| Entry |
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| Symbol |
KDM2A, CXXC8, FBL11, FBL7, FBXL11, JHDM1A, LILINA
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| Name |
(RefSeq) lysine demethylase 2A
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| KO |
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| Organism |
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09120 Genetic Information Processing
09126 Chromosome
03083 Polycomb repressive complex
22992 (KDM2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:hsa03000]
22992 (KDM2A)
04121 Ubiquitin system [BR:hsa04121]
22992 (KDM2A)
03036 Chromosome and associated proteins [BR:hsa03036]
22992 (KDM2A)
Enzymes [BR:hsa01000]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase
22992 (KDM2A)
Transcription factors [BR:hsa03000]
Eukaryotic type
Zinc finger
CXXC CpG-binding proteins
22992 (KDM2A)
Ubiquitin system [BR:hsa04121]
Ubiquitin ligases (E3)
Multi subunit type E3
SCF complex
Target recognizing subunit (F-box)
22992 (KDM2A)
Chromosome and associated proteins [BR:hsa03036]
Eukaryotic type
Histone modification proteins
Histone demethylases
22992 (KDM2A)
Polycomb repressive complex (PRC) and associated proteins
Noncanonical PRC1 (PRC1.1)
22992 (KDM2A)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
11:67119263..67258082
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| AA seq |
1162 aa
MEPEEERIRYSQRLRGTMRRRYEDDGISDDEIEGKRTFDLEEKLHTNKYNANFVTFMEGK
DFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCVGSRRMVDVMDVNTQKGIE
MTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKES
QTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHN
LELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFL
HSFNIPMQLKIYNIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKEFQKESLS
MDLELNGLESGNGDEEAVDREPRRLSSRRSVLTSPVANGVNLDYDGLGKTCRSLPSLKKT
LAGDSSSDCSRGSHNGQVWDPQCAPRKDRQVHLTHFELEGLRCLVDKLESLPLHKKCVPT
GIEDEDALIADVKILLEELANSDPKLALTGVPIVQWPKRDKLKFPTRPKVRVPTIPITKP
HTMKPAPRLTPVRPAAASPIVSGARRRRVRCRKCKACVQGECGVCHYCRDMKKFGGPGRM
KQSCVLRQCLAPRLPHSVTCSLCGEVDQNEETQDFEKKLMECCICNEIVHPGCLQMDGEG
LLNEELPNCWECPKCYQEDSSEKAQKRKMEESDEEAVQAKVLRPLRSCDEPLTPPPHSPT
SMLQLIHDPVSPRGMVTRSSPGAGPSDHHSASRDERFKRRQLLRLQATERTMVREKENNP
SGKKELSEVEKAKIRGSYLTVTLQRPTKELHGTSIVPKLQAITASSANLRHSPRVLVQHC
PARTPQRGDEEGLGGEEEEEEEEEEEDDSAEEGGAARLNGRGSWAQDGDESWMQREVWMS
VFRYLSRRELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKRQPVSLDLS
WTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALSTSSCPLLRTLDLRWAVGIKDPQIR
DLLTPPADKPGQDNRSKLRNMTDFRLAGLDITDATLRLIIRHMPLLSRLDLSHCSHLTDQ
SSNLLTAVGSSTRYSLTELNMAGCNKLTDQTLIYLRRIANVTLIDLRGCKQITRKACEHF
ISDLSINSLYCLSDEKLIQKIS |
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| NT seq |
3489 nt +upstreamnt +downstreamnt
atggaacccgaagaagaaaggattcgttacagccagagattgcgtggtaccatgcgacga
cgctatgaagatgatggcatttcagatgatgaaattgaaggaaaaagaacttttgacttg
gaagagaaactgcacaccaacaaatataatgccaattttgttacttttatggaaggaaaa
gattttaatgtagagtatattcagcggggtggcttgagagatcctctgattttcaagaat
tctgatggactcggaataaaaatgccggatccagacttcactgtgaatgatgtcaaaatg
tgtgtggggagtcgtcgcatggtggatgtcatggacgtgaacacacagaaaggcattgaa
atgaccatggctcagtggacacgctactatgagaccccagaggaggagcgagagaaactc
tataatgtcatcagcctcgagtttagccacaccaggctggagaatatggtgcagaggccc
tccacggtggatttcattgactgggtagacaacatgtggccaaggcacttgaaggaaagc
cagactgaatcaacaaatgccatcttggagatgcagtaccctaaagtgcagaagtactgt
ctaatgagtgttcgaggctgctatactgacttccatgtggactttggtggtacctctgtt
tggtatcacatccatcaagggggaaaggtcttctggctcatcccccctacagcccacaac
ctggagctgtacgagaattggctgctgtcagggaaacagggagacatctttctgggtgac
cgggtatcagattgtcagcgcattgagctcaagcagggctataccttcgtcattccctca
ggctggattcatgctgtgtatactcctacagacacattagtgtttgggggcaattttttg
catagcttcaacatccctatgcagttaaaaatatacaacattgaagatcggacacgggtt
ccaaataagtttcgctatccattctactatgagatgtgttggtatgtgttggagcgctat
gtgtactgcataaccaaccgttcccacctaactaaggaatttcagaaagagtccctcagc
atggatttggagttaaatgggttggagtctgggaatggggatgaggaagcagtggatcga
gaaccccgacgcttgagcagcaggcgttctgtcctcactagccctgtagcgaatggagtc
aacctggattatgatggactgggcaaaacctgccgaagtcttccaagtctgaagaaaact
ttggctggggactcatcttctgactgtagccggggctcccacaatggacaagtgtgggat
ccccagtgtgctccccgaaaggacaggcaagtgcatctgacccattttgagcttgaaggc
cttcgctgccttgtagataagttggagtctctgccactgcacaagaaatgtgtccccaca
gggatagaagatgaagatgctctcattgctgatgtaaagattttgctggaggagcttgcc
aacagcgatcccaagttagccctcactggagttcctatagtacagtggccaaaaagggat
aagcttaaattccccactcggccaaaggtgcgggttcctaccatccccattacgaagcct
cacactatgaaaccagctccacggttaacacctgtgaggccagctgctgcctccccgatt
gtgtcaggagccagacggagacgagtgcgatgtcgaaaatgcaaagcctgtgtgcaagga
gagtgtggtgtttgccactactgcagagacatgaagaagtttggggggcctggacgcatg
aagcagtcctgtgtcctccgacagtgcttggcacccagactgcctcactcagtcacatgt
tccctctgtggagaggtggatcagaatgaagagacacaagactttgagaagaaactcatg
gaatgctgtatctgcaatgagattgttcatcctggctgcctccagatggacggagagggg
ttgcttaacgaagaattgccaaattgctgggaatgtccaaagtgctaccaggaggacagc
tcggagaaagcccagaagcggaaaatggaagagagtgacgaagaagctgtgcaagccaaa
gtcctgcggcccctgcggagctgcgatgagcctctcacgcccccgcctcattcacccact
tccatgctgcagctcatccatgacccggtttccccccggggtatggtgactcggtcatcc
cctggggctggccccagcgaccaccacagtgccagccgcgatgagcgcttcaaacggcgg
cagttgctgcggctgcaggccacagagcgcaccatggtacgggaaaaggagaacaatccc
agcggcaaaaaggagctgtctgaagttgagaaagccaagatccggggatcgtacctcact
gtcacgctacagaggcccaccaaagagctccacgggacatccattgtgcccaagctgcag
gccatcacggcctcctctgccaaccttcgccattccccccgtgtgctagtgcagcactgc
ccagcccgaaccccccagcgtggggatgaggaggggctggggggagaggaggaggaagag
gaggaggaggaggaggaagatgacagtgcagaggaggggggtgcagccaggctgaatggc
cggggcagttgggctcaggatggagacgaaagctggatgcagcgggaggtctggatgtct
gtcttccgctacctcagccgcagagaactttgtgaatgtatgcgagtgtgcaagacgtgg
tataaatggtgctgcgacaagagactttggacaaaaattgacttgagtaggtgtaaggcc
attgtgccccaggccctcagtggcatcatcaagaggcagccagtcagccttgacctcagt
tggaccaacatctctaaaaagcaactgacatggctcgtcaataggctgccaggactgaaa
gacctcctcctagcaggctgctcctggtctgcagtctctgccctcagcacctccagctgc
ccccttctcaggacccttgatcttcggtgggcagtaggaatcaaggaccctcaaattcgg
gacttgcttactccaccggctgataaaccaggtcaggacaatcgcagcaagctccggaac
atgaccgacttccggctggcaggccttgacatcacagatgccacgcttcgcctcataatt
cgccacatgcccctcctgtctcgactcgacctcagtcactgcagccaccttacagatcag
tcctccaatctactcactgctgtcgggtcttccactcgctactctctcacagagctcaat
atggcaggttgcaataaattgacagaccagaccctgatctacctacggcgcattgccaac
gtcaccttgatcgaccttcgaggatgcaagcagatcactcgaaaagcctgcgagcacttc
atctcagacttgtccatcaacagcctctactgcctgtctgacgagaagctgatacagaag
atcagctaa |
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