KEGG   DRUG: Tifacogin
Entry
D06142                      Drug                                   

Name
Tifacogin (USAN/INN)
Formula
C1400H2167N395O422S23
Exact mass
32000.3827
Mol weight
32021.0743
Sequence
ADSEEDEEHT IITDTELPPL KLMHSFCAFK ADDGPCKAIM KRFFFNIFTR QCEEFIYGGC
EGNQNRFESL EECKKMCTRD NANRIIKTTL QQEKPDFCFL EEDPGICRGY ITRYFYNNQT
KQCERFKYGG CLGNMNNFET LEECKNICED GPNGFQVDNY GTQLNAVNNS LTPQSTKVPS
LFEFHGPSWC LTPADRGLCR ANENRFYYNS VIGKCRPFKY SGCGGNENNF TSKQECLRAC
KKGFIQRISK GGLIKTKRKR KKQRVKIAYE EIFVKNM
  Type
Peptide
Class
Cardiovascular agent
 DG01662  Factor Xa inhibitor
 DG01950  Antithrombotic agent
  DG01707  Fibrinolytic
  DG01662  Factor Xa inhibitor
 DG01707  Fibrinolytic
Efficacy
Anticoagulant, Lipoprotein associated coagulation inhibitor
Comment
recombinant tissue factor pathway inhibitor [HSA:7035] [KO:K03909]
Target
F3 (CD142) [HSA:2152] [KO:K03901]
F10 [HSA:2159] [KO:K01314]
  Pathway
hsa04610  Complement and coagulation cascades
Interaction
Brite
Target-based classification of drugs [BR:br08310]
 Cell surface molecules and ligands
  Other cell surface molecules
   CD molecules
    F3 (CD142)
     D06142  Tifacogin (USAN/INN)
 Enzymes
  Hydrolases (EC3)
   Serine peptidases
    F10
     D06142  Tifacogin (USAN/INN)
Other DBs
CAS: 148883-56-1
PubChem: 47207800
LinkDB

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