KEGG   Homo sapiens (human): 246721
Entry
246721            CDS       T01001                                 
Symbol
POLR2J2, HRPB11B, RPB11b1
Name
(RefSeq) RNA polymerase II subunit J2
  KO
K03008  DNA-directed RNA polymerase II subunit RPB11
Organism
hsa  Homo sapiens (human)
Pathway
hsa03020  RNA polymerase
hsa03420  Nucleotide excision repair
hsa05016  Huntington disease
Network
nt06502  Nucleotide excision repair
  Element
N01430  Transcription-coupled NER
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03020 RNA polymerase
    246721 (POLR2J2)
  09124 Replication and repair
   03420 Nucleotide excision repair
    246721 (POLR2J2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    246721 (POLR2J2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    246721 (POLR2J2)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    246721 (POLR2J2)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   RNA polymerase II
    Core subunits
     246721 (POLR2J2)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    TCR (transcription coupled repair) factors
     DNA-directed RNA polymerase II complex
      246721 (POLR2J2)
SSDB
Motif
Pfam: RNA_pol_L_2 RNA_pol_L
Other DBs
NCBI-GeneID: 246721
NCBI-ProteinID: NP_116581
OMIM: 609881
HGNC: 23208
Ensembl: ENSG00000228049
UniProt: Q9GZM3
LinkDB
Position
7:complement(102666046..102671663)
AA seq 115 aa
MNAPPAFESFLLFEGEKITINKDTKVPKACLFTINKEDHTLGNIIKSQLLKDPQVLFAGY
KVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLISELSLLEERFRTCLLPLRLLP
NT seq 348 nt   +upstreamnt  +downstreamnt
atgaacgcccctccagccttcgagtcgttcttgctcttcgagggcgagaagatcaccatt
aacaaggacaccaaggtacccaaggcctgcttattcaccatcaacaaagaagaccacaca
ctgggaaacatcattaaatcacaactcctaaaagacccgcaagtgctatttgctggctac
aaagtcccccaccccttggagcacaagatcatcatccgagtgcagaccacgccggactac
agcccccaggaagcctttaccaacgccatcaccgacctcatcagtgagctgtccctgctg
gaggagcgcttccggacgtgcctgcttccccttcgccttctgccgtga

KEGG   Homo sapiens (human): 5430
Entry
5430              CDS       T01001                                 
Symbol
POLR2A, NEDHIB, POLR2, POLRA, RPB1, RPBh1, RPO2, RPOL2, RpIILS, hRPB220, hsRPB1
Name
(RefSeq) RNA polymerase II subunit A
  KO
K03006  DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03020  RNA polymerase
hsa03420  Nucleotide excision repair
hsa05016  Huntington disease
Network
nt06502  Nucleotide excision repair
  Element
N01430  Transcription-coupled NER
Disease
H02571  Neurodevelopmental disorder with hypotonia and variable intellectual and behavioral abnormalities
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03020 RNA polymerase
    5430 (POLR2A)
  09124 Replication and repair
   03420 Nucleotide excision repair
    5430 (POLR2A)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    5430 (POLR2A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    5430 (POLR2A)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    5430 (POLR2A)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.6  DNA-directed RNA polymerase
     5430 (POLR2A)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   RNA polymerase II
    Core subunits
     5430 (POLR2A)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    TCR (transcription coupled repair) factors
     DNA-directed RNA polymerase II complex
      5430 (POLR2A)
SSDB
Motif
Pfam: RNA_pol_Rpb1_1 RNA_pol_Rpb1_5 RNA_pol_Rpb1_2 RNA_pol_Rpb1_6 RNA_pol_Rpb1_7 RNA_pol_Rpb1_3 RNA_pol_Rpb1_R RNA_pol_Rpb1_4
Other DBs
NCBI-GeneID: 5430
NCBI-ProteinID: NP_000928
OMIM: 180660
HGNC: 9187
Ensembl: ENSG00000181222
Pharos: P24928(Tbio)
UniProt: P24928 A0AAG2TJB2
Structure
LinkDB
Position
17:7484366..7514616
AA seq 1970 aa
MHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGRPKLGGLMDP
RQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVD
SNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNICEGGEEMDNKFGVEQPEGDEDLTKEKG
HGGCGRYQPRIRRSGLELYAEWKHVNEDSQEKKILLSPERVHEIFKRISDEECFVLGMEP
RYARPEWMIVTVLPVPPLSVRPAVVMQGSARNQDDLTHKLADIVKINNQLRRNEQNGAAA
HVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRVRGNLMGKRVD
FSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKYII
RDNGDRIDLRFHPKPSDLHLQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRILPWS
TFRLNLSVTTPYNADFDGDEMNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVMGIVQD
TLTAVRKFTKRDVFLERGEVMNLLMFLSTWDGKVPQPAILKPRPLWTGKQIFSLIIPGHI
NCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGELIMGILCKKSLGTSAGSLVHISYLEM
GHDITRLFYSNIQTVINNWLLIEGHTIGIGDSIADSKTYQDIQNTIKKAKQDVIEVIEKA
HNNELEPTPGNTLRQTFENQVNRILNDARDKTGSSAQKSLSEYNNFKSMVVSGAKGSKIN
ISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTEFFFHA
MGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGEDGLAGES
VEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQEDLVKDVLSNAHIQNELEREFERMR
EDREVLRVIFPTGDSKVVLPCNLLRMIWNAQKIFHINPRLPSDLHPIKVVEGVKELSKKL
VIVNGDDPLSRQAQENATLLFNIHLRSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAI
AHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAKNVTLGVPRLKELINISKKPKTPSLT
VFLLGQSARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMP
DFDVARISPWLLRVELDRKHMTDRKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIR
IMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKI
IITEDGEFKALQEWILETDGVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKALER
ELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVDVLM
EAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLGAAGPTG
MFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPG
YSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSP
SYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP
TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS
YSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPT
SPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKY
SPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTS
PKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPDDSDEEN
NT seq 5913 nt   +upstreamnt  +downstreamnt
atgcacgggggtggccccccctcgggggacagcgcatgcccgctgcgcaccatcaagaga
gtccagttcggagtcctgagtccggatgaactgaagcgaatgtctgtgacggagggtggc
atcaaatacccagagacgactgagggaggccgccccaagcttggggggctgatggacccg
aggcagggggtgattgagcggactggccgctgccaaacatgtgcaggaaacatgacagag
tgtcctggccactttggccacattgaactggccaagcctgtgtttcacgtgggcttcctg
gtgaagacaatgaaagttttgcgctgtgtctgcttcttctgctccaaactgcttgtggac
tctaacaacccaaagatcaaggatatcctggctaagtccaagggacagcccaagaagcgg
ctcacacatgtctacgacctttgcaagggcaaaaacatatgcgagggtggggaggagatg
gacaacaagttcggtgtggaacaacctgagggtgacgaggatctgaccaaagaaaagggc
catggtggctgtgggcggtaccagcccaggatccggcgttctggcctagagctgtatgcg
gaatggaagcacgttaatgaggactctcaggagaagaagatcctgctgagtccagagcga
gtgcatgagatcttcaaacgcatctcagatgaggagtgttttgtgctgggcatggagccc
cgctatgcacggccagagtggatgattgtcacagtgctgcctgtgcccccgctctccgtg
cggcctgctgttgtgatgcagggctctgcccgtaaccaggatgacctgactcacaaactg
gctgacatcgtgaagatcaacaatcagctgcggcgcaatgagcagaacggcgcagcggcc
catgtcattgcagaggatgtgaagctcctccagttccatgtggccaccatggtggacaat
gagctgcctggcttgccccgtgccatgcagaagtctgggcgtcccctcaagtccctgaag
cagcggttgaagggcaaggaaggccgggtgcgagggaacctgatgggcaaaagagtggac
ttctcggcccgtactgtcatcacccccgaccccaacctctccattgaccaggttggcgtg
ccccgctccattgctgccaacatgacctttgcggagattgtcacccccttcaacattgac
agacttcaagaactagtgcgcagggggaacagccagtacccaggcgccaagtacatcatc
cgagacaatggtgatcgcattgacttgcgtttccaccccaagcccagtgaccttcacctg
cagaccggctataaggtggaacggcacatgtgtgatggggacattgttatcttcaaccgg
cagccaactctgcacaaaatgtccatgatggggcatcgggtccgcattctcccatggtct
acctttcgcttgaatcttagtgtgacaactccgtacaatgcagactttgacggggatgag
atgaacttgcacctgccacagtctctggagacgcgagcagagatccaggagctggccatg
gttcctcgcatgattgtcaccccccagagcaatcggcctgtcatgggtattgtgcaggac
acactcacagcagtgcgcaaattcaccaagagagacgtcttcctggagcggggtgaagtg
atgaacctcctgatgttcctgtcgacgtgggatgggaaggtcccacagccggccatccta
aagccccggcccctgtggacaggcaagcaaatcttctccctcatcatacctggtcacatc
aattgtatccgtacccacagcacccatcccgatgatgaagacagtggcccttacaagcac
atctctcctggggacaccaaggtggtggtggagaatggggagctgatcatgggcatcctg
tgtaagaagtctctgggcacgtcagctggctccctggtccacatctcctacctagagatg
ggtcatgacatcactcgcctcttctactccaacattcagactgtcattaacaactggctc
ctcatcgagggtcatactattggcattggggactccattgctgattctaagacttaccag
gacattcagaacactattaagaaggccaagcaggacgtaatagaggtcatcgagaaggca
cacaacaatgagctggagcccaccccagggaacactctgcggcagacgtttgagaatcag
gtgaaccgcattcttaacgatgcccgagacaagactggctcctctgctcagaaatccctg
tctgaatacaataacttcaagtctatggtcgtgtccggagctaaaggttccaagattaac
atctcccaggtcattgctgtcgttggacagcagaacgtcgagggcaagcggattccattt
ggcttcaagcaccggactctgcctcacttcatcaaggatgactacgggcctgagagccgt
ggctttgtggagaactcctacctagccggcctcacacccactgagttctttttccacgcc
atggggggtcgtgaggggctcattgacacggctgtcaagactgctgagactggatacatc
cagcggcggctgatcaagtccatggagtcagtgatggtgaagtacgacgcgactgtgcgg
aactccatcaaccaggtggtgcagctgcgctacggcgaagacggcctggcaggcgagagc
gttgagttccagaacctggctacgcttaagccttccaacaaggcttttgagaagaagttc
cgctttgattataccaatgagagggccctgcggcgcactctgcaggaggacctggtgaag
gacgtgctgagcaacgcacacatccagaacgagttggagcgggaatttgagcggatgcgg
gaggatcgggaggtgctcagggtcatcttcccaactggagacagcaaggtcgtcctcccc
tgtaacctgctgcggatgatctggaatgctcagaaaatcttccacatcaacccacgcctt
ccctccgacctgcaccccatcaaagtggtggagggagtcaaggaattgagcaagaagctg
gtgattgtgaatggggatgacccactaagtcgacaggcccaggaaaatgccacgctgctc
ttcaacatccacctgcggtccacgttgtgttcccgccgcatggcagaggagtttcggctc
agtggggaggccttcgactggctgcttggggagattgagtccaagttcaaccaagccatt
gcgcatcccggggaaatggtgggggctctggctgcgcagtcccttggagaacctgccacc
cagatgaccttgaataccttccactatgctggtgtgtctgccaagaatgtgacgctgggt
gtgccccgacttaaggagctcatcaacatttccaagaagccaaagactccttcgcttact
gtcttcctgttgggccagtccgctcgagatgctgagagagccaaggatattctgtgccgt
ctggagcatacaacgttgaggaaggtgactgccaacacagccatctactatgaccccaac
ccccagagcacggtggtggcagaggatcaggaatgggtgaatgtctactatgaaatgcct
gactttgatgtggcccgaatctccccctggctgttgcgggtggagctggatcggaagcac
atgactgaccggaagctcaccatggagcagattgctgaaaagatcaatgctggttttggt
gacgacttgaactgcatctttaatgatgacaatgcagagaagctggtgctccgtattcgc
atcatgaacagcgatgagaacaagatgcaagaggaggaagaggtggtggacaagatggat
gatgatgtcttcctgcgctgcatcgagtccaacatgctgacagatatgaccctgcagggc
atcgagcagatcagcaaggtgtacatgcacttgccacagacagacaacaagaagaagatc
atcatcacggaggatggggaattcaaggccctgcaggagtggatcctggagacggacggc
gtgagcttgatgcgggtgctgagtgagaaggacgtggaccccgtacgcaccacgtccaat
gacattgtggagatcttcacggtgctgggcattgaagccgtgcggaaggccctggagcgg
gagctgtaccacgtcatctcctttgatggctcctatgtcaattaccgacacttggctctc
ttgtgtgataccatgacctgtcgtggccacttgatggccatcacccgacacggagtcaac
cgccaggacacaggaccactcatgaagtgttcctttgaggaaacggtggacgtgcttatg
gaagcagccgcacacggtgagagtgaccccatgaagggggtctctgagaatatcatgctg
ggccagctggctccggccggcactggctgctttgacctcctgcttgatgcagagaagtgc
aagtatggcatggagatccccaccaatatccccggcctgggggctgctggacccaccggc
atgttctttggttcagcacccagtcccatgggtggaatctctcctgccatgacaccttgg
aaccagggtgcaacccctgcctatggcgcctggtcccccagtgttgggagtggaatgacc
ccaggggcagccggcttctctcccagtgctgcgtcagatgccagcggcttcagcccaggt
tactcccctgcctggtctcccacaccgggctccccggggtccccaggtccctcaagcccc
tacatcccttcaccaggtggtgccatgtctcccagctactcgccaacgtcacctgcctac
gagccccgctctcctgggggctacacaccccagagtccctcttattcccccacttcaccc
tcctactcccctacctctccatcctattctccaaccagtcccaactatagtcccacatca
cccagctattcgccaacgtcacccagctactcaccgacctctcccagctactcacccacc
tctcccagctactcgcccacctctcccagctactcgcccacctctcccagctactcaccc
acttcccctagctactcgcccacttcccctagctactcgccaacgtctcccagctactcg
ccgacatctcccagctactcgccaacttcacccagctattctcccacttctcccagctac
tcacctacctctccaagctattcacccacctcccccagctactcacccacttccccaagt
tactcacccaccagcccgaactattctccaaccagtcccaattacaccccaacatcaccc
agctacagcccgacatcacccagctattcacctactagtcccaactacacacctaccagc
cctaactacagcccaacctctccaagctactctccaacatcacccagctattccccgacc
tcaccaagttactccccttccagcccacgatacacaccacagtctccaacctatacccca
agctcacccagctacagccccagctcgcccagctacagcccaacctcacccaagtacacc
ccaaccagtccttcttacagtcccagctccccagagtataccccaacctctcccaagtac
tcacctaccagtcccaaatattcacccacctctcccaagtactcgcctaccagtcccacc
tattcacccaccaccccaaaatactccccaacatctcctacttattccccaacctctcca
gtctacaccccaacctctcccaagtactcacctactagccccacttactcgcccacttcc
cccaagtactcgcccaccagccccacctactcgcccacctcccccaaaggctcaacctac
tctcccacttcccctggttactcgcccaccagccccacctacagtctcacaagcccggct
atcagcccggatgacagtgacgaggagaactga

KEGG   Homo sapiens (human): 5431
Entry
5431              CDS       T01001                                 
Symbol
POLR2B, POL2RB, RPB2, hRPB140
Name
(RefSeq) RNA polymerase II subunit B
  KO
K03010  DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03020  RNA polymerase
hsa03420  Nucleotide excision repair
hsa05016  Huntington disease
Network
nt06502  Nucleotide excision repair
  Element
N01430  Transcription-coupled NER
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03020 RNA polymerase
    5431 (POLR2B)
  09124 Replication and repair
   03420 Nucleotide excision repair
    5431 (POLR2B)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    5431 (POLR2B)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    5431 (POLR2B)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    5431 (POLR2B)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.6  DNA-directed RNA polymerase
     5431 (POLR2B)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   RNA polymerase II
    Core subunits
     5431 (POLR2B)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    TCR (transcription coupled repair) factors
     DNA-directed RNA polymerase II complex
      5431 (POLR2B)
SSDB
Motif
Pfam: RNA_pol_Rpb2_6 RNA_pol_Rpb2_1 RNA_pol_Rpb2_2 RNA_pol_Rpb2_7 RNA_pol_Rpb2_4 RNA_pol_Rpb2_3 RNA_pol_Rpb2_5 DUF5817
Other DBs
NCBI-GeneID: 5431
NCBI-ProteinID: NP_000929
OMIM: 180661
HGNC: 9188
Ensembl: ENSG00000047315
Pharos: P30876(Tbio)
UniProt: P30876 B4DH29
Structure
LinkDB
Position
4:56978896..57031158
AA seq 1174 aa
MYDADEDMQYDEDDDEITPDLWQEACWIVISSYFDEKGLVRQQLDSFDEFIQMSVQRIVE
DAPPIDLQAEAQHASGEVEEPPRYLLKFEQIYLSKPTHWERDGAPSPMMPNEARLRNLTY
SAPLYVDITKTVIKEGEEQLQTQHQKTFIGKIPIMLRSTYCLLNGLTDRDLCELNECPLD
PGGYFIINGSEKVLIAQEKMATNTVYVFAKKDSKYAYTGECRSCLENSSRPTSTIWVSML
ARGGQGAKKSAIGQRIVATLPYIKQEVPIIIVFRALGFVSDRDILEHIIYDFEDPEMMEM
VKPSLDEAFVIQEQNVALNFIGSRGAKPGVTKEKRIKYAKEVLQKEMLPHVGVSDFCETK
KAYFLGYMVHRLLLAALGRRELDDRDHYGNKRLDLAGPLLAFLFRGMFKNLLKEVRIYAQ
KFIDRGKDFNLELAIKTRIISDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFASTLS
HLRRLNSPIGRDGKLAKPRQLHNTLWGMVCPAETPEGHAVGLVKNLALMAYISVGSQPSP
ILEFLEEWSMENLEEISPAAIADATKIFVNGCWVGIHKDPEQLMNTLRKLRRQMDIIVSE
VSMIRDIREREIRIYTDAGRICRPLLIVEKQKLLLKKRHIDQLKEREYNNYSWQDLVASG
VVEYIDTLEEETVMLAMTPDDLQEKEVAYCSTYTHCEIHPSMILGVCASIIPFPDHNQSP
RNTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINSIV
AIASYTGYNQEDSVIMNRSAVDRGFFRSVFYRSYKEQESKKGFDQEEVFEKPTRETCQGM
RHAIYDKLDDDGLIAPGVRVSGDDVIIGKTVTLPENEDELESTNRRYTKRDCSTFLRTSE
TGIVDQVMVTLNQEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMPFTCEG
ITPDIIINPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPFNDAVNVQKISNLLSDYGY
HLRGNEVLYNGFTGRKITSQIFIGPTYYQRLKHMVDDKIHSRARGPIQILNRQPMEGRSR
DGGLRFGEMERDCQIAHGAAQFLRERLFEASDPYQVHVCNLCGIMAIANTRTHTYECRGC
RNKTQISLVRMPYACKLLFQELMSMSIAPRMMSV
NT seq 3525 nt   +upstreamnt  +downstreamnt
atgtacgacgcggatgaggatatgcaatatgatgaggatgatgatgaaatcaccccggat
ttgtggcaagaagcatgctggattgtaatcagttcctattttgacgagaaaggcttggtt
agacaacagctggattcttttgatgagtttattcagatgtctgttcaaagaattgtggaa
gacgctcctcctatagacctacaggctgaagctcagcatgctagtggagaagttgaagaa
ccgccacgatatttgctgaagtttgaacaaatttatctttccaagcctacccattgggaa
agagatggtgctccttcaccaatgatgcccaatgaagctagattaaggaatctcacgtat
tctgctccgctttatgttgatataacaaaaacagtcattaaagaaggtgaagaacaactt
cagactcagcatcagaaaacttttataggaaaaattccaattatgttgcggtcaacttac
tgccttttgaatggcttgacagatcgtgatctttgtgagttaaatgaatgccctttggat
cctggtggctatttcattattaatggatcagaaaaggttctgattgcccaagagaaaatg
gcaacaaacacagtttatgtgtttgccaaaaaggattctaaatatgcctacacaggagag
tgtagatcatgtcttgagaattcttcccgacccaccagtactatatgggttagcatgctg
gcaagaggaggacagggtgccaagaagagtgctattggtcagcgcattgtggcaactcta
ccatatatcaagcaagaagttcccatcattattgtgttcagagcattaggttttgtgtcc
gacagagatattttagaacatattatttatgattttgaagatccagagatgatggaaatg
gttaaaccttctctcgatgaagcttttgtcatccaagaacagaatgttgcactaaatttc
attggttcaagaggagcaaagcctggtgttactaaagagaaaagaattaaatatgcaaag
gaagttttacaaaaagaaatgctccctcatgttggtgtcagtgatttttgtgagaccaaa
aaagcctatttcttgggatacatggttcataggttacttctggcagctttgggtagaaga
gaactagatgacagagatcactatggaaacaagagattggatcttgctgggccgctgctt
gcattcttatttagaggtatgtttaagaatttgcttaaagaagtgcggatctatgcacag
aaatttattgatcgaggaaaggattttaacttggagttggcaattaaaacacggatcata
tctgatggcctaaaatactctttagctactggaaactggggtgatcaaaagaaagctcat
caagccagagctggagtatctcaggtgttaaaccgcctgacttttgcgtctactctttct
cacctgcgtcgtttaaattctcctattggtagagacggcaagctagcaaaaccaagacag
ttgcataatacgttgtggggaatggtgtgtcctgccgagaccccagagggccatgctgta
ggacttgtgaagaatttagccttgatggcgtatatttcagttggatctcaaccatctcca
attctggaatttttagaagaatggagtatggaaaatttagaagaaatttctcctgcagct
attgctgatgcaaccaagatttttgttaatggctgctgggttggaatacataaagatccc
gaacaacttatgaacaccctaaggaaattgagacgtcagatggacatcattgtgtctgaa
gtttctatgatcagagatattcgagagagggagattcggatctatacggatgcaggccgt
atttgtagaccacttctgattgtggaaaaacaaaagctacttttgaagaagaggcatatt
gaccaattgaaagagagagaatataacaactatagttggcaggatcttgtggccagtggg
gtagtggagtatattgataccctggaagaagaaacagtgatgcttgcaatgactccagat
gatttacaggagaaagaagtagcttattgttccacatatacacactgtgagattcatccc
tcaatgatccttggtgtctgtgcatctattattccctttcctgatcataaccagtcccct
agaaacacataccagtctgctatgggtaagcaggctatgggagtttacatcaccaacttc
catgttcgcatggacacattggcccatgttctctattatcctcaaaagccacttgtgact
acacggtctatggaatatctacgatttagagagctgccagcaggcatcaactcaattgtg
gccattgcatcatacactggatataatcaggaagactctgttatcatgaatcgttcagct
gtagaccgcggcttcttcaggtctgttttctatcgctcatacaaagaacaggagtctaaa
aaaggatttgatcaagaagaagtttttgagaagcctacacgtgaaacatgccagggcatg
aggcatgccatttacgacaagctggatgatgatggtttgatagctccaggggttcgtgta
tcaggagatgatgttattataggcaaaacagtcaccttgcctgaaaatgaagatgaattg
gagagcaccaatagacgctataccaagagagactgtagcacttttctcagaactagcgag
acgggcattgtggatcaggttatggtaactctcaatcaggaaggatataaattttgtaaa
ataagggtacgctctgttaggattccacagattggagacaaatttgctagtcgacatggt
caaaagggtacttgtggtattcagtatagacaagaggatatgcctttcacctgtgaaggt
atcacccctgatatcatcatcaatccccatgccatcccctctcgtatgactattggtcac
ttaattgaatgccttcaagggaaggtatcggctaacaagggtgaaattggtgatgccact
ccatttaatgatgctgttaacgtgcagaagatttctaatcttttatctgattatggctat
catctcagaggaaatgaggtcctgtacaatgggttcactggtcgaaaaatcacatcacaa
atatttattggccccacttattaccagcgtttgaagcatatggtggatgataagattcac
tctcgtgctaggggacctattcagatcctcaatagacagcccatggagggtagatctcgt
gatggtggcctgcgttttggagaaatggaacgagattgtcagattgcccatggagcagcc
cagtttttaagggaaagattgtttgaggcatcagatccatatcaggttcatgtttgcaat
ctttgtggaataatggcgattgccaacaccaggacccatacatatgaatgcaggggctgc
cgcaataaaacccagatttctttggtgcgaatgccttacgcatgcaaactattgtttcag
gaacttatgtctatgagtattgcaccgcgaatgatgagtgtttag

KEGG   Homo sapiens (human): 5432
Entry
5432              CDS       T01001                                 
Symbol
POLR2C, RPB3, RPB31, hRPB33, hsRPB3
Name
(RefSeq) RNA polymerase II subunit C
  KO
K03011  DNA-directed RNA polymerase II subunit RPB3
Organism
hsa  Homo sapiens (human)
Pathway
hsa03020  RNA polymerase
hsa03420  Nucleotide excision repair
hsa05016  Huntington disease
Network
nt06502  Nucleotide excision repair
  Element
N01430  Transcription-coupled NER
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03020 RNA polymerase
    5432 (POLR2C)
  09124 Replication and repair
   03420 Nucleotide excision repair
    5432 (POLR2C)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    5432 (POLR2C)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    5432 (POLR2C)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    5432 (POLR2C)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   RNA polymerase II
    Core subunits
     5432 (POLR2C)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    TCR (transcription coupled repair) factors
     DNA-directed RNA polymerase II complex
      5432 (POLR2C)
SSDB
Motif
Pfam: RNA_pol_A_bac RNA_pol_L
Other DBs
NCBI-GeneID: 5432
NCBI-ProteinID: NP_116558
OMIM: 180663
HGNC: 9189
Ensembl: ENSG00000102978
Pharos: P19387(Tbio)
UniProt: P19387 Q6FGR6
Structure
LinkDB
Position
16:57462679..57472009
AA seq 275 aa
MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLH
DEFIAHRLGLIPLISDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDL
ISNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTA
GVAFEYDPDNALRHTVYPKPEEWPKSEYSELDEDESQAPYDPNGKPERFYYNVESCGSLR
PETIVLSALSGLKKKLSDLQTQLSHEIQSDVLTIN
NT seq 828 nt   +upstreamnt  +downstreamnt
atgccgtacgccaaccagcctaccgtgcggatcacggagctcactgacgagaatgtcaag
ttcatcatcgagaacaccgacctggcggtggccaattcgattcggagggtcttcatcgct
gaggttcccataatagccattgactgggttcagattgatgccaattcctcagttcttcat
gatgaattcattgctcacaggcttggattaattcccctcattagtgatgacattgtggac
aagctgcagtactctcgggactgcacatgtgaggagttctgccccgagtgctcggtggag
ttcaccctcgatgtgcggtgcaatgaagaccagacgcgacatgtcacgtctcgagacctc
atctccaacagcccccgggtcattccggtgacatcccggaaccgagataatgaccccaat
gactacgtggagcaggatgacatcctcatcgtcaagttgagaaagggccaggagctgaga
cttcgagcctatgccaaaaagggctttggcaaggagcatgccaagtggaaccctactgca
ggggtggcttttgaatacgatccagacaatgccctgaggcacacagtgtaccccaagccc
gaggaatggccaaagagtgagtactcggagctggatgaggatgagtcgcaggctccctat
gaccccaacggcaagccagaaaggttttactacaatgtggagtcctgtggctctctgcgt
cctgaaaccattgtcctgtcagccctctcaggattgaagaagaaactgagtgatttacaa
actcaattaagccacgagatccagagtgatgtgctaaccataaattaa

KEGG   Homo sapiens (human): 5433
Entry
5433              CDS       T01001                                 
Symbol
POLR2D, HSRBP4, HSRPB4, RBP4, RPB16, RPB4
Name
(RefSeq) RNA polymerase II subunit D
  KO
K03012  DNA-directed RNA polymerase II subunit RPB4
Organism
hsa  Homo sapiens (human)
Pathway
hsa03020  RNA polymerase
hsa03420  Nucleotide excision repair
hsa05016  Huntington disease
Network
nt06502  Nucleotide excision repair
  Element
N01430  Transcription-coupled NER
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03020 RNA polymerase
    5433 (POLR2D)
  09124 Replication and repair
   03420 Nucleotide excision repair
    5433 (POLR2D)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    5433 (POLR2D)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    5433 (POLR2D)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    5433 (POLR2D)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   RNA polymerase II
    Pol II specific subunits
     5433 (POLR2D)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    TCR (transcription coupled repair) factors
     DNA-directed RNA polymerase II complex
      5433 (POLR2D)
SSDB
Motif
Pfam: RNA_pol_Rpb4 Maelstrom Tfb4
Other DBs
NCBI-GeneID: 5433
NCBI-ProteinID: NP_004796
OMIM: 606017
HGNC: 9191
Ensembl: ENSG00000144231
Pharos: O15514(Tdark)
UniProt: O15514
Structure
LinkDB
Position
2:complement(127843553..127858155)
AA seq 142 aa
MAAGGSDPRAGDVEEDASQLIFPKEFETAETLLNSEVHMLLEHRKQQNESAEDEQELSEV
FMKTLNYTARFSRFKNRETIASVRSLLLQKKLHKFELACLANLCPETAEESKALIPSLEG
RFEDEELQQILDDIQTKRSFQY
NT seq 429 nt   +upstreamnt  +downstreamnt
atggcggcgggtggcagcgatccgcgggctggcgacgtagaggaggacgcctcacagctc
atctttcctaaagagtttgaaacagctgagacacttctaaattcagaagttcatatgctt
ctggaacatcgaaagcagcagaatgagagtgcagaggacgaacaggagctctcagaagtc
ttcatgaaaacattaaactacacagcccgtttcagtcgtttcaaaaacagagagaccatt
gccagtgttcgtagcttgctactccagaaaaagcttcataagtttgagttggcctgtttg
gccaacctttgcccagagactgctgaggagtccaaggctctaatcccaagcttggaggga
cggtttgaagatgaggagctgcagcagattcttgatgatatccagacaaagcgcagcttt
cagtattaa

KEGG   Homo sapiens (human): 5434
Entry
5434              CDS       T01001                                 
Symbol
POLR2E, RPABC1, RPB5, XAP4, hRPB25, hsRPB5
Name
(RefSeq) RNA polymerase II, I and III subunit E
  KO
K03013  DNA-directed RNA polymerases I, II, and III subunit RPABC1
Organism
hsa  Homo sapiens (human)
Pathway
hsa03020  RNA polymerase
hsa03420  Nucleotide excision repair
hsa04623  Cytosolic DNA-sensing pathway
hsa05016  Huntington disease
Network
nt06502  Nucleotide excision repair
  Element
N01430  Transcription-coupled NER
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03020 RNA polymerase
    5434 (POLR2E)
  09124 Replication and repair
   03420 Nucleotide excision repair
    5434 (POLR2E)
 09150 Organismal Systems
  09151 Immune system
   04623 Cytosolic DNA-sensing pathway
    5434 (POLR2E)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    5434 (POLR2E)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    5434 (POLR2E)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    5434 (POLR2E)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   RNA polymerase II
    Pol I, II, III common subunits
     5434 (POLR2E)
  RNA polymerase III system
   RNA polymerase III
     5434 (POLR2E)
  RNA polymerase I system
   RNA polymerase I
     5434 (POLR2E)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    TCR (transcription coupled repair) factors
     DNA-directed RNA polymerase II complex
      5434 (POLR2E)
SSDB
Motif
Pfam: RNA_pol_Rpb5_C RNA_pol_Rpb5_N
Other DBs
NCBI-GeneID: 5434
NCBI-ProteinID: NP_002686
OMIM: 180664
HGNC: 9192
Ensembl: ENSG00000099817
Pharos: P19388(Tbio)
UniProt: P19388 E5KT65
Structure
LinkDB
Position
19:complement(1086574..1095375)
AA seq 210 aa
MDDEEETYRLWKIRKTIMQLCHDRGYLVTQDELDQTLEEFKAQSGDKPSEGRPRRTDLTV
LVAHNDDPTDQMFVFFPEEPKVGIKTIKVYCQRMQEENITRALIVVQQGMTPSAKQSLVD
MAPKYILEQFLQQELLINITEHELVPEHVVMTKEEVTELLARYKLRENQLPRIQAGDPVA
RYFGIKRGQVVKIIRPSETAGRYITYRLVQ
NT seq 633 nt   +upstreamnt  +downstreamnt
atggacgacgaggaggagacgtaccggctctggaaaatccgcaagaccatcatgcagctg
tgccacgaccgtggctatctggtgacccaggacgagcttgaccagaccctggaggagttc
aaagcccaatctggggacaagccgagtgaggggcggccgcggcgcacggacctcaccgtg
ctggtggcccacaacgatgaccccaccgaccagatgtttgtgttctttccagaggagccc
aaggtgggcatcaagaccatcaaggtgtactgccagcgcatgcaggaggagaacatcaca
cgggctctcatcgtggtgcagcagggcatgacaccctccgccaagcagtccctggtcgac
atggcccccaagtacatcctggagcagtttctgcagcaggagctgctcatcaacatcacg
gagcacgagctagtccctgagcacgtcgtcatgaccaaggaggaggtgacagagctgctg
gcccgatataagctccgagagaaccagctgcccaggatccaggcgggggaccctgtggcg
cgctactttgggataaagcgtgggcaggtggtgaagatcatccggcccagtgagacggct
ggcaggtacatcacctaccggctggtgcagtag

KEGG   Homo sapiens (human): 5435
Entry
5435              CDS       T01001                                 
Symbol
POLR2F, HRBP14.4, POLRF, RPABC14.4, RPABC2, RPB14.4, RPB6, RPC15
Name
(RefSeq) RNA polymerase II, I and III subunit F
  KO
K03014  DNA-directed RNA polymerases I, II, and III subunit RPABC2
Organism
hsa  Homo sapiens (human)
Pathway
hsa03020  RNA polymerase
hsa03420  Nucleotide excision repair
hsa04623  Cytosolic DNA-sensing pathway
hsa05016  Huntington disease
Network
nt06502  Nucleotide excision repair
  Element
N01430  Transcription-coupled NER
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03020 RNA polymerase
    5435 (POLR2F)
  09124 Replication and repair
   03420 Nucleotide excision repair
    5435 (POLR2F)
 09150 Organismal Systems
  09151 Immune system
   04623 Cytosolic DNA-sensing pathway
    5435 (POLR2F)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    5435 (POLR2F)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    5435 (POLR2F)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    5435 (POLR2F)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   RNA polymerase II
    Pol I, II, III common subunits
     5435 (POLR2F)
  RNA polymerase III system
   RNA polymerase III
     5435 (POLR2F)
  RNA polymerase I system
   RNA polymerase I
     5435 (POLR2F)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    TCR (transcription coupled repair) factors
     DNA-directed RNA polymerase II complex
      5435 (POLR2F)
SSDB
Motif
Pfam: RNA_pol_Rpb6
Other DBs
NCBI-GeneID: 5435
NCBI-ProteinID: NP_068809
OMIM: 604414
HGNC: 9193
Ensembl: ENSG00000100142
Pharos: P61218(Tbio)
UniProt: P61218
Structure
LinkDB
Position
22:37953663..38041915
AA seq 127 aa
MSDNEDNFDGDDFDDVEEDEGLDDLENAEEEGQENVEILPSGERPQANQKRITTPYMTKY
ERARVLGTRALQIAMCAPVMVELEGETDPLLIAMKELKARKIPIIIRRYLPDGSYEDWGV
DELIITD
NT seq 384 nt   +upstreamnt  +downstreamnt
atgtcagacaacgaggacaattttgatggcgacgactttgatgatgtggaggaggatgaa
gggctagatgacttggagaatgccgaagaggaaggccaggagaatgtcgagatcctcccc
tctggggagcgaccgcaggccaaccagaagcgaatcaccacaccatacatgaccaagtac
gagcgagcccgcgtgctgggcacccgagcgctccagattgcgatgtgtgcccctgtgatg
gtggagctggagggggagacagatcctctgctcattgccatgaaggaactcaaggcccga
aagatccccatcatcattcgccgttacctgccagatgggagctatgaagactggggggtg
gacgagctcatcatcaccgactga

KEGG   Homo sapiens (human): 5436
Entry
5436              CDS       T01001                                 
Symbol
POLR2G, RPB19, RPB7, hRPB19, hsRPB7
Name
(RefSeq) RNA polymerase II subunit G
  KO
K03015  DNA-directed RNA polymerase II subunit RPB7
Organism
hsa  Homo sapiens (human)
Pathway
hsa03020  RNA polymerase
hsa03420  Nucleotide excision repair
hsa05016  Huntington disease
Network
nt06502  Nucleotide excision repair
  Element
N01430  Transcription-coupled NER
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03020 RNA polymerase
    5436 (POLR2G)
  09124 Replication and repair
   03420 Nucleotide excision repair
    5436 (POLR2G)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    5436 (POLR2G)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    5436 (POLR2G)
   03019 Messenger RNA biogenesis [BR:hsa03019]
    5436 (POLR2G)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    5436 (POLR2G)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   RNA polymerase II
    Pol II specific subunits
     5436 (POLR2G)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    P-body specific factors
     5436 (POLR2G)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    TCR (transcription coupled repair) factors
     DNA-directed RNA polymerase II complex
      5436 (POLR2G)
SSDB
Motif
Pfam: S1 SHS2_Rpb7-N
Other DBs
NCBI-GeneID: 5436
NCBI-ProteinID: NP_002687
OMIM: 602013
HGNC: 9194
Ensembl: ENSG00000168002
Pharos: P62487(Tbio)
UniProt: P62487
Structure
LinkDB
Position
11:62761580..62766710
AA seq 172 aa
MFYHISLEHEILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKYGFVIAVTTIDNIGAGVIQ
PGRGFVLYPVKYKAIVFRPFKGEVVDAVVTQVNKVGLFTEIGPMSCFISRHSIPSEMEFD
PNSNPPCYKTMDEDIVIQQDDEIRLKIVGTRVDKNDIFAIGSLMDDYLGLVS
NT seq 519 nt   +upstreamnt  +downstreamnt
atgttctaccatatctccctagagcacgaaatcctgctgcacccgcgctacttcggcccc
aacttgctcaacacggtgaagcagaagctcttcaccgaggtggaggggacctgcacaggg
aagtatggctttgtaattgctgtcaccaccattgacaatattggtgctggtgtgatccag
ccaggccgaggctttgtcctttatccagttaagtacaaggccattgttttccggccattt
aaaggggaggtcgtggatgctgttgtcactcaggtcaacaaggttggactcttcacagaa
attgggcccatgtcttgcttcatctctcgacattccatcccttcagagatggagtttgat
cctaactccaacccaccatgttacaagacaatggatgaggatattgtgattcagcaggac
gatgagatccgcttaaagattgtggggacccgtgtggacaagaatgacatttttgctatt
ggctccctgatggacgattacttggggcttgtaagctga

KEGG   Homo sapiens (human): 5437
Entry
5437              CDS       T01001                                 
Symbol
POLR2H, RPABC3, RPB17, RPB8
Name
(RefSeq) RNA polymerase II, I and III subunit H
  KO
K03016  DNA-directed RNA polymerases I, II, and III subunit RPABC3
Organism
hsa  Homo sapiens (human)
Pathway
hsa03020  RNA polymerase
hsa03420  Nucleotide excision repair
hsa04623  Cytosolic DNA-sensing pathway
hsa05016  Huntington disease
Network
nt06502  Nucleotide excision repair
  Element
N01430  Transcription-coupled NER
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03020 RNA polymerase
    5437 (POLR2H)
  09124 Replication and repair
   03420 Nucleotide excision repair
    5437 (POLR2H)
 09150 Organismal Systems
  09151 Immune system
   04623 Cytosolic DNA-sensing pathway
    5437 (POLR2H)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    5437 (POLR2H)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    5437 (POLR2H)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    5437 (POLR2H)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   RNA polymerase II
    Pol I, II, III common subunits
     5437 (POLR2H)
  RNA polymerase III system
   RNA polymerase III
     5437 (POLR2H)
  RNA polymerase I system
   RNA polymerase I
     5437 (POLR2H)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    TCR (transcription coupled repair) factors
     DNA-directed RNA polymerase II complex
      5437 (POLR2H)
SSDB
Motif
Pfam: RNA_pol_Rpb8 RNA_pol_RpbG
Other DBs
NCBI-GeneID: 5437
NCBI-ProteinID: NP_006223
OMIM: 606023
HGNC: 9195
Ensembl: ENSG00000163882
Pharos: P52434(Tbio)
UniProt: P52434
Structure
LinkDB
Position
3:184361710..184368591
AA seq 150 aa
MAGILFEDIFDVKDIDPEGKKFDRVSRLHCESESFKMDLILDVNIQIYPVDLGDKFRLVI
ASTLYEDGTLDDGEYNPTDDRPSRADQFEYVMYGKVYRIEGDETSTEAATRLSAYVSYGG
LLMRLQGDANNLHGFEVDSRVYLLMKKLAF
NT seq 453 nt   +upstreamnt  +downstreamnt
atggcgggcatcctgtttgaggatattttcgatgtgaaggatattgacccggagggcaag
aagtttgaccgagtgtctcgactgcattgtgagagtgaatctttcaagatggatctaatc
ttagatgtaaacattcaaatttaccctgtagacttgggtgacaagtttcggttggtcata
gctagtaccttgtatgaagatggtaccctggatgatggtgaatacaaccccactgatgat
aggccttccagggctgaccagtttgagtatgtaatgtatggaaaagtgtacaggattgag
ggagatgaaacttctactgaagcagcaacacgcctctctgcgtacgtgtcctatgggggc
ctgctcatgaggctgcagggggatgccaacaacctgcatggattcgaggtggactccaga
gtttatctcctgatgaagaagctagccttctga

KEGG   Homo sapiens (human): 5438
Entry
5438              CDS       T01001                                 
Symbol
POLR2I, RPB9, hRPB14.5
Name
(RefSeq) RNA polymerase II subunit I
  KO
K03017  DNA-directed RNA polymerase II subunit RPB9
Organism
hsa  Homo sapiens (human)
Pathway
hsa03020  RNA polymerase
hsa03420  Nucleotide excision repair
hsa05016  Huntington disease
Network
nt06502  Nucleotide excision repair
  Element
N01430  Transcription-coupled NER
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03020 RNA polymerase
    5438 (POLR2I)
  09124 Replication and repair
   03420 Nucleotide excision repair
    5438 (POLR2I)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    5438 (POLR2I)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    5438 (POLR2I)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    5438 (POLR2I)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   RNA polymerase II
    Pol II specific subunits
     5438 (POLR2I)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    TCR (transcription coupled repair) factors
     DNA-directed RNA polymerase II complex
      5438 (POLR2I)
SSDB
Motif
Pfam: RNA_POL_M_15KD TFIIS_C Zn_ribbon_recom Ogr_Delta TtuA_LIM_N DZR
Other DBs
NCBI-GeneID: 5438
NCBI-ProteinID: NP_006224
OMIM: 180662
HGNC: 9196
Ensembl: ENSG00000105258
Pharos: P36954(Tbio)
UniProt: P36954
Structure
LinkDB
Position
19:complement(36113709..36114875)
AA seq 125 aa
MEPDGTYEPGFVGIRFCQECNNMLYPKEDKENRILLYACRNCDYQQEADNSCIYVNKITH
EVDELTQIIADVSQDPTLPRTEDHPCQKCGHKEAVFFQSHSARAEDAMRLYYVCTAPHCG
HRWTE
NT seq 378 nt   +upstreamnt  +downstreamnt
atggagcccgacgggacttacgagccgggcttcgtgggtattcgcttctgccaggaatgt
aacaacatgctgtaccccaaggaagacaaggagaaccgcattctgctctacgcgtgccgg
aactgtgattaccagcaggaggccgacaacagctgcatctatgtcaacaagatcacgcac
gaagtggacgaactgacccagattatcgccgacgtgtcccaggaccccacgttgccgcgg
accgaggaccacccgtgccaaaagtgcggccacaaggaggctgtgttcttccagtcacac
agtgcgcgggccgaggacgccatgcgcctttactacgtgtgcacagccccacactgcggc
caccgctggaccgagtga

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