Homo sapiens (human): 23451
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Entry
23451 CDS
T01001
Symbol
SF3B1, Hsh155, MDS, PRP10, PRPF10, SAP155, SF3b155
Name
(RefSeq) splicing factor 3b subunit 1
KO
K12828
splicing factor 3B subunit 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa03040
Spliceosome
Disease
H01481
Myelodysplastic syndrome
H02410
Myelodysplastic/myeloproliferative neoplasms
H02411
Chronic myelomonocytic leukemia
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09121 Transcription
03040 Spliceosome
23451 (SF3B1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03041 Spliceosome [BR:
hsa03041
]
23451 (SF3B1)
03036 Chromosome and associated proteins [BR:
hsa03036
]
23451 (SF3B1)
Spliceosome [BR:
hsa03041
]
Complex A
U2 snRNP components
U2 snRNP specific factors
23451 (SF3B1)
Complex B
23451 (SF3B1)
Complex C
U2 SnRNP specific factors
23451 (SF3B1)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Chromatin remodeling factors
B-WICH complex
23451 (SF3B1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SF3b1
PPP2R1A-like_HEAT
TOR1L1_N
HEAT_EZ
HEAT_EF3_N
HEAT_ECM29
Htt_N-HEAT_1
HEAT_2
XMAP215_CLASP_TOG
Adaptin_N
UNC45-central
DUF2298
TALPID3
Motif
Other DBs
NCBI-GeneID:
23451
NCBI-ProteinID:
NP_036565
OMIM:
605590
HGNC:
10768
Ensembl:
ENSG00000115524
UniProt:
O75533
B4DGZ4
Structure
PDB
PDBj
LinkDB
All DBs
Position
2:complement(197389784..197435093)
Genome browser
AA seq
1304 aa
AA seq
DB search
MAKIAKTHEDIEAQIREIQGKKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAA
TELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYK
KHRRTMIISPERLDPFADGGKTPDPKMNARTYMDVMREQHLTKEEREIRQQLAEKAKAGE
LKVVNGAAASQPPSKRKRRWDQTADQTPGATPKKLSSWDQAETPGHTPSLRWDETPGRAK
GSETPGATPGSKIWDPTPSHTPAGAATPGRGDTPGHATPGHGGATSSARKNRWDETPKTE
RDTPGHGSGWAETPRTDRGGDSIGETPTPGASKRKSRWDETPASQMGGSTPVLTPGKTPI
GTPAMNMATPTPGHIMSMTPEQLQAWRWEREIDERNRPLSDEELDAMFPEGYKVLPPPAG
YVPIRTPARKLTATPTPLGGMTGFHMQTEDRTMKSVNDQPSGNLPFLKPDDIQYFDKLLV
DVDESTLSPEEQKERKIMKLLLKIKNGTPPMRKAALRQITDKAREFGAGPLFNQILPLLM
SPTLEDQERHLLVKVIDRILYKLDDLVRPYVHKILVVIEPLLIDEDYYARVEGREIISNL
AKAAGLATMISTMRPDIDNMDEYVRNTTARAFAVVASALGIPSLLPFLKAVCKSKKSWQA
RHTGIKIVQQIAILMGCAILPHLRSLVEIIEHGLVDEQQKVRTISALAIAALAEAATPYG
IESFDSVLKPLWKGIRQHRGKGLAAFLKAIGYLIPLMDAEYANYYTREVMLILIREFQSP
DEEMKKIVLKVVKQCCGTDGVEANYIKTEILPPFFKHFWQHRMALDRRNYRQLVDTTVEL
ANKVGAAEIISRIVDDLKDEAEQYRKMVMETIEKIMGNLGAADIDHKLEEQLIDGILYAF
QEQTTEDSVMLNGFGTVVNALGKRVKPYLPQICGTVLWRLNNKSAKVRQQAADLISRTAV
VMKTCQEEKLMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIGMHKMTPPIKDLLPRL
TPILKNRHEKVQENCIDLVGRIADRGAEYVSAREWMRICFELLELLKAHKKAIRRATVNT
FGYIAKAIGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPALMNEYRVPE
LNVQNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMSLGVY
GFGCEDSLNHLLNYVWPNVFETSPHVIQAVMGALEGLRVAIGPCRMLQYCLQGLFHPARK
VRDVYWKIYNSIYIGSQDALIAHYPRIYNDDKNTYIRYELDYIL
NT seq
3915 nt
NT seq
+upstream
nt +downstream
nt
atggcgaagatcgccaagactcacgaagatattgaagcacagattcgagaaattcaaggc
aagaaggcagctcttgatgaagctcaaggagtgggcctcgattctacaggttattatgac
caggaaatttatggtggaagtgacagcagatttgctggatacgtgacatcaattgctgca
actgaacttgaagatgatgacgatgactattcatcatctacgagtttgcttggtcagaag
aagccaggatatcatgcccctgtggcattgcttaatgatataccacagtcaacagaacag
tatgatccatttgctgagcacagacctccaaagattgcagaccgggaagatgaatacaaa
aagcataggcggaccatgataatttccccagagcgtcttgatccttttgcagatggaggg
aaaacccctgatcctaaaatgaatgctaggacttacatggatgtaatgcgagaacaacac
ttgactaaagaagaacgagaaattaggcaacagctagcagaaaaagctaaagctggagaa
ctaaaagtcgtcaatggagcagcagcgtcccagcctccatcaaaacgaaaacggcgttgg
gatcaaacagctgatcagactcctggtgccactcccaaaaaactatcaagttgggatcag
gcagagacccctgggcatactccttccttaagatgggatgagacaccaggtcgtgcaaag
ggaagcgagactcctggagcaaccccaggctcaaaaatatgggatcctacacctagccac
acaccagcgggagctgctactcctggacgaggtgatacaccaggccatgcgacaccaggc
catggaggcgcaacttccagtgctcgtaaaaacagatgggatgaaacccccaaaacagag
agagatactcctgggcatggaagtggatgggctgagactcctcgaacagatcgaggtgga
gattctattggtgaaacaccgactcctggagccagtaaaagaaaatcacggtgggatgaa
acaccagctagtcagatgggtggaagcactccagttctgacccctggaaagacaccaatt
ggcacaccagccatgaacatggctacccctactccaggtcacataatgagtatgactcct
gaacagcttcaggcttggcggtgggaaagagaaattgatgagagaaatcgcccactttct
gatgaggaattagatgctatgttcccagaaggatataaggtacttcctcctccagctggt
tatgttcctattcgaactccagctcgaaagctgacagctactccaacacctttgggtggt
atgactggtttccacatgcaaactgaagatcgaactatgaaaagtgttaatgaccagcca
tctggaaatcttccatttttaaaacctgatgatattcaatactttgataaactattggtt
gatgttgatgaatcaacacttagtccagaagagcaaaaagagagaaaaataatgaagttg
cttttaaaaattaagaatggaacaccaccaatgagaaaggctgcattgcgtcagattact
gataaagctcgtgaatttggagctggtcctttgtttaatcagattcttcctctgctgatg
tctcctacacttgaggatcaagagcgtcatttacttgtgaaagttattgataggatactg
tacaaacttgatgacttagttcgtccatatgtgcataagatcctcgtggtcattgaaccg
ctattgattgatgaagattactatgctagagtggaaggccgagagatcatttctaatttg
gcaaaggctgctggtctggctactatgatctctaccatgagacctgatatagataacatg
gatgagtatgtccgtaacacaacagctagagcttttgctgttgtagcctctgccctgggc
attccttctttattgcccttcttaaaagctgtgtgcaaaagcaagaagtcctggcaagcg
agacacactggtattaagattgtacaacagatagctattcttatgggctgtgccatcttg
ccacatcttagaagtttagttgaaatcattgaacatggtcttgtggatgagcagcagaaa
gttcggaccatcagtgctttggccattgctgccttggctgaagcagcaactccttatggt
atcgaatcttttgattctgtgttaaagcctttatggaagggtatccgccaacacagagga
aagggtttggctgctttcttgaaggctattgggtatcttattcctcttatggatgcagaa
tatgccaactactatactagagaagtgatgttaatccttattcgagaattccagtctcct
gatgaggaaatgaaaaaaattgtgctgaaggtggtaaaacagtgttgtgggacagatggt
gtagaagcaaactacattaaaacagagattcttcctcccttttttaaacacttctggcag
cacaggatggctttggatagaagaaattaccgacagttagttgatactactgtggagttg
gcaaacaaagtaggtgcagcagaaattatatccaggattgtggatgatctgaaagatgaa
gccgaacagtacagaaaaatggtgatggagacaattgagaaaattatgggtaatttggga
gcagcagatattgatcataaacttgaagaacaactgattgatggtattctttatgctttc
caagaacagactacagaggactcagtaatgttgaacggctttggcacagtggttaatgct
cttggcaaacgagtcaaaccatacttgcctcagatctgtggtacagttttgtggcgttta
aataacaaatctgctaaagttaggcaacaggcagctgacttgatttctcgaactgctgtt
gtcatgaagacttgtcaagaggaaaaattgatgggacacttgggtgttgtattgtatgag
tatttgggtgaagagtaccctgaagtattgggcagcattcttggagcactgaaggccatt
gtaaatgtcataggtatgcataagatgactccaccaattaaagatctgctgcctagactc
acccccatcttaaagaacagacatgaaaaagtacaagagaattgtattgatcttgttggt
cgtattgctgacaggggagctgaatatgtatctgcaagagagtggatgaggatttgcttt
gagcttttagagctcttaaaagcccacaaaaaggctattcgtagagccacagtcaacaca
tttggttatattgcaaaggccattggccctcatgatgtattggctacacttctgaacaac
ctcaaagttcaagaaaggcagaacagagtttgtaccactgtagcaatagctattgttgca
gaaacatgttcaccctttacagtactccctgccttaatgaatgaatacagagttcctgaa
ctgaatgttcaaaatggagtgttaaaatcgctttccttcttgtttgaatatattggtgaa
atgggaaaagactacatttatgccgtaacaccgttacttgaagatgctttaatggataga
gaccttgtacacagacagacggctagtgcagtggtacagcacatgtcacttggggtttat
ggatttggttgtgaagattcgctgaatcacttgttgaactatgtatggcccaatgtattt
gagacatctcctcatgtaattcaggcagttatgggagccctagagggcctgagagttgct
attggaccatgtagaatgttgcaatattgtttacagggtctgtttcacccagcccggaaa
gtcagagatgtatattggaaaatttacaactccatctacattggttcccaggacgctctc
atagcacattacccaagaatctacaacgatgataagaacacctatattcgttatgaactt
gactatatcttataa
DBGET
integrated database retrieval system
