KEGG   Homo sapiens (human): 253959
Entry
253959            CDS       T01001                                 
Symbol
RALGAPA1, GARNL1, GRIPE, NEDHRIT, RalGAPalpha1, TULIP1, p240
Name
(RefSeq) Ral GTPase activating protein catalytic subunit alpha 1
  KO
K25768  Ral GTPase-activating protein subunit alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
Disease
H02397  Neurodevelopmental disorder with movement abnormalities or hypotonia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    253959 (RALGAPA1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    253959 (RALGAPA1)
Membrane trafficking [BR:hsa04131]
 Exocytosis
  Tethering complex
   Exocyst complex assembly proteins
    253959 (RALGAPA1)
SSDB
Motif
Pfam: Rap_GAP RALGAPB_N
Other DBs
NCBI-GeneID: 253959
NCBI-ProteinID: NP_001333172
OMIM: 608884
HGNC: 17770
Ensembl: ENSG00000174373
UniProt: Q6GYQ0
LinkDB
Position
14:complement(35538356..35809295)
AA seq 2036 aa
MFSKKPHGDVKKSTQKVLDTKKDALTRLKHLRIVIENAESIDLKQFFDQHFSHIYYVFFE
NFVTIEASLKQKGHKSQREELDAILFIFEKILQLLPERIHQRWQFHSIGLILKKLLHTGN
SLKIRREGVRLFLLWLQALQNNCSKEQLWMFSCLIPGFSAPQSEHGPRTLDNLINPPLNL
QETQVTIEEITPLVPPQSGDKGQEDLTSYFLEALLKYIVIQVKSLEWKNKENQERGFSFL
FSHFKKYYLPYIFPNICKENSLYHPILDIPQMRPKPHYVVIKKDAETNEAIYCTKEPFIK
ARVIVIRWLVSFWLEPKPHTGPHIPGMEGEVLPKNIQRAAASLVSREESKNDNADKTDRT
TEPEQSHSNTSTLTEREPSSSSLCSIDEEHLTDIEIVRRVFSSKRSNVNFVTEIFRQAFL
LPICEAAAMRKVVKVYQEWIQQEEKPLFMQEPEEIVITSSDLPCIENVTDHDISMEEGEK
REEENGTNTADHVRNSSWAKNGSYQGALHNASEEATEQNIRAGTQAVLQVFIINSSNIFL
LEPANEIKNLLDEHTDMCKRILNIYRYMVVQVSMDKKTWEQMLLVLLRVTESVLKMPSQA
FLQFQGKKNMTLAGRLAGPLFQTLIVAWIKANLNVYISRELWDDLLSVLSSLTYWEELAT
EWSLTMETLTKVLARNLYSLDLSDLPLDKLSEQKQKKHKGKGVGHEFQKVSVDKSFSRGW
SRDQPGQAPMRQRSATTTGSPGTEKARSIVRQKTVDIDDAQILPRSTRVRHFSQSEETGN
EVFGALNEEQPLPRSSSTSDILEPFTVERAKVNKEDMSQKLPPLNSDIGGSSANVPDLMD
EFIAERLRSGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPIDDPGVPSEWTSPASAG
SSDLISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVTSSADVDSGSGHHQSAEEQEVASLT
TLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPSTLNIDHMEQKDLQL
DEKLHHSVLQTPDDLEISEFPSECCSVMAGGTLTGWHADVATVMWRRMLGILGDVNSIMD
PEIHAQVFDYLCELWQNLAKIRDNLGISTDNLTSPSPPVLIPPLRILTPWLFKATMLTDK
YKQGKLHAYKLICNTMKRRQDVSPNRDFLTHFYNIMHCGLLHIDQDIVNTIIKHCSPQFF
SLGLPGATMLIMDFIVAAGRVASSAFLNAPRVEAQVLLGSLVCFPNLYCELPSLHPNIPD
VAVSQFTDVKELIIKTVLSSARDEPSGPARCVALCSLGIWICEELVHESHHPQIKEALNV
ICVSLKFTNKTVAHVACNMLHMLVHYVPRLQIYQPDSPLKIIQILIATITHLLPSTEASS
YEMDKRLVVSLLLCLLDWIMALPLKTLLQPFHATGAESDKTEKSVLNCIYKVLHGCVYGA
QCFSNPRYFPMSLSDLASVDYDPFMHLESLKEPEPLHSPDSERSSKLQPVTEVKTQMQHG
LISIAARTVITHLVNHLGHYPMSGGPAMLTSQVCENHDNHYSESTELSPELFESPNIQFF
VLNNTTLVSCIQIRSEENMPGGGLSAGLASANSNVRIIVRDLSGKYSWDSAILYGPPPVS
GLSEPTSFMLSLSHQEKPEEPPTSNECLEDITVKDGLSLQFKRFRETVPTWDTIRDEEDV
LDELLQYLGVTSPECLQRTGISLNIPAPQPVCISEKQENDVINAILKQHTEEKEFVEKHF
NDLNMKAVEQDEPIPQKPQSAFYYCRLLLSILGMNSWDKRRSFHLLKKNEKLLRELRNLD
SRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTNHCGFMGGLQK
NKSTGLTTPYFATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHTRDYRRG
IIPTEFGDVLIVIYPMKNHMFSIQIMKKPEVPFFGPLFDGAIVNGKVLPIMVRATAINAS
RALKSLIPLYQNFYEERARYLQTIVQHHLEPTTFEDFAAQVFSPAPYHHLPSDADH
NT seq 6111 nt   +upstreamnt  +downstreamnt
atgttctccaagaagccgcacggggacgtgaagaagtccacccagaaggtgctagacacc
aagaaggacgcactgactcgcctcaagcacctgcgcatcgtcatcgagaatgcagaatct
attgatcttaaacagtttttcgaccaacatttttcacatatatactatgtgttctttgaa
aattttgtgactattgaagctagtcttaaacagaaaggtcacaagtctcaaagagaggaa
ttggatgctatactttttatttttgagaaaattttacaacttcttccagaaagaattcat
cagcgatggcagtttcatagtattggattgattttaaagaagctacttcacacaggaaac
tccttaaagattaggcgggaaggtgttcgtcttttcttactatggttgcaagctcttcag
aataactgtagcaaagaacagctctggatgttttcatgcttaatccctggattttcagca
ccacagtctgaacatggacctcgaactttagataatctcattaatcctccactcaacctt
caagaaactcaagtcactatagaagaaatcactcctcttgtccccccacaatcaggagat
aaagggcaagaagatctcacaagctattttcttgaagcacttctaaaatacatagtcatt
caggtaaaaagtttagaatggaagaacaaagaaaaccaagaaaggggattttcatttttg
ttttcacattttaagaaatattacttgccttatatttttccaaacatctgtaaggaaaac
agtttatatcatcctatacttgacatcccgcagatgagaccaaagccacattatgtcgtg
ataaagaaagatgctgaaaccaatgaagcaatctattgtacaaaggagcctttcattaag
gctcgtgttattgtcattcgttggctggtttctttctggctggagccaaaaccacataca
ggacctcatattcctgggatggaaggtgaagtcttgccaaagaatattcagagagcagct
gctagtttagtatccagagaagaaagcaaaaatgataatgctgataaaacagacagaact
acagaacccgaacagtctcattccaatacaagcactctcacggagcgagaacctagctca
tctagtctctgtagtattgatgaagaacatctcacagacattgaaatagttcgcagagtt
ttttcttctaaaaggagtaatgtaaactttgtgacagagatatttcgtcaggcattttta
ttaccaatttgtgaagcagcagctatgagaaaagtggtaaaagtatatcaagaatggatc
caacaagaggaaaaacctttgttcatgcaagagcctgaagaaattgtgatcacttcttca
gacctcccttgcattgaaaatgtcacagaccatgatatttcaatggaagaaggagaaaaa
agagaagaggaaaatgggaccaatactgctgatcatgttcgaaattccagttgggcaaaa
aacggctcctaccaaggtgctcttcataacgcctctgaagaagccacagaacaaaacata
cgagctggtacccaggcagttttgcaggtgtttattataaactcatcaaatatatttctt
cttgaacctgcaaatgaaataaaaaatcttctggatgaacacacagatatgtgtaaacgc
attcttaacatttatcggtacatggttgtacaagtatcaatggacaaaaagacttgggaa
cagatgctgcttgtgttgctcagagtcacggaatctgtactgaagatgccatcacaagct
tttctacagttccaagggaaaaaaaatatgaccttggcaggtcgacttgcaggaccactt
ttccagacccttatagttgcctggatcaaagcaaacctaaatgtgtacatctcccgagaa
ctttgggatgacttactgtcagtattgtcatcgctgacctattgggaagagttggccact
gagtggtcactgactatggagacattaactaaagttttagctaggaatttatatagtttg
gatctcagtgatttaccattggataagctgagtgaacagaaacaaaaaaagcacaaaggg
aaaggagttggacatgaatttcagaaagtttcagttgacaagtcattttctagaggatgg
agtcgtgatcagcctggccaagccccaatgagacagaggagtgcaacaaccactggttct
ccaggaaccgaaaaggcgaggagtatagtacggcaaaaaactgtcgatattgatgatgct
caaatacttccccgctcaactagagtcagacatttttcacaaagtgaagaaactggaaat
gaagtttttggtgctttgaatgaggagcagccattgcctcgaagtagcagcacttctgac
atcttggaaccattcactgttgaacgagccaaagtcaataaagaggacatgagccaaaaa
ctgcctcctcttaatagtgatattggcggcagcagtgctaatgttcctgatctgatggat
gagtttatagcagaacgacttcgaagtggtaatgcctcgactatgacaagaagaggaagt
agtccaggcagcctggaaattcccaaagacctccctgatattctaaacaagcagaaccag
atgcgccctattgatgacccaggtgtgccctcagaatggacttctcctgccagtgcaggg
agcagtgatcttatcagctcagatagtcattcggattctttcagcgctttccaatatgat
ggccgaaaatttgacaattttggctttggaaccgacactggggttacgtcctctgctgat
gtggattcaggttctggccatcatcagagtgctgaagagcaggaagtggctagtctaact
actcttcatatagattctgaaacaagcagtcttaatcagcaagctttctctgctgaagtt
gcaactattactggttcagaaagtgcttccccagtccactcacctctgggctccaggtca
cagactccttccccttctacattgaatatagatcacatggaacagaaggatctgcagctc
gacgagaagctccaccactctgttcttcagacaccagatgatctagaaattagtgaattt
ccatcagaatgttgtagtgtgatggcaggaggtactctgactggatggcatgctgatgtt
gctactgtaatgtggcgaagaatgctaggcattttgggagatgtaaattcaatcatggat
cctgaaatacatgctcaagtttttgattacctctgtgaactttggcagaatctagctaag
attagagataaccttggcatttcaactgataacctgacctccccttctccaccagtttta
attcctccactgagaattcttacaccttggctttttaaggcaaccatgttgactgataaa
tataaacaaggtaaattacatgcatataaacttatttgtaatacaatgaaaagaagacaa
gatgtttctccaaatagagattttctaacacatttctacaatataatgcattgtggatta
cttcatattgaccaggatattgtcaatacaatcatcaaacactgctcacctcaatttttt
tcacttggtttgcctggtgccacaatgcttattatggattttattgtagcagctggtaga
gtggcttcttcagcttttctcaatgcaccaagagtagaagcacaagttcttctgggatct
ttggtttgctttcccaacttatattgtgaactgccttctcttcatcccaacattcctgat
gttgctgtgtctcagtttacagatgttaaggaacttataatcaaaactgtattaagctcg
gcaagagatgagccctctggtcctgcacgatgtgtagcactttgtagtttaggtatttgg
atttgtgaagaactagtccatgagtctcatcatcctcaaattaaggaagctctgaatgtg
atttgtgtttccttaaagtttactaataaaacagtagcccacgtagcttgtaacatgctt
cacatgctggttcattatgtacctagacttcagatttaccagcctgattctcccttgaaa
attattcaaatcctaatagctaccatcacccatcttttaccaagtacagaggcttcatct
tatgaaatggacaagaggttggtagtatctttacttctctgccttctggactggatcatg
gccttacctctaaagacactgctccaaccatttcatgctacgggagcagaaagcgataaa
acagaaaaatctgttctcaattgcatttataaggttttacatgggtgtgtttatggagct
cagtgttttagcaatccaaggtattttcccatgagcctctctgatttggcatctgtagat
tatgatccttttatgcatttggaaagtctgaaagagcctgagcctctgcactctcctgac
tcagaacgatcttctaaactccagccagtaacagaagtgaaaactcaaatgcagcatgga
ttaatctctatagcagcccgcactgttattacacatctggtaaatcacctgggccattat
ccaatgagcggtggtcctgctatgctaacaagtcaggtgtgtgaaaatcacgacaatcat
tacagtgaaagtactgaactttctcctgaactctttgagagtccaaatatccagttcttt
gtgttaaataatacaaccttagtgtcctgtatccagatcagatcagaagagaatatgcct
ggaggaggtttatctgctggccttgcatcagccaattcaaatgtcagaatcatagtacgt
gatctctctggaaaatattcatgggattctgctatactgtatggcccacctcctgtaagt
ggcttgtcagaacctacatctttcatgctttcattgtctcaccaagagaagccagaagag
cctccgacatctaatgaatgcttagaagatataaccgtaaaagatggactttctctccag
tttaaaagatttagagaaactgtaccaacttgggatacaataagagatgaagaagatgtt
cttgatgagctcttgcagtatttgggtgttactagtcctgaatgcttacagagaactgga
atctcacttaatattcctgctccacaacctgtgtgcatttctgaaaaacaagaaaatgat
gttattaatgctatccttaagcaacatacagaagaaaaagaatttgttgagaagcacttt
aatgacttaaacatgaaagctgtggaacaagatgaaccaatacctcaaaaacctcagtca
gcattttattattgcagattgcttcttagtatattgggaatgaattcctgggacaaacgg
aggagctttcatctcctgaagaaaaatgaaaagctacttagagaacttaggaacttggat
tcaaggcagtgccgagagacacacaagattgcagtattttatgttgctgaaggacaagaa
gacaaacactccattctcaccaatacaggaggaagtcaagcatatgaagattttgtagct
ggtcttggttgggaggtaaatcttacaaaccattgtggttttatgggaggactacaaaaa
aacaaaagcactggattgaccactccatattttgctacctctacagtagaggtaatattt
cacgtgtcaacaagaatgccttctgattctgatgattctttgaccaaaaaattgagacat
ttgggaaatgatgaagtgcacattgtttggtcagagcatactagagactacaggagagga
attattcccacagaatttggtgatgtccttattgtaatatatccaatgaaaaatcacatg
ttcagtattcagataatgaaaaaaccagaggttcccttctttggtcccctttttgatggt
gctattgtgaatggaaaggttctacccattatggttagagcaacagctataaatgcaagc
cgtgctctgaaatctctgattccattgtatcaaaacttctatgaggagagagcacgatac
ctgcaaacaattgtccagcaccacttagaaccaacaacatttgaagattttgcagcacag
gttttttctccagctccctaccaccatttaccatctgatgccgatcattaa

KEGG   Homo sapiens (human): 57148
Entry
57148             CDS       T01001                                 
Symbol
RALGAPB, KIAA1219, RalGAPbeta
Name
(RefSeq) Ral GTPase activating protein non-catalytic subunit beta
  KO
K25769  Ral GTPase-activating protein subunit beta
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    57148 (RALGAPB)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    57148 (RALGAPB)
Membrane trafficking [BR:hsa04131]
 Exocytosis
  Tethering complex
   Exocyst complex assembly proteins
    57148 (RALGAPB)
SSDB
Motif
Pfam: RALGAPB_N Rap_GAP SOG2
Other DBs
NCBI-GeneID: 57148
NCBI-ProteinID: NP_001269846
OMIM: 618833
HGNC: 29221
Ensembl: ENSG00000170471
UniProt: Q86X10 Q6MZJ2
LinkDB
Position
20:38472843..38578858
AA seq 1494 aa
MYSEWRSLHLVIQNDQGHTSVLHSYPESVGREVANAVVRPLGQVLGTPSVAGSENLLKTD
KEVKWTMEVICYGLTLPLDGETVKYCVDVYTDWIMALVLPKDSIPLPVIKEPNQYVQTIL
KHLQNLFVPRQEQGSSQIRLCLQVLRAIQKLARESSLMARETWEVLLLFLLQINDILLAP
PTVQGGIAENLAEKLIGVLFEVWLLACTRCFPTPPYWKTAKEMVANWRHHPAVVEQWSKV
ICALTSRLLRFTYGPSFPAFKVPDEDASLIPPEMDNECVAQTWFRFLHMLSNPVDLSNPA
IISSTPKFQEQFLNVSGMPQELNQYPCLKHLPQIFFRAMRGISCLVDAFLGISRPRSDSA
PPTPVNRLSMPQSAAVSTTPPHNRRHRAVTVNKATMKTSTVSTAHASKVQHQTSSTSPLS
SPNQTSSEPRPLPAPRRPKVNSILNLFGSWLFDAAFVHCKLHNGINRDSSMTAITTQASM
EFRRKGSQMSTDTMVSNPMFDASEFPDNYEAGRAEACGTLCRIFCSKKTGEEILPAYLSR
FYMLLIQGLQINDYVCHPVLASVILNSPPLFCCDLKGIDVVVPYFISALETILPDRELSK
FKSYVNPTELRRSSINILLSLLPLPHHFGTVKSEVVLEGKFSNDDSSSYDKPITFLSLKL
RLVNILIGALQTETDPNNTQMILGAMLNIVQDSALLEAIGCQMEMGGGENNLKSHSRTNS
GISSASGGSTEPTTPDSERPAQALLRDYALNTDSAAGLLIRSIHLVTQRLNSQWRQDMSI
SLAALELLSGLAKVKVMVDSGDRKRAISSVCTYIVYQCSRPAPLHSRDLHSMIVAAFQCL
CVWLTEHPDMLDEKDCLKEVLEIVELGISGSKSKNNEQEVKYKGDKEPNPASMRVKDAAE
ATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKYSRLPTINKHSFRYFVLDNSVILAMLE
QPLGNEQNDFFPSVTVLVRGMSGRLAWAQQLCLLPRGAKANQKLFVPEPRPVPKNDVGFK
YSVKHRPFPEEVDKIPFVKADLSIPDLHEIVTEELEERHEKLRSGMAQQIAYEIHLEQQS
EEELQKRSFPDPVTDCKPPPPAQEFQTARLFLSHFGFLSLEALKEPANSRLPPHLIALDS
TIPGFFDDIGYLDLLPCRPFDTVFIFYMKPGQKTNQEILKNVESSRTVQPHFLEFLLSLG
WSVDVGRHPGWTGHVSTSWSINCCDDGEGSQQEVISSEDIGASIFNGQKKVLYYADALTE
IAFVVPSPVESLTDSLESNISDQDSDSNMDLMPGILKQPSLTLELFPNHTDNLNSSQRLS
PSSRMRKLPQGRPVPPLGPETRVSVVWVERYDDIENFPLSELMTEISTGVETTANSSTSL
RSTTLEKEVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVIN
ICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTSLFQEVGLKNCSS
NT seq 4485 nt   +upstreamnt  +downstreamnt
atgtactctgagtggaggtcactgcatttggtgattcagaatgatcaaggccataccagt
gtgctgcacagctatccagagagcgttggacgagaggtggcaaatgctgtagtccgtcct
cttgggcaggtgttaggtaccccttcagtggctggtagtgagaatttgttaaaaactgac
aaagaagtaaaatggaccatggaagtaatttgctatggactgacccttccattggatgga
gagactgtaaaatattgcgttgatgtatatacagactggattatggctttagtgttgcca
aaagattctattccattgccagttattaaagagcctaatcaatatgttcaaactatacta
aaacacctacagaatctttttgtaccaagacaggaacagggttccagtcagattcgacta
tgcttacaggtcctgagagccattcagaaactggcccgtgagtcatctctcatggcccga
gaaacttgggaagtcttactgttgtttcttctgcagattaacgacatacttctggcccca
ccaactgttcaaggtggcattgctgagaatctagcagagaagttgattggtgttctcttt
gaggtgtggttactagcttgtactcggtgcttcccaacacctccttattggaaaacagcc
aaggagatggtggctaactggaggcatcacccagcagtggtggagcagtggagcaaggtc
atttgtgcactcacttccagattgctacgctttacatatggtccttcatttcctgcattt
aaagttcccgatgaagatgccagtctgatccctccagaaatggataatgagtgtgttgca
cagacatggtttcgctttttacacatgttaagtaatcctgtggatttgagtaacccagct
attataagctctactcccaaatttcaggaacagttcttgaatgtgagcggaatgccgcaa
gaattgaatcagtatccctgccttaaacatctgcctcaaatattttttcgtgccatgcgt
ggaatcagctgtctggtggatgcattcttaggtatttctagaccccgatcagacagtgct
cccccaacacccgtgaatagattaagtatgcctcaaagtgctgctgtcagtaccaccccc
ccacataaccggaggcaccgggctgttactgtgaataaggccaccatgaagacaagcaca
gttagtactgctcatgcctctaaagttcagcaccagacgtcctccacctctcctctgtca
agtccaaatcagactagttcagaaccccggccactgcctgcccctcggagaccaaaggtt
aacagcatcttgaatctctttggatcatggttatttgatgcagcatttgttcactgtaaa
cttcataatgggataaacagagacagcagcatgactgccattacaacacaagctagcatg
gagtttcgacggaaagggtcacaaatgtccacagacaccatggtttccaatcctatgttt
gatgcaagtgaatttcctgataactatgaagcaggaagagctgaggcttgtgggacactg
tgtaggattttttgtagcaagaagactggagaagagattctgccagcttatttatccaga
ttttacatgcttttaattcaaggtttgcagataaatgattatgtgtgccatcctgtcttg
gccagcgttattctaaactctcctcctttgttctgctgtgacttgaaagggattgatgtt
gtggttccttactttatttcagctcttgaaaccattttgcctgacagagaactctcaaaa
ttcaaaagctatgtaaatccaacagaattgcgaagatcctccattaatatcctgctttct
ttgttgcccctccctcatcattttggcacagtcaaatctgaggtggtcctggaaggaaag
tttagtaacgatgacagctcttcttatgataaaccaataacttttctgtccctgaagttg
agacttgtgaatatattaataggtgccttgcaaactgaaacggaccccaacaacacccaa
atgatattaggggcaatgttaaatattgttcaagattcagcacttttggaagccattggt
tgccagatggagatgggtggtggagaaaataacctgaagagtcatagtcgcaccaatagt
ggtattagttcagcaagtggtggaagcacggagcccacgactcccgatagtgagagacct
gctcaagctctcttaagagattatgctcttaatacagattcagctgctgggctcctgatt
cgcagcattcatctcgtcacccaaagactcaactcccagtggcgccaagacatgagcata
tcactggcagctctagagctcctctctggccttgcaaaggtaaaagtgatggttgactca
ggagaccggaagcgagccatcagttctgtgtgcacctacattgtttatcagtgtagtcgg
ccagctcctttacactccagggatctgcactccatgatagtggcagcttttcagtgtctc
tgtgtctggctgacagagcaccctgatatgcttgatgaaaaggactgccttaaggaagta
ctggagattgtggaactgggtatctcaggaagtaagtccaagaacaatgagcaagaggtc
aagtacaaaggagataaggagccaaaccctgcatctatgagggtaaaggatgctgctgaa
gccaccctaacatgcattatgcagttgctcggcgcatttccttcacctagtggtcctgcc
tctccttgtagtcttgtgaatgagaccactttgattaaatactccaggctgccaaccata
aacaagcatagtttccggtactttgtcttggataacagtgtcatcctggcaatgctggaa
caacctcttggaaatgagcagaatgattttttcccctctgtcactgtgctggtccgggga
atgtctggaagacttgcttgggcacaacagctttgtcttttacccagaggagcaaaagca
aatcagaagctttttgtacctgaacctcgcccagttcctaaaaatgacgttggatttaaa
tattctgtgaaacatcggccatttcctgaagaggtggacaagattccttttgtgaaagca
gatctcagcattccagatttgcatgaaatagtcactgaagaattagaagagagacacgaa
aaattaaggagtggcatggcccagcagattgcttatgaaatacaccttgagcaacagagt
gaggaggaattgcagaagagaagttttcctgacccagttacggattgcaagcccccgcct
cctgcccaggaattccaaacagcccgcctttttctctcacactttggatttttgtcctta
gaagcactgaaggaacctgcaaatagtcgtctacctcctcaccttattgcacttgattcc
acgatacctggattttttgatgacattgggtatctggatctcttgccatgtcgtcctttt
gacacagtttttattttctatatgaagccaggtcagaaaacgaaccaagagattttaaag
aatgtggagtcttccagaactgttcagccacatttcctagaatttttgctttcccttggc
tggtcagtagatgtgggcagacaccctggttggactgggcatgtttctaccagttggtct
attaattgttgtgatgatggtgaaggatctcaacaagaagtgatttcctctgaagatatt
ggagctagcattttcaatggacagaagaaggtgctgtattatgctgatgcccttacagaa
attgcttttgtggttccttctcctgtggagtccttaactgattcattggaaagtaacatc
tcggaccaagatagtgattcaaatatggatcttatgccaggaattctgaaacagccatcc
ctgacacttgagcttttccccaatcatacagacaatcttaattcctcacagaggctcagt
cccagttccagaatgaggaagctgcctcagggtcgccctgttcctccccttggacctgag
acaagagtttctgtagtctgggtggaacgctatgatgatatagaaaactttcccctctca
gagctgatgacagagatcagtactggtgtggaaactactgcaaatagtagcacttcactg
agatctacaactcttgaaaaagaagttcctgtcatcttcatccaccctttaaacactgga
ttattccggataaaaattcaaggagccactggaaaatttaatatggtcatccctcttgtg
gatgggatgattgtcagcaggcgagctcttggctttctggtgaggcagactgtaattaac
atttgtagaagaaagagactggaaagtgactcctacagtcccccccatgtccgccggaaa
cagaaaatcaccgacattgtcaacaagtaccggaacaagcagctggagccagagttttat
acttcacttttccaggaggttggactcaagaactgcagttcttag

KEGG   Homo sapiens (human): 57186
Entry
57186             CDS       T01001                                 
Symbol
RALGAPA2, AS250, C20orf74, bA287B20.1, dJ1049G11, dJ1049G11.4, p220
Name
(RefSeq) Ral GTPase activating protein catalytic subunit alpha 2
  KO
K25768  Ral GTPase-activating protein subunit alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    57186 (RALGAPA2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    57186 (RALGAPA2)
Membrane trafficking [BR:hsa04131]
 Exocytosis
  Tethering complex
   Exocyst complex assembly proteins
    57186 (RALGAPA2)
SSDB
Motif
Pfam: Rap_GAP RALGAPB_N Nop16
Other DBs
NCBI-GeneID: 57186
NCBI-ProteinID: NP_065076
OMIM: 618836
HGNC: 16207
Ensembl: ENSG00000188559
UniProt: Q2PPJ7
LinkDB
Position
20:complement(20389530..20712644)
AA seq 1873 aa
MFSRRSHGDVKKSTQKVLDPKKDVLTRLKHLRALLDNVDANDLKQFFETNYSQIYFIFYE
NFIALENSLKLKGNNKSQREELDSILFLFEKILQFLPERIFFRWHYQSIGSTLKKLLHTG
NSIKIRCEGIRLFLLWLQALQTNCAEEQVLIFACLVPGFPAVMSSRGPCTLETLINPSPS
VADVKIYPEEITPLLPAISGEKIAEDQTCFFLQILLKYMVIQAASLEWKNKENQDTGFKF
LFTLFRKYYLPHLFPSFTKLTNIYKPVLDIPHLRPKPVYITTTRDNENIYSTKIPYMAAR
VVFIKWIVTFFLEKKYLTATQNTKNGVDVLPKIIQTVGGGAVQERAPELDGGGPTEQDKS
HSNSSTLSDRRLSNSSLCSIEEEHRMVYEMVQRILLSTRGYVNFVNEVFHQAFLLPSCEI
AVTRKVVQVYRKWILQDKPVFMEEPDRKDVAQEDAEKLGFSETDSKEASSESSGHKRSSS
WGRTYSFTSAMSRGCVTEEENTNVKAGVQALLQVFLTNSANIFLLEPCAEVPVLLKEQVD
ACKAVLIIFRRMIMELTMNKKTWEQMLQILLRITEAVMQKPKDKQIKDLFAQSLAGLLFR
TLMVAWIRANLCVYISRELWDDFLGVLSSLTEWEELINEWANIMDSLTAVLARTVYGVEM
TNLPLDKLSEQKEKKQRGKGCVLDPQKGTTVGRSFSLSWRSHPDVTEPMRFRSATTSGAP
GVEKARNIVRQKATEVEECQQSENAPAAGSGHLTVGQQQQVLRSSSTSDIPEPLCSDSSQ
GQKAENTQNSSSSEPQPIQENKGHVKREHEGITILVRRSSSPAELDLKDDLQQTQGKCRE
RQKSESTNSDTTLGCTNEAELSMGPWQTCEEDPELNTPTDVVADADARHWLQLSPTDASN
LTDSSECLTDDCSIIAGGSLTGWHPDSAAVLWRRVLGILGDVNNIQSPKIHARVFCYLYE
LWYKLAKIRDNLAISLDNQSSPSPPVLIPPLRMFASWLFKAATLPNEYKEGKLQAYRLIC
AMMTRRQDVLPNSDFLVHFYLVMHLGLTSEDQDILNTIIRHCPPRFFSLGFPGFSMLVGD
FITAAARVLSTDILTAPRSEAVTVLGSLVCFPNTYQEIPLLQSVPEVNEAITGTEDVKHY
LINILLKNATEEPNEYARCIAVCSLGVWICEELAQCTSHPQVKEAINVIGVTLKFPNKIV
AQVACDVLQLLVSYWEKLQMFETSLPRKMAEILVATVAFLLPSAEYSSVETDKKFIVSLL
LCLLDWCMALPVSVLLHPVSTAVLEEQHSARAPLLDYIYRVLHCCVCGSSTYTQQSHYIL
TLADLSSTDYDPFLPLANVKSSEPVQYHSSAELGNLLTVEEEKKRRSLELIPLTARMVMA
HLVNHLGHYPLSGGPAILHSLVSENHDNAHVEGSELSFEVFRSPNLQLFVFNDSTLISYL
QTPTEGPVGGSPVGSLSDVRVIVRDISGKYSWDGKVLYGPLEGCLAPNGRNPSFLISSWH
RDTFGPQKDSSQVEEGDDVLDKLLENIGHTSPECLLPSQLNLNEPSLTPCGMNYDQEKEI
IEVILRQNAQEDEYIQSHNFDSAMKVTSQGQPSPVEPRGPFYFCRLLLDDLGMNSWDRRK
NFHLLKKNSKLLRELKNLDSRQCRETHKIAVFYIAEGQEDKCSILSNERGSQAYEDFVAG
LGWEVDLSTHCGFMGGLQRNGSTGQTAPYYATSTVEVIFHVSTRMPSDSDDSLTKKLRHL
GNDEVHIVWSEHSRDYRRGIIPTAFGDVSIIIYPMKNHMFFIAITKKPEVPFFGPLFDGA
IVSGKLLPSLVCATCINASRAVKCLIPLYQSFYEERALYLEAIIQNHREVMTFEDFAAQV
FSPSPSYSLSGTD
NT seq 5622 nt   +upstreamnt  +downstreamnt
atgttctcccgaaggagccacggggatgtgaagaagtccacccagaaggtgctggacccg
aagaaggacgtgctgacccgcctgaagcacctgcgggcgctgctggataatgtggatgca
aatgatcttaagcagttttttgagaccaactattctcagatatatttcatcttctatgaa
aattttatagcactggaaaatagtttgaaattaaaagggaataataagtcacaaagggag
gagctggactccatcctcttcctttttgaaaaaatactgcagtttctacctgaacgaatt
ttctttcgatggcattaccagagtataggctcaactttaaagaagcttctacacactgga
aattctattaagataagatgtgaaggaatcaggctgtttcttctgtggcttcaagcactt
cagacaaactgtgcagaagagcaggttctgatttttgcttgcctggtgcctggtttccca
gcagtcatgtcatccaggggcccttgcacactggagacactcatcaatcccagccctagt
gtagctgatgtaaagatatatccagaagaaatcactccactcctaccagccatatcaggg
gagaagattgctgaggaccaaacctgcttttttcttcaaatactgttgaagtatatggtt
attcaggctgcgagcttggagtggaagaataaggagaatcaagatactggttttaaattt
ctttttacattgtttcgaaagtattatcttcctcatttatttccatcatttactaagtta
acaaacatctacaaacctgtacttgacatcccccatttgagaccaaagcctgtgtacatt
actaccactcgagacaatgagaacatttacagtacaaagattccatatatggcagctcgt
gttgtttttattaagtggattgtaaccttctttttggaaaaaaagtatctaactgcaaca
caaaacactaaaaatggagttgatgtattgcctaaaatcatccagactgttggtggtggt
gctgtgcaggagagagcgcctgagctggatggtggtgggcccacggagcaggacaaaagc
cattctaacagcagcaccttgtcggaccgaagactcagcaactccagcctctgtagcatt
gaagaagagcaccgaatggtgtatgaaatggtacagcggattctcttgtcaacacgaggt
tatgtcaacttcgtgaatgaagtatttcaccaggcatttttgttgccttcctgtgagata
gctgtaacaagaaaagtagttcaagtgtacagaaagtggattctccaggacaaacctgtg
ttcatggaggagccagatagaaaagatgttgcccaagaagatgctgaaaaattaggattt
tccgagactgatagcaaggaggcctcatctgaaagttctggtcataaacgatcttccagt
tggggacgcacatactccttcacaagtgcaatgagcagagggtgtgtgacagaggaggaa
aatacaaatgtgaaagccggcgtccaggctttgttgcaggtatttttgacgaactctgca
aacatctttttgttggaaccatgtgctgaagttcctgtgctcttgaaagaacaagttgat
gcttgtaaagctgttttgattatttttaggcgcatgataatggagcttacaatgaataaa
aagacatgggaacagatgttgcaaatactactcaggataacagaagctgtcatgcagaag
ccaaaggataaacaaataaaggacttgtttgcccagagcttggcagggttactatttagg
acgctcatggtagcttggatccgagcaaacctctgtgtgtacatttctcgagagctctgg
gatgactttcttggtgtgctgtcctccctcacggaatgggaggaacttataaacgagtgg
gccaacattatggactccttgacagcagtgcttgcaagaaccgtttatggagttgagatg
acaaacctacctctggataaattaagtgaacaaaaggaaaagaagcaacgaggcaaaggc
tgtgttctagatcctcagaaaggaaccaccgtggggaggtccttttctctcagctggcgg
agccacccagatgtgaccgaaccgatgcgatttaggagtgccaccacgtctggagcaccg
ggagtggaaaaggcaagaaatattgttcgccaaaaagcaactgaagtggaggagtgtcaa
cagtcagaaaatgcacctgcagccggatctggccatctcacagtgggacagcagcagcag
gtccttcggagcagcagcacctccgacatccccgagccgctgtgctcagattcttctcag
ggtcaaaaggcagaaaacacacagaattcgagttcttcagagcctcagcctattcaagag
aataaaggacatgtgaagagagaacatgaaggaataacaatcttagttcgaagaagcagc
agccctgctgaattggatttgaaagatgatttgcagcagacacaaggaaaatgtagggaa
agacagaagagtgaaagtaccaacagtgacacaactctgggctgtaccaatgaggcagag
ctgtccatgggcccatggcagacctgtgaggaagacccagaactgaatactcccacagat
gttgtggctgatgctgatgcccgtcattggttacaactgagtcccaccgatgcttcaaat
ttaacagatagcagcgagtgcctcacagatgactgtagtataatcgccggggggagcctc
actggttggcacccagactctgctgctgtgttatggcgaagggtcttggggatcctcgga
gatgtgaataacatccagtcacccaagatccatgccagagttttctgctatctctatgaa
ctctggtacaaactagcaaagatacgggataatctagcaataagcctggataaccagtct
tctccatctcctccagttttgatcccaccactcagaatgtttgcatcatggctgtttaag
gcggcgacactgccaaatgaatataaggaaggcaaactacaagcctacaggctgatctgt
gccatgatgaccagacgccaggacgttctgccaaactcagatttcctggtgcatttttac
cttgtgatgcacctgggattaaccagcgaggatcaggatatcttaaatacgatcataagg
cactgtccaccccgctttttctccctgggttttcctggcttctcaatgctggtgggggac
ttcatcacggccgctgccagggtccttagcacagacattttgacggcgcctcgttcagag
gctgtcactgtcctcggctctctggtctgctttccaaatacctaccaggagattccttta
ctgcagtcagtgccagaagtaaatgaggccattacaggaactgaagatgtcaagcattac
ctcataaatattttactgaagaatgccacagaagaaccaaatgaatatgcaagatgcatt
gctgtttgctcccttggggtctggatatgtgaagagcttgcacagtgtacaagccaccct
caggtgaaagaggccatcaatgtgataggagtaactctgaagtttcccaacaaaatcgtg
gcccaggtagcttgcgatgtccttcagttgctggtttcctactgggagaagcttcagatg
tttgaaacctctctgcctcggaaaatggcagaaatcctcgtggccacagttgcttttctt
ttaccaagtgcagagtactcctcagtggaaacagacaagaagtttattgtgtccttgcta
ctctgcctcttggactggtgcatggcattgcccgtgagtgtccttctccaccccgtgtcc
acagcagtcctagaggagcagcattcggccagagcccccttgctggattatatctacagg
gttttgcactgctgtgtgtgtggctcaagcacgtacacccaacagagtcactacatactg
accctggctgacttgtcatccacggattatgaccccttcctgccactggcaaatgtgaag
agctctgagccagtccagtatcattcatcagcagaattgggtaacctgctgactgttgaa
gaggagaagaagagaagaagtttggagttgatccctttgactgctcgaatggtgatggcc
cacctggtgaaccacctggggcactaccccctcagtgggggccctgccatactgcacagc
cttgtcagcgagaaccatgacaatgcccatgtggaaggctccgagctgtcctttgaggtg
ttcagaagtccaaacctgcagctgtttgtatttaatgatagcaccctcatctcctacctt
cagacacccacagaaggaccggtagggggatcaccagtgggctctctctctgatgtgaga
gtaattgtgagggatatctcagggaagtactcttgggatggtaaggttttatatggacct
ttggaaggctgcttagcacccaatggaagaaatccttcatttctgatttcgagctggcat
cgtgacacatttggacctcagaaagactcttctcaagttgaggagggggatgatgttctt
gacaaattacttgaaaacattggccatacaagtcctgaatgccttttaccgtcacagcta
aatctaaatgaaccttccctaaccccatgtggcatgaactatgaccaagagaaggaaatc
attgaggtcattttgcgccaaaatgctcaagaggatgagtatatccagagtcataacttc
gattctgcaatgaaagtcaccagccaagggcagccctccccagtggagccccgaggaccc
ttttatttctgcaggttattgcttgatgacttgggaatgaattcttgggacagaaggaag
aattttcatctattgaagaaaaattcaaaattattgagagagctgaaaaatttggactcc
cgccagtgccgtgagacacacaaaatcgcagtgttttacattgctgaaggtcaagaagac
aagtgttcaatcctctctaatgaaagaggaagccaagcatatgaagactttgttgctgga
cttggatgggaggtggatctctccacccactgtgggttcatgggtggccttcagcgcaat
ggcagcaccgggcagacggccccttactatgctacctcaactgtggaagtgattttccat
gtttccactcgaatgccgtcagactcagatgattccctcaccaaaaagcttcgtcacttg
gggaatgacgaggtccatatcgtctggtctgaacactccagagactaccgcaggggtatt
atcccaactgcctttggagatgtttcaatcattatttacccaatgaagaatcacatgttc
ttcatcgcgataacgaagaaacctgaggttccattttttgggcctctgtttgatggagcc
atagtgagtgggaagctgctgccaagccttgtatgtgccacgtgcatcaacgccagcagg
gctgtgaagtgcctcatcccactctaccagagcttctatgaagagcgagctctgtatctc
gaagcaataattcagaaccaccgcgaagtaatgacattcgaggatttcgcagcccaagtc
ttttctccctctcccagctactccctcagcggaacggattaa

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