
AA seq
916 aa
AA seq
DB search
MESGQPARRIAMAPLLEYERQLVLELLDTDGLVVCARGLGADRLLYHFLQLHCHPACLVL
VLNTQPAEEEYFINQLKIEGVEHLPRRVTNEITSNSRYEVYTQGGVIFATSRILVVDFLT
DRIPSDLITGILVYRAHRIIESCQEAFILRLFRQKNKRGFIKAFTDNAVAFDTGFCHVER
VMRNLFVRKLYLWPRFHVAVNSFLEQHKPEVVEIHVSMTPTMLAIQTAILDILNACLKEL
KCHNPSLEVEDLSLENAIGKPFDKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQ
YDCVTFLNLLESLRATEKAFGQNSGWLFLDSSTSMFINARARVYHLPDAKMSKKEKISEK
MEIKEGEETKKELVLESNPKWEALTEVLKEIEAENKESEALGGPGQVLICASDDRTCSQL
RDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERAST
KERTLKKKKRKLTLTQMVGKPEELEEEGDVEEGYRREISSSPESCPEEIKHEEFDVNLSS
DAAFGILKEPLTIIHPLLGCSDPYALTRVLHEVEPRYVVLYDAELTFVRQLEIYRASRPG
KPLRVYFLIYGGSTEEQRYLTALRKEKEAFEKLIREKASMVVPEEREGRDETNLDLVRGT
ASADVSTDTRKAGGQEQNGTQQSIVVDMREFRSELPSLIHRRGIDIEPVTLEVGDYILTP
EMCVERKSISDLIGSLNNGRLYSQCISMSRYYKRPVLLIEFDPSKPFSLTSRGALFQEIS
SNDISSKLTLLTLHFPRLRILWCPSPHATAELFEELKQSKPQPDAATALAITADSETLPE
SEKYNPGPQDFLLKMPGVNAKNCRSLMHHVKNIAELAALSQDELTSILGNAANAKQLYDF
IHTSFAEVVSKGKGKK
NT seq
2751 nt
NT seq
+upstream
nt +downstream
nt
atggagtcagggcagccggctcgacggattgccatggcgccgctgctggagtacgagcga
cagctggtgctggaactgctcgacactgacgggctagtagtgtgcgcccgcgggctcggc
gcggaccggctcctctaccactttctccagctgcactgccacccagcctgcctggtgctg
gtgctcaacacgcagccggccgaggaggagtattttatcaatcagctgaagatagaagga
gttgaacacctccctcgccgtgtaacaaatgaaatcacaagcaacagtcgctatgaagtt
tacacacaaggtggtgttatatttgcgacaagtaggatacttgtggttgacttcttgact
gatagaataccttcagatttaattactggcatcttggtgtatagagcccacagaataatc
gagtcttgtcaagaagcattcatcttgcgcctctttcgccagaaaaacaaacgtggtttt
attaaagctttcacagacaatgctgttgcctttgatactggtttttgtcatgtggaaaga
gtgatgagaaatctttttgtgaggaaactgtatctgtggccaaggttccatgtagcagta
aactcatttttagaacagcacaaacctgaagttgtagaaatccatgtttctatgacacct
accatgcttgctatacagactgctatactggacattttaaatgcatgtctaaaggaacta
aaatgccataacccatcgcttgaagtggaagatttatctttagaaaatgctattggaaaa
ccttttgacaagacaatccgccattatctggatcctttgtggcaccagcttggagccaag
actaaatccttagttcaggatttgaagatattacgaactttgctgcagtatctctctcag
tatgattgtgtcacatttcttaatcttctggaatctctgagagcaacggaaaaagctttt
ggtcagaattcaggttggctgtttcttgactccagcacctcgatgtttataaatgctcga
gcaagggtttatcatcttccagatgccaaaatgagtaaaaaagaaaaaatatctgaaaaa
atggaaattaaagaaggggaagaaacaaaaaaggaactggtcctagaaagcaacccaaag
tgggaggcactgactgaagtattaaaagaaattgaggcagaaaataaggagagtgaagct
cttggtggtccaggtcaagtactgatttgtgcaagtgatgaccgaacatgttcccagctg
agagactatatcactcttggagcggaggccttcttattgaggctctacaggaaaaccttt
gagaaggatagcaaagctgaagaagtctggatgaaatttaggaaggaagacagttcaaag
agaattaggaaatctcacaaaagacctaaagacccccaaaacaaagaacgggcttctacc
aaagaaagaaccctcaaaaagaaaaaacggaagttgaccttaactcaaatggtaggaaaa
cctgaagaactggaagaggaaggagatgtcgaggaaggatatcgtcgagaaataagcagt
agcccagaaagctgcccggaagaaattaagcatgaagaatttgatgtaaatttgtcatcg
gatgctgctttcggaatcctgaaagaacccctcactatcatccatccgcttctgggttgc
agcgacccctatgctctgacaagggtactacatgaagtggagccaagatacgtggttctt
tatgacgcagagctaacctttgttcggcagcttgaaatttacagggcgagtaggcctggg
aaacctctgagggtttactttcttatatacggaggttcaactgaggaacaacgctatctc
actgctttgcggaaagaaaaggaagcttttgaaaaactcataagggaaaaagcaagcatg
gttgtccctgaagaaagagaaggcagagatgaaacaaacttagacctagtaagaggcaca
gcatctgcagatgtttccactgacactcggaaagccggtggccaggaacagaatggtaca
cagcaaagcatagttgtggatatgcgtgaatttcgaagtgagcttccatctctgatccat
cgtcggggcattgacattgaacccgtgactttagaggttggagattacatcctcactcca
gaaatgtgcgtggagcgcaagagtatcagtgatttaatcggctctttaaataacggccgc
ctctacagccagtgcatctccatgtcccgctactacaagcgtcccgtgcttctgattgag
tttgaccctagcaagcctttctctctcacttcccgaggtgccttgtttcaggagatctcc
agcaatgacattagttccaaactcactcttcttacacttcacttccccagactacggatt
ctctggtgcccctctcctcatgcaacggcggagttgtttgaggagctgaaacaaagcaag
ccacagcctgatgcggcgacagcactggccattacagcagattctgaaacccttcccgag
tcagagaagtataatcctggtccccaagacttcttgttaaaaatgccaggggtgaatgcc
aaaaactgccgctccttgatgcaccacgttaagaacatcgcagaattagcagccctgtca
caagacgagctcacgagtattctggggaatgctgcaaatgccaaacagctttatgatttc
attcacacctcttttgcagaagtcgtatcaaaaggaaaagggaaaaagtga
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