Homo sapiens (human): 2312 Help Entry 2312              CDS       T01001                                  Symbol FLG, ATOD2, FLG-1, FLG1 Name (RefSeq) filaggrin   KO K10384   filaggrin Organism hsa  Homo sapiens (human) Disease H00735   Ichthyosis vulgaris H01358   Atopic dermatitis Brite KEGG Orthology (KO) [BR:hsa00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:hsa04812]     2312 (FLG) Cytoskeleton proteins [BR:hsa04812]  Eukaryotic cytoskeleton proteins   Intermediate filaments    Intermediate filament-binding proteins     2312 (FLG) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Filaggrin S_100 EF-hand_7 EF-hand_1 Motif Other DBs NCBI-GeneID:  2312 NCBI-ProteinID:  NP_002007 OMIM:  135940 HGNC:  3748 Ensembl:  ENSG00000143631 UniProt:  P20930 Structure PDBPDBj LinkDB All DBs Position 1:complement(152302165..152325239) Genome browser AA seq 4061 aa AA seqDB search MSTLLENIFAIINLFKQYSKKDKNTDTLSKKELKELLEKEFRQILKNPDDPDMVDVFMDH LDIDHNKKIDFTEFLLMVFKLAQAYYESTRKENLPISGHKHRKHSHHDKHEDNKQEENKE NRKRPSSLERRNNRKGNKGRSKSPRETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNS SKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQ DEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQD RDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRH AETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGS QASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDS AHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSG HSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRH SQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHP RSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSS RHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESAR DRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDT IRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEE QSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSE RWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAAS SHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEE SDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGR RQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTS QGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGS RTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHG HSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASS AVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRS FLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGR QGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSR HHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYG SAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGER HGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQA GPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDS SRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSG SRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQ DSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTR HTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYS GSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQS ESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDR SGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSS RHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSR HPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADS SRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQEST RGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQD TIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRND EQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDS ERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAA SSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSE DSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTR GRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTT SQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEG SRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGH GHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQAS SAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSG SFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGG RQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVS RHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHR GSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGE RHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQ AGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARD SSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQS GSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVS QDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGT HHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSS GSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQS ESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDR SGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSS RHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSR HPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQS EGTERQKGQSGLVWRHGSYGSADYDYGESGFRHSQHGSVSYNSNPVVFKERSDICKASAF GKDHPRYYATYINKDPGLCGHSSDISKQLGFSQSQRYYYYE NT seq 12186 nt NT seq  +upstreamnt  +downstreamnt atgtctactctcctggaaaacatctttgccataattaatcttttcaagcaatattcaaaa aaagataaaaacactgacacattgagtaaaaaagagctgaaggaacttctggaaaaggaa tttcggcaaatcctgaagaatccagatgacccagatatggttgatgtcttcatggatcac ttggatatagaccacaacaagaaaattgacttcactgagtttcttctgatggtattcaag ttggctcaagcatattatgagtctaccagaaaagagaatttaccgatatcaggacacaag cacagaaagcacagtcatcatgataaacatgaagataataaacaggaagaaaacaaagaa aacagaaaaagaccctcaagtctggaaagaagaaacaatagaaaagggaataagggaaga tccaagagcccaagagaaacaggggggaaaaggcatgaatctagttctgaaaaaaaagaa agaaaaggatattcacctactcatagagaagaagaatatggaaaaaaccatcataactca agtaaaaaagagaaaaacaagactgaaaatactagattaggagacaataggaagaggcta agtgaaagacttgaagagaaagaagacaatgaagaaggagtatatgattatgaaaataca ggaagaatgactcaaaaatggatacaatcaggccatattgccacatattacacaatccag gatgaagcctatgacaccactgatagtctattagaagaaaacaaaatatatgaaagatca aggtcatctgatggcaaatcatcatctcaagtgaacaggtcaagacatgaaaatacaagc caggtaccattgcaggagtccaggacaagaaagcgtaggggatccagagttagccaggac agggacagtgagggacactcagaagactctgagaggcactctgggtcggcttccagaaac catcatggatctgcgtgggagcagtcaagagatggctccagacaccccaggtcccatgat gaagacagagccagtcatgggcactctgcagacagctccagacaatcaggcactcgtcac gcagagacttcctctcgtggacagactgcatcatcccatgaacaggcaagatcaagtcca ggagaaagacatggatccggccaccagcagtcagcagacagctccagacactcagccact gggcgcgggcaagcttcatctgcagtcagcgatcgtggacaccgggggtctagcggtagt caggccagtgacagtgagggacattcagaaaactcagacacacaatcagtgtcaggccac ggaaaggctgggctgagacagcagagccaccaagagtccacacgtggccggtcaggggaa cggtctggacgttcagggtcttccctctaccaggtgagcactcatgaacagcctgactct gcccatggacggaccgggaccagcactggaggaagacaaggatcgcaccacgagcaggca cgagacagctccaggcattcagcgtcccaagagggtcaggacaccattcgtggacacccg gggtcaagcagaggaggaaggcagggatcccaccacgagcaatcggtaaataggtctgga cactcaggttcccatcacagccacaccacatcccagggaaggtctgatgcctcccatggg cagtcaggatccagaagtgcaagcagacaaacacgaaatgaggaacaatcaggagacggc accaggcactcagggtcacgtcatcatgaagcttcctctcaggctgacagctctagacac tcacaggtgggccagggacaatcatcggggcccaggacaagtaggaaccagggatccagt gttagccaggacagtgacagtcagggacactcagaagactctgagaggtggtctgggtct gcttccagaaaccatcatggatctgctcaggagcagtcaagagatggctccagacacccc aggtcccatcacgaagacagagctggtcatgggcactctgcagacagctccagaaaatca ggcactcgtcacacacagaattcctctagtggacaggctgcgtcatcccatgaacaggca agatcaagtgcaggagaaagacatggatcccgccaccagctccagtcagcagacagctcc agacactcaggcactgggcacggacaagcttcatctgcagtcagagacagtggacaccga gggtccagtggtagtcaggccactgacagtgagggacattcagaagactcagacacacag tcagtgtcaggccatggacaggctggtcaccatcagcagagccaccaagagtccgcacgt gaccggtcaggggaaaggtctcgacgttcagggtctttcctctaccaggtgagcactcat aaacagtctgagtcctcccatggatggacagggcccagcactggagtaagacaaggatcc caccatgagcaggcacgagacaactccaggcactcagcatcccaagatggtcaggacacc attcgtggacacccggggtcaagcagaagaggaaggcaggggtcccaccacgagcaatcg gtagataggtctggacactcagggtcccatcacagccacaccacatcccagggaaggtct gatgcctcccgtgggcagtcaggatccagaagtgcaagcagaacaacacgtaatgaggaa caatcaagagacggctccaggcactcagggtcacgtcaccatgaagcttcctctcatgcc gacatctctagacactcacaggcaggccagggacaatcagaggggtccaggacaagcagg cgccagggatccagtgttagccaggacagtgacagtgagggacattcagaagactctgag aggtggtctgggtctgcttccagaaaccatcgtggatctgctcaggagcagtcaagacat ggctccagacaccccaggtcccatcacgaagacagagccggtcacgggcactctgcagac agctccagacaatcaggaactcctcacgcagagacttcctctggtggacaggctgcgtca tcccatgaacaggcaagatcaagtccaggagaaagacacggatcccgccaccagcagtca gcagacagctccagacactcaggcattccgcgcagacaagcttcatctgcagtcagagac agtggacactgggggtccagtggtagtcaggccagtgatagtgagggacattcagaggag tcagacacacagtcagtgtcaggccatggacaggatgggccccatcagcagagccaccaa gagtccgcacgtgactggtcagggggaaggtctggacgttcagggtctttcatctaccag gtgagcactcatgaacagtctgagtctgcccatgggcggaccaggaccagcactggacga agacaaggatcccaccacgagcaggcacgagacagctccaggcactcagcgtcccaagag ggtcaggacaccattcgtgcacacccggggtcaaggagaggaggaaggcagggatcccac catgagcaatcggtagatagatctggacactcagggtcccatcacagccacaccacatcc cagggaaggtctgatgcctcccatgggcagtcaggatccagaagtgcaagcagacaaact cgtaaggacaaacaatcaggagacggctccaggcactcagggtcacgtcaccatgaagct gcctcttgggctgacagctctagacactcacaggtgggacaggaacaatcatcggggtcc aggacaagcaggcaccagggatccagtgttagccaggacagtgacagtgagagacactca gacgactccgagaggttgtctgggtctgcttccagaaaccatcatggatcttctcgggag cagtcaagagatggctccagacaccctgggttccatcaagaagacagagccagtcacggg cactctgcagacagctccagacaatcaggcactcatcacacagagtcttcctctcatgga caggctgtgtcatcccatgaacaggcaagatcaagtccaggagaaagacatggatcccgc caccagcagtcagcagacagctccagacactcaggcattgggcacagacaagcttcatct gcagtcagagacagtggacaccgagggtccagtggtagtcaggtcactaacagtgaggga cattcagaagactcagacacacagtcagtgtcagcccacggacaagctgggccccatcag cagagccacaaagagtccgcacgtggccagtcaggggaaagctctggacgttcaaggtct ttcctctaccaggtgagctctcatgaacagtctgagtccacacacggacagactgcaccc agcactggaggaagacaaggatcccgccatgagcaggcacgaaacagctctaggcactca gcatcccaagacggtcaggacaccattcgtggacacccggggtcaagcagaggaggaagg cagggatcctaccacgagcaatcagtagataggtctggacactcagggtaccatcacagc cacaccacaccccagggaaggtctgatgcctcccatgggcagtcaggacccagaagtgca agcaggcaaacaagaaatgaggaacaatcaggagacggctccaggcactcagggtcacgt caccatgaaccttccactcgggccggcagctctagacactcacaggtgggccagggagaa tcagcggggtccaagacaagcaggcgccagggatccagtgttagtcaggacagggacagt gagggacactcagaagactctgagaggcggtctgagtcggcttccagaaaccattatgga tctgctcgggagcagtcaagacatggctccaggaaccccaggtcccatcaagaagataga gccagtcatgggcactctgcagagagctccagacaatcaggcactcgtcatgcagagact tcctctggtggacaggctgcatcatcccaggaacaggcaaggtcaagtccaggagaaaga catggatcccgccaccagcagtcagcagacagctccacagactcaggcactgggcgcaga caagattcatctgtagtcggagacagtggaaaccgagggtccagtggtagccaggccagt gacagcgagggacactcagaagagtcagacacacagtcagtgtcagcccacggacaggct gggccccatcagcagagccaccaagagtccacacgtggccagtcaggggaaaggtctgga cgttcagggtctttcctctaccaggtgagcactcatgaacagtctgagtccgcccatgga cgcacagggcccagcactggaggaagacaaagatcccgccacgagcaggcacgagacagc tccaggcactcagcgtcccaagagggtcaggacaccattcgtggacacccagggtcaagc agaggaggaaggcagggatcccactatgagcaatcggtagatagttctggacactcaggg tctcatcacagccacaccacgtcccaggaaaggtctgatgtctcccgtgggcagtcagga tccagaagtgtcagcagacaaacacgtaatgagaaacaatcaggagacggctccaggcac tcagggtcgcgtcaccatgaagcttcctctcgggccgacagctctagacactcgcaggtg ggccagggacaatcatcagggcccaggacaagcaggaaccagggatccagtgttagccag gacagtgacagtcagggacactcagaagactctgagaggtggtctgggtctgcttccaga aaccatcttggatctgcttgggagcagtcaagagatggctccagacaccctgggtcccat cacgaagacagagccggtcacgggcactctgcagacagctccagacaatcaggcactcgt cacacagagtcttcctctcgtggacaggctgcgtcatcccatgaacaggcaagatcaagt gcaggagaaagacatggatcccaccaccagctccagtcagcagacagctccagacactca ggcattgggcatggacaagcttcatctgcagtcagagacagtggacaccgagggtacagt ggtagtcaggccagtgacagtgagggacattcagaagactcagacacacagtcagtgtca gcacagggaaaagctgggccccatcagcagagccacaaagagtccgcacgtggccagtca ggggaaagctctggacgttcagggtctttcctctaccaggtgagcactcatgaacagtct gagtccacccatggacagtctgcgcccagcactggaggaagacaaggatcccattatgat caggcacaagacagctccaggcactcagcatcccaagagggtcaggacaccattcgtgga cacccggggccaagcagaggaggaagacaggggtcccaccaagagcaatcggtagatagg tctggacactcagggtctcatcacagccacaccacatcccagggaaggtctgatgcctcc cgtgggcagtcaggatccagaagtgcaagcagaaaaacatatgacaaggaacaatcagga gatggctctaggcactcagggtcgcatcatcatgaagcttcctcttgggccgacagctct agacactcactggtgggccagggacaatcatcagggcccaggacaagcaggccccgggga tccagtgttagccaggacagtgacagtgagggacactcagaagattctgagaggcggtct gggtctgcgtccagaaaccatcatggatctgctcaggagcagtcaagagatggctccaga caccccaggtcccatcacgaagacagagccggtcatgggcactctgcagagagctccaga caatcaggcactcatcatgcagagaattcctctggtggacaggctgcatcatcccatgaa caggcaagatcaagtgcaggagagagacacggatcccaccaccagcagtcagcagacagc tccagacactcaggcattgggcacggacaagcttcatctgcagtcagagacagtggacac cgagggtccagtggtagtcaggccagtgacagtgagggacattcagaagactcagacaca cagtcagtgtcagcccacggacaggctgggccccatcagcagagccaccaagagtccaca cgtggccggtcagcaggaaggtctggacgttcagggtctttcctctaccaggtgagcact catgaacagtctgagtccgcccatggacggaccgggaccagcactggaggaagacaagga tcccaccacaagcaggcacgagacagctccaggcactcaacgtcccaagagggtcaggac accattcatggacacccggggtcaagcagtggaggaaggcagggatcccactacgagcaa ttggtagatagatctggacactcagggtctcatcacagccacaccacatcccagggaagg tctgatgcctcccatgggcactcaggatccagaagtgcaagcagacaaactcgtaacgat gaacaatcaggagacggctccaggcactcagggtcgcgtcaccatgaagcttcctctcgg gccgacagctctggacactcgcaggtgggccagggacaatcagaggggcccaggacaagc aggaactggggatccagttttagccaggacagtgacagtcagggacactcagaagactct gagaggtggtctgggtctgcttccagaaaccatcatggatctgctcaggagcagctaaga gatggctccagacaccccaggtcccatcaagaagacagagctggtcatgggcactctgca gacagctccagacaatcaggcactcgtcacacacagacttcctctggtggacaggctgca tcatcccatgaacaggcaagatcaagtgcaggagaaagacatggatcccaccaccagcag tcagcagacagctccagacactcaggcattgggcacggacaagcttcatctgcagtcaga gacagtggacaccgagggtacagtggtagtcaggccagtgacaatgagggacattcagaa gactcagacacacagtcagtgtcagcccacggacaggctgggtcccatcagcagagccac caagagtccgcacgtggccggtcaggggaaacgtctggacattcaggatctttcctctac caggtgagcactcatgaacagtctgagtcctcccatggatggacggggcccagcactaga ggaagacaaggatcccgccatgagcaggcacaagacagctccaggcactcagcatcccaa gacggtcaggacaccattcgtggacacccggggtcaagcagaggaggaaggcaggggtac caccacgagcattcggtagatagctctggacactcagggtcccatcacagccacaccaca tcccagggaaggtctgatgcctcccgtgggcagtcaggatccagaagtgcaagcagaaca acacgtaatgaggaacaatcaggagacggctccaggcactcagggtcgcgtcaccatgaa gcttccactcatgccgacatctctagacactcacaggcagtccagggacaatcagagggg tccaggagaagcaggcgccagggatccagtgtgagccaggacagtgacagtgagggacat tcagaagactctgagaggtggtctgggtctgcttccagaaaccatcatggatctgctcag gagcagctaagagatggctccagacaccccaggtcccatcaagaagacagagctggtcat gggcactctgcagacagctccagacaatcaggcactcgtcacacacagacttcctctggt ggacaggctgcatcatcccatgaacaggcaagatcaagtgcaggagaaagacatggatcc caccaccagcagtcagcagacagctccagacactcaggcattgggcacggacaagcttca tctgcagtcagagacagtggacaccgagggtacagtggtagtcaggccagtgacaatgag ggacattcagaagactcagacacacagtcagtgtcagcccacggacaggctgggtcccat cagcagagccaccaagagtccgcacgtggccggtcaggggaaacgtctggacattcagga tctttcctctaccaggtgagcactcatgaacagtctgagtcctcccatggatggacgggg cccagcactagaggaagacaaggatcccgccatgagcaggcacaagacagctccaggcac tcagcatcccaatacggtcaggacaccattcgtggacacccggggtcaagcagaggagga aggcaggggtaccaccacgagcattcggtagatagctctggacactcagggtcccatcac agccacaccacatcccagggaaggtctgatgcctcccgtgggcagtcaggatccagaagt gcaagcagaacaacacgtaatgaggaacaatcaggagacagctccaggcactcagtgtca cgtcaccatgaagcttccactcatgccgacatctctagacactcacaggcagtccaggga caatcagaggggtccaggagaagcaggcgccagggatccagtgtgagccaggacagtgac agtgagggacattcagaagactctgagaggtggtctgggtctgcttccagaaaccatcgt ggatctgttcaggagcagtcaaggcacggctccagacaccccaggtcccatcacgaagac agagccggtcacgggcactctgcagaccgctccagacaatcaggcactcgtcacgcagag acttcctctggtggacaggctgcatcatcccatgaacaggcaagatcaagtccaggagag agacacggatcccgccaccagcagtcagcagacagctccagacactcaggcattccgcgt ggacaagcttcatctgcagtcagagacagtagacactgggggtccagtggtagtcaggcc agtgatagtgagggacattcagaagagtcagacacacagtcagtgtcaggccatggacag gctgggccccatcagcagagccaccaagagtccgcacgtgaccggtcagggggaaggtct ggacgttcagggtctttcctctaccaggtgagcactcatgaacagtctgagtctgcccat gggcggaccaggaccagcactggacgaagacaaggatcccaccacgagcaggcacgagac agctccaggcactcagcgtcccaagagggtcaggacaccattcgtggacacccggggtca agcagaagaggaaggcagggatcccactacgagcaatcggtagataggtctggacactca gggtcccatcacagccacaccacatcccagggaaggtctgatgcctcccgtgggcagtca ggatccagaagtgccagcagacaaactcgtaatgacgaacaatcaggagatggctccagg cactcatggtcgcatcaccatgaagcttccactcaggcggacagctctagacactcacag tccggccagggacaatcagcggggcccaggacaagcaggaaccagggatccagtgttagc caggacagtgacagtcagggacactcagaagactctgagaggtggtctgggtctgcttcc agaaaccatcgtggatctgctcaggagcagtcaagagatggctccagacaccccacgtcc catcacgaagacagagccggtcacgggcactctgcagagagctccagacaatcaggcact catcatgcagagaattcctctggtggacaggctgcatcatcccatgaacaggcaagatca agtgcaggagagagacatggatcccaccaccagcagtcagcagacagctccagacactca ggcattgggcacggacaagcttcatctgcagtcagagacagtggacaccgagggtccagt ggtagtcaggccagtgacagtgagggacattcagaagactcagacacacagtcagtgtca gcccacggacaggctgggccccatcagcagagccaccaagagtccacacgtggccggtca gcaggaaggtctggacgttcagggtctttcctctaccaggtgagcactcatgaacagtct gagtctgcccatggacgggctgggcccagtactggaggaagacaaggatcccgccacgag caggcacgagacagctccaggcactcagcgtcccaagagggtcaggacaccattcgtgga cacccggggtcaaggagaggaggaagacagggatcctaccacgagcaatcggtagatagg tctggacactcagggtcccatcacagccacaccacatcccagggaaggtctgatgcctcc catgggcagtcaggatccagaagtgcaagcagagaaacacgtaatgaggaacagtcagga gacggctccaggcactcagggtcgcgtcaccatgaagcttccactcaggctgacagctct agacactcacagtccggccagggtgaatcagcggggtccaggagaagcaggcgccaggga tccagtgttagccaggacagtgacagtgaggcatacccagaggactctgagaggcgatct gagtctgcttccagaaaccatcatggatcttctcgggagcagtcaagagatggctccaga caccccggatcctctcaccgcgatacagccagtcatgtacagtcttcacctgtacagtca gactctagtaccgctaaggaacatggtcactttagtagtctttcacaagattctgcgtat cactcaggaatacagtcacgtggcagtcctcacagttctagttcttatcattatcaatct gagggcactgaaaggcaaaaaggtcaatcaggtttagtttggagacatggcagctatggt agtgcagattatgattatggtgaatccgggtttagacactctcagcacggaagtgttagt tacaattccaatcctgttgttttcaaggaaagatctgatatctgtaaagcaagtgcgttt ggtaaagatcatccaaggtattatgcaacgtatattaataaggacccaggtttatgtggc cattctagtgatatatcgaaacaactgggatttagtcagtcacagagatactattactat gagtaa

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