Homo sapiens (human): 23020
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Entry
23020 CDS
T01001
Symbol
SNRNP200, ASCC3L1, BRR2, HELIC2, RP33, U5-200KD
Name
(RefSeq) small nuclear ribonucleoprotein U5 subunit 200
KO
K12854
pre-mRNA-splicing helicase BRR2 [EC:
5.6.2.6
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa03040
Spliceosome
Disease
H00527
Retinitis pigmentosa
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09121 Transcription
03040 Spliceosome
23020 (SNRNP200)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03041 Spliceosome [BR:
hsa03041
]
23020 (SNRNP200)
Enzymes [BR:
hsa01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.6 RNA 3'-5' helicase
23020 (SNRNP200)
Spliceosome [BR:
hsa03041
]
Complex B
U4/U6.U5 tri-snRNP components
U5 snRNP specific factors
23020 (SNRNP200)
Complex C
U5 SnRNP specific factors
23020 (SNRNP200)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Sec63
SNRNP200_wHTH
DEAD
Helicase_PWI
ResIII
Helicase_C
BRR2_plug
AAA_22
AAA_30
PhoH
SWI2_SNF2
DUF603
Motif
Other DBs
NCBI-GeneID:
23020
NCBI-ProteinID:
NP_054733
OMIM:
601664
HGNC:
30859
Ensembl:
ENSG00000144028
UniProt:
O75643
Structure
PDB
PDBj
LinkDB
All DBs
Position
2:complement(96274338..96305546)
Genome browser
AA seq
2136 aa
AA seq
DB search
MADVTARSLQYEYKANSNLVLQADRSLIDRTRRDEPTGEVLSLVGKLEGTRMGDKAQRTK
PQMQEERRAKRRKRDEDRHDINKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFI
QAALGDQPRDILCGAADEVLAVLKNEKLRDKERRKEIDLLLGQTDDTRYHVLVNLGKKIT
DYGGDKEIQNMDDNIDETYGVNVQFESDEEEGDEDVYGEVREEASDDDMEGDEAVVRCTL
SANLVASGELMSSKKKDLHPRDIDAFWLQRQLSRFYDDAIVSQKKADEVLEILKTASDDR
ECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSEAEKERIMGKMEADPELSKFL
YQLHETEKEDLIREERSRRERVRQSRMDTDLETMDLDQGGEALAPRQVLDLEDLVFTQGS
HFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKT
LNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIY
IAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKG
GERTYTQLVRLIILDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYED
VATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQ
VLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPY
GFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGR
WTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDM
LNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTA
ALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSL
SSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMAD
MVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVV
KKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKV
ELTITPDFQWDEKVHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFE
PLPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESL
YQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYIT
PMEALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWK
QRKNVQNINLFVVDEVHLIGGENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDV
AHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKKPVI
VFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYL
HEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYP
IYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEI
VTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSK
CISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPI
RHHEDNLLRQLAQKVPHKLNNPKFNDPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAI
RLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEHIKRCTDKGVE
SVFDIMEMEDEERNALLQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQ
LEREEEVTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKRLTLQQKAKVKLDFVAPATG
AHNYTLYFMSDAYMGCDQEYKFSVDVKEAETDSDSD
NT seq
6411 nt
NT seq
+upstream
nt +downstream
nt
atggcggatgtaaccgcccgtagtctgcaatacgagtacaaggcgaactcgaatcttgtg
ctccaagctgaccgttctctcattgaccggacccgccgggatgaacccacaggagaggtg
ctgtcccttgttgggaagctggagggcacccgtatgggagacaaggctcaacggaccaaa
ccgcagatgcaggaggaaagaagagccaagcgaagaaagcgtgatgaggaccggcatgac
atcaacaagatgaagggttatactctgctgtcggagggcattgatgagatggtgggcatc
atctacaagcccaaaactaaagagactcgggagacctatgaggtgctactcagcttcatc
caggctgctcttggggaccagccacgtgatatcctttgtggggcagctgatgaagttcta
gctgttctaaagaatgaaaagctgcgggacaaggaaaggcgaaaggagattgacctgctg
ctgggtcaaacagatgataccagataccatgtgctagtgaacctgggcaaaaagatcaca
gactatggtggagataaggaaatccaaaatatggatgacaacattgatgagacatacggt
gtgaatgtgcagtttgagtctgatgaggaggaaggtgatgaagacgtatacggggaggtt
cgagaagaggcatctgatgatgacatggaaggggacgaggctgtcgtgcgctgcaccctc
tcggctaatctcgtagcctcaggtgaactgatgagttccaagaagaaggatttgcaccct
cgggatattgatgcattttggctgcagcggcagctcagtcgtttctatgatgatgccatc
gtgtcgcagaagaaggcagatgaagtattggagattttgaagacggccagtgatgatcgg
gaatgtgaaaatcagctggttctgctgcttggtttcaacacctttgatttcattaaagtg
ttgcggcagcacaggatgatgattttatactgtaccttgctggccagtgcacaaagtgaa
gctgaaaaggaaaggattatgggaaagatggaagctgacccagagctatccaagttcctc
taccagcttcatgaaaccgagaaggaggatctgatccgagaggaaaggtcccggagagag
cgagtgcgtcagtctcgaatggacacagatctggaaaccatggatctcgaccagggtgga
gaggcactggctccacggcaggttctggacttggaggacctggtttttacccaagggagc
cactttatggccaataaacgctgtcagcttcctgatggatccttccgtcgccagcgtaag
ggctatgaagaggtgcatgtgcctgctctgaagcccaagccctttggctcagaagaacaa
ctgcttccagtggaaaagctgccaaagtatgcccaggctgggtttgagggcttcaaaaca
ctgaatcggatccagagtaagctctaccgtgctgcccttgagacggatgagaatctgctg
ctgtgtgctcctactggtgctgggaagaccaacgtggccctgatgtgcatgctccgagag
attgggaaacacataaacatggacggcaccatcaatgtggatgacttcaagattatctac
attgcccccatgcgctccttggtgcaggagatggtgggcagctttggaaagcgcctggcc
acttatggcatcactgttgctgaactgactggggaccaccagctgtgcaaagaagagatc
agtgccactcagatcatcgtctgcacccccgagaagtgggacatcatcacccgcaagggt
ggtgagcgcacctacacccagctggtgcggctcatcattctggatgagattcatcttctc
cacgatgacagaggtcctgtcttagaagctttagtggccagggccatccgaaacattgag
atgacccaagaggatgtccgactcattggtctcagtgccaccctacccaactatgaagat
gtagccacctttctacgtgttgaccctgccaagggtctcttttactttgacaacagcttc
cgtccagtgcctctggaacagacatatgtgggtatcacagagaaaaaagctatcaagcgt
ttccagatcatgaatgaaatcgtctatgaaaaaatcatggaacatgctggaaaaaatcag
gtgctggtgtttgtccactcccggaaggagactggaaagacagccagggccatccgggac
atgtgcctagaaaaggacactctgggtctgtttctgagggagggctcagcctccacagaa
gtcctgcgaacagaagctgagcagtgcaagaacctagagctgaaggatcttctgccttat
ggctttgctattcatcacgcaggcatgaccagggttgaccgaacactcgtggaggatctt
tttgctgataaacatattcaggttttagtttccacagcaactctagcttggggtgtgaat
ctccctgcacatacagtcatcatcaaaggcacccaggtgtacagtccagagaaggggcgt
tggacagaactgggagcactggacattctgcagatgctgggacgtgccggaagaccccag
tatgacaccaagggtgaaggcatactcatcacatctcatggggagctacagtactacctg
tccctcctcaatcaacaacttcctattgaaagccagatggtttcaaagcttcctgacatg
ctcaatgcagaaatcgtgctaggaaatgtccagaatgccaaggatgcggtgaactggctg
ggctatgcctacctctatatccgaatgctgcgatccccaaccctctatggcatctctcat
gatgacctcaagggagatcccctgctggaccagcgccgactagatctggttcatacagct
gccctgatgctggacaagaacaatctggtcaagtacgacaagaagacgggcaacttccag
gtgacagaactgggccgtatagccagccactactacatcaccaatgatacagtgcagact
tacaaccagctgctgaagcccaccctgagtgagattgagcttttcagggtcttctcattg
tcctctgagttcaagaacatcacagtgagagaggaggagaagctggagctgcagaagttg
ctggagagggtgcctatccctgtaaaggagagcattgaggaacccagtgctaagatcaac
gttcttctgcaagccttcatctcacagctgaaattggagggctttgcactgatggctgac
atggtgtatgtcacacagtcggctggccggttgatgcgagcgatatttgaaattgtcctg
aaccgaggttgggcacagcttacagacaagaccctgaacctctgcaagatgatcgacaaa
cgcatgtggcagtccatgtgtcctctgcgccagttccggaaactccctgaggaagtagtg
aagaagattgagaagaagaatttcccctttgagcgtctgtacgacctgaatcataatgag
attggggagcttatccgcatgccaaagatggggaagaccatccacaaatatgtccatctg
tttcccaagttggagttgtcagtgcacctgcagcctatcacacgctccaccctgaaggtg
gagctgaccatcacgccagacttccagtgggatgaaaaggtgcatggttcatccgaggct
ttttggattctggtggaggatgtggacagcgaggtgattctgcaccatgagtattttctc
ctcaaggccaagtacgcccaggacgagcacctcattacattcttcgtgcctgtctttgaa
ccgctgccccctcagtacttcatccgagtggtgtctgaccgctggctctcttgtgagacc
cagctgcctgtctccttccggcacctgatcttgccggagaagtacccccctccaaccgaa
cttttggacctgcagcccttgcccgtgtctgctctgagaaacagtgcctttgagagtctt
taccaagataaatttcctttcttcaatcccatccagacccaggtgtttaacactgtatac
aacagtgacgacaacgtgtttgtgggggcccccacgggcagcgggaagactatttgtgca
gagtttgccatcctgcgaatgctgctgcagagctcggaggggcgctgtgtgtacatcacc
cccatggaggccctggcagagcaggtatacatggactggtacgagaagttccaggacagg
ctcaacaagaaggtggtactcctgacaggcgagaccagcacagacctgaagctgctgggc
aaagggaacattatcatcagcacccctgagaagtgggacatactttcccggcgatggaag
cagcgcaagaacgtgcagaacatcaacctcttcgtggtggatgaggtccaccttatcggg
ggcgagaatgggcctgtcttagaagtgatctgctcccgaatgcgctacatctcctcccag
attgagcggcccattcgcattgtggcactcagctcttcgctctccaatgccaaggatgtg
gcccactggctgggctgcagtgccacctccaccttcaacttccatcccaatgtgcgtccc
gtccccttggagctgcacatccagggcttcaacatcagccatacacaaacccgcctgctc
tccatggccaagcctgtgtaccatgctatcaccaagcactcgcccaagaagcctgtcatt
gtctttgtgccgtctcgcaagcagacccgcctcactgccattgacatcctcaccacctgt
gcagcagacatccaacggcagaggttcttgcactgcaccgagaaggatctgattccgtac
ctggagaagctaagtgacagcacgctcaaggaaacgctgctaaatggggtgggctacctg
catgaggggctcagccccatggagcgacgcctggtggagcagctcttcagctcaggggct
atccaggtggtggtggcttctcggagtctctgctggggcatgaacgtggctgcccacctg
gtaatcatcatggatacccagtactacaatggcaagatccacgcctatgtggattacccc
atctatgacgtgcttcagatggtgggccacgccaaccgccctttgcaggacgatgagggg
cgctgtgtcatcatgtgtcagggctccaagaaggatttcttcaagaagttcttatatgag
ccattgccagtagaatctcacctggaccactgtatgcatgaccacttcaatgctgagatc
gtcaccaagaccattgagaacaagcaggatgctgtggactacctcacctggacctttctg
taccgccgcatgacacagaaccccaattactacaacctgcagggcatctcccatcgtcac
ttgtcggaccacttgtcagagctggtggagcagaccctgagtgacctggagcagtccaag
tgcatcagcatcgaggacgagatggacgtggcgcctctgaacctaggcatgatcgccgcc
tactattacatcaactacaccaccattgagctcttcagcatgtccctcaatgccaagacc
aaggtgcgagggcttatcgagatcatctccaatgcagcagagtatgagaacattcccatc
cggcaccatgaagacaatctcctgaggcagttggctcagaaggtcccccacaagctgaat
aaccctaagttcaatgatccgcacgtcaagaccaacctgctcctgcaggctcacttgtct
cgcatgcagctgagtgctgagttgcagtcagatacggaggaaatccttagtaaggcaatc
cggctcatccaggcctgcgtggatgtcctttccagcaatgggtggctcagccctgctctg
gcagctatggaactggcccagatggtcacccaagccatgtggtccaaggactcatacctg
aagcagctgccacacttcacctctgagcatatcaaacgttgcacagacaagggagtggag
agtgttttcgacatcatggagatggaggatgaagaacggaacgcgttgcttcagctgact
gacagccagattgcagatgtggctcgcttttgtaaccgctaccctaatatcgaactatct
tatgaggtggtagataaggacagcatccgcagtggcgggccagttgtggtgctggtgcag
ctggagcgagaggaggaagtcacaggccctgtcattgcgcctctcttcccgcagaaacgt
gaagagggctggtgggtggtgattggagatgccaagtccaatagcctcatctccatcaag
aggctgaccttgcagcagaaggccaaggtgaagttggactttgtggccccagccactggt
gcccacaactacactctgtacttcatgagtgacgcttacatgggatgtgaccaggagtac
aaattcagcgtggatgtgaaagaagctgagacagacagtgattcagattga
DBGET
integrated database retrieval system
