Homo sapiens (human): 23370
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Entry
23370 CDS
T01001
Symbol
ARHGEF18, P114-RhoGEF, RP78, SA-RhoGEF, p114RhoGEF
Name
(RefSeq) Rho/Rac guanine nucleotide exchange factor 18
KO
K21066
A-kinase anchor protein 18
Organism
hsa
Homo sapiens (human)
Pathway
hsa04530
Tight junction
Disease
H00527
Retinitis pigmentosa
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
23370 (ARHGEF18)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
23370 (ARHGEF18)
Membrane trafficking [BR:
hsa04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
23370 (ARHGEF18)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PH_16
RhoGEF
PH
SOS1_NGEF_PH
VipD-like_C
zf-C2H2_4
Motif
Other DBs
NCBI-GeneID:
23370
NCBI-ProteinID:
NP_001354752
OMIM:
616432
HGNC:
17090
Ensembl:
ENSG00000104880
UniProt:
Q6ZSZ5
LinkDB
All DBs
Position
19:7348937..7479989
Genome browser
AA seq
1361 aa
AA seq
DB search
MGDDQEDDFPRRLSESMEDLSLDLGALQGSEYLQDLGLGAPSHSQPGETPDSRPTGEEPG
RDSLFSSLAGSQDLSRRRSWERSRSCSESWRRLSLDASAVDEEPCLPRTLASLALNLPGG
GLKTWTQGCLSGGGTPAESPGKECDSPKKRGRSRSVPVSFYEIRSPEISPGLEVPTPPVQ
GLEPPVLECMEKDHVEPDHVLIVQQVLQELRQYHGARQRACMSASPGGAHSNLTWFEFLS
ESEDGAGKNEKSDKSTSVKRRLSCLRSRVTRQKEKGKSPAHLKDKGQDARERRECVNGHQ
LLQGTFSGPSSCPLCGKPFLSSASLKEHPRGTLLSDGSPALSRNVGMTVSQKGGPQPTPS
PAGPGTQLGPITGEMDEADSAFLKFKQTADDSLSLTSPNTESIFVEDPYTASLRSEIESD
GHEFEAESWSLAVDAAYAKKQKREVVKRQDVLYELMQTEVHHVRTLKIMLKVYSRALQEE
LQFSSKAIGRLFPCADDLLETHSHFLARLKERRQESLEEGSDRNYVIQKIGDLLVQQFSG
ENGERMKEKYGVFCSGHNEAVSHYKLLLQQNKKFQNLIKKIGNFSIVRRLGVQECILLVT
QRITKYPVLVERIIQNTEAGTEDYEDLTQALNLIKDIISQVDAKVSECEKGQRLREIAGK
MDLKSSSKLKNGLTFRKEDMLQRQLHLEGMLCWKTTSGRLKDILAILLTDVLLLLQEKDQ
KYVFASVDSKPPVISLQKLIVREVANEEKAMFLISASLQGPEMYEIYTSSKEDRNAWMAH
IQRAVESCPDEEEGPFSLPEEERKVVEARATRLRDFQERLSMKDQLIAQSLLEKQQIYLE
MAEMGGLEDLPQPRGLFRGGDPSETLQGELILKSAMSEIEGIQSLICRQLGSANGQAEDG
GSSTGPPRRAETFAGYDCTNSPTKNGSFKKKVSSTDPRPRDWRGPPNSPDLKLSDSDIPG
SSEESPQVVEAPGTESDPRLPTVLESELVQRIQTLSQLLLNLQAVIAHQDSYVETQRAAI
QEREKQFRLQSTRGNLLLEQERQRNFEKQREERAALEKLQSQLRHEQQRWERERQWQHQE
LERAGARLQEREGEARQLRERLEQERAELERQRQAYQHDLERLREAQRAVERERERLELL
RRLKKQNTAPGALPPDTLAEAQPPSHPPSFNGEGLEGPRVSMLPSGVGPEYAERPEVARR
DSAPTENRLAKSDVPIQLLSATNQFQRQAAVQQQIPTKLAASTKGGKDKGGKSRGSQRWE
SSASFDLKQQLLLNKLMGKDESTSRNRRSLSPILPGRHSPAPPPDPGFPAPSPPPADSPS
EGFSLKAGGTALLPGPPAPSPLPATPLSAKEDASKEDVIFF
NT seq
4086 nt
NT seq
+upstream
nt +downstream
nt
atgggggatgatcaggaggatgattttcccaggcggctcagcgagagtatggaggacctc
agcctggatttgggggcccttcagggcagcgagtatctgcaggacctgggccttggggcc
ccttcccacagccagcctggggagaccccagacagccgccccaccggtgaagaaccagga
agagattctcttttctccagcttggcagggtcccaagacctgtcaaggcggcgcagctgg
gaaaggtcgcggagctgctcagagagctggcggaggctcagcctcgatgcctcagctgtg
gatgaggaaccctgtctcccccgaacactggccagccttgctttgaacctgccaggagga
gggctgaagacctggactcaagggtgtctctctgggggcgggacccccgcagagagccca
ggcaaggaatgtgacagccccaagaaaagagggaggtcaaggtccgttcctgtgtccttc
tatgagatccgctctccggaaatctctccgggtttggaagtgcccactccacctgttcaa
ggcctggaacctccagtgctggagtgcatggaaaaagaccatgtggaaccagatcacgtg
ctgattgtccagcaggtgcttcaagaacttcgacagtaccatggggcccggcagagggct
tgcatgtcagccagccccggaggagcccactcgaacctgacctggtttgaattcctgtcg
gagagcgaggacggtgctggcaagaacgagaagagtgacaagagtaccagtgtgaagcgc
aggctgagctgcctccgcagtcgagtgaccaggcagaaggagaaggggaagagcccagca
catctgaaggacaagggccaggatgcacgagagaggcgggagtgtgtcaatgggcaccag
ctgttgcaagggaccttctccggcccctccagctgccccctgtgtggcaaacctttcttg
agctcagcctcgctcaaggagcacccccggggcaccctcctgtccgatggcagcccggcc
ctgtccaggaatgtcggtatgacggtctctcagaaagggggtccccagccaacaccgagc
ccggctggccctgggacgcaactcggaccaatcacaggagagatggatgaagccgattct
gcgtttttaaaatttaagcagacagctgatgactctctgtcccttacatctccaaacacc
gagtccatttttgtagaagatccctacaccgcctcgctgaggagtgagattgagtcagac
ggccacgagtttgaagctgagtcctggagcctcgccgtggatgcagcctacgccaagaag
caaaagagggaggtggtgaaaagacaagatgtcctttatgagctgatgcagacagaggtg
caccacgtgcggacgctcaagatcatgctgaaggtgtactccagggccctgcaggaggag
ctgcagttcagcagcaaggccattggccgcctcttcccatgcgctgacgacctgctggag
acgcacagccacttcctcgctcggctcaaggagcgccgccaggagtccctggaggagggc
agtgaccggaattatgtcatccagaaaatcggcgacctcctggttcagcagttttcaggt
gaaaatggggagagaatgaaagaaaagtacggtgtgttttgtagtggccacaatgaagct
gttagtcattacaagttgctgcttcagcaaaacaagaaatttcaaaacttgatcaagaaa
attggcaacttctccatcgtgcggcggcttggcgtgcaggagtgcattctcctggttaca
caacgcataaccaaatacccagtgctggtggagcgcatcatccagaacacggaagctggc
actgaggactatgaagacctgacccaggccttgaacctcatcaaagatatcatctcacaa
gtggacgccaaggtcagtgagtgtgagaagggccagcgcctcagggagatcgcagggaag
atggacctgaagtcttccagcaaactcaagaacgggctcaccttccgcaaggaagacatg
cttcagcggcagctccacctggagggcatgctatgctggaagaccacatcagggcgcttg
aaagatatcctggctatcctgctgaccgacgtacttttgctgctacaagaaaaagatcag
aaatacgtctttgcttctgtggactcaaagccacccgtcatctcgttacaaaagctcatc
gtgagggaagtggccaacgaggagaaagcgatgtttctgatcagcgcctccttgcaaggg
ccggagatgtatgaaatctacacgagctccaaagaggacaggaacgcctggatggcccac
atccaaagggctgtggagagctgccctgacgaggaggaggggcccttcagcctgcccgaa
gaggaaaggaaggtggtcgaggcccgcgccacgagactccgggactttcaagagcggttg
agcatgaaagaccagctgatcgcacagagcctcctagagaaacagcagatctacctggag
atggccgagatgggcggcctcgaagacctgccccagccccgaggcctattccgtggaggg
gacccatccgagaccctgcagggggagctaattctcaagtcggccatgagcgagatcgag
ggcatccagagcctgatctgcaggcagctgggcagcgccaacggccaggcggaagacgga
ggcagctccacaggcccgcccaggagggctgagaccttcgcgggctacgactgcacaaac
agccccaccaagaatggcagtttcaagaagaaagtcagcagcactgaccccaggccccga
gactggcgaggccccccaaacagcccggacttgaagctcagtgacagtgacattcctggg
agctctgaggaatcgccgcaggtggtggaggcgccaggcacggaatccgatccccgtctg
cccaccgtcctggagtcggagcttgtccagcggatccagacactgtcccagctgctcctg
aaccttcaggcggtaatcgcccaccaggacagctatgtggagacgcagcgggctgccatc
caggagcgggagaagcagttccggctgcagtcgacgcgtgggaacctgctgctggagcag
gagcggcaacgcaacttcgagaagcagcgggaggagcgcgcggccctggagaagctgcag
agccagctgcggcacgagcagcagcgctgggagcgcgagcgccagtggcagcaccaggag
ctggagcgtgcgggcgcgcggctgcaggagcgcgagggcgaggcgcggcagctacgcgag
cggctggagcaggagcgggccgagctggagcgccagcgccaggcctaccagcacgacctg
gagcggctgcgcgaggcccagcgtgccgtggagcgcgagcgggagcgcctggagctgctg
cgccgcctcaagaagcagaacaccgcgccaggcgcgctgccgcccgacacactggccgag
gcccagcccccaagccaccctcccagcttcaacggggaagggctggagggccctcgtgtg
agcatgctgccatccggcgtggggccagagtacgcagagcgccccgaggtggctcgccgg
gacagcgcccccaccgagaaccggctggccaagagcgatgtgcccatccagctgctcagc
gccaccaaccagttccagaggcaggcggccgtgcagcagcagatccccaccaagctggcg
gcctccaccaagggtggcaaggacaagggcggcaagagcaggggctctcagcgctgggag
agctcagcgtccttcgacctgaagcagcagctgctgctcaacaagctcatggggaaagat
gagagcacctcacggaaccgccgctcgctgagccctatcctgcccggcagacacagtcct
gcgcccccaccagaccctggcttccccgccccgagcccaccgccagctgacagcccctcc
gagggcttctctctcaaggccgggggcacagccctcctgcccgggcccccagctccctcg
ccactgccggccacaccactcagcgccaaggaggacgccagcaaagaagacgtcatcttc
ttctaa
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integrated database retrieval system
