Homo sapiens (human): 23511 Help Entry 23511             CDS       T01001                                  Symbol NUP188, KIAA0169, SANDSTEF, hNup188 Name (RefSeq) nucleoporin 188   KO K14311   nuclear pore complex protein Nup188 Organism hsa  Homo sapiens (human) Pathway hsa03013   Nucleocytoplasmic transport hsa05014   Amyotrophic lateral sclerosis Network nt06464  Amyotrophic lateral sclerosis   Element N01152   Nuclear export of mRNA N01153   Mutation-caused aberrant GLE1 to nuclear export of mRNA Disease H02821   Sandestig-Stefanova syndrome Brite KEGG Orthology (KO) [BR:hsa00001]  09120 Genetic Information Processing   09122 Translation    03013 Nucleocytoplasmic transport     23511 (NUP188)  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     23511 (NUP188)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03019 Messenger RNA biogenesis [BR:hsa03019]     23511 (NUP188) Messenger RNA biogenesis [BR:hsa03019]  Eukaryotic type   mRNA surveillance and transport factors    Transport factors     Nuclear pore complex      23511 (NUP188) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Nup188_N-subdom_III Nup188_N Nup188_SH3-like HEAT_SCC3-SA TRS130_4HB Gar1 Motif Other DBs NCBI-GeneID:  23511 NCBI-ProteinID:  NP_056169 OMIM:  615587 HGNC:  17859 Ensembl:  ENSG00000095319 UniProt:  Q5SRE5 Structure PDBPDBj LinkDB All DBs Position 9:128947699..129007096 Genome browser AA seq 1749 aa AA seqDB search MAAAAGGPCVRSSRELWTILLGRSALRELSQIEAELNKHWRRLLEGLSYYKPPSPSSAEK VKANKDVASPLKELGLRISKFLGLDEEQSVQLLQCYLQEDYRGTRDSVKTVLQDERQSQA LILKIADYYYEERTCILRCVLHLLTYFQDERHPYRVEYADCVDKLEKELVSKYRQQFEEL YKTEAPTWETHGNLMTERQVSRWFVQCLREQSMLLEIIFLYYAYFEMAPSDLLVLTKMFK EQGFGSRQTNRHLVDETMDPFVDRIGYFSALILVEGMDIESLHKCALDDRRELHQFAQDG LICQDMDCLMLTFGDIPHHAPVLLAWALLRHTLNPEETSSVVRKIGGTAIQLNVFQYLTR LLQSLASGGNDCTTSTACMCVYGLLSFVLTSLELHTLGNQQDIIDTACEVLADPSLPELF WGTEPTSGLGIILDSVCGMFPHLLSPLLQLLRALVSGKSTAKKVYSFLDKMSFYNELYKH KPHDVISHEDGTLWRRQTPKLLYPLGGQTNLRIPQGTVGQVMLDDRAYLVRWEYSYSSWT LFTCEIEMLLHVVSTADVIQHCQRVKPIIDLVHKVISTDLSIADCLLPITSRIYMLLQRL TTVISPPVDVIASCVNCLTVLAARNPAKVWTDLRHTGFLPFVAHPVSSLSQMISAEGMNA GGYGNLLMNSEQPQGEYGVTIAFLRLITTLVKGQLGSTQSQGLVPCVMFVLKEMLPSYHK WRYNSHGVREQIGCLILELIHAILNLCHETDLHSSHTPSLQFLCICSLAYTEAGQTVINI MGIGVDTIDMVMAAQPRSDGAEGQGQGQLLIKTVKLAFSVTNNVIRLKPPSNVVSPLEQA LSQHGAHGNNLIAVLAKYIYHKHDPALPRLAIQLLKRLATVAPMSVYACLGNDAAAIRDA FLTRLQSKIEDMRIKVMILEFLTVAVETQPGLIELFLNLEVKDGSDGSKEFSLGMWSCLH AVLELIDSQQQDRYWCPPLLHRAAIAFLHALWQDRRDSAMLVLRTKPKFWENLTSPLFGT LSPPSETSEPSILETCALIMKIICLEIYYVVKGSLDQSLKDTLKKFSIEKRFAYWSGYVK SLAVHVAETEGSSCTSLLEYQMLVSAWRMLLIIATTHADIMHLTDSVVRRQLFLDVLDGT KALLLVPASVNCLRLGSMKCTLLLILLRQWKRELGSVDEILGPLTEILEGVLQADQQLME KTKAKVFSAFITVLQMKEMKVSDIPQYSQLVLNVCETLQEEVIALFDQTRHSLALGSATE DKDSMETDDCSRSRHRDQRDGVCVLGLHLAKELCEVDEDGDSWLQVTRRLPILPTLLTTL EVSLRMKQNLHFTEATLHLLLTLARTQQGATAVAGAGITQSICLPLLSVYQLSTNGTAQT PSASRKSLDAPSWPGVYRLSMSLMEQLLKTLRYNFLPEALDFVGVHQERTLQCLNAVRTV QSLACLEEADHTVGFILQLSNFMKEWHFHLPQLMRDIQVNLGYLCQACTSLLHSRKMLQH YLQNKNGDGLPSAVAQRVQRPPSAASAAPSSSKQPAADTEASEQQALHTVQYGLLKILSK TLAALRHFTPDVCQILLDQSLDLAEYNFLFALSFTTPTFDSEVAPSFGTLLATVNVALNM LGELDKKKEPLTQAVGLSTQAEGTRTLKSLLMFTMENCFYLLISQAMRYLRDPAVHPRDK QRMKQELSSELSTLLSSLSRYFRRGAPSSPATGVLPSPQGKSTSLSKASPESQEPLIQLV QAFVRHMQR NT seq 5250 nt NT seq  +upstreamnt  +downstreamnt atggcggcggccgccggcgggccgtgtgtgaggagcagtagagaactgtggactattctg cttggaaggtcagctctgagagagctgagtcagattgaggcagaactgaataaacattgg cggcgattgttagaggggctttcttactacaaacctcccagtccaagttcagctgaaaaa gtgaaagctaataaagatgtagcttcaccattgaaggaactgggtttaagaatcagcaag tttttgggtcttgatgaagaacagagtgtgcagttactccagtgttacctgcaagaggac tacaggggtactcgggactcagtaaagacagtactgcaagatgagaggcagagccaggcc ttaatcctgaagattgcagattattattatgaagaaagaacctgtattcttcgttgtgtc ttacaccttctcacttacttccaagatgaaagacacccctatagggttgaatatgcagac tgtgttgataaattggagaaggaactagtttcaaaatacagacagcagttcgaagagctt tataaaactgaagcaccaacttgggagacacatggaaatctcatgacagagcgccaagtg tctcgctggtttgttcagtgccttcgggaacagtccatgctgctagaaattattttcctt tattatgcatactttgagatggcacccagtgacttacttgtattaaccaagatgtttaaa gagcaaggatttggtagtaggcagaccaataggcacctggtggatgagactatggatcct tttgtagatcggattggctacttcagtgccctcatcctggtggagggcatggatatcgag tccttgcataagtgtgctttggatgacagaagagaactgcatcagtttgcgcaggatggg cttatttgtcaggatatggactgtttaatgttgacctttggggacattccacatcatgcc ccagtgcttttggcctgggctctcctccgtcacactctgaacccagaagagacaagcagt gtggtccggaagataggtggcacagccatccagctgaatgtgtttcagtacttgacccga ttgctccagtcccttgccagtgggggaaatgattgcaccaccagcactgcatgcatgtgt gtctatggactgctctctttcgttctgacctcgttggagctgcacaccctgggcaatcag caggatataattgatacagcatgtgaagtattggccgacccttctcttccggaactgttc tggggaacagagccaacttctggccttgggatcattctggacagtgtgtgtggaatgttt ccccaccttctctccccactcctgcaactgctccgagccctggtatcagggaagtccaca gccaaaaaggtgtatagcttcttggataagatgtctttctacaatgaactttataaacac aagcctcatgatgtgatctcccatgaagatggaactctttggcggagacaaacacccaaa ctcctttatccccttgggggtcaaaccaaccttcgcatacctcaaggcactgtgggccaa gtaatgttggatgatagggcatacctggtacgctgggaatactcctatagcagctggacc ctctttacctgcgagattgaaatgttgcttcatgttgtttcaactgcagatgtgattcag cactgccagcgagtcaaacccatcattgatctcgtccataaggtcatcagtacagacctg tcgatagcagactgtctcctgcccatcacatctcgcatctacatgctgctgcagcggtta acgacagtgatctccccacctgtggatgtcattgcttcttgtgtcaactgcttaactgtt ttggctgcccgcaatccagcaaaggtctggactgatcttcgtcacacaggttttttacca tttgtggcccatcctgtctccagcctgagtcagatgattagtgcggaagggatgaatgct ggagggtacggaaacctcttgatgaacagtgaacagcctcagggcgagtatggggttact attgcctttctgcgcttgatcaccacccttgtcaaggggcaacttggtagtacccagagc caaggacttgtaccctgtgtaatgtttgtgctgaaggagatgcttcccagctaccataag tggcgctacaactctcatggagtgagggaacagattggttgcctgatcttggagctgatt catgcgatactgaacctgtgccacgagacagacctgcacagcagtcatactcccagcctg cagtttctctgcatctgcagcctggcatacacagaagcaggacagacagttatcaatatc atgggcattggcgtggacaccattgacatggtgatggctgctcagcctcgaagtgatggg gcagagggccaggggcagggccagctgctgatcaagacagtgaaactggcattctccgtc accaacaatgttattcggctgaaacctccttctaatgtggtgtcccccctggaacaggct ctctcacaacatggtgctcatggaaacaacctcattgctgttctagccaaatacatctac cacaaacatgaccctgctttgccacgtcttgccattcagctgctgaaacgtctggccacg gtggccccaatgtcagtgtatgcttgtctgggcaatgatgcggctgccattcgtgatgcc ttcctgacccgattgcagagcaaaattgaggacatgcgcatcaaagtcatgattctagag ttcctcactgttgcagtagagacccagccaggcctcatcgaactgtttctgaacctggaa gttaaggatggcagtgatggctcaaaggaattcagccttgggatgtggagctgtctccat gcagtgctggagctgattgattcccaacagcaagatcgatactggtgcccacccctgctg catcgtgccgccattgcctttttgcatgctctgtggcaggatcggagggacagtgccatg ctggtcctccgaaccaaacccaagttttgggaaaatttaaccagtccgctgtttggaacc ctttctcctccctctgaaacatcagagcccagcatcctggaaacctgtgccctaatcatg aagataatttgcttggagatatactatgtagtaaagggttcattagaccagtcattaaag gatacactgaagaaattttccatcgagaaacgctttgcctactggtcagggtatgtcaag tcattggcagttcacgtggccgaaacagaaggcagcagctgcacctccttgttagagtac cagatgctggtgtccgcctggaggatgcttctcatcattgccaccactcatgcagatata atgcacctgactgactctgtggtgcgtcgccagctctttcttgacgtgcttgatggaacc aaagcattactcctagttccagcctcagtgaactgccttcgccttggctccatgaagtgc actctgctgcttatcctcctccggcagtggaagagagagttaggttctgtggatgaaatc cttggacccttgacggagatcctggagggagtgctgcaggccgaccagcaactcatggag aagaccaaggccaaggtgttctcagcattcatcacagtgttgcaaatgaaggagatgaaa gtaagtgacatcccccagtactcccagctggtgctgaatgtctgtgagaccctccaagag gaagtgattgcactcttcgaccagacccgccacagtctggcattaggcagtgccacagag gacaaggacagcatggagactgacgactgttctcggtcccggcacagggaccagcgtgat ggggtgtgtgtcctgggcctgcacctggccaaggagctgtgtgaggtagacgaggatggt gactcctggctgcaggtaacccgcaggctccccatcctacccaccctcctcaccactcta gaggtgagccttcgcatgaagcagaacctgcatttcactgaggccacattgcatctgctc ctcaccctggctcgcactcagcagggagccacagcagtggctggagctggcatcacccag agcatttgtttgccccttctgagtgtgtaccagctgagcaccaacggcacagcacagaca cctagtgcctctcggaagtccctggatgccccctcttggccaggagtctaccgcctgtcc atgtccctgatggagcagctgctcaaaactctgcgctacaacttcctgcctgaggccctg gacttcgtgggtgtccaccaggagcggaccttacagtgcctcaacgcagtgaggacagtg cagagtctggcctgcctggaggaggcggaccacaccgtgggttttattctgcagctctct aacttcatgaaggagtggcacttccacctgcctcagctcatgcgtgatatccaggtcaac ctgggttacttgtgccaggcatgtacctctctcctgcacagtcgaaagatgctgcagcat tacttacagaacaaaaatggggatggcctcccctcagctgttgcccagcgagtccagagg ccaccgtctgctgcttctgctgccccctcctcctcaaagcagcccgctgctgacacagag gcatcagagcagcaggccttgcacacagtccagtatggccttctcaagatcctcagcaag acgctggcagccctgcgccacttcaccccagatgtctgccagattctgctggatcagtcc ctggaccttgctgaatacaacttcctgtttgccctgagctttaccactcccacctttgac tccgaagtggccccctccttcgggacccttctggccacagtgaatgtggccctcaacatg cttggagagctggacaagaaaaaggagcccctcacccaggcagtggggctcagcacacag gcagaagggaccaggacgttaaagtccctcctgatgtttaccatggaaaactgcttctac ctgctcatctctcaggcgatgcggtaccttagggacccggctgtgcacccccgggacaaa cagcggatgaagcaggagctcagctctgagttgagcacgctgctgtccagcctctcgcgc tacttccgccggggagcccccagctcccctgccactggtgtcctcccctcgccgcagggc aagtccacctctctctccaaagccagccctgagagtcaggagcctctgatccagttggtg caggcgtttgtccggcatatgcaaagatag

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