| Entry |
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| Name |
Lesion bypass by TLS and DSB formation
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| Definition |
FANCD2+FANCI+Ub -> FAN1 == SLX+MUS81+EME1 == ERCC4+ERCC1+SNM1A -> REV1,REV3L,REV7 |
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| Expanded |
2177+55215+7314 -> 22909 == 84464+548593+79008+80198+146956 == 2072+2067+9937 -> 51455,5980,10459 |
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| Class |
nt06508 Interstrand crosslink repair
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| Type |
Reference
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| Pathway |
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| Gene |
| 2177 | FANCD2; FA complementation group D2 |
| 55215 | FANCI; FA complementation group I |
| 22909 | FAN1; FANCD2 and FANCI associated nuclease 1 |
| 84464 | SLX4; SLX4 structure-specific endonuclease subunit |
| 548593 | SLX1A; SLX1 homolog A, structure-specific endonuclease subunit |
| 79008 | SLX1B; SLX1 homolog B, structure-specific endonuclease subunit |
| 80198 | MUS81; MUS81 structure-specific endonuclease subunit |
| 146956 | EME1; essential meiotic structure-specific endonuclease 1 |
| 2072 | ERCC4; ERCC excision repair 4, endonuclease catalytic subunit |
| 2067 | ERCC1; ERCC excision repair 1, endonuclease non-catalytic subunit |
| 9937 | DCLRE1A; DNA cross-link repair 1A |
| 51455 | REV1; REV1 DNA directed polymerase |
| 5980 | REV3L; REV3 like, DNA directed polymerase zeta catalytic subunit |
| 10459 | MAD2L2; mitotic arrest deficient 2 like 2 |
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| Reference |
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| Authors |
Michl J, Zimmer J, Tarsounas M |
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| Title |
Interplay between Fanconi anemia and homologous recombination pathways in genome integrity. |
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| Journal |
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| Reference |
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| Authors |
Ceccaldi R, Sarangi P, D'Andrea AD |
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| Title |
The Fanconi anaemia pathway: new players and new functions. |
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| Journal |
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| Reference |
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| Authors |
Basbous J, Constantinou A |
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| Title |
A tumor suppressive DNA translocase named FANCM. |
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| Journal |
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| LinkDB |
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