Homo sapiens (human): 22909
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Entry
22909 CDS
T01001
Symbol
FAN1, KIAA1018, KMIN, MTMR15, hFAN1
Name
(RefSeq) FANCD2 and FANCI associated nuclease 1
KO
K15363
fanconi-associated nuclease 1 [EC:3.1.21.-
3.1.4.1
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa03460
Fanconi anemia pathway
Network
nt06508
Interstrand crosslink repair
Element
N01465
Lesion bypass by TLS and DSB formation
Disease
H01877
Chromosome 15q13.3 microdeletion syndrome
H02577
Karyomegalic interstitial nephritis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09124 Replication and repair
03460 Fanconi anemia pathway
22909 (FAN1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03400 DNA repair and recombination proteins [BR:
hsa03400
]
22909 (FAN1)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.1 phosphodiesterase I
22909 (FAN1)
DNA repair and recombination proteins [BR:
hsa03400
]
Eukaryotic type
DSBR (double strand breaks repair)
FA (Fanconi anemia) pathway
Other FA pathway factors
22909 (FAN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
FAN1_TPR
Fan1_SAP
VRR_NUC
FAN1_HTH
DUF4363
zf-TRAF
zf-WRNIP1_ubi
EPTP
Motif
Other DBs
NCBI-GeneID:
22909
NCBI-ProteinID:
NP_055782
OMIM:
613534
HGNC:
29170
Ensembl:
ENSG00000198690
UniProt:
Q9Y2M0
Structure
PDB
PDBj
LinkDB
All DBs
Position
15:30903852..30943108
Genome browser
AA seq
1017 aa
AA seq
DB search
MMSEGKPPDKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRHL
DEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKRE
VKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGSS
PQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEAE
SQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREACH
CEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQG
SSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVR
LFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSL
AKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKG
PRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRD
DLIRYAAATHMLSDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCF
TVGWIYTRILSRFVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLK
RLEPTIKCITEGLADPEVRTGHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHV
TITGRLCPQRGMCKSVFVMEAGEAADPTTVLCSVEELALAHYRRSGFDQGIHGEGSTFST
LYGLLLWDIIFMDGIPDVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRA
WVAATWHEQEGRVASLVSWDRFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPD
LVVWNSQSRHFKLVEVKGPNDRLSHKQMIWLAELQKLGAEVEVCHVVAVGAKSQSLS
NT seq
3054 nt
NT seq
+upstream
nt +downstream
nt
atgatgtcagaagggaaacctcctgacaaaaaaaggcctcgtagaagcttatcaatcagc
aagaataagaaaaaagcatctaattctattatttcgtgttttaacaatgcaccacctgct
aaacttgcctgccccgtttgcagtaaaatggtgcctagatatgacttaaaccggcacctt
gatgaaatgtgtgctaacaatgacttcgttcaagtggatccagggcaggttggcttaata
aattcaaatgtgtctatggtagatttaaccagtgttaccttagaagatgtaacacctaag
aagtcaccaccaccaaagacaaatttaacccctggccaaagtgattcagcaaaaagggaa
gtaaagcagaagatcagtccctactttaaaagtaatgatgtggtgtgcaaaaatcaagat
gagctgagaaatcgtagtgtgaaagtcatttgtttgggaagcctagcatctaaattgtcc
agaaaatacgtaaaggctaaaaaatcaatagataaggatgaagaatttgccggttctagt
ccacagagttccaaatccacagttgttaagagcctgattgataactcttcagaaattgag
gacgaggatcaaattttggagaacagttctcaaaaagaaaacgtgtttaaatgtgattct
ctaaaggaagagtgcattcctgaacatatggtaagaggaagtaaaataatggaagccgaa
agccaaaaggctacccgggaatgtgagaaatcagccctcacccctggattctcagataat
gcgatcatgttattctcaccagatttcactcttaggaatacattaaagtctacttcagaa
gacagtcttgtaaagcaagagtgtatcaaagaagtggttgaaaaacgtgaggcatgtcat
tgtgaagaagtaaaaatgactgttgcttcagaagctaaaatacagctgtcagattcagag
gcaaaatctcatagttctgcagatgatgcttctgcatggagtaacatccaagaggctcct
ctgcaggatgacagttgcttaaacaatgatatccctcacagcattcctttggagcagggg
tcaagctgcaatggtcctggtcaaacaaccggtcatccttactaccttcggagtttcctt
gtggtgctgaaaaccgtacttgagaatgaagatgatatgttgctctttgatgagcaggag
aagggaattgtaactaaattttatcagttatcagctactggtcagaagttatatgtaagg
ctctttcaacgtaaattaagctggattaagatgaccaaattagagtatgaagagattgcc
ttagacttaacacctgtgattgaagaattgacgaatgcaggctttctacagacagaatct
gagttgcaagaactctctgaagtgcttgaactcctttctgctcctgaactaaaatcccta
gccaagaccttccacttggtgaatcccaatggacagaaacagcagctggtggacgccttt
ctcaaattggccaaacagcgttcagtctgcacttggggcaagaataagcctggaattggt
gcagtgattttaaaaagagccaaagccttggctggacagtcagtacgaatctgtaaaggc
cccagggctgtgttttcccgcatcttgctactgttttcgttgaccgactcaatggaagat
gaagacgccgcttgtggaggtcagggacagctttcaacagtcctgttggtcaacctcggc
cgaatggagtttcctagttacaccatcaatcggaaaacccacatcttccaagacagagat
gatcttatcagatatgcagcagccacgcacatgctgagtgacatttcttccgcaatggcc
aatgggaactgggaagaagctaaggagctcgctcagtgtgcaaaaagggattggaacaga
ctgaaaaaccacccttctctgagatgccacgaagatttaccactcttcctgcggtgtttc
actgttgggtggatttatacaaggattttgtctcggtttgtggaaatactgcagagactt
cacatgtatgaggaagccgtcagagaacttgaaagccttttgtctcagagaatttattgt
cctgacagcagaggccgatggtgggatcgactggcccttaatttacaccagcacttgaag
cgcctggaaccgactatcaagtgcatcacagaggggctggcggatccggaagtcagaacg
ggacaccgcctttcactgtatcagcgagccgtgcgcctgcgagagtctccgagctgtaaa
aagttcaagcacctcttccagcagctcccagaaatggctgtgcaagatgtgaaacacgtg
accatcacaggcaggctgtgcccacagcgtgggatgtgcaagtctgtgtttgtgatggag
gccggggaggccgctgaccccaccacggtcctgtgctctgtggaggagctggcactggcc
cattacagacgcagcggttttgaccaggggattcatggcgaagggtccaccttcagcacc
ctgtatggcctcctcctgtgggacatcatcttcatggatgggattccggatgtcttcaga
aacgcctgtcaggcattccccctggacttgtgcacagacagcttcttcacaagcagacgc
ccagcccttgaggccaggctgcagctgattcatgatgcccccgaggagagcctgcgggcc
tgggtggcagccacgtggcatgagcaggaaggcagagtggcttcccttgtcagctgggat
cgcttcacgtctcttcagcaagctcaggatcttgtctcctgcctggggggccctgtgctc
agtggtgtgtgcaggcacctggctgctgactttcgacactgtcgagggggcctccccgac
ctggtggtgtggaactcccagagccgtcactttaagctggtggaagttaaaggccccaat
gatcgtctttcacataagcagatgatctggctggctgaactgcagaagctgggggctgaa
gtagaagtctgccatgtggttgcagttggagctaagagccaaagccttagctaa
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integrated database retrieval system
