Homo sapiens (human): 22941
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Entry
22941 CDS
T01001
Symbol
SHANK2, AUTS17, CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3
Name
(RefSeq) SH3 and multiple ankyrin repeat domains 2
KO
K15009
SH3 and multiple ankyrin repeat domains protein
Organism
hsa
Homo sapiens (human)
Pathway
hsa04724
Glutamatergic synapse
Network
nt06544
Neuroactive ligand signaling
Element
N01880
GRM1/5-interacting scaffold proteins
Disease
H02111
Autism
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09156 Nervous system
04724 Glutamatergic synapse
22941 (SHANK2)
BRITE hierarchy
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Ank_2
Ank
SAM_1
SAM_2
Ank_4
Ank_3
Ank_5
SH3_2
PDZ_6
SH3_9
PDZ
FERM_f0
SH3_1
SAM_4
SAM_CEP-1_C
Motif
Other DBs
NCBI-GeneID:
22941
NCBI-ProteinID:
NP_036441
OMIM:
603290
HGNC:
14295
Ensembl:
ENSG00000162105
UniProt:
Q9UPX8
Structure
PDB
PDBj
LinkDB
All DBs
Position
11:complement(70467854..71253228)
Genome browser
AA seq
1849 aa
AA seq
DB search
MPRSPTSSEDEMAQSFSDYSVGSESDSSKEETIYDTIRATAEKPGGARTEESQGNTLVIR
VVIHDLQQTKCIRFNPDATVWVAKQRILCTLTQSLKDVLNYGLFQPASNGRDGKFLDEER
LLREYPQPVGEGVPSLEFRYKKRVYKQASLDEKQLAKLHTKTNLKKCMDHIQHRLVEKIT
KMLDRGLDPNFHDPETGETPLTLAAQLDDSVEVIKALKNGGAHLDFRAKDGMTALHKAAR
ARNQVALKTLLELGASPDYKDSYGLTPLYHTAIVGGDPYCCELLLHEHATVCCKDENGWH
EIHQACRYGHVQHLEHLLFYGADMSAQNASGNTALHICALYNQDSCARVLLFRGGNKELK
NYNSQTPFQVAIIAGNFELAEYIKNHKETDIVPFREAPAYSNRRRRPPNTLAAPRVLLRS
NSDNNLNASAPDWAVCSTATSHRSLSPQLLQQMPSKPEGAAKTIGSYVPGPRSRSPSLNR
LGGAGEDGKRPQPLWHVGSPFALGANKDSLSAFEYPGPKRKLYSAVPGRLFVAVKPYQPQ
VDGEIPLHRGDRVKVLSIGEGGFWEGSARGHIGWFPAECVEEVQCKPRDSQAETRADRSK
KLFRHYTVGSYDSFDTSSDCIIEEKTVVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFP
ALQYLESVDEGGVAWQAGLRTGDFLIEVNNENVVKVGHRQVVNMIRQGGNHLVLKVVTVT
RNLDPDDTARKKAPPPPKRAPTTALTLRSKSMTSELEELVDKASVRKKKDKPEEIVPASK
PSRAAENMAVEPRVATIKQRPSSRCFPAGSDMNSVYERQGIAVMTPTVPGSPKAPFLGIP
RGTMRRQKSIDSRIFLSGITEEERQFLAPPMLKFTRSLSMPDTSEDIPPPPQSVPPSPPP
PSPTTYNCPKSPTPRVYGTIKPAFNQNSAAKVSPATRSDTVATMMREKGMYFRRELDRYS
LDSEDLYSRNAGPQANFRNKRGQMPENPYSEVGKIASKAVYVPAKPARRKGMLVKQSNVE
DSPEKTCSIPIPTIIVKEPSTSSSGKSSQGSSMEIDPQAPEPPSQLRPDESLTVSSPFAA
AIAGAVRDREKRLEARRNSPAFLSTDLGDEDVGLGPPAPRTRPSMFPEEGDFADEDSAEQ
LSSPMPSATPREPENHFVGGAEASAPGEAGRPLNSTSKAQGPESSPAVPSASSGTAGPGN
YVHPLTGRLLDPSSPLALALSARDRAMKESQQGPKGEAPKADLNKPLYIDTKMRPSLDAG
FPTVTRQNTRGPLRRQETENKYETDLGRDRKGDDKKNMLIDIMDTSQQKSAGLLMVHTVD
ATKLDNALQEEDEKAEVEMKPDSSPSEVPEGVSETEGALQISAAPEPTTVPGRTIVAVGS
MEEAVILPFRIPPPPLASVDLDEDFIFTEPLPPPLEFANSFDIPDDRAASVPALSDLVKQ
KKSDTPQSPSLNSSQPTNSADSKKPASLSNCLPASFLPPPESFDAVADSGIEEVDSRSSS
DHHLETTSTISTVSSISTLSSEGGENVDTCTVYADGQAFMVDKPPVPPKPKMKPIIHKSN
ALYQDALVEEDVDSFVIPPPAPPPPPGSAQPGMAKVLQPRTSKLWGDVTEIKSPILSGPK
ANVISELNSILQQMNREKLAKPGEGLDSPMGAKSASLAPRSPEIMSTISGTRSTTVTFTV
RPGTSQPITLQSRPPDYESRTSGTRRAPSPVVSPTEMNKETLPAPLSAATASPSPALSDV
FSLPSQPPSGDLFGLNPAGRSRSPSPSILQQPISNKPFTTKPVHLWTKPDVADWLESLNL
GEHKEAFMDNEIDGSHLPNLQKEDLIDLGVTRVGHRMNIERALKQLLDR
NT seq
5550 nt
NT seq
+upstream
nt +downstream
nt
atgccgcgcagcccaacatccagcgaggacgagatggcccagagcttctccgactactcc
gtggggtcggagtcagacagctccaaagaagagaccatctatgacacgatccgggccact
gcggagaagccgggcggtgccaggacggaggagagccagggcaacacgctggtgatccgc
gtggtcatccatgacctgcagcagacgaaatgcattcgatttaacccggatgccacagtg
tgggttgcaaagcagcggatcctgtgtacattaacccagagtttgaaagatgtcctgaac
tacggcctgttccagccggccagcaatgggcgtgacggcaagttcctggatgaggagcgg
ctcctgcgcgagtacccacagcccgtgggtgagggcgttccttccctggagtttcgatac
aagaagcgggtgtataaacaagccagtctcgatgagaaacagttggccaagctccacacg
aagaccaatctgaagaaatgcatggatcacattcagcatcgcttggtggagaagatcacc
aagatgctggaccgaggcctggatcccaatttccacgacccggagaccggagagaccccc
ctgaccttagccgctcagctggacgactctgtggaggtcatcaaagctctcaaaaatggt
ggagctcacctggacttccgtgccaaagatgggatgaccgccctacacaaagctgcccga
gcgaggaaccaagttgccctgaagacccttttagagcttggtgcatccccagattataaa
gacagttacggcctcaccccgctgtatcacacagccatcgtcggaggtgatccctactgc
tgcgagcttctcctgcacgaacacgccactgtgtgctgcaaagatgagaacggctggcac
gagatccaccaggcctgcaggtacgggcacgtgcagcacctggagcacctgctgttctac
ggggcagacatgagtgcccagaatgcctcggggaacacggccttgcacatctgcgccctc
tacaaccaggacagctgtgcaagagtgcttctgtttcgaggcggaaataaggagttaaaa
aactacaacagccagactccatttcaggtggccataatagcaggcaactttgagctggca
gaatacatcaagaaccacaaggaaacagacattgtgcccttccgagaggccccggcgtac
tccaaccgccggcggcggccccccaacacgctggccgccccccgggtcctgctgcgctcc
aacagtgacaacaacctcaatgccagcgctcccgactgggccgtctgctccacggccacc
tcgcaccgcagcctgtcaccccagctgctgcagcagatgcccagcaagcccgagggggcc
gcgaagaccattgggagctacgtgcccgggccccgcagccggtccccatcgctcaacagg
ctgggcggcgcaggcgaggacggcaagaggccgcagcctctctggcatgtcgggtcgcct
tttgctcttggtgccaacaaggactcactctcggccttcgagtacccggggcccaagcgg
aagctctacagtgccgtgcccgggaggctcttcgtcgctgtcaagccataccaaccccaa
gtggacggcgagatcccccttcaccgcggtgacagggtcaaagttctgagcatcggtgaa
gggggcttctgggaaggcagcgcccgcggccacatcggatggtttccggcggagtgcgtg
gaggaggtccagtgtaagcccagggacagccaggcagaaacccgcgctgaccgcagcaag
aagcttttcaggcactacaccgtgggctcctatgacagcttcgacacttccagtgactgc
attattgaggagaagacggtggtcctgcagaaaaaagacaatgagggctttggattcgtg
cttcgaggggccaaagctgacacacccattgaagaattcacaccaacaccggctttccca
gccctacagtacctggagtccgtggatgaaggtggggtggcgtggcaagccggactaagg
accggggacttcttgattgaggttaacaatgagaatgttgtcaaagtcggccacaggcag
gtggtgaacatgatccggcagggagggaatcacctggtccttaaggtggtcacggtgacc
aggaatctggaccccgacgacaccgccaggaagaaagctcccccgcctccaaagcgggca
ccgaccacagccctcaccctgcgctccaagtccatgacctcggagctggaggagctcgtg
gataaagcctcggtccggaagaagaaggataaacccgaggagatagtcccggcctccaag
ccctcccgcgctgctgagaacatggctgtggaaccgagggtggcgaccatcaagcagcgg
cccagcagccggtgcttcccggcgggctcagacatgaactctgtgtacgaacgccaagga
atcgccgtgatgacgcccactgttcctgggagcccaaaagccccgtttctgggcatccct
cgaggtacgatgcgaaggcagaaatcaatagacagcagaatctttctatcaggaataaca
gaggaagagcggcagtttctggctcctccaatgctgaagttcaccagaagcctgtccatg
ccggacacctctgaggacatcccccctccaccgcagtctgtgcccccgtccccaccacca
ccttccccaaccacttacaactgccccaagtccccaactccaagagtctacgggacgatt
aagcctgcgttcaatcagaattctgccgccaaggtgtcccccgccaccaggtccgacacc
gtggccaccatgatgagggagaaggggatgtacttcaggagagagctggaccgctactcc
ttggactctgaagacctctacagtcggaatgccggcccgcaagccaacttccgcaacaag
agaggccagatgccagaaaacccatactcagaggtggggaagatcgccagcaaagccgtc
tacgtccccgccaagcccgccaggcggaaggggatgctggtgaagcagtccaacgtggag
gacagccccgagaagacgtgctccatccctatcccgaccatcatcgtgaaggagccgtcc
accagcagcagcggcaagagcagccagggcagcagcatggagatcgacccccaggccccg
gagccaccgagccagctgcggcctgacgaaagcctgaccgtcagcagcccctttgccgcc
gccatcgccggagccgtccgcgaccgtgagaagcggctggaagccaggaggaactccccg
gccttcctctccacagacctgggggatgaggatgtgggcctggggccacccgcccccagg
acgcggccctccatgttccccgaggagggggattttgctgacgaggacagcgctgagcag
ctgtcatcccccatgccgagtgccacgcccagggagcccgaaaaccatttcgtgggtggc
gccgaggccagtgctccgggtgaggctgggaggccgctgaattccacgtccaaagcccag
gggcccgagagcagcccagcagtgccctccgcgagcagcggcacagccggccccgggaat
tatgtccacccactcacagggcggctgcttgatcccagctccccgctggccctggcactc
tccgcaagggaccgagccatgaaggagtctcaacagggacccaaaggggaggcccccaag
gccgacctcaacaaacctctttacattgataccaaaatgcggcccagcctggatgccggc
ttccctacggtcaccaggcagaacacccggggacccctgaggcggcaggagacggagaac
aagtacgagaccgacctgggccgagaccggaaaggcgatgacaagaagaacatgctgatc
gacatcatggacacgtcccagcagaagtcggctggcctgctgatggtgcacaccgtggac
gccactaagctggacaacgccctgcaggaagaggacgagaaggcagaggtggagatgaag
ccagacagctcgccgtccgaggtgccagaaggtgtttccgaaaccgaaggtgctttacag
atctccgctgcccccgagcccaccaccgtgcccggcagaaccatcgtcgcggtgggctcc
atggaagaggcggtgattttgccattccgcatccctcctccccctctggcatccgtggac
ttggatgaggattttatttttacagagccattgcctcctcccctggaatttgcaaatagt
tttgatatccccgatgaccgggcagcttctgtcccggctctctcagacttagtgaagcag
aagaaaagcgacacccctcagtccccttcgttgaactccagccaaccaaccaactctgca
gacagcaagaagccagccagtctttcaaactgtctgcctgcctcattcctgccaccccct
gaaagctttgacgccgtcgccgactctgggatcgaggaggtggacagccggagtagcagc
gaccaccacctcgagacgaccagcactatctccaccgtgtctagcatctccaccctgtct
tccgaaggtggagagaatgtggacacctgcacagtctatgcagatgggcaagcatttatg
gttgacaaacccccagtacctcctaagccaaaaatgaagcccatcattcacaaaagcaat
gcactttatcaagacgcgctcgtggaagaagatgtagatagctttgttatccccccgccc
gctcccccgcccccgccgggcagtgcccagcctgggatggccaaggttctccagccaagg
acctccaagttgtggggcgacgtcacagagatcaaaagcccgattctctcaggcccaaag
gcaaacgttattagtgaattgaactctatcctacagcaaatgaaccgagagaaattggca
aagccgggggaaggactggattcaccaatgggagccaagtccgccagcctcgctccaaga
agcccggagatcatgagcaccatctcaggtacacggagcacgacggtcaccttcactgtt
cgccccggcacctcccagcccatcaccctgcagagccggccccccgactatgaaagcagg
acctcaggaacaagacgtgccccaagccctgtggtctcgccaacagagatgaacaaagag
accctgcccgcccccctgtctgctgccaccgcctctccttctcccgctctctcagatgtc
tttagccttccaagccagcccccttctggggatctatttggcttgaacccagcgggacgc
agtaggtcgccatccccctcgatactgcaacagccaatctcaaataagccttttacaact
aaacctgtccacctgtggactaaaccagatgtggccgattggctggaaagtctaaacttg
ggtgaacataaagaggccttcatggacaatgagatcgatggcagtcacttaccaaacctg
cagaaggaggacctcatcgatcttggggtaactcgagtcgggcacagaatgaacatagaa
agggctttgaaacagctgctggacagataa
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integrated database retrieval system
