Homo sapiens (human): 2237
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Entry
2237 CDS
T01001
Symbol
FEN1, FEN-1, MF1, RAD2
Name
(RefSeq) flap structure-specific endonuclease 1
KO
K04799
flap endonuclease-1 [EC:3.1.-.-]
Organism
hsa
Homo sapiens (human)
Pathway
hsa03030
DNA replication
hsa03410
Base excision repair
hsa03450
Non-homologous end-joining
Network
nt06504
Base excision repair
nt06509
DNA replication
Element
N01436
Long patch BER
N01472
Okazaki fragment maturation
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09124 Replication and repair
03030 DNA replication
2237 (FEN1)
03410 Base excision repair
2237 (FEN1)
03450 Non-homologous end-joining
2237 (FEN1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
hsa03032
]
2237 (FEN1)
03400 DNA repair and recombination proteins [BR:
hsa03400
]
2237 (FEN1)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
2237 (FEN1)
DNA replication proteins [BR:
hsa03032
]
Eukaryotic type
DNA Replication Elongation Factors
Other elongation factors
2237 (FEN1)
Prokaryotic type
Elongation factors (archaeal)
Other elongation factors
2237 (FEN1)
DNA repair and recombination proteins [BR:
hsa03400
]
Eukaryotic type
SSBR (single strand breaks repair)
BER (base exicision repair)
Long Patch-BER factors
2237 (FEN1)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
2237 (FEN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
XPG_N
XPG_I
5_3_exonuc
XPG_I_2
HHH_5
DUF3560
Maelstrom
Motif
Other DBs
NCBI-GeneID:
2237
NCBI-ProteinID:
NP_004102
OMIM:
600393
HGNC:
3650
Ensembl:
ENSG00000168496
Pharos:
P39748
(Tchem)
UniProt:
P39748
Q6FHX6
Structure
PDB
PDBj
LinkDB
All DBs
Position
11:61792911..61797238
Genome browser
AA seq
380 aa
AA seq
DB search
MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGET
TSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQAAGAE
QEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDM
DCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCESIRG
IGPKRAVDLIQKHKSIEEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVELKWSE
PNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSLSSAKRKEPEP
KGSTKKKAKTGAAGKFKRGK
NT seq
1143 nt
NT seq
+upstream
nt +downstream
nt
atgggaattcaaggcctggccaaactaattgctgatgtggcccccagtgccatccgggag
aatgacatcaagagctactttggccgtaaggtggccattgatgcctctatgagcatttat
cagttcctgattgctgttcgccagggtggggatgtgctgcagaatgaggagggtgagacc
accagccacctgatgggcatgttctaccgcaccattcgcatgatggagaacggcatcaag
cccgtgtatgtctttgatggcaagccgccacagctcaagtcaggcgagctggccaaacgc
agtgagcggcgggctgaggcagagaagcagctgcagcaggctcaggctgctggggccgag
caggaggtggaaaaattcactaagcggctggtgaaggtcactaagcagcacaatgatgag
tgcaaacatctgctgagcctcatgggcatcccttatcttgatgcacccagtgaggcagag
gccagctgtgctgccctggtgaaggctggcaaagtctatgctgcggctaccgaggacatg
gactgcctcaccttcggcagccctgtgctaatgcgacacctgactgccagtgaagccaaa
aagctgccaatccaggaattccacctgagccggattctgcaggagctgggcctgaaccag
gaacagtttgtggatctgtgcatcctgctaggcagtgactactgtgagagtatccggggt
attgggcccaagcgggctgtggacctcatccagaagcacaagagcatcgaggagatcgtg
cggcgacttgaccccaacaagtaccctgtgccagaaaattggctccacaaggaggctcac
cagctcttcttggaacctgaggtgctggacccagagtctgtggagctgaagtggagcgag
ccaaatgaagaagagctgatcaagttcatgtgtggtgaaaagcagttctctgaggagcga
atccgcagtggggtcaagaggctgagtaagagccgccaaggcagcacccagggccgcctg
gatgatttcttcaaggtgaccggctcactctcttcagctaagcgcaaggagccagaaccc
aagggatccactaagaagaaggcaaagactggggcagcagggaagtttaaaaggggaaaa
taa
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